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All Journal Jurnal Sain Veteriner Buletin Peternakan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) INDONESIAN JOURNAL OF PHARMACY ARSHI Veterinary Letters
Christin Marganingsih Santosa
Departemen Patologi Klinik, Fakultas Kedokteran Hewan, Universitas Gadjah Mada, Yogyakarta
Agriculture, Biological Sciences & Forestry Immunology & microbiology Medicine & Pharmacology Neuroscience Veterinary Other

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Journal : INDONESIAN JOURNAL OF PHARMACY

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Phytochemical compounds and the effect of ‘bangunbangun’ leaves (Coleus amboinicus, L.) water extract on phagocytosis activity of neutrophil cell rat (Rattus norvegicus) Christin Marganingsih Santosa; Triana Hertiani
Indonesian Journal of Pharmacy Vol 16 No 3, 2005
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.502 KB) | DOI: 10.14499/indonesianjpharm0iss0pp141-148

Abstract

Traditional medicine has been recognized and widely used in Indonesia for healthy care or alternative medication in certain diseases. However, without scientific evidence, traditional medicine of empirical evidence cannot be used for modern health medication. This research was designed to find out the mains compound despite of Bangun-bangun aqueous extract from Kaliurang district using phytochemistry analysis such as Thin Layer Chromatography method and determine the effect on neutrophil cell activities by observing their phagocytosis. The result showed that the main compounds of Bangun-bangun leaves from Kaliurang district are polyphenol, saponin, flavonol glycoside and essential oil. Administration of the extract with the doses of Bangun-bangun leaves treatment 19,0 g/kg bw/oral/day (group A) and 31,5 g/kg bw/oral/day (group B) increased neutrophil cell phagocytosis up to 50% and 60 %, respectively, compared to those of controls which is 10% during 30 days treatment. Neutrophil cell phagocytosis in group B and C capability increase up to 80% (p
Co-Authors . Kholik Ajeng Tyas Utami Ajeng Tyas Utami Amelia Hana Angkasa, Winoto Claude Mona Airin Dinar Arifianto Ella Romadhona Ella Romadhona Fajar Budi Lestari Imron Rosyadi Munawaroh, Muhammad Pudji Astuti Rini Widayanti Rosyadi, Imron Salasia Isrina Oktavia Siti Sarmin Sarmin Siti Isrina Oktavia Salasia Siti Isrina Oktavia Salasia Triana Hertiani Yayik Nur Hijrati Yayik Nur Hijrati