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All Journal BALI MEDICAL JOURNAL (BMJ) Medicina INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES E-Jurnal Medika Udayana Medical Journal of Indonesia MNJ (Malang Neurology Journal) Bali Journal of Anesthesiology The Indonesian Journal of Infectious Diseases Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Kedokteran Neurosains Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indonesian Archives of Biomedical Research (InABR) Cermin Dunia Kedokteran Magna Neurologica Neurona
Raka-Sudewi A. A.
Udayana University, Bali-Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Other

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Journal : Magna Neurologica

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Profile of HIV/AIDS Patients with Neurological Manifestations in The Tertiary Referral Hospital in Bali Suryapraba, Anak Agung Ayu; Vania, Aurelia; Sudewi, Anak Agung Raka; Sukmawati, Ni Made Dewi Dian; Susilawathi, Ni Made
Magna Neurologica Vol. 2 No. 2 (2024): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i2.1097

Abstract

Background: Neurological manifestations in approximately half of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) patients are related to high morbidity and mortality worldwide. Therefore, there is a need for epidemiological data on HIV/AIDS patients with neurological manifestations in Bali, as an international tourism destination.  Objective: This study aimed to describe the clinical profile of neurological manifestations among patients with HIV/AIDS in the tertiary referral hospital for Bali and Nusa Tenggara region. Methods: A descriptive-retrospective study was conducted on HIV/AIDS patients presenting with neurological manifestations hospitalized in the Neurology Department of Prof. Dr. I.G.N.G Ngoerah Hospital Denpasar from January 2018 to December 2021. Results: Among the 227 subjects included in this study, the majority were male (69.9%) and HIV positive newly diagnosed (69.2%). Furthermore, out of 126 subjects who had CD4 data, the majority were with CD4 <200 cells/mm3 (85.7%) and 53.1% were <50 cells/mm3, with ages ranging from 18 to 67 years old, at a median of 36 years old. The most common neurological signs and symptoms found were paresis/paralysis (61.7%), headache (54.6%), decreased consciousness (52.9%), and cranial nerve palsy (52%). Cerebral toxoplasmosis (67.4%) and tuberculous meningoencephalitis (20.3%) were the prevalent opportunistic infections, while the mortality rate was 39.6% with sepsis as the major cause. Conclusions: Neurological manifestations are common initial symptoms in diagnosing HIV infection. Therefore, better awareness and earlier detection are required among people with risk factors of HIV transmission, particularly in groups of young and productive age with signs of immunocompromised condition as well as neurological manifestations.
Co-Authors Adinda Putra Pradhana Agung Bagus S. Satyarsa Agus Eka Darwinata Akira Ito Anak Agung Bagus Ngurah Nuartha Anak Agung Ngurah Subawa Angelia Carolin Bagiada I N. A. Christine Ekawati, Christine Christopher Ryalino Cokorda Istri Dyah Sintarani Sintarani Dedi Silakarma Desak Gde Diah Dharma Santhi Dewa Ngurah Suprapta Djoenaidi Widjaja Ernesta Ginting F. S. Wignall Ge Aris Geson Ginting, Ernesta Gitari, Ni Made I Dewa Made Sukrama I Gde Raka Widiana I Gede Ketut Sajinadiyasa I Gusti Kamasan Nyoman Arijana I Gusti Ngurah Kade Mahardika I Ketut Suastika I Made Jawi I Nyoman Adi Putra I Putu Eka Widyadharma I Wayan Niryana I Wayan Putu Sutirta Yasa I. B. P. Dwija Ida Ayu Jasminarti Dwi Kusumawardani Ida Ayu Sri Wijayanti Ida Bagus Ngurah Rai Imelda, Yuliana Monika Ivan Elisabeth Purba K. Subrata K. Wirasandhi Kade Agus Sudha Naryana Kazuhiro Nakaya M Wiryana Made Nyandra Made Wiryana N ADIPUTRA, N N. K. Susilarini NFN Moestikaningsih Ni Luh Putu Eka Arisanti Ni Made Adi Tarini Ni Made Susilawathi Ni Nengah Dwi Fatmawati Ni Nyoman Sri Budayanti Ni Putu Sriwidyani Ni Wayan Candrawati Oka Adnyana Pangkahila W Paramita, Dyah Pradnya Pramitasuri, Tjokorda Istri Pusaka, Semerdanta Putra Martin Widanta IGN Putu Yogi Pramana Sanjaya, Feliani Senja Decy Ningrum Sri Maliawan Sukmawati, Ni Made Dewi Dian Suryapraba, Anak Agung Ayu Susilawathi, Ni Made Thomas Eko Purwata Tjokorda Gde Agung Senapathi Tjokorda Gde Bagus Mahadewa Tjokorda Istri Pramitasuri Toni Wandra Vania, Aurelia Widanta IGN, Putra Martin Yasuhito Sako Yuliana Monika Imelda