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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL ILMIAH KESEHATAN SANDI HUSADA JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi Jurnal Ilmiah Kesehatan Sandi Husada
Chandra Susanto
Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Materials Science & Nanotechnology Nursing Physics Public Health

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PENGARUH STROBILANTHES CRISPUS BI TERHADAP KHM DAN KBM PADA BAKTERI AGGREGATIBACTER ACTINOMYECETEMCOMITANS DAN FUSOBACTERIUM NUCLEATUM SECARA IN-VITRO Fenny Wantenia; Chandra Susanto; M Suksestio W
Jurnal Ilmiah dan Teknologi Kedokteran Gigi Vol 16, No 1 (2020)
Publisher : Fakultas Kedokteran Gigi Universitas Prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/jitekgi.v16i1.1012

Abstract

Latar belakang : penyakit periodontitis adalah penyakit yang dapat merusak jaringan ligamen dan tulang alveolar. Penyebab periodontitis adalah bakteri gram negatif, yaitu bakteri Aggregatibacter actinomycetemcomitans dan Fusobacterium nucleatum. Tujuan : untuk mengetahui pengaruh bakteri Aggregatibacter actinomycetemcomitans dan Fusobacterium nucleatum terhadap pengaruh ekstrak daun Strobilanthes crispus BI. Metode : jenis penelitian ini adalah eksperimental laboratorik, sebanyak 5 sampel dalam satu jenis bakteri yang diuji. Sampel di lakukan dengan di larutkan di dalam etanol kemudian dilakukan dengan percobaan 5 replikasi dalam berbagai konsentrasi dan di inkubasikan di dalam tabung reaksi selama 24 jam di dalam inkubator. Hasil : penelitian ini  dilakukan dengan pengujian DMRT (Ducan Multiple Range Test) pada 5% yang menunjukkan pengaruh Aggregatibacter actinomycetemcomitans dan Fusobacterium nucleatum. Dari hasil penelitian ini, ekstrak daun keji beling 100% dapat menujukkan nilai absorbansi terendah pada kadar hambat minimum dan kadar bunuh minimum terhadap bakteri Aggregatibacter actinomycetemcomitans dan Fusobacterium nucleatum secara berturut-turut 0.1540 dan 0.4072, yang menunjukkan bahwa larutan tersebut menjadi lebih jernih. Sedangkan pada perlakuan ekstrak daun keji beling 20% dan 40% menujukkan nilai absorbansi 1.3192 dan 1.2120 yang memiliki nilai yang lebih rendah dari kontrol. Kesimpulan : pengaruh ekstrak daun Strobilanthes crispus BI memberikan efek mampu menghambat pertumbuhan pada Aggregatibacter actinomycetemcomitans dan Fusobacterium nucleatum.
Pengaruh Perendaman Air Perasan Jeruk Lemon dan Asam Cikala Terhadap Kekasaran Permukaan Resin Komposit Nanofiller Rut Viodetta Sirait; Chandra Susanto; Dian Soraya Tanjung
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 1 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i1.587

Abstract

Introduction; The smooth surface of the nanofiller composite resin can become rough with the consumption of acidic foods/drinks. Objectives; know the difference of the effect of immersion of lemon juice and cikala acid juice on the roughness of the nanofiller composite resin. Method; laboratory experimental research with nanofiller composite resin samples. Statistical test using ANOVA test. Results; showed that there was a significant difference (p <0.05) between the roughness of the nanofiller composite resin soaked in cikala acid juice and the control group but the results showed no significant difference (p> 0.05) between the roughness of the nanofiller composite resin immersed in water. lemon juice with the control group. Conclusion; that there is a significant difference between the effect of soaking water with cikala acid juice and lemon juice on the surface roughness of the nanofiller composite resin
Efektivitas Antibakteri Hidrogel Lidah Buaya pada Treponema denticola dan Tannerela forsythia Bakteri: In Vitro Chandra Susanto; Steven Wijaya; Ramayani Efendi; Ridha Mahrani
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 1 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i1.601

Abstract

Introduction; Treponema denticola and Tannerela forsythia bacteria as the main cause of periodontal disease. The aim was to determine the effectiveness of hydrogel aloe vera with antibacterial concentrations of 2.5%, 5%, 10%, and 20% against Treponema denticola and Tannerela forsythia: in vitro bacteria. Method; is a laboratory experimental study with a post-test-only control group in vitro design. The research sample was Treponema denticola and Tannerela Forsythia. Data collection by measuring the diameter of the drag zone using a slide caliper. Data were analyzed using one-way ANOVA and LSD. Results; showed that there were differences in the hydrogel diameter of the inhibitor concentration of aloe vera 2.5%, 5%, 10%, 20%, and positive control in Treponema denticola and Tannerela forsythia bacteria. Conclusion; that there is antibacterial effectiveness of hydrogel aloe vera concentrations of 2.5%, 5%, 10%, and 20% in Treponema denticola and Tannerela forsythia bacteria.
Pengaruh Perendaman Air Perasan Jeruk Lemon dan Asam Cikala Terhadap Kekasaran Permukaan Resin Komposit Nanofiller Rut Viodetta Sirait; Chandra Susanto; Dian Soraya Tanjung
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 1 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i1.587

Abstract

Introduction; The smooth surface of the nanofiller composite resin can become rough with the consumption of acidic foods/drinks. Objectives; know the difference of the effect of immersion of lemon juice and cikala acid juice on the roughness of the nanofiller composite resin. Method; laboratory experimental research with nanofiller composite resin samples. Statistical test using ANOVA test. Results; showed that there was a significant difference (p <0.05) between the roughness of the nanofiller composite resin soaked in cikala acid juice and the control group but the results showed no significant difference (p> 0.05) between the roughness of the nanofiller composite resin immersed in water. lemon juice with the control group. Conclusion; that there is a significant difference between the effect of soaking water with cikala acid juice and lemon juice on the surface roughness of the nanofiller composite resin
Efektivitas Antibakteri Hidrogel Lidah Buaya pada Treponema denticola dan Tannerela forsythia Bakteri: In Vitro Chandra Susanto; Steven Wijaya; Ramayani Efendi; Ridha Mahrani
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 1 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i1.601

Abstract

Introduction; Treponema denticola and Tannerela forsythia bacteria as the main cause of periodontal disease. The aim was to determine the effectiveness of hydrogel aloe vera with antibacterial concentrations of 2.5%, 5%, 10%, and 20% against Treponema denticola and Tannerela forsythia: in vitro bacteria. Method; is a laboratory experimental study with a post-test-only control group in vitro design. The research sample was Treponema denticola and Tannerela Forsythia. Data collection by measuring the diameter of the drag zone using a slide caliper. Data were analyzed using one-way ANOVA and LSD. Results; showed that there were differences in the hydrogel diameter of the inhibitor concentration of aloe vera 2.5%, 5%, 10%, 20%, and positive control in Treponema denticola and Tannerela forsythia bacteria. Conclusion; that there is antibacterial effectiveness of hydrogel aloe vera concentrations of 2.5%, 5%, 10%, and 20% in Treponema denticola and Tannerela forsythia bacteria.
Effectiveness of Acemannan Hydrogel Administration at Concentrations of 25%, 50%, 75% Against Decrease in the Number of Macrophages in Periodontitis Rats with Diabetes Mellitus Chandra Susanto; Susanna Halim; Gusbakti Rusip; Nada Aurelia
Jurnal Penelitian Pendidikan IPA Vol 10 No 4 (2024): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i4.7077

Abstract

Acemannan activity as a natural polysaccharide from Aloevera has good biodegradability and biocompatibility and has an effect on cell tissue repair. The study's objective was to ascertain whether giving Hydrogel Acemannan at concentrations of 25%, 50%, and 75% would be beneficial in lowering the quantity of macrophages in diabetic periodontitis mice . 48 white Wistar rats were used as research samples, and they were split into four groups at two different observation intervals (days 3 and 7).One-way ANOVA and posthoc LSD statistical tests were used to assess the data. The number of macrophages in each group decreased on day 7 to 3.50 ± 0.354; 2.79±0.431; 1.54 ± 0.292; 0.54 ± 0.292. The results of the one-way ANOVAX test (p≤0.05) showed that the Hydrogel Acemannan concentrations of 25%, 50%, and 75% were effective in reducing the number of macrophages in periodontitis mice with diabetes mellitus. The results of the LSD posthoc test showed that Hydrogel Acemannan concentrations of 25%, 50%, and 75% were substantially more effective than the positive control in reducing the number of macrophages in periodontal mice with diabetes mellitus (p≤0.05).
Co-Authors Dian Soraya Tanjung Fenny Wantenia Gusbakti Rusip M Suksestio W Nada Aurelia Ramayani Efendi Ridha Mahrani Rut Viodetta Sirait Steven Wijaya Susanna Halim