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All Journal Jurnal Kesehatan Masyarakat The Indonesian Biomedical Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Midwifery Majalah Kedokteran Andalas Jurnal Sehat Mandiri Contagion: Scientific Periodical Journal of Public Health and Coastal Health Andalas obstetrics and gynecology journal Science Midwifery Jurnal Ilmu Kesehatan Indonesia (JIKSI)
Hudila Rifa Karmia
Andalas University
Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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HUBUNGAN ASUPAN BESI HEME DAN NON-HEME KADAR FERRITIN PADA CALON PENGANTIN PEREMPUAN DI KOTA PADANG Ulya Uti - Fasrini; Wiyola Audina; Defrin Defrin; Desmawati Desmawati; Hudila Rifa Karmia; Abdiana Abdiana
Jurnal Sehat Mandiri Vol 16 No 1 (2021): Jurnal Sehat Mandiri, Volume 16, No.1 Juni 2021
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (198.852 KB) | DOI: 10.33761/jsm.v16i1.363

Abstract

Women of childbearing age are prone to anemia, especially iron-deficiency anemia. The outcome might be seen in the high maternal mortality rate in the Padang city (16 cases. Serum ferritin can be used as an initial indicator to determine iron deficiency. A decrease in serum ferritin levels can be influenced by iron intake. This study aimed to determine the relationship between heme and non-heme iron intake with ferritin serum concentration in women’s bride candidates in Padang City. This analytical study with a cross-sectional design involved 30 bride candidates, 20-30 years old. Iron intake were collected using the Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), and serum ferritin levels were measured using the Enhanced ChemiLuminescence Immuno Assay (ECLIA) method. Data were analyzed using the Pearson correlation coefficient test. The results showed the mean of heme and non-heme iron intake was 2.76 ± 0.90 mg/day and 3.83 ± 0.97 mg/day, respectively, and the mean of serum ferritin levels was 46.27 ± 27.61 ng/ml. The test showed no significant correlation between heme (r=0.094, p=0.622) and non-heme iron (r=-0.179, p=0.345) intake with serum ferritin levels. This study concludes that there is no relationship between heme and non-heme iron intake with serum ferritin levels on bride candidates in Padang City. Therefore, to prevent the incidence of anemia during pregnancy, it is highly recommended for the brides to increase their iron intake from both animal and vegetable sources.
Semen Quality of Infertile Men and Correlation with Demographic Characterictics Muhammad Iqbal; Hudila Rifa Karmia; Alvarino Alvarino
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.58-64.2022

Abstract

Objective: To analyze semen quality of infertile men and its correlation with demographics characteristics.Methods: This was an analytic observational study with cross-sectional retrospective study design on 92 infertile men. The study began in May 2021 to December 2021 in the Obstetrics and Gynecology Clinics at BMC Hospital Padang.Results:The correlation between age and marital duration was positively correlated (r= 0,558), with a weak correlation and there is statistically significant relationship between age and marital duration. Age and sperm concentration was positively correlated (r=0.048), with a weak correlation. Marital duration and sperm concentration was positively correlated (r=0.052), with a weak correlation. The correlation between age and progressive motility and non-progressive motility percentage were positively correlated (r = 0.009 and 0.035),with a weak correlation. The correlation between age and progressive immotile sperm percentage were negatively correlated (r = - 0,030),with a weak correlation.Conclusion: There was a positive correlation between age and sperm concentration, and progressive and non progressive motility with a weak correlation. There was a positive correlation between age and marital duration with a strong correlation. There was negative correlation between and sperm immotility with a weak correlation.Keywords:  male infertility, semen, age, marital duration
The Correlation of L-citrulline Levels with Blood Pressure in Severe Preeclampsia Hudila Rifa Karmia; Afriwardi Afriwardi; Hirowati Ali; Johanes Cornelius Mose; Yusrawati Yusrawati
The Indonesian Biomedical Journal Vol 12, No 1 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i1.964

Abstract

BACKGROUND: Based on 'vascular disorder of pregnancy' terminology, preeclampsia primarily was not a hypertensive disorder, but a vascular disorder (general vasospasm) in pregnancy due to idiopathic etiology. The overall incidence of preeclampsia was 5-14% of all pregnancies. One of the substances responsible for regulating vascular tone is nitric oxide (NO), which produced in endothelial blood vessels. NO and L-citrulline are produced altogether by the reaction between L-arginine and oxygen. L-citrulline levels reflected NO production. This study was aimed to assess the correlation between the L-citrulline level and blood pressure in severe preeclampsia.METHODS: This cross-sectional study was done in Dr. M. Djamil Central General Hospital, Padang, Indonesia The sample size was 36 samples of pregnant women with severe preeclampsia and had yet been given antihypertensive therapy. Sampling was done by consecutive sampling from Obstetrics and Gynecology Division. After maternal examination and measurements L-citrulline levels of cubital venous blood by using enzyme-linked immunosorbent assay (ELISA) method, Pearson correlation was performed to assess the relationship between variables for normally distributed data and Spearman's correlation for abnormal distribution data with significance level p<0.05.RESULTS: Means of L-citrulline levels, systolic blood pressure, diastolic blood pressure, and arterial pressure (MAP) were 87.21 nmol/mL, 179.4 mmHg, 108.3mmHg, and 132.1 mmHg, respectively. Correlation of the L-citrulline level with systolic blood pressure, diastolic blood pressure, and MAP were -0.08, -0.175, and -0.136 (p>0.05), respectively.CONCLUSION: L-citrulline levels had no correlation with blood pressure in severe preeclampsia.KEYWORDS: L-citrulline levels, blood pressure, severe preeclampsia
PERBEDAAN PERUBAHAN FUNGSI HEMOSTASIS SAAT STABILISASI PREEKLAMSIA BERAT/EKLAMSIA 24 JAM POSTPARTUM Hudila Rifa Karmia; Yusrawati Yusrawati; Hafni Bachtiar
Majalah Kedokteran Andalas Vol 39, No 1 (2016): Published in April 2016
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.66 KB) | DOI: 10.22338/mka.v39.i1.p28-34.2016

Abstract

Penelitian bertujuan menganalisis perbedaan perubahan temuan fungsi hemostasis saat stabilisasi antara preeklamsia berat/eklamsia yang mengalami dan yang tidak mengalami perbaikan 24 jam postpartum. Pada subyek penelitian yaitu wanita preeklamsia berat/eklamsia yang mengalami dan tidak mengalami perbaikan 24 jam postpartum dan memenuhi kriteria inklusi (16 pasien per kelompok) dilakukan pemeriksaan laboratorium fungsi hemostasis di Labor Patologi Klinik RSUP M. Djamil Padang. Perbedaan perubahan temuan fungsi hemostatik pada kedua grup dianalisa dengan menggunakan t-test. Dari penelitian didapatkan perbedaan temuan fungsi hemostasis pada saat stabilisasi antara preeklamsia berat/eklamsia yang mengalami dan yang tidak mengalami perbaikan 24 jam postpartum adalah trombosit 40.000 + 39.653/ml banding -5.250 + 58.915/ml (p=0,016), PT -0,144 + 1,083 detik banding 0,038 + 1,549 detik (p=0,074), APTT -0,275 + 3,938 detik banding 1,55 + 4,99 detik (p=0,260), dan D-dimer 0,319 + 1,34 ug/L banding 0,7125 + 2,018 ug/L (p=0,521). Sehingga dapat disimpulkan bahwa terdapat peningkatan yang bermakna secara statistik kadar trombosit kelompok yang mengalami perbaikan dibandingkan kelompok yang tidak mengalami perbaikan. Tidak terdapat perbedaan bermakna kadar PT, APTT, dan D-Dimer antara kelompok yang mengalami perbaikan dan kelompok yang tidak mengalami perbaikan.
Pathophysiology of Preeclamsia Hudila Rifa Karmia; Joserizal Serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.94-102.2022

Abstract

The uncertainty of the etiology and underlying mechanisms of the pathophysiology of this disease makes causal structuring and primary prevention of preeclampsia impossible, making it difficult to control morbidity and mortality, both maternal and perinatal. From the many theories on preeclampsia, the disease can be classified into Placental preeclampsia, maternal preeclampsia, and Vascular Disorders of Pregnancy (VDP). Increased inflammatory response to placental factors, excessive inflammatory response to placental factors, and primary vascular disorders are the basis of distinction and also the basis of pathophysiology among the three forms of preeclampsia.
Fetus Cardiovasculler Yusrawati yusrawati; Muhammad Iqbal; Reyhan Julio azwan; Bobby Indra Utama; Joserizal Serudji; Hudila rifa karmia
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.24-34.2022

Abstract

Formation of the human heart involves complex biological signals, interactions, specification of myocardial progenitorcells, and heart tube looping. To facilitate survival in the hy poxemic intrauterine environment, the fetus possessesstructural, physiological, and functional cardiovascular adaptations that are fundamentally different from the neonate. The  fetal  circulation is considered to anatomical and biochemical changes in the cardiovascular system. This review article describes key cardiac progenitors involved in embryonic heart development; the cellular, physiological, and anatomical changes during the transition from fetal to neonatal circulation.
Gambaran Pemeriksaan CT Scan Abdomen pada Pasien Tumor Ovarium di RSUP DR. M. Djamil Padang Tahun 2019-2020 Hafidz Aryan Abdillah; Dina Arfiani Rusjdi; Hudila Rifa Karmia
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 3 (2021): September 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v2i3.546

Abstract

Latar Belakang : Tumor ovarium merupakan tumor ganas terbanyak ke 3 pada wanita. Keterlambatan mendiagnosis dapat meningkatkan morbiditas dan mortalitas dari tumor ovarium. Computerized Tomography Scanner (CT-scan) abdomen merupakan pemeriksaan radiologi pertama untuk mendeteksi dan menentukan stadium keganasan ovarium. Penelitian ini bertujuan untuk mengetahui gambaran CT-scan abdomen pasien tumor ovarium. Objektif: Untuk mengetahui gambaran pemeriksaan CT-Scan Abdomen yang dilakukan pada pasien tumor ovarium di RSUP Dr. M. Djamil Padang tahun 2019-2020 Metode: Penelitian ini merupakan penelitian deskriptif retrospektif menggunakan data-data rekam medis pasien tumor ovarium yang telah dilakukan CT-scan abdomen di RSUP Dr M Djamil Padang tahun 2019-2020. Teknik pengambilan sampel menggunakan total sampling dengan jumlah sampel sebanyak 40 orang. Penelitian ini menggunakan analisis univariat untuk distribusi frekuensi. Hasil: Hasil penelitian didapatkan 60% pasien tumor ovarium terjadi pada pasien berusia ≤50 tahun dengan paritas 82,5% pernah melahirkan. Gambaran CT-scan abdomen pasien tumor ovarium terbanyak adalah gambaran komponen kistik (52,5%) dengan 57,5% sampel tidak memiliki gambaran penyerta. Asites merupakan gambaran penyerta terbanyak sebesar (17,5%). Hasil pemeriksaan patologi anatomi tumor ovarium terbanyak adalah tumor ovarium epithelial (77,5%). Kesimpulan: Terdapat beberapa karakteristik pasien pada tumor ovarium yang dikakukan pemeriksaan CT-Scan Abdomen. Penelitian ini membutuhkan analisis komponen CT-Scan abdomen dengan tingkat suatu keganasan pada tumor ovarium serta menggunaan faktor risiko lainnya.
The Association of Maternal Sleep Quality with Newborn Health Rahmi Andrita Yuda; Amel Yanis; Hudila Rifa Karmia
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.1053

Abstract

Sleep disturbances in pregnancy according to the literature, they can affect newborn outcomes also can impact the growth and development of the baby.This study evaluated the effect of maternal sleep quality with newborn health. The research design was a cross-sectional study.The sample of this study were mothers who gave birth by cesarean delivery method with gestational age ≥ 37 weeks without complications, totally 78 pregnant women. The maternal sleep quality were assessed by PSQI questionnaire. Newborn Health (neonatal birth weight, body length and APGAR SCORE) were assessed by neonatal medical record. BDNF levels checked using the ELISA. Data were analyzed by Independent T-test and Mann-Whitney Test. There was no significant association between Maternal Sleep Quality with neonatal birth weight (p= 0,177).There were significant association between Maternal sleep quality with body length and APGAR SCORE of neonates with p value <0.05 (p = 0.025)(p=0,002). There was also a significant relationship between maternal sleep quality and neonatal cord blood BDNF levels (p=0.00). Sleep disturbances can impact obstetric conditions and newborn health. In this study there was no significant relationship between maternal sleep quality with neonatal birth weight.
Hubungan Status Gizi dengan Kejadian Hiperemesis Gravidarum Alfin Rahma Fadhilah; Delmi Sulastri; Hudila Rifa Karmia
Jurnal Ilmu Kesehatan Indonesia Vol 3 No 3 (2022): September 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v3i3.643

Abstract

Latar Belakang: Hiperemesis gravidarum adalah mual dan muntah berlebihan yang terjadi pada ibu hamil muda, yang dapat memengaruhi keadaan umum dan mengganggu aktivitas sehari-hari. Penyebab terjadinya hiperemesis gravidarum belum diketahui secara pasti, namun status gizi merupakan salah satu faktor risiko yang dapat dimodifikasi dan sering dihubungkan dengan kejadian hiperemesis gravidarum. Objektif: Mengetahui hubungan status gizi dengan kejadian hiperemesis gravidarum. Metode: Penelitian ini merupakan penelitian analitik retrospektif dengan pendekatan case-control. Sampel pada penelitian ini terdiri atas 23 sampel kasus dan 23 sampel kontrol dengan teknik pengambilan sampel kasus yaitu secara total sampling dan sampel kontrol secara systematic random sampling, kemudian data dianalisis dengan menggunakan uji Chi Square. Hasil: pada penelitian ini didapatkan 39,1% kelompok kasus memiliki status gizi normal dan 78,3% kelompok kontrol memiliki status gizi normal. Pada uji Chi Square, menunjukkan terdapat hubungan yang bermakna antara status gizi dengan kejadian hiperemesis gravidarum (p=0,007, OR=5,600). Kesimpulan: terdapat hubungan yang bermakna antara status gizi dengan kejadian hiperemesis gravidarum.
The Role Of Vitamin D And Calcium In Pre-Eclampsia And The Association With Neonatal Outcomes Tara Fadila; Yusrawati Yusrawati; Hudila Rifa Karmia
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.253-266.2023

Abstract

Introduction: Pre-eclampsia is one of the main causes of maternal and neonatal death in developingcountries. A low vitamin D level can increase the risk of neonatal abnormalities. Clinical studiesreported various complications of low vitamin D levels, such as pre-eclampsia, gestational diabetes,low birthweight, and caesarean section. This study aimed to investigate the role of vitamin D inpregnancy with pre-eclampsia and its association with neonatal outcomes.Methods: This is an observational analytical study uses a cross-sectional approach to investigatevitamin D levels and pre-eclampsia, conducted in General Hospital Dr. M. Djamil Padang from Mei2021 – April 2022. A total of 5 mL blood was withdrawn to analyzed vitamin D. This study has beenapproved by Health Research Ethics Committee Andalas University (Approved number:339/KEPK/2021).Results: There was a significant difference in the levels of 1,25 dihydroxy vitamin D3 between normalpregnancy and pre-eclampsia patients (99,18 vs 72,53 pg/ml; p = 0,033). In the pre-eclampsia patients’first APGAR score, there was a significant difference in the levels of 1,25 dihydroxy vitamin D3 betweennormal, moderate, and severe asphyxia groups (114,19 vs 66,75 vs 74,78 pg/ml; p = 0,025).Conclusion: Measuring early maternal 1,25 dihydroxy vitamin D3 can lower the pre-eclampsia risksand the impact the perinatal outcomes, particularly in determining first Apgar scores.
Co-Authors Abdiana Abdiana, Abdiana Afriwardi Afriwardi Alfin Rahma Fadhilah Alvarino Amel Yanis Annisa Namirah Nasution Asti Marian Sari Bobby Indra Utama Defrin Defrin Delmi Sulastri Desmawati Desmawati Dina Arfiani Rusjdi Eti Yerizel Hafidz Aryan Abdillah Hafni Bachtiar Hirowati Ali Iria Ningsih Busri Izmi Fadhilah Nasution Johanes C. Mose Joserizal Serudji Muhammad Iqbal Muhammad Iqbal Nur Afrainin Syah Rahmi Andrita Yuda Reyhan Julio azwan Reyhan Julio Azwan Rinang Mariko Syammel Muhammad Tara Fadhillah Tara Fadila Ulya Uti Fasrini Vaulinne Basyir Wiyola Audina Yusrawati Yusrawati Yusri Diannne Jurnalis