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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research
lonanda, Gama Agusto
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Immunology & microbiology Medicine & Pharmacology Neuroscience Social Sciences Other

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Screening Cataract and Other Visual Impairment by PELITA Cadre to Build Vision Center in Lima Puluh Kota Regency Ariesti, Andrini; Hendriati, Hendriati; Hidayat, Muhammad; Irayanti, Irayanti; Ilahi, Fitratul; Yuswir, Astria Rima Rara; Lonanda, Gama Agusto; Primasakti, Pattih; Roza, Silvia; Syafendra, Atika; Afelita, Tia; Putra, Heru Ardila; Suhery, Suhery; Irza, Metika Rahmasari; Lucyana, Lucyana; Maralaut, Azhardin; Zulferza, Jaka
Warta Pengabdian Andalas Vol 32 No 3 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.3.390-399.2025

Abstract

Eye diseases, particularly cataracts, are the leading cause of blindness worldwide. This community service program by the Department of Ophthalmology, Faculty of Medicine, Andalas University, was conducted at the Pangkalan Public Health Center, Lima Puluh Kota Regency, by empowering PELITA (Posyandu) cadres in early detection of cataracts. Methods included counseling, training, and eye examination simulations for 40 cadres, followed by community screening using visual acuity and anterior segment examinations. Evaluation was carried out with pre- and post-tests, satisfaction surveys, and follow-up on patients referred for surgery. The average cadre score improved from 68 (pre-test) to 74.5 (post-test), indicating increased knowledge. A total of 71 patients were screened, including 40 cataract and 8 pterygium cases; 26 cataract and 4 pterygium patients subsequently underwent surgery. Cadres reported high satisfaction with the training and expressed readiness to continue participation. This program demonstrates that cadre training is effective in improving early detection of cataracts and other visual impairments, and provides a foundation for establishing a Vision Center in Lima Puluh Kota.
Changes in Retinal Ganglion Cell (RGC) and Retinal Nerve Fiber Layer (RNFL) Thickness in Children with Type 1 Diabetes Mellitus at Dr. M. Djamil General Hospital, Padang, Indonesia lonanda, Gama Agusto; Kemala Sayuti; Havriza Vitresia; Hendriati; Andrini Ariesti; Weni Helvinda
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 8 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i8.1047

Abstract

Background: Type 1 diabetes mellitus (DM) is a chronic metabolic disorder that causes hyperglycemia and increases the risk of morbidity and mortality. Diabetic retinopathy, a microvascular complication that often occurs in DM patients, can cause visual impairment and even blindness. Regular eye examinations are important for early detection of diabetic retinopathy. Optical coherence tomography (OCT) is a non-invasive method that can be used to measure the thickness of retinal layers, including RGC and RNFL. It is thought that thinning of the retinal layer can be a sensitive biomarker in detecting diabetic retinopathy in type 1 DM patients. This study aims to determine changes in RGC and RNFL thickness in children with type 1 DM. Methods: This cross-sectional design analytical observational study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital Padang in November 2023-March 2024. A total of 46 eyes from 46 people, divided into two groups: the type 1 DM group and the control group, were recruited in this study. RGC thickness was measured using AS-OCT GC-IPL thickness analysis and RNFL with optic disc RNFL thickness analysis. Data analysis was carried out using the unpaired T-test. Results: The results showed RGC depletion in the type 1 DM group (RGC 83.48 ± 3.75) compared to the control group (RGC 86.70 ± 4.87) with a value of p = 0.016 (p < 0.05). There was no statistical difference in RNFL thickness between the type 1 DM group (RNFL 102 ± 11.80) and the control group (RNFL 100.96 ± 10.97) with a value of p = 0.581 (p> 0.05). Conclusion: This study found RGC thinning in type 1 DM patients, but did not find differences in RNFL thickness between the two groups. This RGC depletion is thought to be caused by apoptosis of retinal neuronal cells due to chronic hyperglycemia. Examination of RGC thickness with OCT can be developed as an early detection of diabetic retinopathy in children with type 1 DM.
Changes in Retinal Ganglion Cell (RGC) and Retinal Nerve Fiber Layer (RNFL) Thickness in Children with Type 1 Diabetes Mellitus at Dr. M. Djamil General Hospital, Padang, Indonesia lonanda, Gama Agusto; Kemala Sayuti; Havriza Vitresia; Hendriati; Andrini Ariesti; Weni Helvinda
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 8 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i8.1047

Abstract

Background: Type 1 diabetes mellitus (DM) is a chronic metabolic disorder that causes hyperglycemia and increases the risk of morbidity and mortality. Diabetic retinopathy, a microvascular complication that often occurs in DM patients, can cause visual impairment and even blindness. Regular eye examinations are important for early detection of diabetic retinopathy. Optical coherence tomography (OCT) is a non-invasive method that can be used to measure the thickness of retinal layers, including RGC and RNFL. It is thought that thinning of the retinal layer can be a sensitive biomarker in detecting diabetic retinopathy in type 1 DM patients. This study aims to determine changes in RGC and RNFL thickness in children with type 1 DM. Methods: This cross-sectional design analytical observational study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital Padang in November 2023-March 2024. A total of 46 eyes from 46 people, divided into two groups: the type 1 DM group and the control group, were recruited in this study. RGC thickness was measured using AS-OCT GC-IPL thickness analysis and RNFL with optic disc RNFL thickness analysis. Data analysis was carried out using the unpaired T-test. Results: The results showed RGC depletion in the type 1 DM group (RGC 83.48 ± 3.75) compared to the control group (RGC 86.70 ± 4.87) with a value of p = 0.016 (p < 0.05). There was no statistical difference in RNFL thickness between the type 1 DM group (RNFL 102 ± 11.80) and the control group (RNFL 100.96 ± 10.97) with a value of p = 0.581 (p> 0.05). Conclusion: This study found RGC thinning in type 1 DM patients, but did not find differences in RNFL thickness between the two groups. This RGC depletion is thought to be caused by apoptosis of retinal neuronal cells due to chronic hyperglycemia. Examination of RGC thickness with OCT can be developed as an early detection of diabetic retinopathy in children with type 1 DM.
Co-Authors Afelita, Tia Andrini Ariesti Ariesti, Andrini Astria Rima Rara Yuswir Hendriati Hendriati, Hendriati Heru Ardila Putra Ilahi, Fitratul Irayanti, Irayanti Irza, Metika Rahmasari Kemala Sayuti Lucyana Lucyana, Lucyana Maralaut, Azhardin Muhammad Hidayat Primasakti, Pattih Roza, Silvia Suhery, Suhery Syafendra, Atika Vitresia, Havriza Weni Helvinda Zulferza, Jaka