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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Bali Dermatology and Venereology Journal Cermin Dunia Kedokteran Media Dermato-Venereologica Indonesiana
Stephanie, Aurelia
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Selection of topical corticosteroids in children atopic dermatitis Stephanie, Aurelia; Sudarsa, Prima Sanjiwani Saraswati; Rusyati, Luh Mas
Bali Dermatology and Venereology Journal Vol 2, No 2 (2019)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v2i2.30

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that typically starts in childhood with classic symptoms of dry and itchy skin that occurs continuously and recurrences and even causes sleep disorders and skin that is susceptible to infection. AD sufferers often have atopic comorbidities such as asthma and allergic rhinitis in themselves and their families. The effects of this itching cycle result in growth disturbance and decreased quality of life for AD patients and their parents. Moderate and severe AD have an impact on parents, the stress in medication, and care, which takes up time and money. Atopic dermatitis is due to damage to the skin barrier, so the principle of management is to improve the skin barrier so that the inflammatory process can be avoided. The course of AD is chronic and relapsing; generally, patients come for treatment with an acute phase that sometimes requires topical corticosteroids. However, topical corticosteroids (TC) are used only to treat the acute phase for a short period. After the acute lesions have subsided, corticosteroids can be stopped immediately to prevent side effects and continue with daily skincare.Conclusion: Topical corticosteroids are first-line therapy in the acute phase. The choice of TC is based on age, body location, dosage, and severity of AD. If the acute lesion has subsided, then corticosteroids can be stopped and substituted with other antipruritic therapy and moisturizer.
Management of diabetic foot ulcers: dermatology perspective Daryago, Adi Agung Anantawijaya; Fitriani, Fitriani; Kartowigno, Soenarto; Aryani, Inda Astri; Yahya, Yulia Farida; Diba, Sarah; Stephanie, Aurelia
Bali Dermatology and Venereology Journal Vol 4, No 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.65

Abstract

Diabetes mellitus (DM) is a chronic and complex disease that affects various parts of the body. It can lead to multiple systemic complications and also cutaneous manifestation. Diabetic foot ulcer (DFU) is one of the most devastating complications of DM in dermatology. The main etiology is an increase in plasma glucose, risk factors, or comorbidities due to DM itself. Neglected DFU can lead to further complications, including high amputation and mortality rates; thus, the healing of ulcers is the main objective of the treatment. Management is divided into the standard of care and adjuvant therapies. This study aims to optimize DFU management, so it can provide proper treatment and prevent complications.
Tatalaksana Alopesia Androgenetik Stephanie, Aurelia
Cermin Dunia Kedokteran Vol 45, No 8 (2018): Alopesia
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (915.028 KB) | DOI: 10.55175/cdk.v45i8.623

Abstract

Rambut merupakan salah satu adneksa kulit yang terdapat di seluruh tubuh, kecuali telapak tangan, telapak kaki, kuku, dan bibir. Folikel rambut memiliki fase pertumbuhan dan fase istirahat yang bervariasi tergantung usia dan tempat tumbuh serta faktor fisiologis dan patologis. Alopesia androgenetik termasuk salah satu kelainan rambut yang disebabkan oleh faktor genetik dan hormon androgen ekstragonadal di kulit kepala. Alopesia androgenetik sering menyebabkan tekanan psikologis dan menurunnya kualitas hidup.Hair is one of the adnexa of skin in all body parts except palm, soles, nails, and lip. Hair follicle undergoes growing phase and resting phase in variable periods of time depending on age, body site, physiological and pathological factors. Androgenetic alopecia is one of hair disorders caused by genetic factor and extragonadal androgenic hormone in the scalp. Androgenetic alopecia often causes significant psychological distress and reduction of quality of life.
Masalah Virus Zika pada Kehamilan Richard, Timoteus; Kristanto, Andi; Adiwinata, Randy; Stephanie, Aurelia; Christianty, Finna; Belinda Phang, Beatrice; Adiwinata, Sheila
Cermin Dunia Kedokteran Vol 43, No 5 (2016): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.895 KB) | DOI: 10.55175/cdk.v43i5.57

Abstract

Wabah Virus Zika (ZIKV) merebak pada tahun 2015 hingga 2016 terutama di benua Amerika dan mendapat perhatian dunia. ZIKV merupakan penyakit yang ditularkan oleh nyamuk Aedes, umumnya self limiting dan jarang fatal pada dewasa. Perhatian lebih kepada ibu hamil karena potensi janin mikrosefalus. Centers for Disease Control and Prevention (CDC) telah mengeluarkan beberapa rekomendasi diagnosis dan manajemen ZIKV baik pada ibu hamil maupun pada bayi baru lahir. Pencegahan dan diagnosis dini ZIKV menjadi kunci utama penanganan.
Sindrom Stevens-Johnson Diduga Akibat Fenitoin Stephanie, Aurelia; Susilowati, Eny
Cermin Dunia Kedokteran Vol 45, No 4 (2018): Cidera Kepala
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (163.59 KB) | DOI: 10.55175/cdk.v45i4.666

Abstract

Sindrom Stevens-Johnson (SSJ) merupakan bagian dari nekrolisis epidermis (NE) yaitu sindrom reaksi mukokutan akut yang ditandai dengan nekrosis dan pengelupasan epidermis yang luas. Diaporkan seorang perempuan, usia 21 tahun, datang ke UGD rumah sakit dengan keluhan demam dan timbul ruam-ruam merah yang kemudian berisi air sejak 3 hari. Setelah konsumsi fenitoin, timbul bercak merah disertai gatal di daerah paha, tungkai dan punggung. Dua hari kemudian bercak merah tersebut mulai berisi cairan berdinding kendur dan menyebar ke seluruh tubuh. Pada hari ke-9 perawatan, pasien mengalami perbaikan klinis dan boleh pulang.Stevens-Johnson Syndrome (SJS) is a type of epidermal necrolysis (NE) , a syndrome of acute mucocutaneus reaction recognized by widespread necrosis and epidermal lysis. A case of 21 year-old female, presented in emergency with fever and reddish rash followed by vesicles since 3 days. After phenytoin consumption, reddish spots with urticaria were observed in thigh, legs and back. Two days later, they were followed with vesicles spreading to whole body. Clinical improvement was observed after 9 days, and the patient was discharged.
Keloid Daun Telinga (Ear Lobe Keloid) Stephanie, Aurelia; Susilowaty, Eny
Cermin Dunia Kedokteran Vol 44, No 6 (2017): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.879 KB) | DOI: 10.55175/cdk.v44i6.768

Abstract

Telinga merupakan salah satu organ tubuh yang paling sering ditindik. Efek samping tindik telinga antara lain keloid. Umumnya keloid timbul sekitar 3 minggu hingga tahunan setelah luka dan tidak hilang spontan. Selain keluhan kosmetik, keloid juga dapat menimbulkan rasa kebas, gatal, nyeri. Keloid stadium dini sulit dibedakan dari skar hipertrofi; skar hipertrofi regresi dalam 1-2 tahun, sedangkan keloid terus bertumbuh. Penanganan keloid di daun telinga lebih sulit dengan tingkat kegagalan dan rekurensi cukup tinggi.Auricle the most popular site of body piercing. Keloid is one of the side effect from ear piercing, usually appears after 3 weeks or even years and difficult to heal spontaneously. Besides cosmetic problem, several symptoms such as numb, itch, pain can arise. Early keloid and hypertrophic scar are difficult to be differentiated; hypertrophic scar will regress after 1-2 years, while keloid will grow continuously. Ear lobe keloid is more difficult to treat with high failure and recurrence rate. 
Nevus Unius Lateris (NUL) in a Theree-Year-Old Child Treated by Tretinoin 0.025%, Desoxymethasone 0.25%, and Urea 20% Cream Stephanie, Aurelia; Vibriyanti Karna, NLP Ratih; Karmila, IGAA Dwi; Laksmi, Hermina; Stella, Aurelia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.149-152

Abstract

Background: Linear verrucous epidermal nevus is the most frequent variant of the epidermal nevus classification. Linear verrucous epidermal nevus is characterized by the proliferation of epithelium arranged in a configuration that follows Blaschko's line. Nevus unius lateris (NUL) is a variant of the verrucous epidermal nevus, which has a unilateral distribution of lesions. Lesions are usually found at birth or in the first year of life as brown to grey verrucous papules or papillomatous plaques. The management of NUL is challenging as the results are varied and there is a high risk of recurrence. Purpose: to report a case of NUL and its management, especially in children. Case: A 3-year-old girl presented with brownish spots and multiple small lumps on the left buttock that have extended to the left leg since she was 9-days-old. On dermatologic examination, there were numerous hyperpigmented verrucous papules and plaques along the Blaschko line over the affected area. In this case, the diagnosis of NUL, is based on clinical symptoms and dermoscopy examination showed multiple large brown oval or round structures with hyperpigmented brown border. The patient was treated with combination topical therapy of tretinoin 0.025%, corticosteroid desoxymethasone 0.25%, and urea 20% cream, and the lesion improved within four weeks. Discussion: Epidermal nevus is often cosmetically disturbing. The treatment is still challenging and various, including surgical and non-surgical, but none is ideal and could potentially recur over months or years. dst. 
EKSISI KARSINOMA SEL BASAL TIPE CAMPURAN YANG DILAKUKAN PENUTUPAN DEFEK DENGAN FLAP RHOMBOID Stephanie, Aurelia; Winaya, Ketut Kwartantaya; Darmaputra, IGN; Laksmi, Hermina; Stella, Aurelia
Media Dermato-Venereologica Indonesiana Vol 52 No 1 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i1.248

Abstract

Pendahuluan: Karsinoma sel basal (KSB) merupakan jenis kanker kulit yang berasal dari sel yang tidak mengalami keratinisasi pada lapisan basal epidermis. Tumor ganas ini ditandai dengan pertumbuhan tumor yang lambat, jarang menimbulkan metastasis dan dapat menyebabkan destruksi jaringan sekitarnya. Dari semua jenis kanker kulit, KSB merupakan kanker kulit yang paling sering ditemukan di seluruh dunia termasuk Indonesia dengan insidensi yang bervariasi. Di RSUP Sanglah Denpasar pada bulan Januari 2018–Desember 2020 terdapat 18 kasus KSB. Kasus: Seorang perempuan berusia 51 tahun, suku Bali, Warga Negara Indonesia, muncul benjolan kehitaman di hidung sejak dua tahun yang lalu. Benjolan dirasakan membesar, terkadang berdarah jika terkena garukan atau gesekan. Riwayat sering terpajan sinar matahari selama 5 jam sehari. Diagnosis KSB ditegakkan berdasarkan anamnesis, gejala klinis, pemeriksaan dermoskopi dan histopatologi dengan gambaran bervariasi sesuai subtipe KSB. Diskusi: Tujuan utama penatalaksanaan pada KSB adalah untuk mengeradikasi tumor serta tetap mempertahankan fungsi organ dan kosmetik yang baik. Tata laksana pada pasien ini berupa bedah eksisi yang ditutup dengan rhomboid flap. Bedah eksisi merupakan modalitas pengobatan terbaik untuk karsinoma dan mencegah kekambuhan. Kesimpulan: Rhomboid flap merupakan salah satu desain transposisi berbentuk belah ketupat yang memiliki kelebihan berupa penyembuhan yang efektif dan hasil kosmetik yang baik karena jaringan parut yang minimal.
LAPORAN KASUS: ROSASEA TIPE PAPULOPUSTULAR YANG DITERAPI DOKSISIKLIN ORAL, ASAM AZALEAT DAN RETINOID TOPIKAL Stephanie, Aurelia; Kwartantaya, Ketut; Laksmi, Hermina; Stella, Aurelia
Media Dermato-Venereologica Indonesiana Vol 51 No 2 (2024): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v51i2.290

Abstract

ABSTRAK Rosasea merupakan suatu kondisi inflamasi kronis pada kulit bersifat kambuhan yang mengenai daerah sentrofasial (hidung, dagu, pipi, dahi dan glabela). Secara klinis, rosasea ditandai oleh adanya eritema (transien hingga persisten), telangiektasis, papul, pustul dan perubahan fimatosa. Tanda klinis tersebut disertai rasa gatal, terbakar, tersengat atau nyeri. Di RSUP Sanglah Denpasar sejak Januari 2019 sampai Desember 2021 tercatat sebanyak 5 kasus rosasea dengan tipe papulopustular. Laki-laki, usia 49 tahun, suku Jawa, Warga Negara Indonesia, muncul kemerahan pada kedua pipi, dagu, hidung dan dahi disertai benjolan kecil seperti jerawat berwarna kemerahan dan sebagian berisi nanah disertai rasa nyeri seperti terbakar dan gatal sejak 2 tahun yang lalu. Riwayat sering terpajan sinar matahari. Pasien mengaku gemar makan makanan pedas, berkuah panas seperti sup atau soto, serta meminum kopi panas setiap pagi. Diagnosis rosasea ditegakkan berdasarkan anamnesis, gejala klinis, pemeriksaan dermoskopi dan histopatologi. Tatalaksana berupa doksisiklin 100 mg tiap 12 jam intra oral, asam azaleat 20% gel topikal tiap 24 jam (pagi hari), tabir surya topikal dengan Sun Protector Factor (SPF) 45, tretinoin 0,025% krim topikal tiap 24 jam memberikan perbaikan klinis pada minggu ketujuh. Terapi yang tepat dan menghindari faktor pencetus umumnya dapat mengurangi kekambuhan rosasea. Kata kunci: eritema, inflamasi, papulopustular, rosasea, telangiektasis
Co-Authors Adiwinata, Sheila Andi Kristanto aryani, Inda astri Belinda Phang, Beatrice Daryago, Adi Agung Anantawijaya Diba, Sarah Finna Christianty, Finna Fitriani Fitriani I Gusti Ayu Agung Dwi Karmila I Gusti Nyoman Darmaputra Kartowigno, Soenarto Kwartantaya, Ketut Laksmi, Hermina Luh Made Mas Rusyati Prima Saraswati Sanjiwani Sudarsa Randy Adiwinata, Randy Stella, Aurelia Susilowati, Eny Susilowaty, Eny Timoteus Richard, Timoteus Vibriyanti Karna, NLP Ratih Winaya, Ketut Kwartantaya Yulia Farida Yahya