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All Journal Majalah Obstetri dan Ginekologi Health Notions Majalah Kedokteran Neurosains Nommensen Journal of Medicine Indian Journal of Forensic Medicine & Toxicology
Kanti Ismayani
Universitas Ciputra Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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KORELASI ANTARA KADAR CD4 DENGAN SKALA KARNOFSKY PADA PENDERITA AIDS DENGAN TOKSOPLASMOSIS SEREBRI Kanti Ismayani, Isti Suharjanti, Paulus Sugianto
NEURONA Vol 30 No. 1 Desember 2012
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION ABOUT 10 TO 20 OF HIV PATIENTS ULTIMATELY WILL DEVELOP CEREBRAL TOXOPLASMOSIS
The Effectiveness Comparison of Valproic Acid 500 mg and Amitriptyline 15 mg in Reducing the Frequency of Headache Attack in Patients with Tension-Type Headache Elsa Susanti1, Isti Suharjanti1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3143

Abstract

Background: Tension-type headache (TTH) is the most common headache. Continuous analgesic use can develop into headache caused by drug abuse (medication overused headache); thus, the preventive therapy is necessary. Amitriptyline and valproic acid are drugs reported to reduce the frequency of headache in TTH patients. Objective: To analyze the effectiveness of valproic acid 500 mg and amitriptyline 15 mg in reducing the frequency of headache attack in patients with tension-type headache. Methods: The study applied a Double Blind Randomized Clinical Trial involving 50 TTH patients. The subjects were divided into two groups: amitriptyline 15 mg and valproate acid 500 mg. The period of drug administration was 6 weeks. The variables that were compared were the decreasing frequency of headache and the intensity of the pain. Results: There was no significant difference in the decrease of headache frequency (p = 0.730) and pain intensity (p = 0.430) between the amitriptyline group and valproate acid group. However, each drug effectively decreased the frequency of headache and pain intensity in TTH patients (p = 0.000). Conclusion: There was no significant difference between the effectiveness of valproic acid 500 mg and amitriptyline 15 mg in reducing the frequency of headache in patients with TTH.
Association between Intelligence Level and Handicap Degree in Epilepsy Patients Meity Meiliyanny Beslar1, J. Eko Wahono1, Isti Suharjanti1, Paulus Sugianto1, Riani Wisnujono1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3187

Abstract

Background:. Epilepsy correlates with high limitation value, disability and function loss which can give negative impact to patient’s quality of life. This negative impact correlates with either epilectic seizures (motoric, sensory and behavior) or effects of anti-epileptic drugs that can cause cognitive impairment, which in this case is intelligence aspect with handicap in epilepsy patients. We determined correlation between intelligence level and handicap degree in epilepsy patients. Methods: The research was conducted in patients of Neurological Department of Dr. Soetomo General Hospital, Surabaya, Indonesia, who met inclusion and exclusion criteria, consecutively from July 2013-December 2013. Intelligence test was conducted using Standard Progressive Matrices (SPM) test, while test on handicap degree was conducted using Subjective Handicap Epilepsy (SHE) test. Results: There were 40 research subjects (19 females and 21 males) with average age of 30.9±9.6. The average score of SHE was 70.08±16/69, while the average score of SPM was 88.53±10.34. There was a weak positive correlation and statistically significant correlation between SPM and SHE scores (r = 0.345 and p = 0.029). Conclusion: There was a correlation between intelligence level and handicap degree in epilepsy patients.
The Diagnostic Test in Lumbosacral Vertebrae Image towards Magnetic Resonance Imaging in Radicular Low Back Pain Dhimas Hantoko1, Isti Suharjanti1, Sri Andreani Utomo2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.3404

Abstract

Background: Lower back pain is one of the most common consulted cases in neurology and neurosurgery. The approximately 80% of these cases are musculoskeletal disorders. Magnetic resonance imaging (MRI) is still a rare examination in the suburban area and requires a relatively high cost. Moreover, there are contraindications in patients who have cardiac pacemakers and metal objects in the body. The examination of lumbosacral image is easy to conduct. The price is relatively inexpensive and there are no contraindications to perform the test. Objectivity: This study aimed to assess the sensitivity and specificity of the lumbosacral image towards MRI in patients with radicular lower back pain. Method: The study was a clinical, crosssectional study, analytical, and a diagnostic test design. It was performed on all patients with radicular lower back pain in Dr. Soetomo Teaching Hospital Surabaya from April to July 2012. There were 34 subjects who fulfilled the inclusion criteria. Results: The sensitivity of plain images to MRI in detecting radicular lower back pain was 87.5%. This figure indicated that the plain image had a high sensitivity. However, the specificity was only 50.0% which meant that plain image had a low specificity. Conclusion: The lumbosacral image had high sensitivity. However, the specificity was low for the examination of radicular lower back pain.
Pattern of Electroencephalography in Recurrent Febrile Seizure Patient Adinda Chairunnisa; Prastiya Indra Gunawan; Isti Suharjanti
Health Notions Vol 3, No 12 (2019): December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.438 KB) | DOI: 10.33846/hn31203

Abstract

Background: Febrile seizures are seizures that often occur in children, usually of a non-hazardous nature and do not have a prolonged effect. Febrile seizures most often occur in children under five years of age and are reported to occur in 2-5% of the pediatric population. Febrile seizures are categorized as simple, complex and plus febrile seizures. In some patients, EEG is needed to ascertain whether a true febrile seizure occurs. Objective: This study aims to determine the EEG pattern in recurrent febrile seizure patients at the Child Inpatient Installation of Dr. Soetomo Surabaya. Method: This study used a retrospective descriptive method with medical record instruments. Results: This study showed that of 46 recurrent febrile seizures, only 21 patients could see the EEG results. Of the 18 patients with complicated febrile seizures there were 27.78% abnormal and 72.22% normal. One simple febrile seizure patient obtained a normal EEG result. Of the two patients with febrile seizures plus 50% abnormal results and 50% normal results. Conclusions: The EEG pattern in patients with recurring complex febrile seizure obtains the most abnormal result. Keywords: recurrent febrile seizure; electroencephalography; prevalence
The effect of docosahexaenoic acid (DHA) supplementation on total antioxidant capacity (TAC), superoxide dismutase (SOD), and interleukin-6 levels in underweight pregnant women Siahaan, Salmon Charles; Santoso, Budi; Ismayani, Kanti; Yuwono, Natalia; Aris, Mohd Aznan Md
Majalah Obstetri & Ginekologi Vol. 32 No. 3 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I32024.181-188

Abstract

HIGHLIGHTS Underweight pregnant women face an imbalance in energy and protein intake. TAC, SOD, and IL6 with administration of DHA to pregnant women with chronic energy deficiency in the third trimester provide benefits.   ABSTRACT Objective: Underweight pregnant women face oxidative stress and inflammation, increasing their risk of intrauterine growth restriction (IUGR) and preterm birth. This study investigated the effects of DHA supplementation on Total Antioxidant Capacity (TAC), Superoxide Dismutase (SOD), and Interleukin-6 (IL-6) in underweight pregnant women, along with the correlation between DHA and these markers. Materials and Methods: This experimental pre-test/post-test study focused on underweight pregnant women in the Made District, Surabaya, Indonesia. Eligible participants were in their second or third trimester, had a BMI below 18.5, and were taking DHA regularly. Exclusion criteria included early pregnancy (gestational age <14 weeks), BMI above 18.5, irregular DHA intake, and withdrawal from the study. The study was performed from July to December 2023, using non-probability sampling to select participants. Blood samples were collected before and after two months of DHA supplementation. Results: Following the intervention, TAC levels demonstrated a significant increase (p < 0.05). SOD levels also exhibited a significant difference (p <0.05), and IL-6 levels showed a significant change (p < 0.05). A strong and positive correlation (r = 0.718) was observed between the increased TAC and SOD levels. DHA influenced both TAC and IL-6, with a significant relationship between TAC and IL-6 (p < 0.01). Furthermore, elevated SOD levels were associated with a decrease in IL-6 levels (p < 0.01). The correlation coefficient value of 0.718 between changes in SOD and TAC indicated a robust positive correlation. Conclusion: The findings suggest that DHA supplementation in underweight pregnant women positively affects oxidative stress and inflammation markers, improving TAC, SOD, and IL-6 levels.
Spontaneous Bilateral Putamen Hemorrhagic Stroke : A Case Report Suisan, Yohan Christian; Ismayani, Kanti; Adam, Kamila; Hartanto, Edwin; Yujin, Jung
Nommensen Journal of Medicine Vol 9 No 1 (2023): Nommensen Journal of Medicine: Edisi Agustus
Publisher : Universitas HKBP Nommensen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36655/njm.v9i1.904

Abstract

Background: Intracerebral hemorrhage is associated with a high mortality and disability rate, 40% of which happened in non-traumatic ICH patients. Putamen hemorrhage is the most common cause of ICH and strongly associated with hypertension. Until now, bilateral putamen hemorrhagic stroke is still a rare case. Case: Male, 54 years old, admitted to the ER for being unconscious 1 hour earlier. The patient had a history of hypertension but did not receive any treatment. The patient also had a history of schizophrenia and was taking Clozapine, Trifluoperazine, Sertraline, and Dimenhydrinate. Patient was presented with GCS 112, blood pressure 176/104 mmHg, SpO2 98%. Other physical examinations were within normal limits. Head CT scan showed acute ICH in the right putamen (vol ±7.8cc) and left putamen (vol ±20.7cc). Conservative management was given, but there was no neurological improvement. On day 14, complications of pneumonia occurred and the patient later died due to cardiopulmonary arrest. Discussion: Spontaneous bilateral putamen hemorrhagic stroke is a rare type of ICH and loss of consciousness is the main manifestation of the condition. Hypertension is the most common etiology of bleeding, but the exact mechanism is still unknown. Mortality in patients with spontaneous bilateral putamen bleeding is very high and to date, conservative therapy is the main treatment for patients with these conditions. Conclusion: Spontaneous bilateral putamen hemorrhagic stroke is a rare case with a high mortality rate and so far, the main treatment for this case is conservative management. Keywords: stroke, ICH, bilateral, putamen
Co-Authors Adam, Kamila Adinda Chairunnisa Aris, Mohd Aznan Md Dwi Budi Santoso Edwin Hartanto Natalia Yuwono Prastiya Indra Gunawan Siahaan, Salmon Charles Yohan Christian Suisan Yujin, Jung