Article Per Year (5 Year)
p-Index From 2020 - 2025
2.195
P-Index
This Author published in this journals
All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences METAMORFOSA Journal of Biological Sciences Jurnal Biologi Udayana Jurnal Ilmu Dasar BERKALA SAINSTEK Biosfer: Jurnal Tadris Biologi UNEJ e-Proceeding BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) BIOEDUKASI BIOEDUSCIENCE Biota
Mahriani Mahriani
Biology Department, Faculty Of Mathematics And Natural Sciences, Universitas Jember, East Java, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Control & Systems Engineering Education Environmental Science Immunology & microbiology Library & Information Science Mathematics Medicine & Pharmacology Physics Social Sciences Other

Published : 19 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : UNEJ e-Proceeding

 1 
THE EFFECT OF SOY TEMPEH FLOUR EXTRACT ON VAGINA HISTOLOGICAL STRUCTURE OF SWISS WEBSTER OVARIECTOMIZED MICE (MUS MUSCULUS) Mahriani Mahriani; Eva Tyas Utami; Dita Ayu Faradila
UNEJ e-Proceeding 2016: Proceeding The 1st International Basic Science Conference
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Estrogen deficiency can changes the reproductive system especially in menopausal women, such as a decreasing of smooth muscle contraction, a thinning of vaginal structure, epithelial atrophy and a collagen decreasing. The disorders can be overcome by phytoestrogens treatment. Tempeh is a fermented soy product contains isoflavones that has estrogen-like structure with 17β-estradiol so that it can be able to bind estrogen receptors. Ovariectomized animal as animal test model has estrogen deficiency. Therefore, the purpose of this study to determine the effect of tempeh soy flour extract on vagina histological structure of Swiss Webster ovariectomized mice. The method used animals tested by treating 45 female Swiss Webster mice that were divided into five groups: negative control group (normal mice had not ovariectomized was not given tempeh flour extract), positive control (ovariectomized mice was not given tempeh flour extract), the treatment group (ovariectomized mice and was given tempeh flour extract D1 (0.21 g/ml / day), D2 (0.42 g/ml/day), and D3 (0,63 g/ml/day). Soy tempeh flour extract was given for 10, 20, and 30 days by gavage. The histological parameter were observed include tunica mucosa epithelium and tunica muscularis thickness of vagina. The result showed that tempeh flour extract increase epithelium thickness and tunica muscularis of the vagina ovariectomized mice. Treatment by taking longer time and giving higher dosage of tempeh flour extract could increase the ephitelium thickness of tunica mucosa and tunica muscularis vagina. The treatment of 0.63 g/ml/day dosage during 30 days showed the highest thickness average values of epithelium and tunica muscularis. The ephitelium thickness was 33.90 μm and the tunica muscularis dense was 90.20 μm.
THE EFFECT OF SOY TEMPEH FLOUR EXTRACT TO UTERINE HISTOLOGY OF OVARIECTOMIZED MICE Eva Tyas Utami; Mahriani Mahriani; Nidaul Hikmah
UNEJ e-Proceeding 2016: Proceeding The 1st International Basic Science Conference
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Uterine is one of organs that affected by estrogen hormone. This hormone can influence to increase uterus cells proliferation. Decreasing ovum production cause decreasing of estrogen level. This situation is faced of menopause that affect on uterine development. Phytoestrogens can bind to estrogen receptor and produce estrogenic affects like endogeneous estrogen. Tempeh is known as soybean fermented and consists of high level of isoflavon as phytoestrogens. Phytoestrogens have structure like mammalian estrogen 17β-estradiol. The aim of this study was to know effects of tempeh soy fluor extracts on mice uterine strain swiss webster ovariectomized.. Dosages that used on this study are 0.21g/mL, 0.42 g/mL and 0.63g/mL. The dosages are treated by gavage during 10 and 20 days after ovariectomy.The result showed that tempeh soy fluor extracts can increase the average of uterine mass, endometrial and myometrium thickness during treatment on 10 and 20 days. The 0,63g/mL dosage increase the highest of uterine mass (0.043g), endometrium thickness (389.46μm) and myometrium thickness ( 71.30μm.).
Co-Authors Aminuyati ariza budi tunjung-sari ariza budi tunjung-sari, ariza budi Bella Dwi Arifianti Dewi, Efie Fadjrijah Eka Dita Ayu Faradila Dwi Erlinda Eva Tyas Utami Gusti Agung Perias Tiningrum Gusti Agung Perias Tiningrum, Gusti Agung Perias Hidayat Teguh Wiyono Indah Salsabila Kurnia Isna Kurotul Akyun Kartika Senjarini Kurnia, Indah Salsabila Masrurotul Hasanah Misnawi Jati Misnawi Jati Nana Zaimatul Husna Nidaul Hikmah Primasari, Nindita Fitria Resa Miftahatu Yuniar Rike Oktarianti Rosita Dewi Siti Agustina Wulandari Susantin Fajariyah Teguh Wahyudi Teguh Wahyudi Yenny Febriana Ramadhan Abdi