Article Per Year (5 Year)
p-Index From 2020 - 2025
1.152
P-Index
This Author published in this journals
All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Bali Dermatology Venereology and Aesthetic Journal
Astindari Astindari, Astindari
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 9 Documents
Search

 1 
Cara Penularan HIV & AIDS Di Unit Perawatan Intermediate Penyakit Infeksi (UPIPI) RSUD Dr. Soetomo Surabaya Astindari, Astindari; Lumintang, Hans
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.29 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-5

Abstract

Latar belakang: Kasus HIV & AIDS makin lama makin meningkat. Sejak pertama kali dilaporkan pada tahun 1987 sampai 2009, di Indonesia tercatat 3.492 orang meninggal dunia karena penyakit ini. Cara penularan HIV & AIDS di Indonesia selalu mengalami perubahan. Awalnya cara penularan terjadi melalui hubungan heteroseksual. Kemudian peningkatan jumlah pengguna narkoba suntik (penasun) di Indonesia menyebabkan cara penularan HIV & AIDS juga mengalami perubahan karena penularan bisa terjadi melalui penggunaan jarum suntik bersama di kalangan para penasun. Saat ini cara penularan HIV & AIDS kembali lagi, terutama melalui hubungan heteroseksual. Perubahan cara penularan HIV & AIDS dari kelompok penasun ke heteroseksual mempengaruhi strategi pencegahan penularan HIV & AIDS di Indonesia, khususnya di RSUD Dr. Soetomo Surabaya. Tujuan: Mengevaluasi cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006-2010. Metode: Penelitian deskriptif, retrospektif tentang cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006 – 2010. Hasil: Kasus baru HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006-2010 didapatkan 3.090 kasus, dengan perbandingan pasien laki-laki lebih banyak dari pasien perempuan. Cara penularan tertinggi melalui hubungan seksual yaitu 63,5%, cara penularan berikutnya melalui penasun 24,8%, penasun + seksual 6,3%, dan perinatal 3,2%. Cara penularan melalui heteroseksual makin meningkat dari tahun 2006 sebanyak 186 orang (47,1%) menjadi 509 orang (71,9%) pada tahun 2010. Simpulan: Cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo mengalami perubahan, yang semula terbanyak melalui penasun pada tahun 2005 berubah melalui heteroseksual pada tahun 2010. Hal itu akan mempengaruhi strategi upaya pencegahan penyakit tersebut. Kata kunci: studi retrospektif, HIV & AIDS, penularan, heteroseksual, IDUs, penasun, perinatal.
Uji Difusi Sefiksim terhadap Neisseria gonorrhoeae pada Servisitis Gonore tanpa Komplikasi Astindari, Astindari; Lumintang,, Hans; Setyaningrum, Trisniartami
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.151 KB) | DOI: 10.20473/bikkk.V26.2.2014.1-5

Abstract

Latar belakang: Gonore merupakan salah satu infeksi menular seksual yang sering ditemukan. Resistensi terhadap beberapa antibiotik banyak ditemukan dalam beberapa tahun terakhir. Sefalosporin generasi ketiga seperti sefiksim dan seftriakson merupakan pilihan terapi lini pertama di berbagai negara, namun penurunan kepekaan sefiksim sudah ditemukan dan mulai menyebar. Tujuan: Mengevaluasi kepekaan sefiksim terhadap Neisseria gonorrhoeae secara difusi. Metode: Penelitian laboratorium yang bersifat deskriptif observasional, potong lintang mulai November 2012-Januari 2013. Terdapat 12 isolat N. gonorrhoeae dari 68 sekret serviks yang dilakukan uji kepekaan sefiksim secara difusi. Hasil: Uji kepekaan sefiksim secara difusi terhadap N. gonorrhoeae didapatkan 3 dari 12 isolat (25%) resisten terhadap sefiksim dan 9 dari 12 isolat (75%) sensitif terhadap sefiksim. Empat dari 9 isolat (44,5%) yang sensitif terhadap sefiksim mempunyai zona hambat dengan diameter 31 mm yang merupakan batas kemampuan sefiksim untuk menghambat pertumbuhan N. gonorrhoeae. Simpulan: Ditemukan strain N. gonorrhoeae yang menunjukkan, sehingga perlu dilakukan penelitian lebih lanjut berupa uji kepekaan secara dilusi untuk mengetahui adanya peningkatan resistensi N. gonorrhoeae terhadap sefiksim.Kata kunci: sefiksim, uji kepekaan secara difusi, N.gonorrhoeae.
Perbedaan Dermatitis Seboroik dan Psoriasis Vulgaris Berdasarkan Manifestasi Klinis dan Histopatologi Astindari, Astindari; Sawitri, Sawitri; Sandhika, Willy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.04 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-7

Abstract

Latar belakang: Dermatitis seboroik (DS) dan psoriasis sering sulit dibedakan baik secara klinis maupun secara histopatologi. Anamnesis yang tepat dengan memperhatikan usia, riwayat keluarga, dan pemeriksaan klinis yang teliti serta ditunjang dengan pemeriksaan histopatologi, dapat menentukan diagnosis yang tepat. Tujuan: Mengevaluasi perbedaan DS dan psoriasis supaya klinisi dan patolog bisa membuat diagnosis yang benar.Telaah kepustakaan: Secara epidemiologi, terdapat berbagai perbedaan antara DS dan psoriasis. Hal itu bisa dilihat dari usia saat timbulnya lesi, jenis kelamin, ras, maupun genetik. Lokasi lesi dan manifestasi klinis juga mempunyai ciri yang berbeda. Biopsi kulit dibutuhkan untuk membantu menegakkan diagnosis yang tepat.Gambaran histopatologi DS bervariasi sesuai dengan perjalanan penyakitnya: akut, sub-akut, dan kronis, sedangkan psoriasis mempunyai ciri khas berupa pemanjangan rete ridges, abses Munro atau adanya abses Kojog. Simpulan: Terdapat beberapa perbedaan antara DS dan psoriasis dari usia pertama kali muncul lesi, lokasi lesi, manifestasi klinis dan gambaran histopatologi.Kata kunci: dermatitis seboroik, psoriasis, manifestasi klinis, gambaran histopatologi.
Secondary Syphilis During Pregnancy: The Importance of Screening and Clinical Management Purnamasari, Indah; Barakbah, Jusuf; Martodiharjo, Sunarko; Murtiastutik, Dwi; Astindari, Astindari; Septiana, Septiana; Sari, Maylita; Hidayati, Afif Nurul
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.145-149

Abstract

Background: Syphilis is one of the most serious sexually transmitted diseases worldwide, and has tremendous consequences for the mother and her developing fetus if left untreated. The burden of morbidity and mortality due to congenital syphilis is high. Purpose: Screening and prompt to know the importance of treatment of syphilis during pregnancy. Case: A 32-year-old multigravida in 5 months of pregnancy presented with multiple raised lesions over her labia. It was accompanied by fluor and smelly fishy odor. There was no history of genital ulcers in either spouse and no history of sexual promiscuity. History of antenatal care in public health showed non-reactive status of HIV, syphilis and hepatitis B. Clinical examination revealed multiple flat, moist warts over her labia mayora and minora, and multiple roseola syphilitica on the plantar pedis sinistra. Darkfield microscopic examination presence spirochete, venereal disease research laboratory (VDRL) titer was 1:16 and T. pallidum particle agglutination assay (TPHA) titer was 1:2560. Obstetric ultrasonography examination was suggestive no mayor congenital abnormalities. Both of serology VDRL and TPHA were non-reactive in her husband. Significant of lesion improvement and decrease a fourfold titer serologic in VDRL (1:4) and TPHA (1:320) as follow-up 3 months after being treated with single intra-muscular injections of benzathine penicillin 2.4 million units. Discussion: Coordinated prenatal care and treatment are vital. It's implemented before the fourth month of pregnancy to reduce vertical transmission and all associated side effects of congenital syphilis. Penicillin is highly efficacious in maternal syphilis and prevention of congenital syphilis. Conclusion: Universal screening and adequate pregnancy care must be a priority.
Cutaneous Adverse Drug Reactions in Hospitalized HIV/AIDS Patients Wibisono, Yusuf; Agusni, Indropo; Hidayati, Afif Nurul; Rahmadewi, Rahmadewi; Astindari, Astindari; Septiana, Septiana; Sari, Maylita; Murtiastutik, Dwi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.96-102

Abstract

Background: Cutaneous adverse drug reaction (CADR) is the most common manifestation of drug hypersensitivity in humanimmunodeficiency virus (HIV), which presented as maculopapular rash. The incidence of CADR is found to be more commonin untreated HIV patients, and the frequency is higher in severe immunodeficiency status. Early diagnosis and appropriatetreatment give better outcomes. Purpose: To evaluate the incidence and management of CADR in HIV and acquired immunedeficiency syndrome (AIDS) patients. Methods: A retrospective descriptive study of HIV/AIDS patients with CADR whowere hospitalized at Intermediate Care and Infectious Disease Centre Dr. Soetomo General Academic Hospital. Result: Therewere more CADR cases in 2017, accounted 2.35% of the total Intermediate Care and Infectious Disease Centre RSUD Dr.Soetomo General Academic Teaching Hospital ward patients. There were more male patients (62.5%), with the mostcommonly found at the age of 25-44 years (64.3%), and which mostly (89.3%) originated from Surabaya. The most commondiagnosis was morbiliform eruption (60.7%), main complaint was red spots all over the body (45%), all of which are obscureerythematous macules. The most common causes were Duviral + Neviral antiretroviral (46%) and the most common treatmentwas dexamethasone injection. Conclusion: The incidence of CADR increased in 2017. The most frequent manifestation wasmorbilliform eruption due to Duviral+Neviral as the first line ARV treatment. Skin management varies widely in form oftopical, oral, and intravenous injection drugs, mostly using steroid class, dexamethasone intravenous injection in particular.
Mucocutaneous Manifestations in HIV/AIDS Patients Hidayati, Afif Nurul; Harningtyas, Citra Dwi; Damayanti, Damayanti; Astari, Linda; Indramaya, Diah Mira; Listiawan, M. Yulianto; Utomo, Budi; Budiono, Budiono; Murtiastutik, Dwi; Widyantari, Septiana; Maylita Sari; Astindari, Astindari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.156-161

Abstract

Background: The main target of human immunodeficiency virus (HIV) is cluster of differentiation 4 (CD4) T lymphocytes and several other immune cells that have CD4 receptors. They are also present in skin and mucosa, such as Langerhans cells (LC). Mucocutaneous lesions are one of the first clinical presentations of immunosuppression in HIV seropositive patients that manifest at different stages of the infection and require early diagnosis and prompt treatment. Purpose: To determine the clinical characteristics and the pattern of various mucocutaneous manifestations in Human immunodeficiency virus/Acquired immune deficiency syndrome (HIV/AIDS) patients at Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya. Methods: This is a descriptive retrospective study with a cross-sectional design. The study subject was classified as all HIV-AIDS patients with mucocutaneous manifestations treated in Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya in 2019. Result: Out of the 614 patients who participated in the study, 72.1% were males. The majority of patients were in the age group 25–49 years (75.4%). The most common risk factor was heterosexuality (41.7%). Based on the distribution of mucocutaneous manifestations, the most common mucocutaneous manifestation was candidiasis mucocutan 387 patients (49.4%) followed by the pruritic papular eruption (PPE) 118 patients (15.1%) and human papillomavirus infection 57 patients (7.3%). Conclusion: Mucocutaneous manifestations occur throughout the course of HIV infection, and they can be considered as good clinical indicators for the progression of the disease and underlying immune status in resource-poor settings.
A Rare Self-Limiting Adamantiades Behcet Diseasen in A Woman: A Case Report Fajrin, Farah Meriana; Damayanti; Hidayati, Afif Nurul; Murtiastutik, Dwi Murtiastutik; Astindari, Astindari; Widyantari, Septiana; Sari, Maylita
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.75-80

Abstract

Background: Adamantiades–Behçet is a genetically determined disorder with a probable environmental triggering factor and is an inflammatory disease representing vasculitis. Chronic relapsing progressive course, Dapson prevents problems in other organs. Case Report: A 31-year-old woman with chief complaints of a progressive painful ulcer on her genitalia in the last month, covered by pus and with a bad odor, and also recurrent tongue sores that healed spontaneously. Multiple partner sexual intercourse, joint pain, and an eye complaint were denied. Her husband has no history of previous sexually transmitted diseases. The labia majora region showed a solitary ulcer, sharply marginated, and covered with pus. The Haemophilus ducreyi, pathergy, VDRL, TPHA, and rapid test HIV all came back negative. Enterococcus faecalis, found in bacterial culture, is sensitive to Penicillin and glycopeptide. Histopathologically recited vasculitis with thrombus in the blood vessel marks Behcet disease. The patient was given Mefenamic Acid (3x500mg), doxycicline (2x100 mg), and a wet dressing. The ulcer decreased in size after 3 weeks of treatment. Discussion: Adamantiades-Behçett disease is characterized by chronic, recurrent oral aphthous ulcers, genital ulcers, skin lesions, ocular lesions, and arthritis or arthropathy. Viral and bacterial infections have been implicated in initiating immunopathologic pathways. The pathergy test is pathognomonic, but it is not specific and often gives a negative result. Histopathological examination is still the best option to establish the diagnosis. 
Profile of Disability in Leprosy Patients: A Retrospective Study Geani, Silvani; Rahmadewi, Rahmadewi; Astindari, Astindari; Sawitri, Sawitri; Ervianti, Evy; Utomo, Budi; Cita Rosita Sigit Prakoeswa; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.109-113

Abstract

Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae that affects peripheral nerves and skin. The interaction between M. leprae and Schwann cells causes irreversible damage to peripheral nervous tissue afterward disability occurs. Involvement of the major nervous trunks of the extremities can produce sensory-motor deficits. The risk factors are delay in diagnosis, gender, age, type of leprosy, duration of disease, number of affected nerves, leprosy reaction, type of treatment, socioeconomic factors, education, ethnicity, and occupation. Purpose: The aim was to study the profile of leprosy patients with disability who seek treatment in Leprosy Division Dermatovenerology Outpatient Clinic RSUD Dr. Soetomo Surabaya. Methods: This was a descriptive retrospective study of leprosy patients with disability from January 2017 to December 2019. Result: The results of this study obtained a total of 275 leprosy patients with disabilities, which consisted of 76 patients (27.6%) with grade-1 disability and 199 patients (72.4%) with grade-2 disability. The majority were male (73.4%) and aged 25-44 years old (42.2%). Other dominant risk factors were MB type leprosy (92%), duration of disease more than 12 months (52.3%), no leprosy reaction (68%), and had received multidrug therapy (45.5%). Conclusion: Knowledge of disability risk factors can assist in improving management and education to prevent disability in leprosy patients.
Large acrochordon of labium majora: an unusual location Citrashanty, Irmadita; Luthfidyaningrum, Hamidah; Murtiastutik, Dwi; Hidayati, Afif Nurul; Widyantari, Septiana; Astindari, Astindari; Sari, Maylita
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 1 (June 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/93p62v41

Abstract

Background: Acrochordon is a soft, round or oval, pedunculated papilloma that can be tan or brown in color. Although acrochordons most commonly appear in the neck, axilla, and groin, they can also appear in unusual sites, such as penis, vulva, and perineum. Most of the lesions are small pedunculated papules or nodules approximately 2–6 mm, but rarely, particularly on the lower section of the trunk, large pedunculated acrochordons can be found. Here we present a large acrochordon on the labium majora. Case Description: A 25 years old woman came to an outpatient clinic because there was a mass on her right labium majora ever since she gave birth three years prior. The size of the mass started off relatively small but has grown significantly over time. From dermatological examination in external genitalia region, there was a solitary, pedunculated, skin-colored mass measuring 10 × 3 cm, attached to right labium majora. There was no redness, ulceration, bleeding or discharge. Cautery excision with local anesthetic was performed to removed the mass. The histopathological examination of the specimen revealed polypoidal tissue lined by epidermal layer, there are proliferation and dilation of capillaries containing erythrocytes in the dermis layer, mild infiltration of lymphocytes and histiocytes. No evidence of malignancy. Conclusion: We report an unusual location of acrochordon presenting with large size. Due to its atypical presentation, it may be confused with a malignancy, necessitating a pathological test. Total excision of the mass is recommended.
Co-Authors Afif Nurul Hidayati, Afif Nurul Budi Utomo Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Diah Mira Indramaya Dwi Murtiastutik Evy Ervianti Fajrin, Farah Meriana Geani, Silvani Hans Lumintang, Hans Hans Lumintang,, Hans Harningtyas, Citra Dwi Indah Purnamasari INDROPO AGUSNI Irmadita Citrashanty, Irmadita Jusuf Barakbah, Jusuf Linda Astari, Linda Luthfidyaningrum, Hamidah M. Yulianto Listiawan Martodiharjo, Sunarko Maylita Sari Maylita Sari, Maylita Rahmadewi Rahmadewi Sawitri Sawitri SEPTIANA SEPTIANA Trisniartami Setyaningrum Widyantari, Septiana Willy Sandhika Yusuf Wibisono