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All Journal Best Journal (Biology Education, Sains and Technology) Jurnal Penelitian Farmasi dan Herbal Jurnal Pengabdian Masyarakat Putri Hijau
Sanjaya, Angga Nugraha
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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SOSIALISASI PENTINGNYA MENGETAHUI BAHAYA HIDROKUINON PADA SKINCARE DAN KOSMETIK DI SMK 8 MUHAMMADIYAH MEDAN SELAYANG Simorangkir, Delisma; Puspita, Rika; Sanjaya, Angga Nugraha; Lestari, Puji
Jurnal Pengabdian Masyarakat Putri Hijau Vol 4 No 3 (2024): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v4i3.1849

Abstract

The modern era has very minimal information about juvenile cosmetics that involve risks associated with hazardous or illegal products. The choice and application of cosmetics has not been taught to SMK Muhammadiyah 8 Medan students. The explanation should help students understand how important it is to select safe care products for young children to utilize. The topics covered in the discussion included a variety of cosmetic chemicals, the significance of understanding how hydroquinon affects cosmetics and goods, and tips for selecting skincare products according to skin type. The results of Volunteers found that most teenagers had oily skin (38.09%), with some experiencing skin problems (79.37%). Acne is the most common problem (42.68%), and 79.37% have used face care. After receiving the material, participants scored 88.57, indicating their knowledge. The examination was declared successful because the participants understood the material.
UJI AKTIVITAS ANTIBAKTERI FORMULASI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN PALA (Myristica fragrans Houtt) TERHADAP BAKTERI Staphylococcus epidermidis DAN Streptococcus sp Sanjaya, Angga Nugraha; Sari, Tio Ranti
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2258

Abstract

The pala leaves contain alkaloids, flavonoids, saponins, tannins, and steroids which high antiseptic and antibacterial effects. The goal of the research make a formulation of hand sanitizer gel with etanol extreact by pala leaves (Myristica fragrans Houtt) as the antibacterial againt the Staphylococcus epidermidis and Streptococcus sp bacteria with CMC-Na base. Pala leaves hand sanitizer gel with etanol extract was formulation I 5%, formulation II 10%, and formulation III 15%. The method used in this study was antibacterial testing method used is the disc diffusion technique. Hand sanitizer gel is tested for the physical properties including organoleptic test, pH test, homogeneity test, and spreadability test. Hand sanitizer gel which has antibacterial activity against the Staphylococcus epidermidis and Streptococcus sp, bacteria is second (III) formulation in with concentration 15% that has an inhibition zone of 17 mm on bacteria Staphylococcus epidermidis and 16,86 mm on bacteria Streptococcus sp, mean while in formulation II with concentration 10% that has an inhibition zone of 13,16 mm on bacteria Staphylococcus epidermidis ang 13,16 on bacteria Streptococcus sp, mean while in formulation I with concentration 5% that has an inhibition zone of 12,02 mm on bacteria Staphylococcus epidermidis and 12,16 mm on bacteria Streptococcus sp, and the last positive control (nuvo gel hand sanitizer) that has an inhibition 17,73 mm on bacteria Stahylococcus epidermidis and 17,69 mm on bacteria Streptococcus sp. The final results of the research indicate, there is an ability of hand sanitizer gel pala leaves (Myristica fragrans Houtt) extract to prevent the growth of Staphylococcus epidermidis and Streptococcus sp bacteria with concentration of 15% hand sanitizer gel preparation.
UJI EFEKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL RIMPANG JAHE (Zingiber officinale Roscoe) PADA TIKUS PUTIH JANTAN Manullang, Hengki Frengki; Sanjaya, Angga Nugraha; Angelina, Tresia
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12255

Abstract

Peradangan merupakan respons biologis alami tubuh terhadap cedera atau infeksi, yang ditandai dengan gejala seperti nyeri, panas, kemerahan, dan pembengkakan. Penggunaan obat antiinflamasi sintetis jangka panjang seringkali menimbulkan efek samping, terutama pada sistem pencernaan dan kardiovaskular. Salah satu alternatif potensial adalah penggunaan tanaman obat, seperti rimpang jahe (Zingiber officinale Roscoe), yang mengandung senyawa aktif termasuk flavonoid, alkaloid, dan gingerol, yang dikenal karena sifat antiinflamasinya. Penelitian ini bertujuan untuk mengevaluasi efektivitas ekstrak etanol 96% rimpang jahe dalam mengurangi peradangan yang diinduksi karagenan pada tikus putih jantan (Rattus norvegicus L.). Metode eksperimental dengan rancangan acak lengkap digunakan. Subjek dibagi menjadi lima kelompok: kelompok kontrol negatif (1% Na CMC), kelompok kontrol positif (natrium diklofenak), dan tiga kelompok perlakuan yang menerima ekstrak jahe dengan dosis 300, 400, dan 500 mg/kgBB. Data dianalisis menggunakan ANOVA Satu Arah dan dilanjutkan dengan uji post-hoc Tukey HSD. Semua kelompok perlakuan menunjukkan penurunan tingkat inflamasi, dengan dosis 500 mg/kgBB menunjukkan efek paling signifikan, sangat mirip dengan efek natrium diklofenak. Uji statistik menunjukkan perbedaan yang signifikan antara kelompok kontrol negatif dan kelompok perlakuan. Ekstrak etanol rimpang jahe menunjukkan potensi sebagai agen antiinflamasi alami yang efektif, terutama pada dosis 500 mg/kgBB
Co-Authors Angelina, Tresia Delisma Marsauli Simorangkir Hengki Frengki Manullang, Hengki Frengki PUJI LESTARI Puspita, Rika sari, tio ranti