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All Journal Pharmacon Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Sehat Mandiri Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Borneo Journal Of Pharmascientech Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas Jurnal Ilmiah Farmasi Akademi Farmasi Jember Jurnal Pengabdian Masyarakat JHeS (Journal of Health Studies) Pharmacy Genius SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan Jurnal Farmasi Ikifa
Rani Prabandari
universitas harapan bangsa
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Perbandingan Tingkat Pengetahuan Swamedikasi Nyeri Haid (Dismenore) pada Siswi di SMK Muhammadiyah 3 Purbalingga Indariah Purbasari; Rani Prabandari; Khamdiyah Indah Kuurniasih
Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat Vol 3 No 1 (2023): Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat (SNPPKM 20
Publisher : Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/snppkm.v3i1.1225

Abstract

Dismenore suatu keadaan dimana perempuan mengalami nyeri pada saat menstruasi. Swamedikasi merupakan pengobatan sendiri (self medication) terhadap suatu penyakit atau gejala yang ringan dilakukan dengan obat kimiawi maupun obat tradisional yang dapat dibeli tanpa menggunakan resep dari dokter. Tujuan dari penelitian ini yaitu untuk mengetahui tingkat pengetahuan swamedikasi nyeri haid (dismenore) dan perbandingan antara siswi farmasi dan perbankan syariah SMK Muhammadiyah 3 Purbalingga setelah diberikan intervensi. Metode yang diberikan pada penelitian ini yaitu metode One Group Pretest-Postest dengan total responden berjumlah 96 siswi. Dalam penelitian ini teknik pengambilan sampel yang digunakan adalah random sampling. Hasil penelitian pada tingkat pengetahuan menunjukan bahwa pengetahuan siswi farmasi sebelum diberikan intervensi yaitu baik sebesar (50%) dan sesudah baik (91,7%). Pada siswi perbankan syariah sebelum diberikan intervensi yaitu baik (29,2%) dan sesudah yaitu baik (87,5%). Perbandingan tingkat pengetahuan antara siswi farmasi dan perbankan syariah setelah diberikan intervensi diperoleh p-value 0,015. Sehingga dapat disimpulkan bahwa ada perbedaan yang signifikan antara siswi farmasi dan perbankan setelah diberikan intervensi.
Pengaruh Jenis Pelarut Pada Ekstraksi Bertingkat Biji Jagung Ungu (Zea Mays Var Ceratina Kulesh) Terhadap Aktivitas Antioksidan Gita Rizki Saputri; Dina Febrina; Rani Prabandari
Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat Vol 3 No 1 (2023): Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat (SNPPKM 20
Publisher : Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/snppkm.v3i1.1286

Abstract

Beberapa tahun terakhir, kandungan antioksidan yang tinggi dari antosianin jagung ungu menjadi daya tarik tersendiri untuk digunakan sebagai bahan makanan yang praktis. Efisiensi ekstraksi terutama dipengaruhi oleh pemilihan pelarut. Perbedaan tingkat kepolaran suatu pelarut dapat mempengaruhi nilai rendemen ekstrak, nilai IC50, total fenolik serta total flavonoid. Tujuan dari penelitian ini adalah untuk melihat pelarut mana yang paling berpengaruh terhadap total flavonoid, total fenolik, dan aktivitas antioksidan pada ekstrak biji jagung ungu,serta jenis pelarut yang paling terbaik dalam menghasilkan aktivitas antioksidan pada biji jagung ungu. Data yang diperoleh akan diperiksa normalitas dan homogenitas variansnya, kemudian akan digunakan ANOVA satu arah untuk menganalisis hasilnya. Hasil penelitian menunjukkan bahwa total fenolik, total flavonoid, dan nilai IC50 semuanya dipengaruhi secara signifikan oleh pelarut yang berbeda (P<0,05). Pelarut metanol menghasilkan aktivitas antioksidan yang terbaik berdasarkan IC50 sebesar 33,46 ppm, kadar flavonoid total sebesar 4,97 mg QE/g ekstrak, dan kadar fenolik total sebesar 11,73 mg GAE/g ekstrak. Kata kunci: jagung ungu, ekstraksi bertingkat, antioksidan
Hubungan Tingkat Pengetahuan dengan Swamedikasi Penyakit Neurodermatitis pada Pekerja Proyek di PT. Boyang Purbalingga Anggestia Zakina; Peppy Octaviani; Rani Prabandari
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 1 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i1.437

Abstract

Neurodermatitis or lichen simplex chronicus is defined as a common form of chronic neurodermatitis that presents as dry, patchy areas of skin that are scaly and thick. Self-medication is a person's effort to help himself in the form of self-medicating. This study aims to determine the relationship between knowledge level and self-medication of neurodermatitis in project workers at PT. Boyang Purbalingga. This study used a cross sectional time approach. Research based on SPSS with spearman-rank test of neurodermatitis knowledge level on project workers of PT. Boyang Purbalingga found that most of the respondents had sufficient knowledge level as many as 24 respondents (21.8%) and good knowledge as many as 86 respondents (78.2%). Based on SPSS with spearman-rank test, the level of self-medication of neurodermatitis in project workers of PT. Boyang Purbalingga as many as 7 respondents (6.4%) have sufficient knowledge and 103 respondents (93.6%) have good knowledge. The results of the analysis based on the spearman-rank test obtained a p-value of 0.167 with a significance degree of 5% (0.05). It can be concluded that statistically there is a relationship between the level of knowledge and self-medication of neurodermatitis disease in project workers at PT. Boyang Purbalingga.
UJI AKTIVITAS ANTI INFLAMASI EKSTRAK ETANOL BAWANG MERAH (Allium Cepa L.) VARIETAS BIMA BREBES PADA TIKUS PUTIH JANTAN GALUR WISTAR Abidia Kamil; Adita Silvia; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 5 No 1 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no1p60-64

Abstract

Shallots are one of the leading vegetable commodities in Indonesia. The center for shallot production is Central Java Province, especially in the Brebes Regency area. Shallots (Allium cepa L) can be used as medicine, one of which is as an anti-inflammatory. The purpose of this study was to determine the anti-inflammatory activity and to determine the best dose of ethanolic extract of shallot (Allium cepa L) which has anti-inflammatory activity against male white rats of wistar strain. The method used is the experimental method. Shallot extract (Allium cepa L.) was extracted using 70% ethanol by maceration method. The test animals used were white male rats wistar strain as many as 25 rats weighing 200-250 grams. The test animals were divided into 5 groups, namely the negative control group (Na CMC 0.5%), the positive group (Na Diclofenac), the onion extract dose variation group (25 mg/KgBW, 50 mg/KgBW, and 100 mg/KgBW). . Treatment 1 hour afterthe hind legs of rats was induced by subplantar carrageenin. The measurement of the volume of edema on the soles of the rats' feet was observed once every 1 hour for 6 hours. The results of the study showed that there was antiinflammatory activity at the three doses (25 mg/KgBW, 50 mg/KgBW and 100 mg/KgBW) ethanol extract of shallot (Allium cepa L) Bima Brebes in male white rats of the Wistar strain. The best dose of ethanolic extract of shallot (Allium cepa L) which has anti-inflammatory activity against male white rats of wistar strain is 50 mg/KgBW.
HUBUNGAN KADAR GULA DARAH DENGAN TEKANAN DARAH PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS SOKARAJA 1 Habib Fatah Roniawan; Peppy Octaviani DM; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p74-78

Abstract

Type 2 Diabetes Mellitus is a condition when blood glucose in the body is not controlled due to impaired sensitivity of pancreatic cells to produce the hormone insulin. The World Health Organization (WHO) states that there are 422 million people in the world who suffer from diabetes mellitus, an increase of about 8.5% in the adult population and an estimated 2.2 million deaths. The purpose of this study was to determine the characteristics of patients with type 2 diabetes at the Sokaraja 1 Health Center and to find out how the relationship between blood sugar levels and blood pressure of type 2 diabetes mellitus patients at the Sokaraja 1 Health Center. The method used is observational analysis in perspective with a cross sectional approach. The results of this study using the Pearson correlation test showed that 46 patients were majority aged 51 to 60 (39.1%), male 13 patients (28.3%) female 33 patients (711.7%), long time to diagnose diabetes mellitus greater than 1-4 years (73.9%) and there is a relationship between blood sugar levels and blood pressure with a significance value of 0.375.
FAKTOR RESIKO KEJADIAN DIABETES MELITUS TIPE 2 DI PUSKESMAS PURWOKERTO SELATAN KABUPATEN BANYUMAS Fasikhatul Qomariyah; Peppy Octaviani DM; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p79-84

Abstract

Diabetes Mellitus (DM) type 2 is a metabolic disease characterized by an increase in blood sugar levels caused by a decrease in insulin secretion or insulin function disorders.. The purpose of this study was to determine the risk factors for type 2 diabetes melitus based on age, gender, obesity, physical activity, smoking habits in the South Purwokerto Public Health Center, Banyumas Regency. The method used is quqntitative prospectively using a correlation description design or design with a cross sectional approach. The results of this study using the charactristics of the respondents showed that of the 64 patients the majority of the respondents were aged in the adult category (20-60 years) as many as 34 people (53,1%) and the again in the elderly category (> 60 years) as many as 30 people (46,9%) and none of the respondents wre in the adolescent category (11-19 yeras). Most of the respondents were female as many as 48 people (75,0%) while 26 while the male sex was 16 people (25,0%) 38 respondents (59,6%) were not obese, while 26 respondents were obese (40,6%). Physical activity of category as many as 26 people (40,6%) modrate physical activity as many 20 people (68,8%). Most of the respondents who smoked wre 23 people (35,9%) and there was a relationship between the risk factors of age, gender, obesity, physical activity, smoking habit with type 2 diabetes melitus.
Formulasi Tablet Kunyah Asetosal Dengan Variasi Konsentrasi Gelatin Sebagai Bahan Pengikat Terhadap Uji Fisik Tablet Kinanthi Dwi Utami; Rani Prabandari; Sunarti
Jurnal Farmasi IKIFA Vol. 2 No. 2 (2023): JURNAL FARMASI IKIFA VOL.2 NO.2 OKTOBER TAHUN 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Acetosal, a nonsteroidal anti-inflammatory drug that is included in the category of drugs with a dose of 80 mg. In patients with coronary heart disease and severe hypertension, this drug is used as antiplatelet therapy with the aim of preventing stroke. Acetosals are included in the BCS class II category, so efforts are needed to develop formulations that can increase the speed of dissolution and provide a fast effect. This study aims to determine the variation in gelatin concentration as a binding agent to physical properties and determine the best gelatin concentration that meets the dissolution test of acetosal chewable tablets. The method used to make acetosal chewable tablets is direct felt. Acetosal chewable tablets are made into 3 formulas with variations in the concentration of gelatin binders of 2%, 6%, and 10%. The data obtained is then analyzed with one-way ANOVA. The results showed variations in gelatin concentrations of 2%, 6%, and 10% resulting in good physical properties of acetosal chewable tablets. The gelatin concentration of 2% in formula 1 showed the best results with an average test value of uniformity of weight 220.6 ± 1.42 mg, uniformity of diameter size 0.838 ± 0.01 cm, and thickness 0.436 ± 0.01 cm, hardness 4.3 ±0.15 kg, brittleness 0.49 ± 0.32%, crushing time 31 ± 3.0 seconds and dissolution 95.81%. A significant difference in values was found in the hardness test results (p = 0.001) and the time of destruction (p = 0.000). The best percent dissolution is found in Formula 1 with a dissolution value of 95.81%.
Hubungan antara Polifarmasi dan Kepatuhan Pasien dengan Multimorbiditas di RSUD dr R Goeteng Taroenadibrata Purbalingga Arum Nur Hidayatun; Sunarti Sunarti; Rani Prabandari
Jurnal Sehat Mandiri Vol 19 No 1 (2024): Jurnal Sehat Mandiri, Volume 19, No.1 Juni 2024
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v19i1.1364

Abstract

has a major impact on a person's quality of life. Patients with multimorbidity have the potential to prescribe polypharmacy. This study aims to determine the level of patient adherence and the relationship between polypharmacy and adherence of multimorbid patients at the Internal Medicine Clinic RSUD dr R Goeteng Taroenadibrata Purbalingga. A cross-sectional study using the convenience sampling method was conducted on 342 multimorbid patients receiving polypharmacy prescriptions. Data were collected using demographic questionnaires and the Morisky Medication Adherence Scale (MMAS-8) questionnaire. The average age of the respondents in this study was 57.81 ± 10.596, with an average patient taking 9.8 ± 3.2 drugs per day and having an average diagnosis / number of diseases suffered 3.56 ± 1.06 diagnoses. Patients with low adherence category were 106 people (31%), medium were 125 people (36.5%) and high were 111 people (32.5). Conclusion: There is a significant relationship between polypharmacy (p<0.05) and adherence to taking medication in multimorbid patients (p=0.000), where the more medication the patient gets (polypharmacy), the lower the patient's compliance in taking medication. It is recommended that the hospital carry out evaluations and interventions to improve treatment compliance.
Characterization of Pregelatinized, Pentanol and Acetylated Modified Primary Starch Desy Nawangsari; Rani Prabandari; Dina Febrina
Viva Medika Vol 17 No 1 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i1.1354

Abstract

Tablets are pharmaceutical preparations consisting of active ingredients and excipients. One of the commonly used excipients is starch. (Colocasia esculenta (L). Schott var, Pratama) is a plant that contains a high source of starch. The use of natural starch in tablets has limitations in the form of less fast flow and poor compressibility. The purpose of this study was to modify natural starch by pregelatinization, pentanol and acetylation. This research was conducted using laboratory experimental methods, starting with sorting the starch tubers of (Colocasia esculenta (L). Schott var, Pratama), starch isolation, modification and characterization of the resulting starch. The characterization results showed that the flow rate of natural starch, pregelatinized, pentanol and acetylated sequentially was 1.9 ± 0.19; 2.15 ± 0.37; 1.35 ± 0.15; and 1.95 ± 0.14 g/s with an angle of repose of 20.49 ± 1.99; 17.12 ± 1.99; 22.92 ± 1.18 and 20.06 ± 1.97°, while the compressibility value is 20.23 ± 5.31; 15.47 ± 3.03; 21, 09 ± 2.8 and 19.09 ± 2.05%.
Edukasi Preventif Diabetes Melitus : Perubahan Gaya Hidup Dan Pemanfaatan Terapi Herbal Di Kabupaten Banyumas Rani Prabandari; Theophani Bagas Pradana; Sistia Asfa Fiqrotinnisa; Sevryandi Ega Noer Rachmat Syah; Puput Ma’rifah; Sarjito Hidayat
Jurnal Pengabdian Masyarakat - PIMAS Vol. 5 No. 1 (2026): Februari
Publisher : LPPM Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/pimas.v5i1.2220

Abstract

Diabetes mellitus is a major health challenge globally and in Indonesia, where 2021 data reported 19.4 million cases and 236,711 deaths. In Banyumas Regency, cases reached 22,836 by 2024, notably in East Purwokerto and Sokaraja. This community service initiative aimed to enhance public knowledge of diabetes prevention and management through health promotion. Conducted by pharmacist professional students from Universitas Harapan Bangsa in Kranji and Kalikidang Villages, the program followed a three-stage methodology: preparation involving problem analysis, implementation using PowerPoint and discussions, and evaluation. Educational materials covered diabetes types, risk factors, lifestyle modifications, and the use of herbal drinks as low-side-effect alternative treatments. Results indicated successful implementation and high community enthusiasm. Most participants were unemployed women over 30, identified as a high-risk group due to insufficient physical activity. The evaluation emphasized that using simple language and mastering herbal medicine topics are crucial for meeting practical community needs. In conclusion, health promotion effectively increases public understanding as a vital preventive measure to reduce diabetes prevalence in the Purwokerto. This activity demonstrates that structured educational intervention, when tailored to local demographics and practical interests like herbal remedies, can significantly strengthen community-based efforts in managing chronic metabolic diseases and improving overall public health outcomes
Co-Authors Abidia Kamil Adita Silvia Adita Silvia Fitriana Adriani, Prasanti Anggestia Zakina Anggiani Nuralinda Arum Nur Hidayatun desi nawangsari Desy Nawangsari dina febrina Dwi Novitasari Erni Lovianasari Esti Erdiyati Fasikhatul Qomariyah Fina Rudiyanti Galih Samodra Gita Rizki Saputri Habib Fatah Roniawan Ikhwan Yuda Kusuma Indariah Purbasari Khamdiyah Indah Kuurniasih Kinanthi Dwi Utami Kukuh Yunianto Sumargo Lina Umami Made Suandika Niken Oktaviani Nisa Nur Fadilah Noor Yunida Triana Nur Rifka Zaneta Peppy Octaviani Peppy Octaviani Peppy Octaviani DM Puput Ma’rifah Restu Maulana Riska Fitria Ningsih Riska Norma Sarita Riska Setyaningsih Riza Mustofa Sarjito Hidayat Sevryandi Ega Noer Rachmat Syah Sistia Asfa Fiqrotinnisa Sita Nur Faradila Sita Sunarti Sunarti Sunarti Theophani Bagas Pradana Tjandra Ali Yassin Triana Nur Safitri umi sangadah Windi Nur Fadhilah Yoni Nugrahaning Widhi Yulsela Senaen Yusi Lusiana Amanda Yustiyani Arifah Zahra Amalia Ristiana Zulfa Fadhilah