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The Effect of Body Mass Index on Five Years Progression Free Survival in Breast Cancer Wiwiek Probowati; Tejo Jayadi; brenda miriane rustam; agatha maheswari adita putri
Berkala Ilmiah Kedokteran Duta Wacana Vol. 7 No. 2 (2022): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v7i2.473

Abstract

Backgroud Breast cancer is the type of cancer that has the highest prevalence. Breast cancer growth is related to nutritional status. Nutritional status is assessed based on measurements of BMI Body Mass Index (BMI) and obesity is a factor that plays a role in the growth of cancer cells.Objective To investigate the effect of BMI on the five-year progression-free survival (PFS) of breast cancer patientsMethods A retrospective cohort study using observational methods on 82 female patients with breast cancer at Bethesda Hospital, Yogyakarta.Results A total of 82 medical records of breast cancer patients were collected at Bethesda Hospital Yogyakarta. A total of 71 patients (86.6%) were still alive, while 11 have died. This study found an average progression-free survival of BMI category <25 kg/m2 78,5 months while the BMI ≥ 25.0 kg/m² 80,9 months (HR 2,057, 95% CI: .457–2.491). In addition, BMI and other prognostic variables did not have a significant relationship with progression-free survival in breast cancer patients (p = 0.114).Conclusion In this study, Body Mass Index was not associated with the 5-year progression-free survival of breast cancer patients. 
EDITORIAL Role of Obesity in Breast Cancer Metastasis and Relapse Tejo Jayadi
Berkala Ilmiah Kedokteran Duta Wacana Vol. 7 No. 2 (2022): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v7i2.576

Abstract

The breast cancer patients survivors expected to be increased, because of better early cancer detection and better treatment. Although the survivorship should be celebrated, but there are common late effect of cancer and its treatment. So, it need to be better health care treatment provided to the survivor to give them better quality of life.
Hubungan antara Obesitas dengan Kanker Ovarium di Rumah Sakit Bethesda Yogyakarta Anglicia Lovelin Handoko; Tejo Jayadi; Eduardus Raditya Kusuma Putra; Theresia Avilla Ririel Kusumosih
Jurnal Kedokteran Meditek Vol 29 No 1 (2023): JANUARI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v29i1.2544

Abstract

Kanker ovarium merupakan keganasan yang terjadi pada organ ovarium. Gambaran yang umum terlihat adalah gambaran sel invasif, merusak struktur disekitarnya, dan dapat bermetastasis. Penyebab kanker ovarium bersifat multifaktoral, seperti faktor genetik, riwayat penyakit kanker, riwayat kehamilan, dan lain-lain. Obesitas menjadi salah satu faktor risiko kanker ovarium. Pada wanita obesitas, dapat terjadi peningkatan risiko terkena kanker ovarium 10% lebih tinggi dibandingkan wanita dengan IMT normal. Peningkatan lemak berlebihan dapat menyebabkan perubahan hormonal dan terjadinya inflamasi berkepanjangan sehingga mempermudah kanker berkembang. Melalui tulisan ini, akan dibahas lebih dalam mengenai hubungan antara obesitas dengan kanker ovarium di Rumah Sakit Bethesda Yogyakarta. Data yang digunakan adalah data sekunder berupa rekam medik pasien tumor jinak ovarium dan kanker ovarium di Rumah Sakit Bethesda Yogyakarta tahun 2015-2019. Penelitian menggunakan desain cross-sectional dan sampel terbagi menjadi 2, yaitu penderita kanker ovarium dan penderita tumor jinak ovarium. Pengambilan sampel menggunakan metode random sampling dan total terdapat 118 data yang digunakan. Data dianalisis menggunakan uji chi-square dengan nilai p 0,335 (p >0,05) yang berarti hasil dari penelitian ini menunjukkan bahwa obesitas tidak memiliki hubungan yang signifikan dengan kasus kanker ovarium di Rumah Sakit Bethesda Yogyakarta.
BAKTI SOSIAL SEBAGAI UPAYA PENCEGAHAN PENYAKIT TIDAK MENULAR DI BANTENG, YOGYAKARTA Wiwiek Probowati; Tejo Jayadi; Matahari Bunga Indonesia; Maria Agustina; Bernadeta Amaya Wakitaningtyas
Servirisma Vol. 4 No. 1 (2024): Servirisma : Jurnal Pengabdian kepada Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/servirisma.2024.41.68

Abstract

Social service activities are held with free health checks such as blood sugar, cholesterol and uric acid. Social service is carried out to assist with initial screening to prevent non-communicable diseases which are the leading cause of death in Indonesia. Activities were carried out in the villages of Banteng, Ngaglik, Sleman, Yogyakarta and residents of the GKJ Dayu congregation. The method of service is to carry out an assessment of the target area and coordinate with GKJ Dayu, the Head of Banteng Village and the formation of a Service Team from the Faculty of Medicine, Duta Wacana Christian University. Evaluation of social service activities is carried out qualitatively by means of discussion and quantitatively by looking at data on participants who registered whether they were successful through screening or not successful through screening. This social service activity was attended by 70 participants who took part in general examinations and were further divided into 5 people undergoing IVA examinations, 5 people undergoing health consultations and 54 people undergoing simple laboratory examinations. From the results of this social service it can be concluded that this activity succeeded in making a real contribution to social service participants who needed free examinations and was able to empower the community by increasing knowledge about non-communicable disease health.
Hubungan Sosiodemografi dan Klinikopatologi dengan Ketahanan Hidup Pasien Kanker Payudara Jayadi Tejo
Jurnal Biomedika dan Kesehatan Vol 5 No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.33-41

Abstract

Background: The research of breast cancer prognostic factors has been conducting for a long time, but the results still controversial. The research on demography and clinicopathology factors that determine the survival of breast cancer (BC) patients, remains to be done. Methods: The observational analytic with cross-sectional design would be conduct to describe the demographic, clinicopathology, therapy and two years survival of breast cancer patients. The independent variables were age, stage of disease, and molecular subtype. The dependent variable was two years survival. The association between those variables analyzed by bivariate statistic and the significant variables would be analyzed by regression logistic. Results: Most age of breast cancer patients at diagnosis were ≥ 50 years (74.5%). The majority of sociodemographic profiles of BC patients were undergraduate education, private job and married. The main histological type was the invasive ductal carcinoma. More than 50% of the patients were high stage (60.8%) and hormonal receptors molecular subtype (60.7%). Neoadjuvant chemotherapy was given to 40 patients (78.5%), only 9 patients (17.7%) eligible for anti HER-2/neu therapy. There were 42 of patients (82.4%) have two years survival. There weren’t association between age (p=0.586), stage of disease (p=0.223), molecular subtype (p=0.223) with two years survival of breast cancer patients. Conclusions: The common risk factors of breast cancer is increasing age. Most of breast cancer patients presenting high stage and hormone receptors positive of BC. Although there weren’t significance association, the prevalence low stage BC patients had higher two years survival.
Efektivitas Terapi Metformin dalam Mencapai Target Kadar HbA1c Ni Kadek Ayu Kunti Pertiwi; Lisa Kurnia Sari; Hendi Wicaksono; Tejo Jayadi
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 4 (2025): Oktober 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i4.6349

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease with high prevalence in Indonesia, include Bantul Regency,Yogyakarta. In September 2024 the number of cases reached 18,520, indicating a high disease burden at the primary healthcare level. At Puskesmas Imogiri 1, most T2DM patients receive metformin therapy, yet the coverage of care and effectiveness of treatment in achieving optimal glycemic control, particularly HbA1c levels, remain challenging in daily practice. This study aimed to assess the effectiveness of metformin dosage in achieving HbA1c <7% in T2DM patients at Puskesmas Imogiri 1. A quantitative study with a cross-sectional design and total sampling technique was conducted among T2DM patients treated at this facility. The variables studied included type and dosage of metformin therapy and HbA1c levels as indicators of glycemic control, with data collected from medical record reviews, including medication history and the most recent HbA1c test results. Of the 54 respondents, 35.2% achieved HbA1c <7%, while the majority remained above the target. Statistical analysis using Fisher’s Exact Test revealed no significant association between metformin dosage and glycemic control status. Likewise, duration of therapy, sex, and age were not significantly associated with HbA1c achievement (p>0.05). In conclusion, this study indicates that there is no significant relationship between metformin dosage, duration of therapy, age, or sex and the achievement of HbA1c targets in T2DM patients at Puskesmas Imogiri 1.