Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

0.444

P-Index

This Author published in this journals

All Journal HAYATI Journal of Biosciences Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Journal of Community Empowerment for Health Cermin Dunia Kedokteran Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal)

Irwan Supriyanto

Bagian Ilmu Kedokteran Jiwa Fakultas Kedokteran Universitas Gadjah Mada / RSUP Dr. Sardjito, Yogyakarta, Indonesia

Author-ID : 2421126

Agriculture, Biological Sciences & Forestry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 7 Documents Claim Missing Document

Claim Missing Document

Articles

The Banana (Musa balbisiana Colla) Peels Flour Modulates HTR2B Receptor Expression in the Liver Diabetic Rats Andreanyta Meliala; Paramita Narwidina; Herlin Ajeng Nurrahma; Irwan Supriyanto
HAYATI Journal of Biosciences Vol. 29 No. 3 (2022): May 2022
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.29.3.279-287

Uncontrolled diabetes mellitus (DM) has been linked to depression and lipid metabolism impairment. Serotonin (5-HT) has been known to improve lipid metabolism and affect mood. The 5-Hydroxytryptophan (5-HTP) in banana peel flour (BPF) is a precursor to synthesize 5-HT in the body, which is linked to initiating liver regeneration via HTR2B receptors. The impact of 5-HTP in the diet on HTR2B receptor expression has yet to be thoroughly investigated. We aimed to elucidate the correlation between serum lipid profile and immobility time in Tail Suspension Test (TST) as depressive-like behavior and compare the expression of HTR2B receptor in healthy and diabetic rats. Male Wistar (Rattus norvegicus) rats were assigned to the control and treatment groups in a DM model with streptozotocin (60 mg/kg) injected intraperitoneally, then either fed standard diet or BPF 10% supplemented standard diet for 21 days. Immunohistochemical staining was used to examine the expression of 5-HT, HTR2B receptors. We determined that diabetic rats fed the standard diet supplemented 10% BPF group showed significantly lower concentrations of total cholesterol and triglycerides compared to diabetic rats fed a standard diet and it was positively correlated between total cholesterol and LDL with the duration of immobility time in TST. The average immunoreactivity score in diabetic rats fed 10% BPF was the highest among the other groups, indicating that the available BPF dose is sufficient for HTR2B activation, which will support the liver cell regeneration process, and should be investigated further.

Minnesota Multiphasic Personality Inventory 2 (MMPI 2) examination in patients with benzodiazepine addiction in Yogyakarta Silas Henry Ismanto; Irwan Supriyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 47, No 3 (2015)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Addiction is a major health problem in Indonesia. The prevalence and pattern of drugsaddiction shifted according to changes in personality, stressors, or increasing responsibilityas people grow. Individual personality will affect their tendency to develop drug addiction.Benzodiazepines abuse has steadily increased. Unlike other type drugs of abuse, thecharacteristics of benzodiazepine abusers are greatly varied. Therefore, the personalitytraits and social economic factors involved in the benzodiazepine addiction are unique.In this study we evaluated the personality traits of patient with benzodiazepine addictionin Yogyakarta using Minnesota Multiphasic Personality Inventory (MMPI) 2 test. Thisstudy was a descriptive analytic study with a cross sectional design. Subjects were 39benzodiazepine addicts obtained from private psychiatrist practices in Yogyakarta. Theinstruments used were questionnaire for personal information and MMPI 2. Statisticalanalysis was conducted with SPSS ver. 17 and significance level was defined at p<0.05.MMPI 2 test revealed a low total mental capacity index and a low basic personality index(OCEAN: openness, conscientiousness, extraversion, agreeableness, and neuroticism).The clinical profiles examination showed profile of somatic symptoms due to psychologicaldisturbances, clinical symptoms of overt suspiciousness, overt negative emotionality,clinical symptoms of depression, symptoms of psychopathic behaviours (antisocial),emotional difficulty in interpersonal relationship, clinical symptoms related to overtemotion, and weird and bizarre psychological experiences. There are certain personalityvariables that may be important predictors for benzodiazepine addiction identified in thisstudy.

Impulsivity and novel object recognition test of rat model for vascular cognitive impairment after antipsychotics treatment Ronny T Wirasto; Irwan Supriyanto; Arif Prassetyo; Nunu N Madjid; Susini R Sari; Baiq R Rhadianaa; Heru Yulianto; Nur Arfian; Nyoman Kertia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 48, No 3 (2016)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

ABSTRACTVascular cognitive impairment (VCI) is a common condition in which no standard treatment has been approved. VCI is often accompanied by behavioral problems which require psychiatric interventions. The common therapeutic agent used for the acute management is antipsychotic injections. Current findings showed that atypical antipsychotic possess better safety profile for treating behavioral problems related to VCI compared to typical antipsychotic. In this study, we induced VCI in Sprague Dawley rats between 6-8 weeks old using bilateral carotid communist artery occlusion technique. The subjects were divided into 4 treatment groups: sham, olanzapine, haloperidol, and risperidone groups. Subjects received intramuscular injections of subsequent drugs for 3 days post VCI induction. Impulsive behavior and object recognition were examined using cliff jumping test and novel object recognition test. The analyses results showed that impulsive behavior was lower in the olanzapine and haloperidol groups compared to sham group, although it was not statistically significant (p = 0.651). The results also showed that there were no significant differences in the time spent exploring old and novel objects in all groups (p = 0.945;0.637 respectively). In conclusion, antipsychotic injection might not be effective to control impulsive behavior post VCI induction.

Hubungan Karakteristik Responden dan Dukungan Sosial dengan Kecemasan pada Remaja Pasca 7 Tahun Erupsi Gunung Merapi Rizki Muthia Putri; Sri Hartini; Fitri Haryanti; Irwan Supriyanto
Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal) Vol 2, No 1 (2018)
Publisher : PSIK FKKMK UGM

Background: The 2010 Mount Merapi eruption was the biggest in the last 100 years, and had caused various impact. Anxiety is one of the psychological problems often arise in adolescent after disaster. Anxiety post-disaster in adolescent are affected by gender, age, loss of nearest person, and social support.Objective: To know the relationship between respondent characteristic and social support with anxiety in adolescent, and description of anxiety in adolescent after 7 years eruption of Mount Merapi in Wukirsari permanent residence village.Research Methods: This research was a descriptive analytic with cross-sectional design and quantitative approach. This research was conducted in January 2018. The sample used was 50 adolescents who live in Wukirsari permanent residence village. Data collect used Revised Children Manifest Anxiety Scale (RCMAS) for anxiety and The Multidimensional Scale of Perceived Social Support (MSPSS) for social support. Data analysis used was univariate analysis and bivariate analysis with independent sample t-test.Results: The result of data analysis were age, gender, education level, loss of the nearest person, and social support with anxiety had p value respectively 0,440; 0,801; 0,158; 0,880; dan 0,690. The prevalence of anxiety in adolescent was 20% with symptoms that often arise was worry-oversensitivity, after 7 years eruption of Mount Merapi.Conclusion: There is no relationship between age, gender, education level, loss of the nearest person, and social support with anxiety in adolescent after 7 years eruption of Mount Merapi in Wukirsari permanent residence village. ABSTRAKLatar Belakang: Erupsi Gunung Merapi pada tahun 2010 merupakan erupsi terbesar yang terjadi dalam kurun waktu 100 tahun terakhir dan menimbulkan berbagai dampak pada kesehatan fisik maupun psikologis. Kecemasan merupakan salah satu dari masalah psikologis yang sering timbul pada remaja setelah terjadi bencana. Kejadian kecemasan pada remaja pascabencana dipengaruhi oleh usia, jenis kelamin, kehilangan orang terdekat, dan dukungan sosial.Tujuan: Mengetahui gambaran kecemasan remaja setelah 7 tahun erupsi Gunung Merapi serta hubungan antara karakteristik responden dan dukungan sosial dengan kecemasan pada remaja di hunian tetap (huntap) Wukirsari.Metode: Penelitian ini merupakan penelitian deskriptif analitik, menggunakan pendekatan kuantitatif, dengan rancangan cross sectional. Penelitian ini dilakukan pada bulan Januari 2018. Besar sampel yang digunakan yaitu 50 remaja yang tinggal di huntap Wukirsari. Kuesioner Revised Children Manifest Anxiety Scale (RCMAS) digunakan untuk mengukur kecemasan dan The Multidimensional Scale of Perceived Social Support (MSPSS) digunakan untuk mengukur dukungan sosial. Data dianalisis menggunakan analisis univariat dan analisis bivariat dengan uji independent sample t-test.Hasil: Prevalensi remaja yang mengalami kecemasan setelah 7 tahun erupsi Gunung Merapi yaitu 20% dengan gejala yang sering muncul yaitu worry-oversensitivity. Hasil analisis data antara usia, jenis kelamin, tingkat pendidikan, kehilangan orang terdekat, dan dukungan sosial dengan kecemasan memiliki nilai p berturut-turut 0,440; 0,801; 0,158; 0,880; dan 0,690.Kesimpulan: Tidak ada hubungan antara usia, jenis kelamin, tingkat pendidikan, kehilangan orang terdekat, dan dukungan sosial dengan kecemasan remaja setelah 7 tahun erupsi Gunung Merapi.

Gambaran Kecenderungan Orthorexia Nervosa pada Mahasiswa Program Studi Kedokteran FK-KMK UGM Mutiara Anisha Zahra; Irwan Supriyanto; Sri Warsini
Jurnal Keperawatan Klinis dan Komunitas (Clinical and Community Nursing Journal) Vol 5, No 2 (2021)
Publisher : PSIK FKKMK UGM

Background: Orthorexia nervosa (ON) is a new psychological disorder that still needs further research. People living with ON have unsafe obsession with eating healthy food. Research related to ON among graduate students in Indonesia, especially medical students, has not been done.Research Objectives: This study aims to determine the proportion of orthorexia nervosa (ON) tendency and to investigate certain characteristics that might influence ON tendency among medical students at FK-KMK UGM.Methodology: This research was a descriptive study with a cross-sectional design. Data collection took place in October-November 2019. Respondents involved were 97 students. The instrument used was ORTO-15. The results were analysed with Chi-Square Test and Fisher Test.Results: The proportion of ON tendency among respondents was 44.3% (cut-off point 40) and there were significant relationship between ON tendency with the habit of respondents to access health related articles in web pages and social media.Conclusion: The ON tendency among medical students in FK-KMK UGM is relatively high with a prevalence percentage of 44.3%. Prevention efforts need to be made so that this trend does not develop into an actual health problem. ABSTRAKLatar Belakang: Orthorexia nervosa (ON) merupakan gangguan psikologis baru yang masih perlu banyak diteliti dengan ciri-ciri penderita memiliki obsesi berlebih terhadap pola makan yang dianggap sehat. Hingga saat ini penelitian terkait ON pada mahasiswa di Indonesia, khususnya mahasiswa kedokteran belum dilakukan.Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui proporsi kecenderungan orthorexia nervosa (ON) dan karakteristik responden yang memengaruhi kecenderungan ON pada mahasiswa Prodi Kedokteran FK-KMK UGM.Metodologi: Penelitian ini adalah penelitian deskriptif dengan desain cross-sectional. Pengambilan data berlangsung pada bulan Oktober-November tahun 2019. Responden yang terlibat sebanyak 97 mahasiswa. Instrumen yang digunakan adalah ORTO-15. Hasil analisa dilakukan dengan Chi-square dan Fisher test.Hasil: Proporsi kecenderungan ON pada responden adalah 44,3% (cut-off point 40). Ditemukan hubungan signifikan antara kecenderungan ON dengan kegemaran responden untuk mengakses laman berkaitan dengan kesehatan di sosial media (p<0,05).Kesimpulan: Kecenderungan ON pada mahasiswa kedokteran FK-KMK UGM tergolong tinggi. Perlu dilakukan upaya pencegahan agar kecenderungan ini tidak berkembang menjadi masalah kesehatan yang aktual.

Ganggguan Kognitif akibat Polusi Udara Ancaman bagi Generasi Mendatang Irwan Supriyanto
Cermin Dunia Kedokteran Vol 41, No 4 (2014): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v41i4.1151

Polusi udara merupakan masalah lingkungan yang sangat mungkin mempunyai dampak biologis. Paparan polusi udara dilaporkan mengganggu perkembangan dan plastisitas sistem saraf pusat, terutama pada anak-anak. Polutan dapat merusak sistem saraf pusat melalui berbagai jalur inflamasi dan stres oksidatif, yang mengaktifkan mikroglia, sekresi berbagai faktor proinflamasi, mengakibatkan gangguan neurodegeneratif. Pajanan polutan kronik juga bisa merusak swar darah otak dan mengganggu homeostasis otak, selain dilaporkan mengganggu berbagai fungsi sistem saraf pusat dan menimbulkan gejala gangguan mental, terutama pada anak-anak yang sistem saraf pusatnya masih dalam masa perkembangan.Air pollution is an environmental problem with a possible biological consequence. It has been reported to disrupt central nervous system development and plasticity, particularly in children. Pollutant can damage central nervous system through inflammation and oxidative stress, which would activate microglia and induce the secretion of pro-inflammatory factors, resulting in neurodegenerative disorders. Chronic pollutant exposure might also disrupt the blood brain barrier and impair brain homeostasis; was also reported to disrupt numerous central nervous system functions and cause mental symptoms, especially in children with developing brain.

Association of religious coping use with psychological well-being of mother of mentally retarded children Sak Liung; Carla Raymondalexas Marchira; Irwan Supriyanto; Mahar Agusno; Soewadi Soewadi; Sumarni Sumarni
Journal of Community Empowerment for Health Vol 2, No 2 (2019)
Publisher : Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

Low psychological well-being in mothers of children with mental retardation can affect maternal mental health and quality of life. Psychological well-being of mothers depend on maternal coping strategies to overcome the burden of childcare. The religious background of Indonesian society makes mothers tend to use religious coping in handling the burden of nurturing their children. Aim of this study to determine the association between religious coping use and psychological well-being of mothers of children with mental retardation. This is an analytic descriptive study with cross-sectional design. Subjects were mothers of children with mild to moderate level of mental retardation, students of SLB Negeri 1 Bantul. The psychological well-being and religious coping of mother is assessed by Indonesian version of the Psychological Well-being Scale and Religious Coping Scale. The significance level of the statistical test is expressed at p < 0.05. Results of this study showed there is a significant association between religious coping and psychological well-being of mothers of children with mental retardation (X2: 17.897; C: 0.377; p: 0.000; RP: 5.65; 95% CI: 2.46-12.92). All dimensions of religious coping have a significant association with the psychological well-being of the mother (p: 0.000). The dimensions of achieving comfort and closeness to God have the highest closeness association with the psychological well-being among other dimensions of religious coping (X2: 39.041; C: 0.515). The confounding variables in this study are mother’s age, mother’s education, family income, marital status, mother’s employment status, family income, children’s gender, children's level of mental retardation and children’s class grade. Mother’s education has also a significant association with the psychological well-being of the mother (p: 0.021). Religious coping and mother’s education contribute 26.7% to the psychological well-being of mothers. This finding reveals that religious coping is important to improve the psychological well-being of mothers of children with mental retardation.

Co-Authors Arif Prassetyo Baiq R Rhadianaa Carla Raymondalexas Marchira Fitri Haryanti Heru Yulianto Mahar Agusno Meliala, Andreanyta Mutiara Anisha Zahra Nunu N Madjid Nur Arfian Nurrahma, Herlin Ajeng Nyoman Kertia Paramita Narwidina Rizki Muthia Putri Ronny T Wirasto Sak Liung Silas Henry Ismanto Soewadi Soewadi Sri Hartini Sri Warsini Sumarni Sumarni Susini R Sari

Title

Found 7 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 7 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 7 Documents
Search