Article Per Year (5 Year)
p-Index From 2020 - 2025
1.037
P-Index
This Author published in this journals
All Journal JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Indah Sains dan Klinis
Ernawaty Ginting
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Efek Antihiperlipidemia Kombucha Daun Kari (Murraya koenigii (L.) Spreng) pada Tikus Putih Jantan (Rattus norvegicus) yang Diinduksi Dengan High Fat dan PTU Hardyanto Napitupulu,; Muharni Saputri; Salmah Handayani Lubis; Muflihah Fujiko; Ernawaty Ginting
Jurnal Indah Sains dan Klinis Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/7xzsgc35

Abstract

Curry leaves (Murraya koenigii (L.) Spreng) is a plant that is often used in cooking spices that are high in fat because curry leaves contain secondary metabolite compounds such asalkaloids, glycosides, and flavonoids that serve to inhibit the growth of free radicals and lower cholesterol levels. Generally curry leaves are processed traditionally in a simple form, while research will process curry leaves in the form of fermented beverages in the form of kombucha tea. This study aims to explore the process of making curry leaf kombucha tea and know the antihiperlipidemia effect. This research is descriptive and experimental, including material collection, simplisia making, phytochemical screening, fermentation of curry leaf kombucha, evaluation of dosage quality, testing of triglyceride levels in rats with Electrode-Based Biosensor technique. The mice used in this study were 25 and divided into 5 test groups. K1 (negative blank), K2 (Simvastatin), K3 (dose 100 ml), K4 (dose 150 ml), K5 (dose 200 ml) induced using 80% egg yolk and PTU 0.2%. The results showed that the quality evaluation of kombucha tea gave good results to pH 3.08-3.44 and did not experience changes in taste and smell. In the group of 5 doses of 200 ml with kombucha tea administration on the 7th to 15th day, it was shown that cholesterol levels decreased from 253.0 mg/dL to 92.2 ml/dL where these results were close to comparing (simvastatin) from 247.8 mg/dL to 79.2 mg/dL
Penetapan Kadar Formalin Pada Mie Basah Yang Beredar Di Pasar Peunayong Kota Banda Aceh Secara Spektrofotometri Visible Syarifah Nadia; Debi Meilani; Dea Anggreini; Siti Rahmi Ningrum; Supran Hidayat Sihotang; Ernawaty Ginting
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6296

Abstract

Formalin is a 37% formaldehyde solution in water, commonly misused as a food preservative despite its toxicity and prohibition in food products. This study aimed to determine the presence and levels of formalin in wet noodles sold at Peunayong Market, Banda Aceh, using visible spectrophotometry. A descriptive design was applied to three randomly selected samples. Qualitative tests using multiple reagents (Schiff, Schryver, KMnO₄, and a test kit) showed negative results for formalin presence. However, quantitative analysis with Spectroquant Prove 300 revealed that all samples contained formalin levels exceeding the acceptable standard. The concentrations ranged from 0.7433 mg/L to 0.8766 mg/L, indicating that the products are unsafe for consumption. These findings underline the need for stricter monitoring and improved food safety awareness among producers and consumers in traditional markets.
PENGARUH POLIMER KITOSAN DAN POLIVINIL ALKOHOL TAUT SILANG NATRIUM TRIPOLI FOSFAT TERHADAP KARAKTER PENETRASI FILM NATRIUM DIKLOFENAK Ernawaty Ginting; Robiatun Rambe
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 3 No. 2 (2020): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.176 KB) | DOI: 10.52943/jifarmasi.v3i2.397

Abstract

Background: Diclofenac sodium is a non-steroidal anti-inflammatory drug which has anti-inflammatory and pain effects. Transdermal administration of diclofenac sodium can control the release of diclofenac sodium from its base, which is expected to avoid side effects in the stomach and first pass metabolism in the liver. Objective: This study aims to determine the effect of chitosan polymers and polyvinyl alcohol crosslinked sodium tripoli phosphate on the penetration character of diclofenac sodium film. Method: Transdermal film is made by mixing chitosan solution and polyvinyl alcohol solution with the addition of glycerin and sodium diclofenac until the film is formed and then dried. Drop the sodium tripoli phosphate solution until a crosslink reaction occurs, then dried. Transdermal films were made in six formulas using chitosan (2%), polyvinyl alcohol (8%) with a ratio of 30:70 adding sodium tripolyphosphate solution at 10 minutes crosslink time (F1) and 20 minutes (F2), 50:50 crosslink time 10 minutes (F3) and 20 minutes (F4), 70:30 cross time 10 minutes (F5) and 20 minutes (F6). Evaluation of film character includes organoleptic observation, weight test, thickness, moisture content (%), interactions between ingredients, levels of active substances. Drug release was determined using Franz diffusion cells in phosphate buffer (pH7.4). All transdermal films meet the test requirements for uniformity in weight, thickness and moisture content. Penetration test in vitro film shows the formulation with 10 minutes crosslink time has cumulative percent and release flux is better than 20 minutes crosslink time. The release of dicofofen sodium transdermal film follows the release of a zero order erosion mechanism. FTIR examination showed no interaction between sodium diclofenac and excipients. Conclusion: Chitosan polymer, polyvinyl alcohol and sodium tripoli phosphate affect organoleptic properties and penetration through the skin. Transdermal film making with a 10 minute crosslink time results in a better release profile than a 20 minute crosslink time. Keywords: diclofenac sodium, chitosan, polyvinyl alcohol, sodium tripoli phosphate, glycerin, release kinetics.
Co-Authors Dea Anggreini Debi Meilani Hardyanto Napitupulu, Khalisa Khalisa Muflihah Fujiko Muharni Saputri Nilsya Febrika Zebua, Nilsya Febrika Rina Ridara Robiatun Rambe Salmah Handayani Lubis Siti Rahmi Ningrum Supran Hidayat Sihotang Syarifah Nadia