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PENETAPAN KADAR FENOLIK TOTAL EKSTRAK ETANOL 70% DAN FRAKSI ETIL ASETAT DAUN BAWANG DAYAK (Eleutherine palmifolia (L.) Merr) DENGAN METODE SPEKTROFOMETRI UV-VIS Eka Kumalasari; Nazulla Mudjib Nararia; Siska Musiam
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.665

Dayak onion (Eleutherine palmifolia (L.) Merr). Is used by the people in Central Kalimantan as a traditional treatment by utilizing onion dayak tubers while the leaves are rarely used, the part of dayak onion leaves also have the potential to naturally be useful as traditional medicine because they contain compounds phenol. Phenol compounds are useful as antioxidants, anti-inflammatory, hemostatic and antitumor. The purpose of this study was to determine the content of phenolic chemical compounds in ethyl acetate fraction and 70% ethanol extract of dayak onion leaves and find out the total phenolic content contained. The sample in this study is Dayak onion leaves from Palangkaraya, Central Kalimantan. Extraction of onion dayak leaves using maceration method. Fraction extract was made by liquid-liquid extraction method with ethyl acetate solvent. The level determination method used was Uv-Vis Spectrophotometry with Folin ciocalteau reagent. The results of this study indicate that from 70% ethanol extract and dayak onion leaves ethyl acetate fraction is containing phenolic compounds. Phenolic levels in this study obtained total levels of dayak onion leaves ethyl acetate fraction was 10.61% ± 0.0019 said to be greater than the 70% ethanol extract content of dayak onion leaves was 2.23% ± 0.0002.

UJI AKTIVITAS EKSTRAK ETANOL 70% DAUN BAWANG DAYAK (Eleutherine palmifolia, (L.) Merr) TERHADAP PERTUMBUHAN Candida albicans Eka Kumalasari; Suci Renita; Dwi Rizki Febrianti; Rakhmadhan Niah
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.824

Eleutherine palmifolia (L.) Merr. Is one of the typical Central Kalimantan plants that has been hereditary used by Dayak people as traditional medicine. Generally, only parts of dayak onion bulbs are used while the onion leaves are often discarded and rarely used. Dayak onion leaves contain chemical compounds that are efficacious as antimicrobials namely alkaloids, flavonoids, saponins, phenols, tannins, triterpenoids and steroids.This type of research is experimental. Using the paper disc diffusion. The purpose of this study was to determine the antifungal activity of 70% ethanol extract of onion leaves on the growth of albicans candida fungi. Eleutherine palmifolia (L.) Merr leaves originating from the Palagka Raya City area of ??Central Borneo. The sample in this study was 70% ethanol extract. The results of this study can be concluded that 70% ethanol extract of dayak onion leaves has activity on the growth of Candida albicans. The diameter of the inhibitory zone in 70% ethanol extract of dayak onion leaves was obtained at a concentration of 100% 21.6 mm, a concentration of 80% 17.45 mm, a concentration of 60% 13.35 mm, a concentration of 40% 10.67mm, concentration 20% 8.35 mm.

UJI AKTIVITAS EKSTRAK ETANOL KULIT ARI BUAH JENGKOL (Pithcelobium jiringa) SEBAGAI BIOLARVASIDA NYAMUK (Aedes aegypti L.) Noverda Ayuchecaria; Nida Munirah; Amaliyah Wahyuni; Eka Kumalasari; Ratih Pratiwi Sari; Siska Musiam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Larvasida is still the first line in the prevention of Dengue Hemorrhagic Fever (DHF) disease caused by Aedes aegypti L. mosquitoes. Indonesia itself as a tropical country has many beneficial plants, one of which is Pithcelobium jiringa pericarp. Until now, the use of pericarp is still lacking even though jengkol fruit peels contain secondary metabolites such as flavonoids, saponins, tannins and triterpenoids, which have larvacidal effects. The purpose of this study was to determine the activity of ethanol extract of Pithcelobium jiringa pericarp as biolarvasida of Aedes aegypti L. mosquitoes from LC50 values. The treatment concentration used in this study was concentrations of 10%, 30%, and 50%. Temephos 1% is used as a positive control. The concentration was then tested on 20 Aedes aegypti L. larvae. The results showed that there was a treatment effect (sig <0.05) on the number of larval deaths, which from the results of Tuckey's analysis showed that 30% and 50% concentrations and 1% Temephos showed significant differences in the number of test larvae deaths. The results showed that the extract was effective as biolarvasida of Aedes aegypti L. mosquitoes. The results of probit analysis showed LC50 extract to Aedes aegypti L. larvae was 20.4716% which is a low toxin group in aquatic environments.

PROFIL SENYAWA DAN AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN SEPAT (Mitragynaspeciosa) DAN DAUN DADANGKAK (Hydrolea spinosa L.) Rakhmadhan Niah; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Sepat folium (Mitragynaspeciosa) and dadangkak folium (Hydrolea spinosa L.) are plants in South Kalimantan. These plants are often used traditionally to reduce blood sugar and antibacterial levels. The effectiveness is suspected because there is strong antioxidant activity in flavonoid compounds. Flavonoid compounds work through the mechanism of capturing free radicals, reducing oxidative stress. The purpose of this study was to determine the profile of flavonoid compounds of sepat folium and dadangkak folium by test the antioxidant activity with DPPH (1,1-diphenyl-2picrylhydrazyl) method. Extract of sepat folium and dadangkak folium were made by the maceration method using methanol as a solvent. Profiles of flavonoid compounds were obtained quantitatively by the standard solution of quercetin. The extract obtained was tested for antioxidant activity by the DPPH (1,1-diphenyl-2picrylhydrazyl) method. The results showed that the total flavonoid value in methanol solvent was the extract of dadakak folium is 51.19 mg QE / g extract and extract of sepat folium is 43.25 mg QE / g extract. Very strong antioxidant activity (<50 ÃƒÅ½Ã‚Â¼g / mL) was found in methanol extracts of sepat folium with a value of 34.70 ÃƒÅ½Ã‚Â¼g / mL and methanol extracts of dadangkak folium with a value of 38.41 ÃƒÅ½Ã‚Â¼g / mL.

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN BAWANG DAYAK (Eleutherine Palmifolia L. Merr) TERHADAP KADAR GULA DARAH MENCIT PUTIH (Mus muscullus) YANG DIINDUKSI GLUKOSA Eka Kumalasari; Syifa Maharani; Aditya Maulana Perdana Putra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Diabetes Mellitus (DM) is a collection of metabolic symptoms that arise in a person caused by an increase in blood glucose due to damage to insulin secretion or resistance to insulin or both. Diabetes mellitus medication can be either parenteral or oral which can cause side effects in long-term use such as mild diarrhea, bloating, fatigue acidosis, even hypoglycemic renal impairment. To prevent it can use alternative medicine using Dayak onion (Eleutherine palmifolia (L) Merr.). One of the active substances contained in the Dayak onion is the flavonoids. Flavonoids have antidiabetic activity through their functions as antioxidants. The study aims to determine the activity of Dayak scallion Extract (Eleutherine palmifolia (L) Merr.) To decrease blood sugar levels (Mus muscullus), which is glucose-induced. The research was conducted with research draft pre and post test with control group design. The mice used amounted to 25 male white mice that were divided into 5 groups i.e. negative control (CMC Na 0.5%), control positive (Glibenklamid 3 mg/kgBB), Dayak onion-leaf ethanol extract at a dose of 50 mg/kgBB, 100 mg/kgBB and 200 mg/kgBB. Observations of the decrease in blood sugar levels of each test group were conducted on the same day, 30 minutes, 60 and 90 after hyperglycemia. Results showed that Dayak onion leaves ethanol extract had activity as a lowering of blood sugar levels in glucose-induced white mice

KARAKTERISASI SIMPLISIA DAN EKSTRAK KULIT BATANG SEKILANG (Embelia borneensis Scheff.) Risa Supriningrum; Reksi Sundu; Triswanto Sentat; Rakhmadhan Niah; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

The Sekilang plant (Embelia borneensis Scheff.) Is one of the plants used by the Dayak community for fishing, leech repellent and as an ingredient for hair care. Empirical use of plants can be developed into products based on natural ingredients. This must be supported by research data. As a first step, the simplicia and ethanol extract of the stem bark were characterized. The research objective was to determine the specific and non-specific characteristics of the simplicia and the extracts of the bark of the sekilang. The research stage includes plant determination, collection of raw materials, manufacture of simplicia, extract preparation, organoleptic, microscopic testing, phytochemical screening, determination of water soluble extract content, determination of ethanol soluble extract content, determination of water content and determination of ash content. Microscopy test results of sekilang stem bark showed the presence of fiber fragments, stone cells, and oxalate crystals. The average water soluble content for simplicia and sekilang bark extract was 7.5% and 80%. The average ethanol soluble content for simplicia and extract was 6% and 30%. The average moisture content for the simplicia and extract was 9.5% and 12%. The mean total ash content for simplicia and extract was 5% and 8.5%. The mean acid insoluble ash content for simplicia and extract was 1% and 0.5%.

EVALUASI PROSEDUR PENYIMPANAN DAN PENDISTRIBUSIAN SEDIAAN FARMASI DAN BAHAN MEDIS HABIS PAKAI DI PUSKESMAS PEKAUMAN BANJARMASIN Noor Aisyah; Eka Kumalasari; Merina Hariani; Rina Feteriyani
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.927

Storage and distribution are management activities of pharmaceutical preparations and medical consumables in storing and distributing to pharmaceutical service sub-units to avoid expired date. The purpose of this study was to determine the procedure and the percentage of suitability of storage and distribution of pharmaceutical preparations and medical consumables at Banjarmasin's Pekauman Health Center. This type of research is non - experimental with descriptive observative. Data collection using the prospective method. The population in this study is the room and all data storage and distribution of pharmaceutical preparations and medical consumables, with saturated sampling period March-April 2020. The research data was observed for qualitative results and calculated by percentage analysis for quantitative results. The results showed that the storage procedures for pharmaceutical preparations and BMHP were 90% in accordance with the Technical Guidebook for Pharmaceutical Service Standards in Puskesmas and 86.11% in accordance with the Checklist for Quality Assurance of Pharmaceutical Services in Basic Health Services. And the procedures for distributing pharmaceutical preparations and medical consumables at the Banjarmasin Pekauman Health Center 100% in accordance with the Technical Guide to Pharmaceutical Services Standards at the Health Center and the Quality Assurance Checklist for Pharmaceutical Services in Basic Health Services.

Penetapan Kadar Flavonoid Ekstrak dan Fraksi Kulit Buah Citrus reticulata Siska Musiam; Erna Prihandiwati; Eka Kumalasari; Aisyah Aisyah
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1343

Citrus reticulata is one of the varieties of citrus endemic to South Kalimantan. So far, the people of South Kalimantan have only used the pulp of the citrus fruit, while the skin is disposed of as waste. Therefore, this study was conducted to see the value of the benefits of the Citrus reticulata rind waste by testing the levels of flavonoids from the extract and its fractions. The rind extraction of Citrus reticulata was carried out by maceration method using methanol as a solvent. The extract obtained was then fractionated using the liquid-liquid method using n-hexane, chloroform, ethyl acetate, and water as solvents. The extract and each fraction were determined for the level of flavonoids using a UV-Visible spectrophotometer at a wavelength of 413 nm and a series of standard concentrations of quercetin 35; 50; 65; 80; and 95 ppm. The results showed that the levels of flavonoids from the highest to the lowest were in the water fraction, methanol extract, n-hexane fraction, ethyl acetate fraction, and chloroform fraction with the respective values of 53.635 ± 0.00697; 30.083 ± 0.00386; 15,524 ± 0.00423; 9.787 ± 0.00198%(w/w).

EVALUASI PROSEDUR PENYIMPANAN DAN PENDISTRIBUSIAN SEDIAAN FARMASI DAN BAHAN MEDIS HABIS PAKAI DI PUSKESMAS PEKAUMAN BANJARMASIN Noor Aisyah; Eka Kumalasari; Merina Hariani; Rina Feteriyani
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.927

Storage and distribution are management activities of pharmaceutical preparations and medical consumables in storing and distributing to pharmaceutical service sub-units to avoid expired date. The purpose of this study was to determine the procedure and the percentage of suitability of storage and distribution of pharmaceutical preparations and medical consumables at Banjarmasin's Pekauman Health Center. This type of research is non - experimental with descriptive observative. Data collection using the prospective method. The population in this study is the room and all data storage and distribution of pharmaceutical preparations and medical consumables, with saturated sampling period March-April 2020. The research data was observed for qualitative results and calculated by percentage analysis for quantitative results. The results showed that the storage procedures for pharmaceutical preparations and BMHP were 90% in accordance with the Technical Guidebook for Pharmaceutical Service Standards in Puskesmas and 86.11% in accordance with the Checklist for Quality Assurance of Pharmaceutical Services in Basic Health Services. And the procedures for distributing pharmaceutical preparations and medical consumables at the Banjarmasin Pekauman Health Center 100% in accordance with the Technical Guide to Pharmaceutical Services Standards at the Health Center and the Quality Assurance Checklist for Pharmaceutical Services in Basic Health Services.

KORELASI ANTARA KADAR GULA DARAH DENGAN KUALITAS HIDUP PASIEN DIABETES MELLITUS DI FASILITAS PELAYANAN KESEHATAN PRIMER Yumassik, Abdul Mahmud; Alfian, Riza; Riski, Akhmad; Soraya, Soraya; Ayu, Welinda Dyah; Rianto, Leonov; Eka Kumalasari
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.989

Diabetes mellitus is a metabolic symptom caused by an increase in blood glucose due to impaired insulin secretion, insulin resistance, or both. Blood glucose levels above the normal limit have an influence on the quality of life of diabetes mellitus patients. The study was conducted with a cross sectional design. Data collection was carried out prospectively during the period from May to June 2022. The sample in this study was patients with diabetes mellitus in one of the primary health care centers in Banjarmasin City. Quality of life data was collected using the EQ-5D questionnaire, while blood glucose levels data was obtained from medical record patient. A total of 75 samples participated in this study. The results showed that the mean fasting blood sugar level was 162,95 mg/dL. The mean value of the sample's quality of life score based on the EQ-5D index was 0,739. There is a significant correlation between blood glucose levels and the quality of life of patients with diabetes mellitus. The results of the correlation indicated that the lower the blood glucose level of patients with diabetes mellitus, the higher their quality of life.

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