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All Journal EMBRIO : Jurnal Kebidanan Conference on Innovation and Application of Science and Technology (CIASTECH) Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Care : Jurnal Ilmiah Ilmu Kesehatan Jurnal Ners Bubungan Tinggi: Jurnal Pengabdian Masyarakat Poltekita: Jurnal Pengabdian Masyarakat MAHESA : Malahayati Health Student Journal Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Media Husada Journal of Community Service Jurnal Vokasi Kesehatan Journal Research Midwifery Politeknik Tegal Media Husada Journal of Midwifery Science
Dwi Norma Retnaningrum
STIKES WIDYAGAMA HUSADA MALANG
Agriculture, Biological Sciences & Forestry Dentistry Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pengaruh Ekstrak Virgin Olive Oil (EVOO) terhadap Ekspresi Nuclear Factor Kappa Beta (NF-kB) pada Tikus Rattus Novergicus Model Preeklamsia Dwi Norma Retnaningrum; Wenny Rahmawati
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.46795

Abstract

Preeclampsia is a serious condition that threatens the safety of pregnant women worldwide. This condition causes high blood pressure and organ dysfunction in pregnant women who have reached 20 weeks of gestation. One of the main causes of preeclampsia is cellular damage due to free radicals and inflammation in the body, which can be detected through increased levels of NF-kB protein that triggers inflammation. This research examines the benefits of extra virgin olive oil (EVOO) in addressing this problem. Extra virgin olive oil was chosen because it is rich in polyphenol compounds that can fight free radicals and reduce inflammation. The researchers wanted to prove whether giving extra virgin olive oil could reduce NF-kB protein levels in the placenta of experimental rats experiencing preeclampsia-like conditions. The study was conducted by comparing five groups of pregnant rats: a group without treatment, a group induced to develop preeclampsia, and three groups given extra virgin olive oil at different doses (0.5 mL, 1 mL, and 2 mL per day). The research results showed that extra virgin olive oil administration was proven effective in reducing NF-kB protein levels in rat placenta, and the higher the dose given, the better the results. These findings provide hope that extra virgin olive oil can be a safe and natural complementary treatment option to help reduce inflammation in pregnant women with preeclampsia. This research paves the way for utilizing natural ingredients in preventing and managing preeclampsia, which ultimately can help save the lives of mothers and babies.
The Relationship Between Maternal Mental Health and Estimated Fetal Weight (EFW) in Second- and Third-Trimester Pregnant Women Inggrid Wuri Wulansari; Ervin Rufaindah; Dwi Norma Retnaningrum
Media Husada Journal of Midwifery Science Vol. 4 No. 1 (2026): Januari
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v4i1.38

Abstract

Maternal mental health during pregnancy is a crucial factor affecting both maternal and fetal well-being, including the estimated fetal weight (EFW). Unaddressed mental health issues such as stress, anxiety, and depression can increase the risk of fetal growth restriction and preterm birth. This study aimed to determine the relationship between maternal mental health and EFW in second and third trimester pregnant women at the Maternity Clinic of Dr. Saiful Anwar General Hospital Malang. This study employed a quantitative method with a cross-sectional design. The study population consisted of all second and third trimester pregnant women who had antenatal check-ups at the maternity clinic. A non-probability purposive sampling technique was used, resulting in a total of 34 respondents. The instrument used to measure mental health was the Mental Health Continuum–Short Form (MHC-SF), and the Hadlock chart was used to estimate EFW based on ultrasonographic measurements. Data were analyzed using the Spearman rank correlation test. The results shows that most respondents has flourishing mental health and most EFWs are in the normal category. Based on statistical analysis, a significant relationship is found between maternal mental health and EFW (p-value < 0.05). It can be concluded that there is a relationship between maternal mental health and EFW in second and third trimester pregnant women. Health workers are advised to pay greater attention to the psychological condition of pregnant women during antenatal care to prevent fetal complications.
Co-Authors Alfima Rahasti Alfima Rahasti Inggrid Wuri Wulansari Jayanti, Nicky Danur Mayasari, Senditya Indah Mizam Kurniyanti Patemah Patemah, Patemah Putri Febrianti Rufaindah, Ervin Wenny Rahmawati