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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Respirologi Indonesia Jurnal Penyakit Dalam Indonesia
Fitrina, Dewi Wahyu
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Rasio Neutrofil Limfosit dan Kadar D-Dimer berdasarkan Derajat Keparahan Pasien COVID-19 di Rumah Sakit Semen Padang : Studi Kasus Kontrol Besri, Hanifa Zahra; Efrida, Efrida; Jurnalis, Yusri Dianne; Putra, Andani Eka; Fitrina, Dewi Wahyu; Husni, Husni
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 2
Publisher : UI Scholars Hub

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Abstract

Introduction. Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) which in 2020 was declared a global pandemic. In the management of COVID-19, patients are classified according to the severity. Identifying prognostic factors at an early stage helps assess severity risks. Abnormal hematological parameters were present in COVID-19 patients such as the elevation of neutrophil lymphocyte ratio (NLR) and D-dimer patients. This study aimed to determine the NLR and D-dimer levels based on the severity of COVID-19 patients. Methods. This study was an observational analytical study that used a case-control approach using 100 medical records of COVID-19 patients who were treated at Semen Padang Hospital in 2021. Consecutive sampling was used in this study. ANOVA test and the Kruskal-Wallis test were used for bivariate analysis. The results were considered significant if the p-value <0.05. Results. Characteristics of patients treated for COVID-19 were: 51% male and 49% female, mean age 57.79 (SD 13.5) years. NLR values based on the severity (mild, moderate, severe, and critical) were 3.12 (SD 2.04), 3.51 (SD 2.87), 6.89 (SD 3.6), 12.57 (SD 10.34) respectively; p<0.05. The median value of D-dimer (ng/mL) based on the severity (mild, moderate, severe, and critical) were 444, 791, 1,610, 2,135; p<0.05. The results of this study showed that there were significant differences in the NLR values and D-dimer levels based on severity. Conclusion. RNL value and D-dimer levels increase the most in the critical degree group and shows a significant relationship in COVID-19 patients.
Pleural Amebiasis without Hepar Involvement Handayani, Friska; Medison, Irvan; Fitrina, Dewi Wahyu; Mizarti, Dessy
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 2 (2023): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.2.2023.229-238

Abstract

Background:  Pleuropulmonary amebiasis is the most common complication of amoebic liver abscess, occurring in 15% of patients with amoebic liver disease and in 1% of patients with amoebic dysentery. Most commonly occurs by direct extension of a right superior lobe hepatic abscess through the diaphragm to the right lower lobe of the lung with a mortality rate of 5-16%. Primary pleural amebiasis without liver involvement is rare.Case Presentation: Reported an 18-year-old male patient with pleural amebiasis from the results of parasitological examination of pleural fluid found Entamoeba histolytica. History, physical examination and support showed normal liver function. The patient has a history of poor sanitation with a dissertation of unhygienic habits. Patients without liver problems remain at risk for amoebiasis pleuraConclusion: Pleural amebiasis without liver involvement was a rare case. Further investigation was needed in patients with pleural amoebiasis to other organs, such as the liver and digestive tract. Diagnose pleural amebiasis should be the main focus in determining the etiology. Entamoeba histolytica may be involved in pleural inflammation and cause effusion.
Co-Existence of Tuberculosis and Lung Cancer Aribowo, Kornelis; Medison, Irvan; Mizarti, Dessy; Fitrina, Dewi Wahyu
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 1 (2022): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.1.2022.51-61

Abstract

Background: Tuberculosis (TB) and lung cancer cause significant morbidity and mortality worldwide and pose a global health threat. Each year these two diseases account for more than 1.6 million deaths worldwide. The incidence of both diseases is still high in many developing countries, especially in Asian countries. TB and lung cancer are often confused and misdiagnosed, especially in countries with diagnostic challenges of low TB incidence and risk of missed diagnosis.Case Presentation: The following is a case report of a 53-year-old male patient diagnosed with pulmonary TB accompanied by right lung cancer, and the same respiratory complaints can be had by lung cancer and TB. However, the presence of facial edema (part of the superior vena cava syndrome) causes clinicians to focus more on lung cancer so that the diagnosis of TB is often overlooked.Conclusion: Tuberculosis should be a significant concern, especially in patients with malignancies such as lung cancer and located in TB endemic areas. Delay in diagnosis and or miss diagnosis will affect the patient's outcome.
Association Between the Severity of Chronic Obstructive Pulmonary Disease and the Probability of Pulmonary Hypertension In a Tertiary Hospital Handayani, Friska; Herman, Deddy; Fitrina, Dewi Wahyu
Jurnal Respirologi Indonesia Vol 45 No 2 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i2.873

Abstract

Background: Chronic obstructive pulmonary disease (COPD) patients with pulmonary hypertension (PH) have a poor prognosis, which worries doctors. The prevalence of COPD-related PH is unclear. The lack of anatomical criteria for right ventricular hypertrophy may explain research variance. Only type 1 PH patients undergo direct right cardiac catheterization of pulmonary artery pressure. Methods: A cross-sectional analytical descriptive study examined stable COPD patients visiting the pulmonary department at M. Djamil Hospital, Padang, from November 2023 to February 2024 for PH probability. Results: This study included 64 participants, with a majority aged between 40 and 65 years (59.4%), a significant proportion male (82.8%), and a junior high school (29.7%) level of education. Most of the subjects smoked (81.2%), had severe Brinkman Index (75.0%), had severe GOLD criteria (50.0%), and had no comorbidities (53.1%). No correlation was found between the severity of COPD and the likelihood of PH (P=0.591). The Brinkman Index of smokers was a significant risk factor for PH (P=0.010; OR=1.282; 95% CI=0.260-6.315).  Conclusion: There is no significant association between the severity of COPD according to GOLD criteria and the likelihood of PH.
Co-Authors Andani Eka Putra aribowo, kornelis Besri, Hanifa Zahra Efrida Efrida Handayani, Friska Herman, Deddy Husni Husni Irvan Medison Mizarti, Dessy Yusri Dianne Jurnalis