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All Journal Jurnal Kesehatan Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Human Care Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research
Weni Helvinda
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Human Care Journal

 1 
INJEKSI INTRAVITREAL RANIBIZUMAB PADA POLYPOIDAL CHOROIDAL VASCULOPATHY (PCV) Haris Budiman; Weni Helvinda
HUMAN CARE JOURNAL Vol 5, No 4 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i4.860

Abstract

Introduction: Polypoidal choroidal vasculopathy (PCV) is a peculiar form of choroidal neovascularization characterized by protrusion of the aneurysm at the end of the choroidal blood vessels. The aim of this study is to report a case of   PCV in a young woman who treated with intravitreal ranibizumab injection. Method: The patient undergoes general ophthalmic examinations, amsler grid, funduscopic photography and OCT analysis. The repeated examination performed after intravitreal injection of ranibizumab to assess the effect of therapy. Result:  Two weeks after intravitreal ranibizumab injection, the visual acuity was improved and on OCT examination revealed decreasing in macular thickness. Conclusion: Intravitreal ranibizumab injection can give good result, but in this case the effectiveness hasn’t so evident because of the administration only once and follow-up only in two weeks.
PERBANDINGAN RETINAL GANGLION CELL THICKNESS DAN PERIMETRI PASIEN DIABETES MELITUS TIPE 2 sherly muchlis muchlis; Ardizal Rahman; Weni Helvinda
HUMAN CARE JOURNAL Vol 5, No 3 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i3.788

Abstract

Diabetic retinopathy (RD) is a microvascular complication that often occurs in diabetes mellitus (DM). Retinal ganglion cells (RGC) are reduced in the early stages of DM, even before microvascular abnormalities are seen on the retina. Methods: Sample of 35 eyes of non RD RD type 2 patients and 35 mild non proliferative diabetic retinopathy (NPDR) eyes After examination of ophthalmological status, perimetry and optical coherence tomography (OCT) were examined. Results: The mean MD on non-RD type 2 DM -2.74 ± 3.5 mild NPDR -5.61 ± 4.5 with p value 0.414. The average non-RD type 2 PSD DM was -3.35 ± 3.3, mild NPDR was 4.16 ± 1.4 with a p value of 0.206. The mean RGC thickness of patients with non-RD type 2 DM was 83.8 ± 7.4 µm, mild NPDR 82.7 ± 8.1 μm. There was a decrease in the value of RGC thickness, MD and PSD in patients with type 2 DM, but it was not statistically significant . Conclusion: No significant difference was found in RGC thickness in DM patients between non-RD and mild NPDR. No significant difference was found between MD and PSD in DM patients between non-RD and mild NPDR. No significant relationship was found between RGC thickness and perimetry in DM patients between non-RD and mild NPDR. 
TOKSOPLASMOSIS OKULAR dessy ariyeni; Weni Helvinda
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.783

Abstract

Tujuan: Toksoplasmosis merupakan penyakit yang disebabkan oleh Toksoplasma gondii yang merupakan protozoa obligat intraselular. Parasit ini mempunyai 3 bentuk morfologi yang berbeda, yaitu: tachizoites, bradizoites dan ookista. Transmisi parasit ke manusia dapat terjadi dengan cara termakan makanan yang mengandung ookista atau kista jaringan yang terdapat di dalam daging yang dimasak tidak sempurna. Metode: Pada laporan kasus ini dilaporkan kasus dengan diagnosis toksoplasmosis okular pada 5 pasien yang datang ke RS Dr. M. Djamil Padang antara bulan Februari – Mei 2015. Lima  pasien datang dengan keluhan penglihatan kabur dengan onset yang berbeda-beda. Hasil: Pada pemeriksaan oftalmologi didapatkan penurunan visus unilateral dan terdapatnya lesi di polus posterior dengan pinggir hiperpigmentasi pada pemeriksaan funduskopi. Semua pasien diberikan terapi trimethoprim / sulfamethoxazole  selama 6 minggu. Kesimpulan: Perbaikan visus pada pasien toksoplasmosis okular terjadi setelah pemberian terapi selama 6 minggu dengan terapi trimethoprim / sulfamethoxazole walaupun tidak terlalu signifikan karena terdapatnya lesi didaerah makula.
Co-Authors Anak Agung Gede Sugianthara Andrini Ariesti Ardizal Rahman Arini Ghaisa Atsari dessy ariyeni Hendriati Kemala Sayuti Khalilul Rahman lonanda, Gama Agusto NOVIAN ADI SAPUTRA sherly muchlis muchlis Vitresia, Havriza