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Management of diabetic foot ulcers: dermatology perspective Daryago, Adi Agung Anantawijaya; Fitriani, Fitriani; Kartowigno, Soenarto; Aryani, Inda Astri; Yahya, Yulia Farida; Diba, Sarah; Stephanie, Aurelia
Bali Dermatology and Venereology Journal Vol 4, No 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.65

Abstract

Diabetes mellitus (DM) is a chronic and complex disease that affects various parts of the body. It can lead to multiple systemic complications and also cutaneous manifestation. Diabetic foot ulcer (DFU) is one of the most devastating complications of DM in dermatology. The main etiology is an increase in plasma glucose, risk factors, or comorbidities due to DM itself. Neglected DFU can lead to further complications, including high amputation and mortality rates; thus, the healing of ulcers is the main objective of the treatment. Management is divided into the standard of care and adjuvant therapies. This study aims to optimize DFU management, so it can provide proper treatment and prevent complications.
Diagnosis and Management of Hair Loss in Pediatric Fitriani, Fitriani; Antonius, Cayadi Sidarta; Kartowigno, Soenarto; Diba, Sarah; Argentina, Fifa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.142-148

Abstract

Background: Hair loss can occur in pediatric and adult populations and may have different patterns. The causes of hair loss in pediatric patients include tinea capitis, alopecia areata, telogen effluvium, traction alopecia, anagen effluvium, androgenetic alopecia, loose anagen syndrome, short anagen syndrome, congenital aplasia cutis, congenital triangular alopecia, atrichia congenita, congenital hypotrichosis, and transient neonatal hair loss.Purpose: to understand etiologies of hair loss in pediatrics, and to determine the appropriate examinations for diagnosing and managing hair loss in children.Review: Hair loss in children can be categorized as congenital or acquired. Congenital hair loss is classified based on distribution, while acquired hair loss is classified as either scarring or non-scarring. Hair loss complications in children can be irreversible. The diagnosis of hair loss in pediatric patients includes anamnesis, physical examination, and supporting examinations. The supporting examinations used for diagnosis include fungal cultures, hair pull tests, hair tug tests, light microscopy, and trichoscopy. Conclusion: There are numerous causes of hair loss in pediatric patients that need to be identified before appropriate management can be implemented. The management of hair loss requires a holistic approach, including psychosocial support. Correct diagnosis and treatment of pediatric hair loss can prevent a decrease in the patient's quality of life.
Diagnosis dan Tatalaksana Pioderma Gangrenosum Terkini Diba, Sarah; Yonathan, Erico Lemuel; Thaha, M. Athuf; Nopriyati, Nopriyati; Kartowigno, Soenarto; Devi, Mutia
Media Dermato-Venereologica Indonesiana Vol 52 No 3 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i3.525

Abstract

Pioderma gangrenosum (PG) adalah dermatosis neutrofilik, secara klinis ditandai dengan ulkus kulit nyeri dan berkembang cepat dengan tepi tidak rata, tidak teratur, berwarna ungu kemerahan. Diagnosis PG sulit ditegakkan karena menyerupai penyakit lain, belum ada pemeriksaan baku emas untuk penegakan diagnosis definitif, kriteria diagnosis PG banyak dan bervariasi, sehingga diagnosis perlu ditegakkan sedini mungkin untuk memungkinkan penatalaksanaan yang tepat dan mencegah progresivitas penyakit. Diagnosis PG dibuat dengan menyingkirkan diagnosis lain. PARACELCUS merupakan kriteria diagnostik PG yang dianggap terbaik dan sederhana. Tata laksana PG dipilih berdasarkan tingkat keparahan dan perkembangan penyakit. Tata laksana umum terdiri dari rawat inap, eksklusi penyebab ulkus lain, mengontrol penyakit penyerta, tata laksana komorbiditas, menghindari trauma, tata laksana nyeri, perawatan luka adekuat, pengendalian infeksi penyerta, terapi kompresi untuk mengurangi edema, menjaga kecukupan nutrisi, menghentikan rokok, dan mengontrol glukosa darah. Tata laksana khusus terdiri dari terapi topikal, sistemik, terapi target, dan intervensi. Tata laksana PG masih terus dikembangkan melalui berbagai uji klinis. Pioderma gangrenosum memiliki angka mortalitas dan morbiditas signifikan dengan tingkat rekurensi tinggi sehingga diperlukan diagnosis tepat dan tata laksana segera. 
Effectiveness of 5% Channa Striata Extract Gel in Wound Healing: A Double-blind Randomized Controlled Trial Yahya, Yulia Farida; Kurniawati, Yuli; Bahar, Erial; Toruan, Theresia Lumban; Kartowigno, Soenarto; Purwoko, Muhammad Izazi Hari; Octyvani, Tiar Marina
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Snakehead fish (Channa striata, CS) has traditionally been used in Indonesia as a nutrient to promote wound healing. It contains protein highly similar to human protein, which may be involved in wound healing via biological pathways. We aim to determine the effectiveness of the topical 5% CS extract gel in promoting wound healing. Methods: A double-blind, placebo-controlled randomized clinical trial was conducted from June to August 2022 at the Department of Dermatology, Venereology, and Aesthetics of Dr. Mohammad Hoesin Hospital. We allocated 32 post-skin surgery participants with grade I acute superficial wounds on the face, neck, trunk, and extremities into 2 groups with one receiving 5% CS (n=16) and the other receiving placebo (n=16). Both groups applied the treatments twice daily. Assessments of wound healing using modified REEDA (redness, edema, ecchymosis, drainage, approximation) score, wound size, and adverse effects were done at follow-up days 1, 3, and 7. Results: Both groups showed REEDA score improvements on days 1, 3, and 7, with significant difference between both groups identified on day 3 (p=0.038). Wound size improved at each follow-up in all participants, with the 5% CS group being slightly better than the placebo group on day 3 (p>0.05). A mild adverse event was found in only one participant in the 5% CS group (3.1%). Conclusion: Both 5% CS extract gel and placebo had good safety profile and were effective in promoting wound healing. 5% CS extract gel was better at reducing REEDA score.