Article Per Year (5 Year)
p-Index From 2021 - 2026
3.708
P-Index
This Author published in this journals
All Journal Pharmacon Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Ilmiah Farmako Bahari Borneo Journal Of Pharmascientech Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas Jurnal Pengabdian Masyarakat Kolaborasi Jurnal Pengabdian Masyarakat Pharmacy Genius SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT
Galih Samodra
Program Studi Farmasi Program Sarjana, Universitas Harapan Bangsa
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 29 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Pharmacon

 1 
Uji Efek Penurunan Glukosa Darah Dapagliflozin Monoterapi Dan Kombinasi Dengan Glucose Lowering Agent Lainnya Almas Amalul Fasha; Ikhwan Yuda Kusuma; Galih Samodra
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PD IAI JATENG 2021
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.15839

Abstract

The success of DM therapy with antidiabetic drug monotherapy is about 25-50% effectiveness, therefore combination therapy is needed. Inhibitor sodium glucose co-transporter 2 (SGLT-2) is a new anti-diabetic drug intended for personal therapy of patients with type 2 diabetes. SGLT2 inhibitors work by inhibiting glucose reabsorption in the proximal tubule so that glucose will be excreted with urine. SGLT-2 besides being used as monotherapy can also be combined with other DM drugs.  This study aimed to determine the effectiveness of dapagliflozin monotherapy compared to metformin, saxagliptin and glimepiride in alloxan-induced Balb-c strain mice. This research was conducted experimentally on alloxan-induced hyperglycemic mice and the treatment was given for 7 days. The treatment groups were: I. normal, II. alloxan, III. dapagliflozin (D) and the dapagliflozin combination group with: IV. Metformin (DM), V. saxagliptin (DS), VI. Glimepiride (DG), VII. saxagliptin + metformin (DSM). Analysis of the decrease in blood sugar compared between groups on the 7th day after administration. The analysis was carried out using ANOVA test with a 95% confidence level. The results of this study indicate that all treatments with antidiabetic drugs alone or in combination given for 7 days can control blood sugar levels to 120 mg/dL. The combination of dapaglyfozine (DM, DS, DSM) showed a significant difference with groups D and DG (p0.05). The combination of dapagliflozin with Metformin, Saxagliptin and Meformin+Sazagliptin showed a good effectiveness in lowering blood sugar levels compared to other combinations and alone. 
Uji Aktivitas Antioksidan Ekstrak Etanol Kombinasi Daun Kersen (Muntingia calabura L.) dan Daun Kelor (Moringa oleifera L) dengan Metode DPPH (2,2-Diphenyl-1-Picrylhydrayl) Galih Samodra; Nurul Fitri Alfathani; Peppy Octaviani
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 1 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i1.22293

Abstract

Kersen leaves and Moringa leaves are natural sources of antioxidants that can prevent oxidative damage to the body due to free radicals. The purpose of this study was to determine the antioxidant activity of a single form and a combination of cherry leaf extract and Moringa leaf in fighting free radicals. The antioxidant activity test in this study used the DPPH method (2,2-diphenyl-1-picrylhydrazil). The results showed that ethanol extracts of single forms of cherry leaves and Moringa leaves have very strong antioxidant activity with IC50 values of 8.04 ppm and strong 68.40 ppm. The combination with a ratio of 2:1 obtained the lowest IC50 value, which is 6.35 ppm. It can be concluded that the highest antioxidant activity is found in the combination of ethanol extract of cherry leaves and Moringa leaves in a ratio of 2:1, with IC50 smaller than the single form. 
Co-Authors Adita Silvia Febriana Adita Silvia Fitriana Afni Mirlandari Almas Amalul Fasha alviony trista hapsari Alviony Trista Hapsari Anggiani Nuralinda Annima Alfi Fauqina Barlian Kristanto Cecep Darwis Muttaqin Desy Nawangsari Devi Amalila Dewi Rahmawati dina febrina Ega Angelia Narki Elza Puspita Apriliansa Fina Rudiyanti Hadi Jayusman Halimatu Sa'diah Hana Fajrin Ananda Putri Ikhwan Yuda Kusuma Ikhwan Yudha Kusuma indra marselina Indri Wijayanti Khamdiah Kusuma Khofifatul Muamanah Linda Nur Azizah Made Suandika Nur Rahmawati Nurul Fitri Alfathani Pepi Octaviani Peppy Octaviani Purwatiningsih Purwatiningsih Rani Prabandari Reina Melani Riska Fitria Ningsih Siti Setianingsih Umi Hanifatun Nikmah Umi Hanifatun Nikmah Yulsela Senaen Yutia Ihza Komala