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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Darmabakti Cendekia: Journal of Community Service and Engagements Jurnal Layanan Masyarakat (Journal of Public Service)
Rahmanto, Ilham
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Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Medicine & Pharmacology Public Health Social Sciences Other

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IMPROVING KNOWLEDGE AND ATTITUDES ABOUT CERVICAL CANCER DETECTION IN JAVA'S PANTURA REGION: PENINGKATAN PENGETAHUAN DAN SIKAP TENTANG DETEKSI KANKER SERVIKS DI PANTURA PULAU JAWA Rahmanto, Ilham; Hanum, Safa Salsabila; Safitri, Cahyani Tiara; Khaerana, A. Insyirah; Targanski, Constantia Lidwina; Hendrarto, Bagus Adjie Dwi; Hartawan, M. Wildan Nabalah; Susilo, Imam
Darmabakti Cendekia: Journal of Community Service and Engagements Vol. 7 No. 1 (2025): JUNE 2025
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/dc.V7.I1.2025.1-7

Abstract

Background: Early detection of cervical cancer through IVA and Pap smear examination is crucial for preventing and reducing cervical cancer mortality. However, IVA and Pap smear coverage in Indonesia, particularly in Mentaras Village, Gresik Regency, remains low. The low knowledge and attitudes of women of childbearing age towards IVA and Pap smear examinations are major obstacles to early detection. Objective: This community service aims to improve the knowledge and attitudes of women of childbearing age in Mentaras Village towards IVA and Pap smear examinations through health socialization. Method: Health socialization was conducted for 23 participants from the PKK mothers' group using PowerPoint presentations and brochures. Evaluation was performed using a post-test questionnaire to measure participants' knowledge and attitudes after the activity. Results: After the socialization, all participants (100%) demonstrated a good level of knowledge, and 91.30% showed a positive attitude towards IVA and Pap smear examinations. These results indicate that the socialization activity positively impacted participants' awareness. Conclusion: Health socialization effectively improved understanding and attitudes towards the early detection of cervical cancer. Regular similar activities are recommended to expand community participation.
EMERGENCY RESPONSE TRAINING FOR FLOOD TIDES: ENHANCING PREPAREDNESS OF THE KEDUNG COWEK COASTAL COMMUNITY, SURABAYA Pujo Semedi, Bambang; Kriswidiyatomo, Prihatma; Surgean Veterini, Anna; Sumartono Waloejo, Christrijogo; Abbas, Kun Arifi; Perdhana, Fajar; Mutiar, Airi; Rahmanto, Ilham; Rifqi, Muhammad Andika
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 3 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i3.2025.495-506

Abstract

Tidal flooding is one of the hydrometeorological disasters caused by extreme weather that frequently affects the coastal area of Kampung Nelayan, Kedung Cowek Subdistrict, Surabaya City. Based on risk analysis, the community’s level of knowledge and attitude in responding to disasters plays a crucial role in mitigation efforts; thus, training and the initiation of a disaster response community are necessary. This community service program aimed to provide theoretical education and practical training on Basic Life Support (BLS), accompanied by the initiation of a fishermen disaster response community for 35 people of Kampung Nelayan, Kedung Cowek. The program was conducted at the Kedung Cowek Village Hall and included: (1) BLS education through presentations, (2) practical simulation of chest compressions using a mannequin and evacuation with a stretcher, (3) distribution of personal protective equipment for fishermen, and (4) the establishment of a disaster response community. Improvements in knowledge and attitude were measured using pre- and post-test questionnaires and analyzed with the Wilcoxon Signed-Rank test in SPSS with significance level at 0,05. The results showed a significant increase in knowledge (68.66 ± 21.68 vs 95.33 ± 2.61) and attitude (50.71 ± 14.24 vs 64.95 ± 3.27) (p < 0.01). The initiation of a disaster response coastal community is expected to strengthen the tidal flood management system through adequate BLS provision, so the capacity and resilience of coastal communities are sustainably maintained.
Tandem peptide lipid CRISPR-Cas9 complex combating APP and APOE4 gene abnormality in Alzheimer's disease Rahmanto, Ilham; Cahyono, Maulana Bagus Adi; Khatimah, Husnul; Nugraningrum, Rahmi; Putri, Pionera Seconda Giyanti; Sahiruddin, Nurul Zulfa; Rahmaniah, Nabila; Romadhon, Pradana Zaky
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 01 (2024): Qanun Medika Vol 08 No 01 January 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i01.16054

Abstract

Alzheimer's attacks 24 million global population and dominates 60-80% of existing cases of dementia. It causes the accumulation of beta-amyloid (Aβ) plaques in the hippocampus and entorhinal cortex, resulting in decreased mass from the brain. Recent studies have shown that the manifestation of this disease is due to an overaccumulation of abnormal Aβ protein due to abnormalities in the APP and APOE4 genes. Point mutations in the APP gene will create the toxic form of Aβ protein, namely Aβ42, and the toxic APOE4 gene will accelerate the onset of Aβ42 deposition and pro-inflammatory activity that exacerbates the degenerative process of the brain. Gene editing as a potential definitive therapy was recently a concern by researchers. CRISPR-Cas9 repairs the APP gene and substitutes the APOE4 gene with APOE3 by modifying the gene's DNA sequence. Nano complex CRISPR-Cas9 tandem peptide lipid is a model for clinicians to target brain nerve cells. In vivo research on an Alzheimer's mouse model proved the potential of nano-complex-based peptides as carriers of CRISPR-Cas9 in brain nerve cells. This engineering technology offers satisfactory results with high precision, minimal side effects, and a relatively low price for long-term therapeutic effects and even a lifetime.
Co-Authors Abbas, Kun Arifi Anna Surgean Veterini Cahyono, Maulana Bagus Adi Hanum, Safa Salsabila Hartawan, M. Wildan Nabalah Hendrarto, Bagus Adjie Dwi Husnul Khatimah Imam Susilo Khaerana, A. Insyirah Kriswidiyatomo, Prihatma Mutiar, Airi Nugraningrum, Rahmi Perdhana, Fajar Putri, Pionera Seconda Giyanti Rahmaniah, Nabila Rifqi, Muhammad Andika Romadhon, Pradana Zaky Safitri, Cahyani Tiara Sahiruddin, Nurul Zulfa Semedi, Bambang Pujo Sumartono Waloejo, Christrijogo Targanski, Constantia Lidwina