Article Per Year (5 Year)
p-Index From 2021 - 2026
2.042
P-Index
This Author published in this journals
All Journal Medical Laboratory Technology Journal Jurnal Riset Kefarmasian Indonesia Tropical Health and Medical Research Journal Jurnal Rakat Sehat : Pengabdian Kepada Masyarakat Jurnal Karya Generasi Sehat
Nurlailah Nurlailah
Department Of Medical Laboratory Technology Poltekkes Kemenkes Banjarmasin
Religion Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

Published : 15 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 15 Documents
Search

 1   2 
Correlation Between APTT and Anti-Tuberculosis Therapy Stages at Cempaka Health Center Thuraidah, Anny; Oktiyani, Neni; Nurlailah, Nurlailah; Kustiningsih, Yayuk; Meilinda, Intan
Tropical Health and Medical Research Vol. 7 No. 1 (2025): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v7i1.126

Abstract

Tuberculosis (TB) is an infectious disease that is still a global health problem. TB treatment with anti-tuberculosis drugs can affect the hemostasis system, one of which is through changes in activated partial thromboplastin time (APTT). However, the relationship between APTT values ??and the phase of TB therapy is still not fully understood. This study aims to analyze the relationship between APTT values ??and the phase of TB therapy and patient characteristics, including age and gender. This study used a cross-sectional design with an accidental sampling technique involving 30 pulmonary TB patients undergoing anti-tuberculosis drug therapy at the Cempaka Health Center. APTT examination was performed using an automatic method with a normal value of 25–43 seconds. Statistical analysis used the Pearson correlation test for normally distributed data and the Spearman test for non-normally distributed data. The results showed that 63% of patients had normal APTT values ??(26.0–41.2 seconds; average 32.7 seconds), while 37% of patients experienced prolonged APTT (44.8–49.7 seconds; average 47.6 seconds). There was no significant relationship between APTT values ??and the TB therapy phase (p=0.165), age (p=0.249), and gender (p=0.630). There was no significant relationship between APTT values ??and TB therapy phase, age, and gender. However, these results indicate that some patients experience changes in the hemostasis system during TB therapy. This study suggests that monitoring APTT in TB patients undergoing anti-tuberculosis drug therapy is still needed to anticipate potential coagulation disorders. Further research with a larger sample size and control of nutritional factors and patient inflammation status is recommended to obtain a more comprehensive understanding of the effects of TB therapy on the hemostasis system.
Oral Candida spp. Density as a Blood Glucose Marker in Diabetes Mellitus Patients Insana, Aima; Nurlailah, Nurlailah; Adawiyah, Rabiatul
Tropical Health and Medical Research Vol. 7 No. 2 (2025): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v7i2.133

Abstract

Candida spp. is a commensal fungus in the oral cavity that can become an opportunistic pathogen when there is a decrease in the immune system or metabolic disorders such as diabetes mellitus. Hyperglycemia in people with diabetes increases salivary glucose levels, which can be a nutrient source for Candida, thus triggering increased density, biofilm formation, and antifungal resistance. This study aims to analyse the relationship between blood glucose levels and oral Candida spp. density in patients with diabetes mellitus. The study used a cross-sectional design in 29 Guntung Manggis Banjarbaru Community Health Centre patients. Saliva samples were collected by mouthwash and planted on Hichrome Candida Differential Agar (HCDA) media to calculate colony density. At the same time, blood glucose levels were measured spectrophotometrically using the GOD-PAP method. The results showed abnormal blood glucose levels (?200 mg/dL) were found in 16 respondents (55.2%), and abnormal Candida spp. density (>500 CFU/mL) was also found in 16 respondents (55.2%). The growth of Candida spp. detected in 24 samples (82.8%). The Chi-square test showed a significant association between hyperglycemia and increased oral Candida spp. density (p = 0.017). These findings suggest that hyperglycemia plays a role in increased Candida density in the oral cavity. Hence, monitoring blood glucose levels and oral Candida density is important for preventing fungal infection complications in patients with diabetes mellitus.
Formulation Test of Dracontomelon dao (Blanco) Merr. & Rofe Leaf Extract Powder as an Anti-Diarrheal Escherichia coli Method In Vivo Dwiyanti, Ratih Dewi; Nurlailah, Nurlailah; Thuraidah, Anny
Medical Laboratory Technology Journal Vol. 10 No. 1 (2024): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i1.556

Abstract

Dracontomelon dao (Blanco) Merr. & Rofe is one of the medicinal plants used in the community. This study aims to analyze the effectiveness of  Dracontomelon dao (Blanco) Merr. & Rofe extract powder as an antidiarrheal against Escherichia coli in vivo. Dracontomelon dao (Blanco) Merr. & Rofe leaf comes from Hulu Sungai Utara, South Kalimantan, Indonesia, and is macerated with 96% ethanol—Dracontomelon dao extract powder (Blanco) Merr. & Rofe is made with three parts thick extract, four parts Lactose, and four parts Starch. Experimental rat were conditioned to develop diarrhea and were treated with extract powder with varying doses per kg of body weight, namely 250 mg, 500 mg, and 750 mg. After treatment on day 6, rat recovered from diarrhea in the 750 mg dose treatment group as much as 78%, while the positive control total recovery on day 6 reached 100%. After treatment on day 6, the number of Escherichia coli colonies in rat feces decreased, namely the lowest in the 750mg dose treatment group, 276 colonies/gr. This research concludes that Dracontomelo dao (Blanco) Merr. & Rofe leaf extract powder is effective as an anti-diarrhea against Escherichia coli in experimental rat. Further research is needed on human test subjects to obtain anti-diarrhea drugs with safer and more effective formulations.
EFEKTIVITAS EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA L) SEBAGAI ANTIBAKTERI SALMONELLA TYPHI DAN STAPHYLOCOCCUS AUREUS Fadia, Fadia; Nurlailah, Nurlailah; Helmiah, Tini Elyn; Lutpiatina, Leka
Jurnal Riset Kefarmasian Indonesia Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i3.104

Abstract

Salmonella typhi and Staphylococcus aureus are pathogenic bacteria that cause infectious diseases. Treatment of these diseases can be done by giving antibacterial drugs. One of the plants that can be used as an antibacterial drug is the leaves of Chromolaena odorata L. due to the presence of chemical compounds such as flavonoids, tannins, and saponins that have the potential as antibacterial. This study aims to determine the Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC) ethanol extract of Chromolaena odorata L. leaves on the growth of Salmonella typhi and Staphylococcus aureus. This research is the initial stage of the development of herbal medicines to treat Salmonella typhi and Staphylococcus aureus infections. The study consisted of 5 treatments, namely concentrations of 20%, 40%, 60%, 80%, and 100% ethanol extract of Chromolaena odorata L. leaves with five repetitions. The antibacterial activity test was carried out by MIC and MBC methods. The research material uses leaves from Chromolaena odorata L. in the Sungai Besar area, Banjarbaru, South Kalimantan, Indonesia. The results showed that the average MIC yield of ethanol extract of Chromolaena odorata L. leaves against Salmonella typhi: 20% and Staphylococcus aureus: 20%. While the average yield of MBC values ​​against Salmonella typhi: 40% and Staphylococcus aureus: 40%. Based on the results obtained, it can be concluded that the ethanol extract of Chromolaena odorata L. leaves has an inhibitory effect on the growth of Salmonella typhi and Staphylococcus aureus. Chromolaena odorata L. leaves has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.
EDUKASI DAN PELATIHAN PENGOLAHAN MINUMAN IMUNOMODULATOR PADA PENDERITA TB PARU DI WILAYAH PUSKESMAS CEMPAKA BANJARBARU Dewi Dwiyanti, Ratih; Nurlailah, Nurlailah; Insana, Aima
JURNAL RAKAT SEHAT (JRS) : Pengabdian Kepada Masyarakat Vol 5 No 1 (2026): Jurnal Rakat Sehat
Publisher : UPPM Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jrs.v5i1.90

Abstract

Pulmonary TB is still a disease that is often found in the Cempaka Banjarbaru Community Health Center. Based on data from the Cempaka Health Center for January - December 2022, there are 36 tuberculosis sufferers who are still actively seeking treatment. Treatment of pulmonary TB with anti-tuberculosis drugs (OAT) takes several months so it is prone to causing side effects in sufferers. To minimize the side effects of using OAT while increasing the patient's immune system, it is necessary to consume natural ingredients (moringa, meniran and ginger) which have minimal side effects and act as immunomodulators. The aim of the activity is to increase participants' knowledge about tuberculosis and how it is transmitted as well as how to use herbal plants as immunomodulators to minimize side effects due to the use of OAT. The method used in this activity is filling out a questionnaire sheet (pretest) followed by a presentation of the material. Before the posttest was carried out, the participants were given training on how to process herbal drinks from 3 herbal ingredients, namely Moringa leaves, meniran and ginger (Kemeja) which were made in powder form for 2 hours and continued with filling out a questionnaire sheet (posttest). The results of community service can be seen based on the questionnaire sheet which shows an increase in participants' knowledge about pulmonary TB disease by 10% and behavior in preventing pulmonary TB by 10% and participants were able to make immunomodulatory drinks in the form of powder such as Kemeja (moringa, meniran, ginger). Based on the results of evaluation and monitoring, sufferers stated that their appetite increased after drinking SHIRT tea powder. It is hoped that the increase in appetite can increase the sufferer's immune system so that they can suppress the side effects of the OAT drugs they consume.
Co-Authors Aima Insana Anny Thuraidah Anny Thuraidah Anny Thuraidah, Anny Anton Cahyono, Jujuk Aufa, Muna Dini Aulia Azmi Dinna Rakhmina Erfan Roebiakto Fadia, Fadia Helmiah, Tini Elyn Herlena Fitriani leka lutpiatina, leka Meilinda, Intan Neni Oktiyani Noor Hikmah Damayanti Novina Kusumawardhani Putri, Noorlaily Rabiatul Adawiyah Ratih Dewi Dwiyanti yayuk kustiningsih, yayuk