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All Journal Damianus Journal of Medicine Dental Journal (Majalah Kedokteran Gigi) MEDICINUS Jurnal Atma Inovasia
Christiane Marlene Sooai, Christiane Marlene
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Hubungan antara Sukungan Sosial, Jenis Kelamin, dan Tingkat Pendidikan dengan Depresi dan Fungsi Kognitif Lanjut Suia dalam Komunitas Keagamaan Jayadi, Tejo; The, Maria Meiwati Widagdo; Sooai, Christiane Marlene; Indonesia, Bunga Matahari; Agustina, Maria; Waskitaningtyas, Bernadeta Amaya
Bahasa Indonesia Vol 23 No 3 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i3.6002

Abstract

Introduction: Elderly individuals often experience psychosocial vulnerabilities that increase their risk for psychological disorders and are linked to cognitive impairments. This study explored how social support and demographic variables relate to the incidence of depression and cognitive decline among devout older adults. Methods: This cross-sectional observational study involved 125 senior participants from the Javanese Christian Church in Ambarrukma District of Yogyakarta. The research utilized demographic questionnaires, social support evaluations, surveys on religious attitudes, the Geriatric Depression Scale, and the MOCA-Ina tests. Data will undergo univariate and bivariate analyses and binary linear regression to evaluate odds ratios (OR), 95% confidence intervals (CI), and Pearson correlations between variables. Results: Elderly devout respondents (99.2%) who received good social support were more likely to experience no depression (47.9%) than those with poor social support (40.3%) (p=0.025; OR 0.182; 95% CI 0.038-0.873). The female gender suffered more from mild depression (p=0.021; OR 0.176; 95% CI 0.037-0.841) compared to men. Older adults with an education level of 7 years or more showed less mild cognitive impairment (p=0.044; OR 4.500; 95% CI 0.929-21.802). Conclusion: This study revealed that social support plays a role in modifying the incidence of depression in devout elderly individuals. The female gender suffered more from mild depression. Additionally, lower education levels were correlated with mild cognitive impairment. Further research with a more robust analysis with a larger sample size and consideration of other factors is necessary to confirm the causal relationships between social support and gender and depression.  
Antibacterial and anti-adherence effect of Laportea interupta ethanolic extract on Streptococcus mutans biofilm Hutomo, Suryani; Larope, Ceny Gloria; Putri, Denise Utami; Sooai, Christiane Marlene; Kristiyanto, Haryo Dimasto
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 3 (2025): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i3.p256-261

Abstract

Background: Due to its capacity to generate extracellular polymeric substances that aid in biofilm creation, Streptococcus mutans is a leading cause of dental caries. Natural remedies, including traditional plant extracts, are being explored for their antimicrobial potential. Laportea interupta (L. interupta), known as jelatang in Indonesia, is alleged to possess a bacteria-inhibiting effect. Purpose: The purpose of this study is to evaluate the potential use of L. interupta leaf ethanolic extract to inhibit S. mutans proliferation and adherence to hydroxyapatite (HA) discs, simulating the tooth surface. Methods: The broth microdilution approach was utilized to evaluate the minimum concentration of the extract that inhibits bacterial growth. For anti-adherence assessment, HA discs pre-coated with saliva were exposed to different extract concentrations and incubated with S. mutans. Bacterial adhesion was visualized using 0.1% crystal violet staining, quantified spectrophotometrically at 595 nm, and further verified using scanning electron microscopy (SEM). Results: The extract showed inhibitory effects on S. mutans growth at 7,500 μg/ml (MIC). Anti-adherence activity was optimal at 1,500 μg/ml, and SEM analysis confirmed a reduced biofilm formation on extract-treated samples. Conclusion: Laportea interupta ethanolic leaf extract demonstrated both antibacterial and anti-adherence effects against S. mutans, suggesting its potential as a natural anti-biofilm agent for oral health applications.
The Role of Systemic Immune-Inflammation Index on The Clinical Degree of Dengue Hemorrhagic Fever Patients at Bethesda Hospital Yogyakarta Amumpuni, Antonia Namelia Wahyu; Sooai, Christiane Marlene; Wicaksono, Hendi; Probowati, Wiwiek; Priskila, Loury
MEDICINUS Vol. 38 No. 8 (2025): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/y6daha15

Abstract

Background: Dengue hemorrhagic fever (DHF) is a mosquito-borne infectious disease caused by the dengue virus and transmitted primarily by Aedes aegypti. According to the World Health Organization (WHO), DHF remains a major globalhealth concern, particularly in tropical and subtropical regions. The disease can result in severe complications, including hemorrhage and hypovolemic shock, which may lead to death. Despite ongoing vector control initiatives, DHF continues to pose a significant public health challenge, especially in areas with inadequate sanitation and limited healthcare infrastructure.Objectives: To evaluate the role of systemic immune-inflammation index (SII) in determining the clinical severity of denguehemorrhagic fever (DHF) among patients at Bethesda Hospital Yogyakarta.Methods: This was a cross-sectional study utilizing medical records from 333 DHF patients at Bethesda Hospital Yogyakarta. Records were screened based on predefined inclusion and exclusion criteria. A total of 172 eligible cases were selected using odds ratio-based sample size calculations. Consecutive sampling was employed as the samplingtechnique. Data analysis was performed using SPSS and Microsoft Excel to determine statistical significance.Results: The findings demonstrated that neutrophil, lymphocyte, and platelet counts significantly influenced the clinical severity of dengue hemorrhagic fever (DHF). Chi-square analysis revealed a statistically significant association between the systemic immune-inflammation index (SII) and disease classification (DF/DHF) (p<0.001). However, the relationshipbetween SII levels and clinical severity did not follow a linear pattern. Contrary to established theories—where elevated SII values are typically associated with increased disease severity—this study observed variations that may be attributed toconfounding factors such as patient age, comorbidities, and individual immune response.Conclusion: The systemic immune-inflammation index (SII) is significantly associated with the clinical severity of DHF in patients at Bethesda Hospital Yogyakarta, although its correlation may be influenced by additional patient-specificvariables such as patient age, comorbidities, and individual immune responses.Keywords: systemic immune-inflammation index (SII), dengue hemmorhagic fever (DHF), dengue severity, clinicalseverity.
Pelatihan Pengolahan Tanaman Obat Keluarga (TOGA) Menjadi Kosmetika di Wilayah Kapanewon Sanden Krismi, Arum; Sooai, Christiane Marlene; Kurniawati, Novika; Hutomo, Suryani
Jurnal Atma Inovasia Vol. 5 No. 5 (2025)
Publisher : Lembaga Penelitian dan Pengabdian pada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/jai.v5i5.10365

Abstract

Kosmetika adalah sediaan yang dimaksudkan untuk digunakan pada bagian luar tubuh manusia dengan tujuan antara lain untuk membersihkan tubuh. Salah satu produk kosmetika yang diminati adalah kosmetika yang mengandung bahan rempah, yang banyak ditanam oleh masyarakat sebagai Tanaman Obat Keluarga (TOGA). Tujuan akhir kegiatan pengabdian kepada masyarakat ini adalah meningkatkan pengetahuan tentang manfaat TOGA khususnya untuk kesehatan kulit, serta meningkatkan keterampilan pengolahan TOGA menjadi sediaan kosmetika untuk 90 orang kader Asuhan Mandiri TOGA di wilayah Kapanewon Sanden. Kegiatan pengabdian masyarakat dilaksanakan dengan penyampaian materi mengenai keluhan kulit dan keamanan lulur bahan alam, bentuk sediaan kosmetika, bahan alam yang dapat digunakan untuk kesehatan gigi dan mulut, pembuatan lulur dan sabun dari TOGA, kemudian dilanjutkan dengan praktek pelatihan pengolahan TOGA menjadi lulur. Lulur yang diproduksi oleh kader dan masyarakat telah digunakan oleh masyarakat dan keluarganya
Co-Authors Amumpuni, Antonia Namelia Wahyu Arum Krismi, Arum Denise Utami Putri, Denise Utami Hendi Wicaksono Indonesia, Bunga Matahari Kristiyanto, Haryo Dimasto Kurniawati, Novika Larope, Ceny Gloria MARIA AGUSTINA Priskila, Loury Probowati, Wiwiek Suryani Hutomo, Suryani Tejo Jayadi, Tejo The, Maria Meiwati Widagdo Waskitaningtyas, Bernadeta Amaya