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Antibacterial potential of celery leaf extract toothpaste on the growth of Streptococcus mutans ATCC 25175 Hayati, Maulida; Mailiza, Fitria; Savitri, Shifa Khumaira
Padjadjaran Journal of Dentistry Vol 35, No 1 (2023): March 2023
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no1.30624

Abstract

ABSTRACTIntroduction: Celery (Apium graveolens L.) is a member of the Apiaceae family that can grow everywhere. Celery contains flavonoids, saponins, tannins, essential oils, apigenin, choline, vitamins A, B, C, asparagine bitter substances. Celery contains flavonoids, saponins, and tannins which are antibacterial compounds. Streptococcus mutans is a Gram-positive bacterium creating an acidic atmosphere in the oral cavity, which causes insufficient saliva to prevent enamel demineralisation which can lead to dental caries. The purpose of this study was to analyze the inhibition effect of celery leaf extract (Apium graveolens L.) on the growth of Streptococcus mutans. Methods: This   type   of experimental laboratory research uses the Post Test Only Control Group Design. The samples were Apium graveolens L. and Streptococcus mutans ATCC 25175. The number of treatment groups was 24 with concentrations of 20, 40, 60, and 80%. Toothpaste containing antibacterial ingredients was used as positive control and for negative control, a basic toothpaste formula without antibacterial ingredients, namely carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test with normality test using Shapiro-Wilk and homogeneity test using Levene test. The results at a concentration of 20, 40, 60 and 80% with a positive control there was no significant difference because the sig value was >0.05. Results: The results showed that Celery containing toothpaste inhibits Streptococcus mutans growth (p value <0.05) that there is a significant inhibition effect of Apium graveolens L. extract toothpaste on the growth of Streptococcus mutans. Conclusion: There is an inhibition effect of celery leaf (Apium graveolens L.) extract toothpaste on the growth of Streptococcus mutans.Keywords: streptococcus mutans ATCC 25175, inhibition, toothpaste, celery, apium graveolens L
Uji zona hambat ekstrak metanol teripang pandan (Stichopus variegatus semper) terhadap bakteri Porphyromonas gingivalis Arma, Utmi; Mailiza, Fitria; Anggestia, Wulan; Azira, Faiza Nur
MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Vol 10, No 1 (2024)
Publisher : Fakultas Kedokteran Gigi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mkgk.93476

Abstract

Oral Squamous Cell Carcinoma (OSCC) adalah jenis kanker yang berasal dari sel epitel skuamosa di mukosa yang seringkali bersifat infiltratif dan metastatik. OSCC dapat terjadi di semua bagian rongga mulut. Etiologi OSCC belum diketahui secara pasti, namun terdapat faktor predisposisi seperti infeksi bakteri, salah satunya adalah Porphyromonas gingivalis. Porphyromonas gingivalis adalah bakteri normal di rongga mulut yang berperan dalam berbagai penyakit, seperti karsinoma dan penyakit periodontal. Pengobatan OSCC sangat bervariasi, termasuk pengobatan herbal yang menggunakan hewan. Salah satu hewan yang sering digunakan dalam pengobatan herbal adalah Stichopus variegatus semper atau teripang pandan. Teripang pandan mengandung senyawa aktif yang dapat berfungsi sebagai agen antikanker. Tujuan dari penelitian ini adalah untuk menentukan zona hambat ekstrak metanol dari teripang pandan terhadap Porphyromonas gingivalis. Jenis penelitian ini adalah eksperimen laboratoris dengan desain penelitian Post test only control group. Metode yang digunakan dalam penelitian ini adalah disk difusi dengan 5 perlakuan dan 5 ulangan menggunakan konsentrasi 5%, 6%, 7%, serta kontrol positif dan kontrol negatif, yang dianalisis dengan uji One Way Anova. Hasil yang diperoleh menunjukkan adanya zona hambat ekstrak metanol dari teripang pandan terhadap bakteri Porphyromonas gingivalis dengan nilai p < 0.05. Kesimpulan dari penelitian ini adalah bahwa ekstrak metanol dari teripang pandan mampu menghambat pertumbuhan dan perkembangan bakteri Porphyromonas gingivalis, dengan ekstrak terbaik pada konsentrasi 7% yang tergolong moderat.
Peningkatan Pengetahuan dan Keterampilan Orang Tua dalam Deteksi Dini Masalah Kesgilut pada Anak Disabilitas: Improving Parents' Knowledge and Skills in Early Detection of Oral Health Problems among Children with Disabilities Ningrum, Valendriyani; Bakar, Abu; Mahata, Intan Batura Endo; Mailiza, Fitria; Femilian, Afyla; Ananda, Ricki
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 1 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i1.8396

Abstract

Oral health problems are more vulnerable in children with disabilities than children in general. One of the efforts to minimize these problems is to increase parents' awareness of the importance of maintaining effective oral health in children with disabilities. Therefore, it is necessary to increase the knowledge and skills of parents who have children with disabilities in the early detection of oral health problems so that severity does not occur. This community service program is in the form of socialization activities and early detection skills training conducted for 71 parents/caregivers on 20 September 2024 at the RSGMP Baiturrahmah Hall, Padang City. Pre and post-assessment of parents' knowledge and skills were conducted, out of 72 parents/caregivers only 39 parents/caregivers completed the pre and post-test. The results of the analysis of existing data showed a significant increase in both the knowledge and skills of parents in the early detection of oral health problems. This activity needs to be carried out regularly as a promotional effort to improve the degree of oral health in children with disabilities.
Inhibition test of noni fruit extract (Morinda citrifolia L.) against Candida albicans growth: Uji daya hambat ekstrak buah mengkudu (Morinda citrifolia L.) terhadap pertumbuhan Candida albicans Munov, Aqilla Patricia; Mailiza, Fitria; Kornialia
Makassar Dental Journal Vol. 14 No. 2 (2025): Volume 14 Issue 2 August 2025
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v14i2.1240

Abstract

Candidiasis is a fungal infection caused by overgrowth of Candida albicans species. Noni fruit (Morinda citrifolia L.) is one of the plants that has antifungal activity through the content of compounds such as flavonoids, saponins, alkaloids, terpenoids, pheno-lics, and tannins. This study discusses the inhibition of noni fruit extract (NFE) at concentrations of 10%, 15%, and 20% against the growth of C.albicans using laboratory experimental methods with a descriptive approach and using a one shot case study de-sign. Noni fruit was extracted using maceration method with 96% methanol solvent. A total of 18 samples of C.albicans were divi-ded into 3 treatments, namely 10%, 15% and 20% concentrations. The inhibition test was carried out using the pitting diffusion me-thod, while the measurement of the inhibition zone using a caliper showed that 10% NFE had an inhibition that was categorised as moderate, 15% was categorised as strong, and 20% was also categorised as strong. It was concluded that noni fruit extract has inhibitory power against the growth of C.albicans, with the best effectiveness at a concentration of 20% which showed a strong inhibition category.