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Pengabdian Masyarakat Melalui Kegiatan Penyuluhan Kesehatan Terhadap Tingkat Pengetahuan Tentang Penyakit HIV/Aids di SMAN 1 Baturaden Galih Samodra; Siti Setianingsih; Barlian Kristanto; Reina Melani
Jurnal Pengabdian Masyarakat - PIMAS Vol 2 No 2 (2023): Mei
Publisher : LPPM Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/pimas.v2i2.1059

HIV/AIDS is a health problem in the world, including in Indonesia. he number of HIV/AIDS cases continues to increase from year to year. Adolescents are included in a group that is vulnerable to exposure to HIV/AIDS. As an effort to prevent and transmit HIV / AIDS can be done through health promotion. This activity aims to provide health promotion through outreach activities about HIV/AIDS to students at SMAN 1 Baturraden. The method used is using pretest and posttest. The results of community service activities showed an increase in knowledge about HIV/AIDS as seen from the increase in the score obtained. The conclusion of this activity is that counseling activities are easily accepted and increase knowledge about HIV/AIDS for students of SMAN 1 Baturaden.

Pengabdian Masyarakat Melalui Kegiatan Penyuluhan Kesehatan Terhadap Tingkat Pengetahuan Tentang Penyakit HIV/Aids di SMAN 1 Baturaden Galih Samodra; Siti Setianingsih; Barlian Kristanto; Reina Melani
Jurnal Pengabdian Masyarakat - PIMAS Vol. 2 No. 2 (2023): Mei
Publisher : LPPM Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/pimas.v2i2.1059

HIV/AIDS is a health problem in the world, including in Indonesia. he number of HIV/AIDS cases continues to increase from year to year. Adolescents are included in a group that is vulnerable to exposure to HIV/AIDS. As an effort to prevent and transmit HIV / AIDS can be done through health promotion. This activity aims to provide health promotion through outreach activities about HIV/AIDS to students at SMAN 1 Baturraden. The method used is using pretest and posttest. The results of community service activities showed an increase in knowledge about HIV/AIDS as seen from the increase in the score obtained. The conclusion of this activity is that counseling activities are easily accepted and increase knowledge about HIV/AIDS for students of SMAN 1 Baturaden.

Activity Test of 96% Ethanol Extract of Water Guava Leaf (Syzygium aqueum) on LDL and HDL Values with Propylthiouracil Induction in Rats Siti Setianingsih; Sunarti; Muhammad Maulana
Viva Medika Vol 17 No 2 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i2.1472

One of the plants that can be thought to have antihyperlipidemic potential is water guava leaves (Syzygium aqueum) because they contain chemical compounds, one of which is flavonoids. The aim of this research is to determine the activity of 96% ethanol extract of water guava leaves (EEDJA) as an antihyperlipidemic agent. Male Wistar rats were induced using propylthiouracil (PTU) for 2 weeks (14 days). Hyperlipidemic mice were divided into 5 test groups, CMC-Na group, simvastatin group, EEDJA group (100, 200 and 400) mg/BW. The solution was given to mice routinely once a day for 2 weeks (14 days) orally. The results of the study showed that there were differences before and after administration of EEDJA (100, 200 and 400) mg/BW in LDL and HDL levels with a significance value of 0.000 (<0.005). The conclusion from this study is that EEDJA has potential as an antihyperlipidemic agent in male white Wistar rats

Development of a Pilot Chatbot to Detect Interactions Between Monotherapy and Combination Therapy with Captopril Using a Local (LLM) in Cardiovascular Therapy Ikhwan Yuda Kusuma; Afriza Pujiati; Khamdiyah Indah Kurniasih; Siti Setianingsih; Bizhar Ahmed Tayeb; Nur Arifin Akbar; Muhammad Syaiful Aliim
Journal of Advanced Health Informatics Research Vol. 4 No. 1 (2026)
Publisher : Peneliti Teknologi Teknik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59247/jahir.v4i1.422

Cardiovascular diseases (CVDs), including hypertension and heart failure, remain major contributors to global morbidity and mortality and frequently require long-term polypharmacy. The concurrent use of multiple medications increases the risk of drug–drug interactions (DDIs), which may reduce therapeutic effectiveness, increase toxicity, and contribute to adverse drug reactions. This study aimed to develop and validate a locally deployed large language model (LLM)-based chatbot for detecting drug–drug interactions involving captopril in both monotherapy and combination therapy settings. A development and validation study was conducted using DDI data obtained from DrugBank and Drugs.com. The chatbot was developed using the LLaMA-3 model integrated with LangChain, Ollama, and FastAPI and was evaluated through iterative testing and 5-fold cross-validation. System performance was assessed using accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), while usability was evaluated using the System Usability Scale (SUS) and Single Ease Question (SEQ) questionnaires completed by pharmacists. The chatbot demonstrated progressive performance improvement throughout development and achieved excellent performance during final validation involving 300 drug pairs, with an accuracy of 99.0%, sensitivity of 100.0%, specificity of 98.0%, PPV of 100.0%, and NPV of 92.0%, exceeding all predefined acceptance thresholds. Usability testing indicated only fair to moderate usability, with a mean SUS score of 65.0 and a mean SEQ score of 5.0, suggesting that further refinement of the user interface and workflow may be required. The locally deployed LLM-based chatbot demonstrated satisfactory diagnostic performance and preliminary feasibility for captopril-related DDI screening. Although the system showed promising classification performance, additional usability optimization and evaluation in real-world clinical workflows are needed before broader implementation can be considered as a pharmacist-supportive screening system.

Socialization Of The Risks Of Polypharmacy And Education On Safe Medication Management For Elderly Patients With Degenerative Diseases Siti Setianingsih; Galih Samodra; Mega Kartika Sari; Lukman Hakim; Rian Ardianto; Atina Salamah
SAMBARA: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 3 (2026): September
Publisher : CV Putra Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58540/sambarapkm.v4i3.2073

Peningkatan populasi lansia berdampak pada tingginya penggunaan obat yang berisiko menimbulkan masalah polifarmasi, yang dapat menyebabkan interaksi obat berbahaya dan menurunkan kualitas hidup pasien. Kegiatan pengabdian masyarakat ini bertujuan meningkatkan pemahaman Kader Pemberdayaan Masyarakat (KPM) terkait pengelolaan obat berdasarkan prinsip DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) untuk mencegah risiko polifarmasi pada lansia penderita penyakit degeneratif. Metode yang digunakan adalah Edu-Tech Empowerment Cycle yang meliputi tahapan explore, design, build, implement, dan measure. Kegiatan dilaksanakan di Desa Karangrau dengan melibatkan 20 KPM melalui penyuluhan, diskusi, dan simulasi menggunakan media buku saku dan video tutorial. Evaluasi dilakukan menggunakan kuesioner pre-test dan post-test yang dianalisis secara deskriptif. Hasil kegiatan menunjukkan peningkatan pemahaman peserta pada seluruh indikator, dengan nilai rata-rata meningkat dari 74% pada pre-test menjadi 89% pada post-test. Kesimpulan kegiatan ini menunjukkan bahwa pendekatan edukasi partisipatif berbasis teknologi efektif meningkatkan kapasitas KPM sebagai agen edukasi kesehatan, yang berpotensi mendukung perbaikan kualitas kesehatan masyarakat secara berkelanjutan, khususnya pada lansia penderita penyakit degeneratif.

Pengaruh Leaflet terhadap Motivasi Pengendalian Hipertensi Metode Pretest-Posttest di Puskesmas Sokaraja II dan Sumbang II Risky Devy Lupitasari; Resy Setem; Ruth Gratia Dwi P; Sesilia Tiara Yuvita; Siti Setianingsih
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 5 No. 3 (2026): Juli 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v5i3.9091

Hypertension is one of the non-communicable diseases that remains a major public health problem due to its substantial contribution to morbidity and mortality associated with cardiovascular complications. Effective health education is essential to enhance patients' motivation for hypertension control. This study aimed to analyze the effect of leaflet-based health education on hypertension control motivation among participants of the Chronic Disease Management Program (PROLANIS) at Sokaraja II and Sumbang II Primary Health Centers, Banyumas Regency. This study employed a quantitative approach with a pre-experimental one-group pretest–posttest design. A total of 72 respondents were selected using a random sampling technique. Data were collected using a hypertension control motivation questionnaire administered before (pretest) and after (posttest) the educational intervention using leaflet media. Data were analyzed using univariate analysis to describe respondents' characteristics and motivation levels, while bivariate analysis was performed using the Wilcoxon signed-rank test with a significance level of p<0.05. The results showed an increase in the proportion of respondents with good motivation at Sokaraja II Primary Health Center from 25.00% to 63.89% and at Sumbang II Primary Health Center from 30.56% to 72.22%, accompanied by a decrease in the proportion of respondents with poor motivation. The Wilcoxon signed-rank test demonstrated a statistically significant difference between the pretest and posttest scores (p<0.05). In conclusion, leaflet-based health education was effective in improving hypertension control motivation among PROLANIS participants. Leaflets may serve as an effective health education strategy to support hypertension control in primary healthcare settings.

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