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All Journal Dental Journal (Majalah Kedokteran Gigi) MEDIC MEdical Dedication Cermin Dunia Kedokteran
Kristiyanto, Haryo Dimasto
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Dentistry Health Professions Medicine & Pharmacology Nursing Physics Public Health

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MEDICAL EMERGENCY EXPO: A COMMUNICATION BLUEPRINT FOR PUBLIC PREPAREDNESS IN INDONESIA Sira, Amaze Grace; Kristiyanto, Haryo Dimasto; Priskila, Loury
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

Based on BNPB data in 2024, there were 3,472 disasters in Indonesia, with the highest incidence being hydrometeorological disasters, which was 99.34% and geological disasters, 0.66% of the hydrometeorological disasters that occurred were floods and forest fires, in addition, there were 15 earthquakes and eight volcanic eruptions. In addition to natural disasters, emergencies often happen and claim many lives. According to data from the National Police Traffic Corps, throughout 2023, there were more than 150,000 cases of traffic accidents throughout Indonesia, with the death toll reaching more than 25,000 people. Method: This exhibition was held for 1 day by raising various topics related to disasters and emergencies in Indonesia. This activity not only invited the entire academic community of the Faculty of Medicine, Duta Wacana Christian University, but was also open to the public. Around 300 people attended this event, including UKDW students from medicine, other faculties, and the general public. All participants showed enthusiasm for this expo, from listening to the education provided to watching various theatrical performances and doing (hands-on) the mannequins or tools provided. The part organized by our tutorial group ran smoothly overall. All visitors showed enthusiasm in organizing the activity and participated in the entire series of activities. Keywords: communication strategy, disaster mitigation, emergency, medical, exhibition
Antibacterial and anti-adherence effect of Laportea interupta ethanolic extract on Streptococcus mutans biofilm Hutomo, Suryani; Larope, Ceny Gloria; Putri, Denise Utami; Sooai, Christiane Marlene; Kristiyanto, Haryo Dimasto
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 3 (2025): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i3.p256-261

Abstract

Background: Due to its capacity to generate extracellular polymeric substances that aid in biofilm creation, Streptococcus mutans is a leading cause of dental caries. Natural remedies, including traditional plant extracts, are being explored for their antimicrobial potential. Laportea interupta (L. interupta), known as jelatang in Indonesia, is alleged to possess a bacteria-inhibiting effect. Purpose: The purpose of this study is to evaluate the potential use of L. interupta leaf ethanolic extract to inhibit S. mutans proliferation and adherence to hydroxyapatite (HA) discs, simulating the tooth surface. Methods: The broth microdilution approach was utilized to evaluate the minimum concentration of the extract that inhibits bacterial growth. For anti-adherence assessment, HA discs pre-coated with saliva were exposed to different extract concentrations and incubated with S. mutans. Bacterial adhesion was visualized using 0.1% crystal violet staining, quantified spectrophotometrically at 595 nm, and further verified using scanning electron microscopy (SEM). Results: The extract showed inhibitory effects on S. mutans growth at 7,500 μg/ml (MIC). Anti-adherence activity was optimal at 1,500 μg/ml, and SEM analysis confirmed a reduced biofilm formation on extract-treated samples. Conclusion: Laportea interupta ethanolic leaf extract demonstrated both antibacterial and anti-adherence effects against S. mutans, suggesting its potential as a natural anti-biofilm agent for oral health applications.
Safety and Efficacy of Lutein and Zeaxanthin in the AREDS2 Formulation for Age-Related Macular Degeneration: Literature Review Kristiyanto, Haryo Dimasto; Sira, Amaze Grace; Wibisana, Yosafat Reza Herlambang; Tamma, Haryadi Aristo; Danuartha, Made Anom
Cermin Dunia Kedokteran Vol 53 No 10 (2026): Oktober 2026 - CDK 357
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i10.2174

Abstract

Age-related macular degeneration (AMD) is a progressive degenerative disease of the central retina and is a leading cause of vision loss among older adults worldwide. The original Age-Related Eye Disease Study (AREDS) supplement formula reduced the risk of progression to advanced AMD. However, the beta-carotene in this formula was associated with a higher risk of lung cancer in current and former smokers. AREDS2 evaluated lutein and zeaxanthin as safer substitutes for beta-carotene. These macular carotenoids have antioxidant effects and a better safety profile. Studies show that lutein and zeaxanthin help slow AMD progression through antioxidant effects and retinoprotective mechanisms. Researchers have also studied genetic factors, including complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2). However, current evidence is not strong enough to support individualized treatment based on these factors. Overall, lutein and zeaxanthin appear to provide a favorable balance of efficacy and safety as replacements for beta-carotene in the AREDS2 formulation.
Co-Authors Christiane Marlene Sooai, Christiane Marlene Danuartha, Made Anom Denise Utami Putri, Denise Utami Larope, Ceny Gloria Priskila, Loury Sira, Amaze Grace Suryani Hutomo, Suryani Tamma, Haryadi Aristo Wibisana, Yosafat Reza Herlambang