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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Indian Journal of Forensic Medicine & Toxicology Bali Dermatology Venereology and Aesthetic Journal
Maylita Sari
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The Effect of Amniotic Membrane Stem Cell Metabolite Product (AMSP-MP) Combine with Vitamin E after Microneedling in Photoaging Progress Cita Rosita Sigit Prakoeswa; Agatha Anindhita Ayu Ardhaninggar; Riyana Noor Oktaviyanti; Irmadita Citrashanty; Maylita Sari; Menul Ayu Umborowati; Dwi Murtiastutik
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14695

Abstract

Introduction: The photoaging is a cumulative process. Amniotic Membrane Stem Cell Metabolite Products(AMSC-MP) that contain cytokines and growth factors that have a role in the skin’s rejuvenation process.Vitamin E is an antioxidant that has a photoprotective effect. Topical combination of AMSC-MP and VitaminE are expected to have an effect on clinical photoaging improvement.Objective: To evaluate the effect of topical combination of AMSC-MP with vitamin E after microneedlingcompared with AMSC metabolite products after microneedling.Methods: A total 60 photoaging women were included in this experimental analytic, controlled, matchingresearch. Each participant’s face was allocated to topical combination of AMSC-MP and vitamin E inintervention group and AMSC-MP only in control group. Microneedling modality was use to enhanceepidermal penetration. Three treatment sessions were repeated at two weeks’ interval.Results: From the comparison of the two groups showed there were significant different of mean value inwrinkle, skin tone and UV spots with p-value < 0,005 in the intervention grup. While pore and polarized spotdo not show significant differences between two groups.Conclusion: The administration of a topical combination of MP-AMSC and vitamin E after microneedlingprovides clinical improvement in photoaging.
Gambaran Histopatologi Nekrobiosis Lipoidika Maylita Sari; Trisniartami Setyaningrum; Willy Sandhika
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 26 No. 1 (2014): BIKKK APRIL 2014
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1210.161 KB) | DOI: 10.20473/bikk.V26.1.2014.1-8

Abstract

Latar belakang: Nekrobiosis Lipoidika (NL) merupakan keadaan dermatologis idiopatik yang menjadi masalah secara kosmetik dan berhubungan erat dengan penyakit diabetes mellitus. Pemahaman tentang patogenesis dan diagnosis NL sangat penting karena adanya komplikasi yang bisa terjadi seperti ulserasi dan karsinoma sel skuamosa, disamping kesulitan penegakan diagnosis NL melalui histopatologi. Tujuan: Memahami patofisiologi, gambaran klinis, dan histopatologi NL serta diagnosis banding granuloma non infeksi. Telaah kepustakaan: Perubahan vaskular dan degenerasi kolagen serta faktor lain adanya Antibody Mediated Vasculitis diduga terjadi pada patogenesis NL. Prinsipnya didapatkan kerusakan mikrosirkulasi pada individu non diabetik dengan NL. Pemeriksaan histopatologi menunjukkan terdapat granuloma interstitial dan palisade yang melibatkan jaringan subkutan dan dermis. Granuloma tersusun berlapis-lapis (tierlike, layered) dan bercampur dengan area degenerasi kolagen, terdiri dari histiosit, beberapa diantaranya limfosit berinti banyak, sel plasma, dan eosinofil. Penebalan dinding pembuluh darah dan pembengkakan sel endotel pada dermis bagian tengah sampai dalam. Imunofluoresens direk didapatkan immunoglobulin M, Ig A, C3, dan fibrinogen pada pembuluh darah. Manifestasi klinis ditandai dengan plak berbatas jelas dengan area atrofi kekuningan pada tengahnya dan tepi menonjol berwarna merah sampai ungu, yang bisa mengalami ulserasi, bilateral, dan multipel. kesimpulan: NL merupakan suatu penyakit degeneratif kronis pada jaringan konektif dermis, dengan etiologi yang tidak diketahui dan terjadi hampir seluruhnya pada penderita diabetes mellitus. Diagnosis ditegakkan secara klinis dan histopatologi. Gambaran histologi NL hampir sama dengan granuloma annulare, namun manifestasi klinis berbeda.Kata kunci: nekrobiosis lipoidika, diabetes melitus, histopatologi, granuloma.
A successfully treated Basal Cell Carcinoma using elliptical excision surgery Irmadita Citrashanty; Hamidah Luthfidyaningrum; Evy Ervianti; Bagus Haryo Kusumaputra; Maylita Sari; Muhammad Yulianto Listiawan; Yoana Fransiska Wahyuning Christi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 1 (2023): Qanun Medika Vol 07 No 01 January 2023
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i1.15384

Abstract

 Basal cell carcinoma (BCC) is a non-keratinization cell-derived neoplasm. Surgical excision is the most common way to remove a tumor. The excision depends on the tumor type, size, and location. This paper reported a 44- years-old woman presented with the chief complaint of a single bump that bleeds easily in the facial region that began one year ago. Dermatology examination revealed hyperpigmented plaque with an ulcer in central, solitary, oval, 2 cm x 1 cm in size, covered with blackish crust on top. A Dermoscopy examination showed blue dots and globules, arborizing vessels, and ulceration. Histopathology examination findings were in concordance with BCC. The patient was treated with elliptical surgical excision. The lesion was successfully removed and showed good results with minimal scarring. BCC occurs in 75% of all skin cancers. Elliptical surgical excision on the left cheek was performed after considering the location anatomy, defect size, age, and general condition patient and postoperative cosmetic estimates. The minimal scar that occurs is planned to be performed with a fractional laser. The prognosis is generally good. There is no recurrence until one year later. In conclusion, elliptical surgical excision is an effective standard treatment if performed with a safe margin. In this case, we used 5 mm safe outer margin.
The Role of Topical Treatment on Vaginal Tightening Hendaria, Made Putri; Maylita Sari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.203-209

Abstract

Background: Physiological changes in a woman's life, such as labor, weight fluctuations, hormonal changes, aging, and menopause, cause changes in both appearance and function of the vagina. As estrogen deficiency continues, changes occur in the form of atrophy and dystrophy in the vaginal mucosa, vulva, and other structures in the urogenital tract which are called symptoms of vulvovaginal atrophy. It affects women's quality of life, self-confidence, and sexuality. As alternative modality for noninvasive therapy, topical therapy in vaginal rejuvenation is becoming available in the care of outpatients. This makes it increasingly important for dermatologists to be well-informed about these treatment options. Purpose: This review aims to assess the role of topical therapy in vaginal rejuvenation, especially in vulvovaginal atrophy cases. Literature Review: Vulvovaginal atrophy has a negative effect on interpersonal relationships, quality of life, daily activities, and sexual function. Topical hormone replacement therapy includes all preparations such as estradiol, estradiol valerate, or conjugated estrogen. considered in cases with vulvovaginal atrophy accompanied by atrophy of the urogenital system as well as the accompanying complaints because this therapy is intended to prevent systemic complications. The topical use of hyaluronic acid, lubricants, moisturizers, and herbs is a therapeutic choice in vulvovaginal atrophy patients contraindicated with estrogen therapy or in patients who do indeed choose nonhormonal therapy. Conclusion: Topical therapy of hormonal and non-hormonal rejuvenation in various studies has shown improvement in symptoms of vaginal dryness, vaginal itching, dyspareunia, cell maturity, and changes in vaginal pH toward acidity.
Mucocutaneous Manifestations in HIV/AIDS Patients Hidayati, Afif Nurul; Harningtyas, Citra Dwi; Damayanti, Damayanti; Astari, Linda; Indramaya, Diah Mira; Listiawan, M. Yulianto; Utomo, Budi; Budiono, Budiono; Murtiastutik, Dwi; Widyantari, Septiana; Maylita Sari; Astindari, Astindari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.156-161

Abstract

Background: The main target of human immunodeficiency virus (HIV) is cluster of differentiation 4 (CD4) T lymphocytes and several other immune cells that have CD4 receptors. They are also present in skin and mucosa, such as Langerhans cells (LC). Mucocutaneous lesions are one of the first clinical presentations of immunosuppression in HIV seropositive patients that manifest at different stages of the infection and require early diagnosis and prompt treatment. Purpose: To determine the clinical characteristics and the pattern of various mucocutaneous manifestations in Human immunodeficiency virus/Acquired immune deficiency syndrome (HIV/AIDS) patients at Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya. Methods: This is a descriptive retrospective study with a cross-sectional design. The study subject was classified as all HIV-AIDS patients with mucocutaneous manifestations treated in Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya in 2019. Result: Out of the 614 patients who participated in the study, 72.1% were males. The majority of patients were in the age group 25–49 years (75.4%). The most common risk factor was heterosexuality (41.7%). Based on the distribution of mucocutaneous manifestations, the most common mucocutaneous manifestation was candidiasis mucocutan 387 patients (49.4%) followed by the pruritic papular eruption (PPE) 118 patients (15.1%) and human papillomavirus infection 57 patients (7.3%). Conclusion: Mucocutaneous manifestations occur throughout the course of HIV infection, and they can be considered as good clinical indicators for the progression of the disease and underlying immune status in resource-poor settings.
A Retrospective Study of Demographic, Clinical, and Histopathological Profiles of Cutaneous Tumors Bintanjoyo, Lunardi; Hidayati, Afif Nurul; Cita Rosita Sigit Prakoeswa; Murtiastutik, Dwi; Bagus Haryo Kusumaputra; Listiawan, Muhammad Yulianto; Irmadita Citrashanty; Maylita Sari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 3 (2022): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.3.2022.149-155

Abstract

Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and  photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) and location on head and face (61.2%). Benign cutaneous tumors showed similar findings. Malignant cutaneous tumors showed differences including predominantly male sex, age above 45 years old, nodular, solitary, pigmented and easily bleeding lesions. Malignant tumors were less common (6.9%). Most common malignant tumor was BCC. Most common benign and overall cutaneous tumor was seborrheic keratosis. Conclusion: Cutaneous  tumors presented across gender and ages, showing heterogenous clinical manifestations. Malignant and benign cutaneous tumors showed similarity on time from onset and location of lesions. However, differences were seen in demographic profiles and majority of clinical features. BCC was the most common malignant cutaneous tumors, while seborrheic keratosis was the most common benign and overall cutaneous tumors.
Differences in the diagnosis of sweat gland tumors with other histopathologically similar skin tumors Maylita Sari; Arisia Fadila
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 5 No. 2 (December 2022)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/9jb27493

Abstract

Sweat gland tumors are still relatively rare compared to other skin tumors. The clinical features of sweat gland tumors are non-specific and are rarely encountered in daily diagnostic practice. This article aims to explain the features of benign sweat gland tumors based on clinical and histopathological features. Many sweat gland tumors have overlapping clinical features with other tumors, whether from other adnexal tumors or even malignant tumors. Fulton et al. divided eccrine and apocrine gland tumors into six groups based on the similarity of the basic histopathological features, which could help clinicians better establish benign sweat gland tumors. The histopathological examination could complement history taking and physical examination to establish benign sweat gland tumors.
Co-Authors Afif Nurul Hidayati, Afif Nurul Agatha Anindhita Ayu Ardhaninggar Arisia Fadila Astindari Astindari, Astindari Bagus Haryo Kusumaputra Bintanjoyo, Lunardi Budi Utomo Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Diah Mira Indramaya Dwi Murtiastutik Evy Ervianti Hamidah Luthfidyaningrum Harningtyas, Citra Dwi Irmadita Citrashanty Irmadita Citrashanty Linda Astari, Linda M. Yulianto Listiawan Made Putri Hendaria Menul Ayu Umborowati Riyana Noor Oktaviyanti Trisniartami Setyaningrum Widyantari, Septiana Willy Sandhika Yoana Fransiska Wahyuning Christi