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All Journal Best Journal (Biology Education, Sains and Technology) Jurnal Penelitian Farmasi dan Herbal International Journal Of Science, Technology & Management (IJSTM) Jurnal Pengabdian Masyarakat Putri Hijau PCJN Pharmaceutical and Clinical Journal of Nusantara
Sanjaya, Angga Nugraha
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SOSIALISASI PENTINGNYA MENGETAHUI BAHAYA HIDROKUINON PADA SKINCARE DAN KOSMETIK DI SMK 8 MUHAMMADIYAH MEDAN SELAYANG Simorangkir, Delisma; Puspita, Rika; Sanjaya, Angga Nugraha; Lestari, Puji
Jurnal Pengabdian Masyarakat Putri Hijau Vol 4 No 3 (2024): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v4i3.1849

Abstract

The modern era has very minimal information about juvenile cosmetics that involve risks associated with hazardous or illegal products. The choice and application of cosmetics has not been taught to SMK Muhammadiyah 8 Medan students. The explanation should help students understand how important it is to select safe care products for young children to utilize. The topics covered in the discussion included a variety of cosmetic chemicals, the significance of understanding how hydroquinon affects cosmetics and goods, and tips for selecting skincare products according to skin type. The results of Volunteers found that most teenagers had oily skin (38.09%), with some experiencing skin problems (79.37%). Acne is the most common problem (42.68%), and 79.37% have used face care. After receiving the material, participants scored 88.57, indicating their knowledge. The examination was declared successful because the participants understood the material.
UJI AKTIVITAS ANTIBAKTERI FORMULASI SEDIAAN GEL HAND SANITIZER EKSTRAK ETANOL DAUN PALA (Myristica fragrans Houtt) TERHADAP BAKTERI Staphylococcus epidermidis DAN Streptococcus sp Sanjaya, Angga Nugraha; Sari, Tio Ranti
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 2 (2025): Jurnal Penelitian Farmasi Dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i2.2258

Abstract

The pala leaves contain alkaloids, flavonoids, saponins, tannins, and steroids which high antiseptic and antibacterial effects. The goal of the research make a formulation of hand sanitizer gel with etanol extreact by pala leaves (Myristica fragrans Houtt) as the antibacterial againt the Staphylococcus epidermidis and Streptococcus sp bacteria with CMC-Na base. Pala leaves hand sanitizer gel with etanol extract was formulation I 5%, formulation II 10%, and formulation III 15%. The method used in this study was antibacterial testing method used is the disc diffusion technique. Hand sanitizer gel is tested for the physical properties including organoleptic test, pH test, homogeneity test, and spreadability test. Hand sanitizer gel which has antibacterial activity against the Staphylococcus epidermidis and Streptococcus sp, bacteria is second (III) formulation in with concentration 15% that has an inhibition zone of 17 mm on bacteria Staphylococcus epidermidis and 16,86 mm on bacteria Streptococcus sp, mean while in formulation II with concentration 10% that has an inhibition zone of 13,16 mm on bacteria Staphylococcus epidermidis ang 13,16 on bacteria Streptococcus sp, mean while in formulation I with concentration 5% that has an inhibition zone of 12,02 mm on bacteria Staphylococcus epidermidis and 12,16 mm on bacteria Streptococcus sp, and the last positive control (nuvo gel hand sanitizer) that has an inhibition 17,73 mm on bacteria Stahylococcus epidermidis and 17,69 mm on bacteria Streptococcus sp. The final results of the research indicate, there is an ability of hand sanitizer gel pala leaves (Myristica fragrans Houtt) extract to prevent the growth of Staphylococcus epidermidis and Streptococcus sp bacteria with concentration of 15% hand sanitizer gel preparation.
UJI EFEKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL RIMPANG JAHE (Zingiber officinale Roscoe) PADA TIKUS PUTIH JANTAN Manullang, Hengki Frengki; Sanjaya, Angga Nugraha; Angelina, Tresia
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12255

Abstract

Peradangan merupakan respons biologis alami tubuh terhadap cedera atau infeksi, yang ditandai dengan gejala seperti nyeri, panas, kemerahan, dan pembengkakan. Penggunaan obat antiinflamasi sintetis jangka panjang seringkali menimbulkan efek samping, terutama pada sistem pencernaan dan kardiovaskular. Salah satu alternatif potensial adalah penggunaan tanaman obat, seperti rimpang jahe (Zingiber officinale Roscoe), yang mengandung senyawa aktif termasuk flavonoid, alkaloid, dan gingerol, yang dikenal karena sifat antiinflamasinya. Penelitian ini bertujuan untuk mengevaluasi efektivitas ekstrak etanol 96% rimpang jahe dalam mengurangi peradangan yang diinduksi karagenan pada tikus putih jantan (Rattus norvegicus L.). Metode eksperimental dengan rancangan acak lengkap digunakan. Subjek dibagi menjadi lima kelompok: kelompok kontrol negatif (1% Na CMC), kelompok kontrol positif (natrium diklofenak), dan tiga kelompok perlakuan yang menerima ekstrak jahe dengan dosis 300, 400, dan 500 mg/kgBB. Data dianalisis menggunakan ANOVA Satu Arah dan dilanjutkan dengan uji post-hoc Tukey HSD. Semua kelompok perlakuan menunjukkan penurunan tingkat inflamasi, dengan dosis 500 mg/kgBB menunjukkan efek paling signifikan, sangat mirip dengan efek natrium diklofenak. Uji statistik menunjukkan perbedaan yang signifikan antara kelompok kontrol negatif dan kelompok perlakuan. Ekstrak etanol rimpang jahe menunjukkan potensi sebagai agen antiinflamasi alami yang efektif, terutama pada dosis 500 mg/kgBB
Phytochemical Screening and Antibacterial Potential Ethanol Extract of Kemangi Leaves (Ocimum basilicum L.) Towards Staphylococcus aureus Sanjaya, Angga Nugraha; Harahap, Urip; Dalimunthe, Aminah
International Journal of Science, Technology & Management Vol. 3 No. 6 (2022): November 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i6.630

Abstract

An infectious disease is a disease with the highest prevalence in the world, with a great risk of transmission. Staphylococcus aureus is a pathogen that can cause several infectious diseases. The use of kemangi leaves as vegetables can be used as an invention in treating infections caused by bacteria. The purpose of this study was a phytochemical screening test to determine what metabolites are contained and their potential activity against Staphylococcus aureus. The research method is to carry out a qualitative phytochemical screening test using reagents and an antibacterial potential test against Staphylococcus aureus using the Kirby-Bauer method (diffusion agar) with varying concentrations. The results showed that kemangi leaves extract showed positive results on the secondary metabolite compounds, were alkaloids, flavonoids, saponins, tannins, glycosides, and steroids/triterpenoids. The diameter of the inhibition zone at a concentration of 500 mg/mL showed the diameter of the inhibition zone was 11.93 ± 0.25 mm with the strong category group. The conclusion is that the ethanolic extract of kemangi leaves shows the ethanolic extract of kemangi leaves has potential as an antibacterial.
TESTING THE EFFECTIVENESS OF BIDARA LEAF ETHANOL EXTRACT (Ziziphus mauritiana L.) IN GEL PREPARATIONS FOR BURN WOUNDS IN MALE RABBIT (Oryctolapus cuniculus) Sulasmi, Sulasmi; Sanjaya, Angga Nugraha; Bangun, Sofia Elia Sari; Cahaya, Cucu Arum Dwi
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.99 KB) | DOI: 10.58549/pcjn.v1i01.2

Abstract

Abstract Bidara plants have many benefits in the treatment of sore skin, ulcers, and burns. Burns are a form of tissue damage or loss caused by contact with a heat source such as fire, hot water, electricity, radiation, or corrosive substances. This study aims to determine the effectiveness of the ethanol extract of bidara leaf in healing burns in male rabbits compared to bioplacenta. This study used an experimental method of maceration extraction using 96% ethanol. To test the effect of burns, 15 test animals were grouped into five groups, each of which used three test animals. The treatment group was a gel-based negative control group, a positive bioplacenta control group, and a treatment group with bidara leaf ethanol extract at concentrations of 5%, 10%, and 15%. The results of the research on the effectiveness of healing burns in the three formulations, namely a concentration of 15%, showed faster healing of wound diameter in male rabbits compared to concentrations of 5% and 10% but were not more effective when compared to bioplacenta ointment. Keywords: Bidara leaf ethanol extract, burns, ointment and bioplacenton
Co-Authors Aminah Dalimunthe Angelina, Tresia Bangun, Sofia Elia Sari Cahaya, Cucu Arum Dwi Delisma Marsauli Simorangkir Hengki Frengki Manullang, Hengki Frengki PUJI LESTARI Puspita, Rika sari, tio ranti Sulasmi Sulasmi Urip Harahap