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PENGARUH PEMBERIAN EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) LAMPUNG TERHADAP JUMLAH SEL PURKINJE CEREBELLUM TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR Sprague dawley YANG DIINDUKSI MONOSODIUM GLUTAMAT Ilham Nugroho; Anggraeni Janar Wulan; TA Larasati; Khairun Nisa Berawi
MAJORITY Vol 11 No 2 (2023): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Excessive consumption of monosodium glutamate has a neurotoxic effect on the brain, one of which is the cerebellum. The caffeine and chlorogenic acid compounds contained in coffee beans have potential as an anti-inflammatory and neuroprotective agent thus protecting rats from neurotoxicity by glutamate involved with the death of cerebellar purkinje cells. This research is an experimental study with Completely Randomized Design (CRD) with a Posttest Only Control Group Design approach. The research subjects were 25 rats which were divided into 5 groups which are K- (aquadest 3,5 ml/day), K+ (MSG 4 g/kgBW/day), P1, P2, P3 (MSG 4 g/kgBW/day and robusta coffee extract lampung 1,5 ml/200gBW/day with a concentration of 0,03 g/ml; 0,06 g/ml; 0,12 g/ml respectively) with each group consisting of 5 rats. The number of purkinje cells is calculated by manual counting assisted by Image J software in 3 sections with 5 visual fields each in 400x magnification. The average number of cerebellar purkinje cells in K-, K+, P1, P2, and P3 were 22,72; 11,88; 22,44; 25,28; 27,12 respectively. One Way ANOVA test obtained p value=0,000 (p<0,05). Post Hoc LSD test on the number of purkinje cells showed a significant differences (p<0,05) between K- and K+ (p=0,000), K- and P3 (p=0,006), K+ and P1 (p=0,000), K+ and P2 (p=0,000), K+ and P3 (p=0,000), and P1 and P3 (p=0,004). There is an effect of robusta coffee extract (Coffea canephora) lampung againsts to the number of cerebellar purkinje cells in male rats strain (Rattus norvegicus) Sprague dawley induced by monosodium glutamate.
Ownership Of The Right To An Apartment Unit By A Foreign Citizen After The Enactment Of The Job Creation Law Ilham Nugroho; Imam Koeswahyono; Hanif Nur Widhiyanti
International Journal Of Humanities Education and Social Sciences (IJHESS) Vol 4 No 1 (2024): IJHESS AUGUST 2024
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhess.v4i1.1140

Abstract

The Law No.11 of 2020 On Job Creation is a new law that aims to facilitate investment initiated by the government of President joko widodo, in the regulation has expanded the rights to apartment units by foreign citizens. In this context, the issuance of these regulations is important to ensure legal certainty, justice and expediency. This article explores the expansion of property rights to the unit flats associated with the principle of nationality in Law No. 5 of 1960 on agrarian principles. In the expansion of property rights to units of flats by foreign nationals in the job creation law should not ignore what is the purpose of the construction of flats in Indonesia.
Assessing the Impact of Current Ratio, Return On Assets, and Debt To Equity Ratio on Financial Distress of PT Jasa Marga (Persero) Tbk Over the 2013-2022 Listri Herlina; Ilham Nugroho
JAF (Journal of Accounting and Finance) Vol. 8 No. 2 (2024): Journal of Accounting and Finance
Publisher : FEB-Telkom University Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25124/jaf.v8i2.7329

Abstract

This study aims to examine the Financial Distress of PT Jasa Marga (Persero) Tbk through its financial performance. The analysis explores into the challenges associated with infrastructure development, particularly toll roads, wherein the high levels of financing and capital requirements lead to a significant increase in corporate debt. If it is not managed properly, this could potentially result in bankruptcy for the company. Using the Ordinary Least Square (OLS) method to analyze the issue, three internal factor variables were employed: Current Ratio (CR), Return On Assets (ROA), and Debt To Equity Ratio (DER).Based on the research findings, PT Jasa Marga (Persero) Tbk experienced financial distress from the second quarter of 2020 to the second quarter of 2021. Return on Assets (ROA) and Debt to Equity Ratio (DER) emerged as the primary factors influencing financial distress, whereas Current Ratio (CR) had no significant impact on it. With the influence of ROA and DER, PT Jasa Marga (Persero) Tbk faces a high risk concerning its ability to repay debts, attract new investments, or maintain a healthy financial balance. This could lead to a decline in the company's value, difficulties in accessing new sources of funding, or even bankruptcy. PT Jasa Marga (Persero) Tbk must consistently strive to improve its financial performance with careful attention.Keyword: Financial Distress; Current Ratio; Return on Assets; Debt to Equity Ratio; Ordinary Least Square (OLS).