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All Journal Indonesian Journal of Cardiology Sumatera Medical Journal Heart Science Journal Cardiovascular and Cardiometabolic Journal (CCJ) Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)
Sarastri, Yuke
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Patient-reported perceptions of life quality and longevity in chronic heart failure Lubis, Ahmad Feriansyah; Lubis, Anggia Chairuddin; Andra, Cut Aryfa; Raynaldo, Abdul Halim; Ardini, Tengku Winda; Haykal, Teuku Bob; Sarastri, Yuke
Heart Science Journal Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.04.9

Abstract

BACKGROUND: Although heart failure therapy has advanced, many patients still experience functional limitations, which impact their quality of life. OBJECTIVES: To explore the factors influencing heart failure patients' preferences for quality of life and longevity. METHODS: This cross-sectional study was conducted at Adam Malik Hospital, Medan, Indonesia. The study was conducted from April 2023 to October 2023. A total of 143 chronic heart failure patients were included using purposive sampling. Data were collected through interviews and the EuroQol five-dimension five-level questionnaire, EuroQol visual analogue scale, and the Time Trade-Off method. Statistical analysis was performed using multivariate logistic regression. RESULTS: Of the 143 patients, 66.4% preferred quality of life over longevity, and 47.3% were willing to trade two years of their lives for a better quality of life. The main factors associated with this preference were heart failure with reduced ejection fraction (OR: 3.554; 95% CI: 1.373 - 9.198; p: 0.009), diabetes mellitus (OR: 2.705; 95% CI: 1.108 - 6.602; p: 0.029), and lower visual analog scale scores (OR: 0.889; 95% CI: 0.848 - 0.932; p: 0.000). Our results also showed that patients in the longevity group had better ejection fractions, fewer rehospitalizations, and were less likely to have diabetes mellitus or chronic kidney failure compared to the quality of life group. CONCLUSION: The majority of heart failure patients choose quality of life over longevity, and this may be influenced by symptom burden and rehospitalization history. These findings emphasize the importance of patient-centered therapy focusing on symptom management and psychosocial support.
Association of GWTG-HF Risk Score with Major Adverse Cardiovascular Events in Acute Heart Failure Patients: A Retrospective Study in a Tertiary Hospital in Indonesia Sumbayak, Novra Christy Grace; Hasan, Refli; Raynaldo, Abdul Halim; Haykal, Teuku Bob; Nasution, Ali Nafiah; Sarastri, Yuke
Journal of Society Medicine Vol. 4 No. 12 (2025): December
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i12.250

Abstract

Introduction: Heart failure (HF) affects approximately 64 million people globally, contributing to high mortality, morbidity, reduced quality of life, and substantial healthcare burden. Acute heart failure (AHF) requires urgent intervention and carries elevated risks of mortality and major adverse cardiovascular events (MACE). The Get With The Guidelines-Heart Failure (GWTG-HF) risk score, originally developed for predicting in-hospital mortality in HF patients, has shown potential in forecasting MACE in certain populations. However, its association with MACE in Indonesian AHF patients remains underexplored. Method: This retrospective observational cohort study included 319 AHF patients admitted to Adam Malik General Hospital, Medan, Indonesia, from January 2024 to March 2025. Patient characteristics, GWTG-HF scores, and in-hospital MACE were recorded. Statistical analyses involved receiver operating characteristic (ROC) curves and multivariate regression. Results: Patients had a mean age of 55 years, with 54.5% males. Median hospital stay was 5 days (range 1–47). Predominant features included acute decompensated HF (65.8%), infection as etiology (46.7%), HFrEF (52.0%), coronary heart disease (62.4%), and smoking (50.8%). In-hospital MACE occurred in 20.4% of patients, primarily mortality (18.8%), increasing with GWTG-HF risk categories (low: 8.1%; moderate: 17.4%; high: 36.7%). Age, systolic blood pressure, heart rate, sodium, and blood urea nitrogen significantly influenced MACE (p<0.05). The GWTG-HF score demonstrated good predictive performance for MACE (AUC 0.759, p<0.001; sensitivity 63.2%; specificity 78.1%). Conclusion: The GWTG-HF score is significantly associated with in-hospital MACE in Indonesian AHF patients, supporting its utility as a risk stratification tool to guide clinical decisions and optimize management.
Renal Function and Left Ventricular Ejection Fraction in Diabetic Patients with Acute Heart Failure Hutapea, Mery Natalia; Hasan, Refli; Raynaldo, Abdul Halim; Siregar, Abdullah Afif; Haykal, Teuku Bob; Sarastri, Yuke; Ardini, Tengku Winda; Ketaren, Andre Pasha; Purba, Joy Wulansari; Akbar, Nizam Zikri; Andra, Cut Aryfa
Sumatera Medical Journal Vol. 9 No. 1 (2026): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v9i1.22989

Abstract

Background: Acute heart failure (AHF) in patients with type 2 diabetes mellitus (T2DM) is frequently complicated by renal dysfunction, which may aggravate cardiac impairment. Serum creatinine may reflect this cardio–renal interaction, but its association with left ventricular ejection fraction (LVEF) in AHF patients with T2DM remains unclear. Objective: To investigate the correlation between serum creatinine and left ventricular ejection fraction (LVEF) in patients with acute heart failure (AHF) and type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study of 52 hospitalized AHF patients with T2DM. Clinical data, serum creatinine, A1C, and echocardiographic LVEF (assessed by two independent consultants) were collected. Correlation and multivariable linear regression analyses were performed. Results: The patients were middle-aged and predominantly male. Mean LVEF was 33.2 ± 9.1%, and mean serum creatinine was 1.58 ± 0.31 mg/dL. Higher serum creatinine levels were strongly associated with lower LVEF. Glycemic status (A1C) and urea levels also showed negative associations with LVEF. After adjustment, serum creatinine and A1C remained independent predictors of reduced LVEF. Conclusion: In AHF patients with T2DM, higher serum creatinine and A1C levels are independently associated with reduced LVEF, underscoring the cardio-renal-metabolic interplay in this population and highlighting the need for integrated management strategies.
Co-Authors Akbar, Nizam Zikri Andra, Cut Aryfa Ardini, Tengku Winda Arifianto, Habibie Batubara, Gio Justisia Chan, Muhammad Ikhsan Dewita, Auliya Ferhat E.S, Muhammad Hasan, Harris Hasan, Refli Hasanah, Dian Yaniarti Haykal, T. Bob Hutapea, Mery Natalia Ilyas, Kamal Kharazzi Ilyas, Kamal Kharrazi Ketaren, Andre Pasha Khaidirman, Sophia Khairina Khairunnisah, Dina Leonardo Paskah Suciadi Lubis, Ahmad Feriansyah Lubis, Anggia Chairuddin Lubis, Dian Anindita Mukhtar, Zulfikri Napitupulu, Bertha Gabriella Nasution, Ali Nafiah Prameswari, Hawani Sasmaya Pratikto, Rarsari Soerarso Purba, Antonius Leonardo Purba, Joy Wulansari Putri, Vebiona Kartini Prima Raynaldo, Abdul Halim Reynaldo, Abdul Halim Rialdy, M. Isfan Safri, Zainal Siregar, Abdullah Afif Sitepu, Andika Siti Elkana Nauli Soedarsono, Wahyu Aditya Sumbayak, Novra Christy Grace Tarigan, Stefanie Teuku Bob Haykal Yamin, Paskariatne Probo Dewi Yasmine Fitrina Siregar Zulkarnain, Edrian