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Perbandingan Tingkat Pengetahuan Swamedikasi Nyeri Haid (Dismenore) pada Siswi di SMK Muhammadiyah 3 Purbalingga Indariah Purbasari; Rani Prabandari; Khamdiyah Indah Kuurniasih
Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat Vol 3 No 1 (2023): Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat (SNPPKM 20
Publisher : Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/snppkm.v3i1.1225

Abstract

Dismenore suatu keadaan dimana perempuan mengalami nyeri pada saat menstruasi. Swamedikasi merupakan pengobatan sendiri (self medication) terhadap suatu penyakit atau gejala yang ringan dilakukan dengan obat kimiawi maupun obat tradisional yang dapat dibeli tanpa menggunakan resep dari dokter. Tujuan dari penelitian ini yaitu untuk mengetahui tingkat pengetahuan swamedikasi nyeri haid (dismenore) dan perbandingan antara siswi farmasi dan perbankan syariah SMK Muhammadiyah 3 Purbalingga setelah diberikan intervensi. Metode yang diberikan pada penelitian ini yaitu metode One Group Pretest-Postest dengan total responden berjumlah 96 siswi. Dalam penelitian ini teknik pengambilan sampel yang digunakan adalah random sampling. Hasil penelitian pada tingkat pengetahuan menunjukan bahwa pengetahuan siswi farmasi sebelum diberikan intervensi yaitu baik sebesar (50%) dan sesudah baik (91,7%). Pada siswi perbankan syariah sebelum diberikan intervensi yaitu baik (29,2%) dan sesudah yaitu baik (87,5%). Perbandingan tingkat pengetahuan antara siswi farmasi dan perbankan syariah setelah diberikan intervensi diperoleh p-value 0,015. Sehingga dapat disimpulkan bahwa ada perbedaan yang signifikan antara siswi farmasi dan perbankan setelah diberikan intervensi.
Pengaruh Jenis Pelarut Pada Ekstraksi Bertingkat Biji Jagung Ungu (Zea Mays Var Ceratina Kulesh) Terhadap Aktivitas Antioksidan Gita Rizki Saputri; Dina Febrina; Rani Prabandari
Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat Vol 3 No 1 (2023): Prosiding Seminar Nasional Penelitian dan Pengabdian Kepada Masyarakat (SNPPKM 20
Publisher : Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/snppkm.v3i1.1286

Abstract

Beberapa tahun terakhir, kandungan antioksidan yang tinggi dari antosianin jagung ungu menjadi daya tarik tersendiri untuk digunakan sebagai bahan makanan yang praktis. Efisiensi ekstraksi terutama dipengaruhi oleh pemilihan pelarut. Perbedaan tingkat kepolaran suatu pelarut dapat mempengaruhi nilai rendemen ekstrak, nilai IC50, total fenolik serta total flavonoid. Tujuan dari penelitian ini adalah untuk melihat pelarut mana yang paling berpengaruh terhadap total flavonoid, total fenolik, dan aktivitas antioksidan pada ekstrak biji jagung ungu,serta jenis pelarut yang paling terbaik dalam menghasilkan aktivitas antioksidan pada biji jagung ungu. Data yang diperoleh akan diperiksa normalitas dan homogenitas variansnya, kemudian akan digunakan ANOVA satu arah untuk menganalisis hasilnya. Hasil penelitian menunjukkan bahwa total fenolik, total flavonoid, dan nilai IC50 semuanya dipengaruhi secara signifikan oleh pelarut yang berbeda (P<0,05). Pelarut metanol menghasilkan aktivitas antioksidan yang terbaik berdasarkan IC50 sebesar 33,46 ppm, kadar flavonoid total sebesar 4,97 mg QE/g ekstrak, dan kadar fenolik total sebesar 11,73 mg GAE/g ekstrak. Kata kunci: jagung ungu, ekstraksi bertingkat, antioksidan
Hubungan Tingkat Pengetahuan dengan Swamedikasi Penyakit Neurodermatitis pada Pekerja Proyek di PT. Boyang Purbalingga Anggestia Zakina; Peppy Octaviani; Rani Prabandari
BORNEO JOURNAL OF PHARMASCIENTECH Vol 7 No 1 (2023): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v7i1.437

Abstract

Neurodermatitis or lichen simplex chronicus is defined as a common form of chronic neurodermatitis that presents as dry, patchy areas of skin that are scaly and thick. Self-medication is a person's effort to help himself in the form of self-medicating. This study aims to determine the relationship between knowledge level and self-medication of neurodermatitis in project workers at PT. Boyang Purbalingga. This study used a cross sectional time approach. Research based on SPSS with spearman-rank test of neurodermatitis knowledge level on project workers of PT. Boyang Purbalingga found that most of the respondents had sufficient knowledge level as many as 24 respondents (21.8%) and good knowledge as many as 86 respondents (78.2%). Based on SPSS with spearman-rank test, the level of self-medication of neurodermatitis in project workers of PT. Boyang Purbalingga as many as 7 respondents (6.4%) have sufficient knowledge and 103 respondents (93.6%) have good knowledge. The results of the analysis based on the spearman-rank test obtained a p-value of 0.167 with a significance degree of 5% (0.05). It can be concluded that statistically there is a relationship between the level of knowledge and self-medication of neurodermatitis disease in project workers at PT. Boyang Purbalingga.
UJI AKTIVITAS ANTI INFLAMASI EKSTRAK ETANOL BAWANG MERAH (Allium Cepa L.) VARIETAS BIMA BREBES PADA TIKUS PUTIH JANTAN GALUR WISTAR Abidia Kamil; Adita Silvia; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 5 No 1 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no1p60-64

Abstract

Shallots are one of the leading vegetable commodities in Indonesia. The center for shallot production is Central Java Province, especially in the Brebes Regency area. Shallots (Allium cepa L) can be used as medicine, one of which is as an anti-inflammatory. The purpose of this study was to determine the anti-inflammatory activity and to determine the best dose of ethanolic extract of shallot (Allium cepa L) which has anti-inflammatory activity against male white rats of wistar strain. The method used is the experimental method. Shallot extract (Allium cepa L.) was extracted using 70% ethanol by maceration method. The test animals used were white male rats wistar strain as many as 25 rats weighing 200-250 grams. The test animals were divided into 5 groups, namely the negative control group (Na CMC 0.5%), the positive group (Na Diclofenac), the onion extract dose variation group (25 mg/KgBW, 50 mg/KgBW, and 100 mg/KgBW). . Treatment 1 hour afterthe hind legs of rats was induced by subplantar carrageenin. The measurement of the volume of edema on the soles of the rats' feet was observed once every 1 hour for 6 hours. The results of the study showed that there was antiinflammatory activity at the three doses (25 mg/KgBW, 50 mg/KgBW and 100 mg/KgBW) ethanol extract of shallot (Allium cepa L) Bima Brebes in male white rats of the Wistar strain. The best dose of ethanolic extract of shallot (Allium cepa L) which has anti-inflammatory activity against male white rats of wistar strain is 50 mg/KgBW.
HUBUNGAN KADAR GULA DARAH DENGAN TEKANAN DARAH PASIEN DIABETES MELITUS TIPE 2 DI PUSKESMAS SOKARAJA 1 Habib Fatah Roniawan; Peppy Octaviani DM; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p74-78

Abstract

Type 2 Diabetes Mellitus is a condition when blood glucose in the body is not controlled due to impaired sensitivity of pancreatic cells to produce the hormone insulin. The World Health Organization (WHO) states that there are 422 million people in the world who suffer from diabetes mellitus, an increase of about 8.5% in the adult population and an estimated 2.2 million deaths. The purpose of this study was to determine the characteristics of patients with type 2 diabetes at the Sokaraja 1 Health Center and to find out how the relationship between blood sugar levels and blood pressure of type 2 diabetes mellitus patients at the Sokaraja 1 Health Center. The method used is observational analysis in perspective with a cross sectional approach. The results of this study using the Pearson correlation test showed that 46 patients were majority aged 51 to 60 (39.1%), male 13 patients (28.3%) female 33 patients (711.7%), long time to diagnose diabetes mellitus greater than 1-4 years (73.9%) and there is a relationship between blood sugar levels and blood pressure with a significance value of 0.375.
FAKTOR RESIKO KEJADIAN DIABETES MELITUS TIPE 2 DI PUSKESMAS PURWOKERTO SELATAN KABUPATEN BANYUMAS Fasikhatul Qomariyah; Peppy Octaviani DM; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p79-84

Abstract

Diabetes Mellitus (DM) type 2 is a metabolic disease characterized by an increase in blood sugar levels caused by a decrease in insulin secretion or insulin function disorders.. The purpose of this study was to determine the risk factors for type 2 diabetes melitus based on age, gender, obesity, physical activity, smoking habits in the South Purwokerto Public Health Center, Banyumas Regency. The method used is quqntitative prospectively using a correlation description design or design with a cross sectional approach. The results of this study using the charactristics of the respondents showed that of the 64 patients the majority of the respondents were aged in the adult category (20-60 years) as many as 34 people (53,1%) and the again in the elderly category (> 60 years) as many as 30 people (46,9%) and none of the respondents wre in the adolescent category (11-19 yeras). Most of the respondents were female as many as 48 people (75,0%) while 26 while the male sex was 16 people (25,0%) 38 respondents (59,6%) were not obese, while 26 respondents were obese (40,6%). Physical activity of category as many as 26 people (40,6%) modrate physical activity as many 20 people (68,8%). Most of the respondents who smoked wre 23 people (35,9%) and there was a relationship between the risk factors of age, gender, obesity, physical activity, smoking habit with type 2 diabetes melitus.