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Rehabilitasi Poskestren Berbasis Kader Santri Husada untuk Mewujudkan Pesantren Sehat di Pesantren Tahfidz Qur’an Nurul Bahri Sanana Abulkhair Abdullah; Muhammad Fakhrur Rajih Hi. Yusuf; Dwi Fitriani
Abdi Wiralodra : Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2026): Abdi Wiralodra
Publisher : universitas wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/abdi.v8i1.372

Abstract

Pesantren merupakan lembaga pendidikan Islam yang tidak hanya berperan dalam aspek religius, tetapi juga sebagai pusat pembinaan karakter, sosial, dan budaya santri. Namun, banyak pesantren di wilayah kepulauan menghadapi keterbatasan layanan kesehatan, termasuk Pondok Pesantren Tahfidz Qur’an (PPTQ) Nurul Bahri Sanana yang belum memiliki Pos Kesehatan Pesantren (Poskestren). Program Pengabdian kepada Masyarakat ini bertujuan merehabilitasi Poskestren dan memberdayakan kader Santri Husada sebagai ujung tombak pelayanan kesehatan di lingkungan pesantren. Metode pelaksanaan mencakup sosialisasi, rehabilitasi sarana kesehatan, pembentukan pengelola Poskestren, edukasi kesehatan, serta pelatihan penggunaan alat kesehatan dasar. Edukasi kesehatan diberikan dengan materi Perilaku Hidup Bersih dan Sehat (PHBS), Pendidikan Keterampilan Hidup Sehat (PKHS), Dapatkan, Gunakan, Simpan, dan Buang obat yang baik (DaGuSiBu), serta Pertolongan Pertama pada Penyakit (P3P). Hasil kegiatan menunjukkan Poskestren dapat difungsikan kembali dengan sarana kesehatan yang memadai dan terbentuknya pengelola Poskestren.
Efektivitas ekstrak daging buah pala (Myristica fragrans Houtt) terhadap histopatologi hati pada tikus hiperglikemia Nur, Amran; Nur, Safitri Hasda; S. Somadayo, Nur Asma; Rajih, Muhammad Fakhrur
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1927

Abstract

Background: Hyperglycemia can occur due to insulin resistance, which affects the metabolism of lipids, carbohydrates, proteins, and fatty acids in the liver, which will ultimately cause cirrhosis, steatohepatitis, liver cancer, and other liver disorders.Objectives: To determine the effect of administering nutmeg pulp extract (Myristica fragrans H.) on the histopathological picture of the liver of hyperglycemic mice induced by high carbohydrate feed.Methods: The research was carried out using an experimental method using 25 white rats (Rattus norvegicus) of the Wistar strain, which were divided into five groups, K- (NaCMC 1%), K+ (Metformin), P1-P3 respectively Nutmeg extract 100mg/kgBW, 200mg/kgBB, 300mg/kgBB). The entire group was given high carbohydrate feed for 30 days, then extract and Metformin for seven days. On the 36th day, the liver was removed, and histopathology preparations were made. The main research outcome parameters include initial blood sugar levels before induction (T0), final day blood sugar levels (T30), blood sugar levels on days 1, 3, 5, and 7 after sample administration, liver weight, and liver severity score. The data obtained were analyzed using Oneway-Anova with a significance of 0.05, and LSD as a further testResults: The K+, P1, and P3 groups showed a significant reduction in sugar compared to the control group (p<0.05), but all groups did not show an improvement in liver histopathology with damage scores in the mild to severe damage category.Conclusion: Nutmeg pulp extract at doses of 100mg/kgBB, 200mg/kgBB, and 300mg/kgBB showed effectiveness in reducing blood sugar in hyperglycemic white mice but could not show optimal improvement in liver cell damage.Keywords:Diabetes mellitus, Histopatology, Liver, Myristica fragrans, Nutmeg Flesh.
The Immunomodulatory Potential of Ethanolic Extract of Blue Butterfly Pea Flower (Clitoria ternatea) on Non-Specific Immune Mechanisms Fiskia, Ermalyanti; Karim, Muhammad Azhar A; Hi Yusuf, Muhammad Fakhrur Rajih; Azzahra, Rufaidah; Rahman, Ismail
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/s67fbc03

Abstract

The immune system is a complex mechanism consisting of cells, tissues, and organs that work in coordination to protect the body from exposure to pathogens. However, pathogens also possess strategies to counteract immune defenses, thereby necessitating external substances to support immune enhancement. One such substance is antioxidants. Butterfly pea flower (Clitoria ternatea) is a potential candidate as an immunomodulator due to its high antioxidant content, which functions to prevent lipid peroxidation and combat free radicals. This study aims to investigate the immunomodulatory potential of the ethanol extract of butterfly pea flower using the carbon clearance test in mice. The research method was experimental, employing 30 BALB/c mice as test animals, which were divided into six groups: Butterfly Pea Flower Extract (EBTB) at doses of 150, 300, and 600 mg/kg BW, levamisole 25 mg and methylprednisolone 4 mg as comparison groups, and sodium CMC as the negative control group. The substances were administered orally for seven consecutive days, followed by intravenous induction of carbon ink on day 8. The obtained serum was measured for absorbance using UV-Vis spectrophotometry at 650 nm. Parameters observed included the phagocytic index (PI) and lymphoid organ index (liver, spleen, and thymus). Based on the phagocytic index calculation, EBTB at doses of 150 and 300 mg/kg BW yielded values of 2.990 and 2.929, respectively, indicating strong immunostimulant activity, while BPFE at 600 mg/kg BW showed moderate immunostimulant activity with a PI value of 1.423. Results for the lymphoid organ index in the BPFE 150 group did not show significant differences (P > 0.05) compared to the control group. In conclusion, the ethanol extract of butterfly pea flower demonstrates potential as an immunomodulator for nonspecific immune responses.