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All Journal Pharmascience Jurnal Pengabdian Al-Ikhlas Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal AFAMEDIS Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Rakhmadhan Niah
Akademi Farmasi ISFI Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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UJI DAYA HAMBAT EKSTRAK KULIT BUAH PISANG KEPOK (Musa paradisiaca forma typica) TERHADAP Shigella dysenteriae DAN Salmonella typhi Novia Ariani; Rakhmadhan Niah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.801 KB) | DOI: 10.36387/jiis.v3i2.184

Abstract

Masalah global yang sedang dihadapi salah satunya adalah efek samping penggunaan antibiotik baik pada negara berkembang maupun negara maju sehingga perlu dilakukan beberapa tindakan untuk mengatasi permasalahan global yang sedang terjadi. Salah satu upaya yang sedang dilakukan adalah mencari alternatif pengobatan dengan senyawa aktif yang berasal dari alam. Salah satu tanaman yang memiliki khasiat sebagai antibakteri adalah kulit pisang kepok dengan nama ilmiah Musa paradisiaca. Tujuan penelitian ini adalah untuk mengetahui ada tidaknya aktivitas zona hambat dan klasifikasi daya hambat dari ekstrak kulit pisang kepok terhadap bakteri Shigella dysenteriae dan Salmonella typhi.Jenis penelitian ini adalah penelitian eksperimental dengan metode sumuran yang dilakukan di laboratorium Mikrobiologi Akademi Farmasi ISFI Banjarmasin. Sampel yang digunakan adalah pisang kepok mentah yang berasal dari Desa Jaro yang memenuhi kriteria. Metode ekstraksi yang digunakan adalah maserasi dengan pelarut etanol 96%. Penelitian ini terbagi menjadi 2 kelompok utama yaitu kelompok ekstrak dan kontrol negatif. Zona hambat yang terbentuk diukur dengan menggunakan jangka sorong.Hasil penelitian menunjukkan bahwa ekstrak kulit buah pisang kepok dengan konsentrasi 10% memiliki daya hambat terhadap bakteri Shigella dysenteriae dan Salmonella typhi dengan klasifikasi daya hambat kuat. 
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% RIMPANG LENGKUAS MERAH (Alpinia purpurata (Vieill.) K.Schum) TERHADAP BAKTERI Staphylococcus aureus Rakhmadhan Niah; Saftia Aryzki; Anna Khumaira Sari; Shela Puzi Dina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.045 KB) | DOI: 10.36387/jiis.v4i1.290

Abstract

Alpinia purpurata (Vieill.) K.Schum contains flavonoids, tannins, saponins, and terpenoids which have bacterial inhibitory power. This study aims to determine the antibacterial activity test of ethanol extract 96% Alpinia purpurata (Vieill.) K.Schum on the growth inhibition power of Staphylococcus aureus. This research is an experimental research. Antibacterial activity test of extract ethanol 96% Alpinia purpurata (Vieill.) K.Schum using Cup Plate Technique with concentrations of 40%, 30%, 20%, 10% and 5%, Clindamycin concentration 50μg/ml as control (+) and 96% ethanol as control (-) in each treatment replication 4 times. The results diameter of the inhibitory zone formed was then analyzed by Statistical Producy Service Solution (SPSS) version 17. The results showed that extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum had inhibitory activity on the growth of Staphylococcus aureus. The average diameter of the extract ethanol 96% inhibition zone of Alpinia purpurata (Vieill.) K.Schum with a concentration of 40%, 30%, 20%, 10% and 5%, positive control (clindamycin), and negative control (96% ethanol) respectively on Staphylococcus aureus bacteria is 28.06 mm; 25.17 mm; 23.15 mm; 20.38 mm; 18.34 mm; 30.13 mm; 0 mm. There are significant differences in diameter of inhibitory zones between concentrations of extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum on the growth of Staphylococcus aureus bacteria with significance values 0,000.
POTENSI EKSTRAK KULIT LIMAU BANJAR (Citrus reticulata) DENGAN METODE DPPH SEBAGAI ANTIOKSIDAN Bela Ghonim Nashucha; Rakhmadhan Niah; Lutfi Anggraini; Winola Exliscia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.313 KB) | DOI: 10.36387/jiis.v4i2.323

Abstract

Free radicals are a factor that causes various degenerative diseases to occur. Degenerative diseases have become the biggest cause of death in Indonesia, such as cancer, diabetes, heart disease and premature aging. The body needs an important substance to help protect against attacks by free radicals that work by reducing the negative effects of these compounds, namely antioxidants. Natural antioxidants can be obtained through the consumption of herbal plants that contain secondary metabolites of antioxidants, such as banjar orange peel (Citrus reticulata). The aim of this study was to determine the antioxidant activity of banjar orange peel extract which was expressed by inhibitors Consentration 50 (IC50). The banjar orange peel was extracted by maceration method using aquadest solvent and antioxidant activity was tested using the DPPH (1,1-diphenyl-2-picrylhydrazly) method by UV-Vis spectrophotometry at a wavelength of 517 nm. The results showed that the banjar orange peel contained antioxidants which were 10 ppm (29,814%), 20 ppm (35,182%), 30 ppm (43,482%), 40 ppm (50,022%), 50 ppm (58,682%) with IC50 values ​​of 39,041 ppm which is included in the range of very strong antioxidant activity. The conclusion of the study is that the banjar orange peel extract has the potential to be developed as a source of natural antioxidants for humans.
PROFIL SENYAWA DAN AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN SEPAT (Mitragynaspeciosa) DAN DAUN DADANGKAK (Hydrolea spinosa L.) Rakhmadhan Niah; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.91 KB) | DOI: 10.36387/jiis.v4i2.352

Abstract

Sepat folium (Mitragynaspeciosa) and dadangkak folium (Hydrolea spinosa L.) are plants in South Kalimantan. These plants are often used traditionally to reduce blood sugar and antibacterial levels. The effectiveness is suspected because there is strong antioxidant activity in flavonoid compounds. Flavonoid compounds work through the mechanism of capturing free radicals, reducing oxidative stress. The purpose of this study was to determine the profile of flavonoid compounds of sepat folium and dadangkak folium by test the antioxidant activity with DPPH (1,1-diphenyl-2picrylhydrazyl) method. Extract of sepat folium and dadangkak folium were made by the maceration method using methanol as a solvent. Profiles of flavonoid compounds were obtained quantitatively by the standard solution of quercetin. The extract obtained was tested for antioxidant activity by the DPPH (1,1-diphenyl-2picrylhydrazyl) method. The results showed that the total flavonoid value in methanol solvent was the extract of dadakak folium is 51.19 mg QE / g extract and extract of sepat folium is 43.25 mg QE / g extract. Very strong antioxidant activity (<50 μg / mL) was found in methanol extracts of sepat folium with a value of 34.70 μg / mL and methanol extracts of dadangkak folium with a value of 38.41 μg / mL.
KARAKTERISASI SIMPLISIA DAN EKSTRAK KULIT BATANG SEKILANG (Embelia borneensis Scheff.) Risa Supriningrum; Reksi Sundu; Triswanto Sentat; Rakhmadhan Niah; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.634 KB) | DOI: 10.36387/jiis.v6i2.677

Abstract

The Sekilang plant (Embelia borneensis Scheff.) Is one of the plants used by the Dayak community for fishing, leech repellent and as an ingredient for hair care. Empirical use of plants can be developed into products based on natural ingredients. This must be supported by research data. As a first step, the simplicia and ethanol extract of the stem bark were characterized. The research objective was to determine the specific and non-specific characteristics of the simplicia and the extracts of the bark of the sekilang. The research stage includes plant determination, collection of raw materials, manufacture of simplicia, extract preparation, organoleptic, microscopic testing, phytochemical screening, determination of water soluble extract content, determination of ethanol soluble extract content, determination of water content and determination of ash content. Microscopy test results of sekilang stem bark showed the presence of fiber fragments, stone cells, and oxalate crystals. The average water soluble content for simplicia and sekilang bark extract was 7.5% and 80%. The average ethanol soluble content for simplicia and extract was 6% and 30%. The average moisture content for the simplicia and extract was 9.5% and 12%. The mean total ash content for simplicia and extract was 5% and 8.5%. The mean acid insoluble ash content for simplicia and extract was 1% and 0.5%.
UJI AKTIVITAS ANTOKSIDAN EKSTRAK BUAH LIMPASU (Baccaurea lanceolata) Rakhmadhan Niah; Dwi Rizki Febrianti
AFAMEDIS Vol. 1 No. 1 (2020): Jurnal Farmasi Indonesia AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (152.797 KB)

Abstract

Buah limpasu (Baccaurea lanceolata) merupakan tumbuhan daerah Kalimantan Selatan. Tumbuhan tersebut sering dimanfaatkan secara tradisional untuk mengurangi kadar gula dalam darah dan antibakteri. Efektivitas tersebut diduga karena terdapat aktivitas antioksidan kuat pada senyawa golongan flavonoid. Tujuan penelitian ini adalah mengetahui aktivitas antioksdian ekstrak etanol 96% buah limpasu. Ekstrak Buah limpasu dibuat dengan metode maserasi menggunakan pelarut etanol 96%. Uji Aktivitas antioksidan dilakukan dengan menggunakan metode DPPH (1,1-diphenyl-2picrylhydrazyl). Ekstrak buah limpasu dengan menggunakan metode maserasi memiliki daya antioksidan yang mana tergolong antioksidan lemah dengan nilai IC50 404,41 ppm.
PROGRAM BINA DESA DALAM PEMBERDAYAAN MASYARAKAT UNTUK PEMANFAATAN TANAMAN OBAT KELUARGA DI DESA TATAH LAYAP KABUPATEN BANJAR Mochammad Maulidie Alfiannor Saputera; Anna Khumaira Sari; Dwi Rizki Febrianti; Rakhmadhan Niah; Eka Kumalasari
JURNAL PENGABDIAN AL-IKHLAS UNIVERSITAS ISLAM KALIMANTAN MUHAMMAD ARSYAD AL BANJARY Vol 6, No 1 (2020): AL-IKHLAS JURNAL PENGABDIAN
Publisher : Universitas Islam kalimantan MAB

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.447 KB) | DOI: 10.31602/jpaiuniska.v6i1.3364

Abstract

Program bina desa di Desa tatah layap telah dilaksanakan sejak tahun 2018. Pertama kali program bina desa ini yaitu melakukan penanaman tanaman obat keluarga (TOGA). Program ini bertujuan untuk meningkatkan sikap peduli, dan kondisi keberadaan masyarakat terhadap perekonomian dalam meningkatkan taraf hidup dan pemenuhan hasil produk dari TOGA itu sendiri. Program kali ini yaitu memanfaatkan TOGA tersebut untuk diolah menjadi sebuah produk kesehatan yaitu pengolahan produk masker wajah dan lulur. Masyarakat yang dilibatkan kali ini yaitu para pemuda yang berasal dari Desa Tatah Layap. Jumlah peserta pada kegiatan ini sebanyak 31 orang. Metode yang digunakan dalam pengabdian masyarakat ini yaitu perpaduan antara pemberdayaan masyarakat dan pendampingan dengan melibatkan mahasiswa pada peserta program bina desa tahun 2019. Langkah awal dengan memanfaatkan TOGA yang telah ditanam kemudian diberikan pelatihan dalam pemanfaatan TOGA. Langkah berikutnya yaitu pembuatan masker wajah dan lulur. Hasil menunjukan bahwa para pemuda dapat membuat sejumlah masker wajah dan lulur.
POTENSI EKSTRAK DAUN TANAMAN KARAMUNTING (Melastoma malabathricum L.) DI DAERAH KALIMANTAN SEBAGAI ANTIBAKTERI Staphylococcus aureus Rakhmadhan Niah; Riki Nirwan Baharsyah
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.138

Abstract

The year 2008 recorded the death toll reached 16,769 soul due to infection. Infection is one of the diseases caused by bacteria or parasites. Staphylococcus aureus is one of the bacteria causes infection of the skin that is often the case in Indonesia. Staphylococcus aureus bacterial infection can be treated naturally, one of the plants that can be utilized is plant karamunting. Plant leaf karamunting (Melastoma malabathricum l.) contain flavonoids and alkaloids that have activity as antibacterial. The purpose of this research is to know the power of drag karamunting folium of extract against the growth of Staphylococcus aureus. In vitro studies were conducted with diffusion agar method. The extraction of leaf maceration method done with karamunting solvent ethanol 96%. Concentration of karamunting folium of extract used are: 25%, 50%, 75%, and 100%. Microbiology research results indicate that karamunting folium of extract have drag against the growth of bacteria Staphylococcus aureus with extract concentration 50% yield of 5.34 mm; the concentration of extract 75% of 9.40 mm; the concentration of extract 100% of 12.43 mm.
Co-Authors Anna Khumaira Sari Ayuchecaria, Noverda Bela Ghonim Nashucha Eka Kumalasari Eka Kumalasari Febrianti, Dwi Rizki Helda Helda Lutfi Anggraini Mochammad Maulidie Alfiannor Saputera Novia Ariani Novia Ariani Rahmatul Jannah Reksi Sundu Riki Nirwan Baharsyah Riki Nirwan Baharsyah Risa Supriningrum Saftia Aryzki Shela Puzi Dina Siti Latifah Susanto, Yugo Triswanto Sentat Winola Exliscia