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All Journal Jurnal Insan Farmasi Indonesia Proceeding of Mulawarman Pharmaceuticals Conferences Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Medical Laboratory Journal Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Ikifa
cikra ikhda Nur Hamidah safitri
Akademi Farmasi Mitra Sehat Mandiri Sidoarjo
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Physics Public Health

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Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Herbal Ekstrak Temu Kunci (Boesenbergia pandurata Roxb) : Formulation and Physical Quality of Temu Kunci (Boesenbergia pandurata Roxb) as Toothpaste Reza Alfian Ardianto; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.939 KB) | DOI: 10.25026/mpc.v13i1.471

Abstract

Dental caries is one of the oral and dental problems in Indonesia. One of the causes of dental caries is the accumulation of dental plaque which is caused by food residue that sticks to the teeth and undergoes fermentation by the bacteria Streptococcus mutans. Temu Kunci (Boesenbergia pandurata Roxb) is one of Indonesia's native plants which contains flavonoids, tannins and saponins which can inhibit bacterial growth. The purpose of this study was to formulate the extract of temu Kunci (Boesenbergia pandurata Roxb) into a toothpaste preparation and the physical quality of these preparations. The key extract was obtained by maceration method using 96% ethanol as a solvent. Divided into several toothpaste preparations made with the concentration of extract of temu Kunci (Boesenbergia pandurata Roxb) FI 2%, FII 4%, FIII 6% with uniform toothpaste. Evaluation of dental preparations including homogeneity, organoleptic, pH, dispersibility and foam height tests. The test results of the three formulations of dental preparations showed that the three formulations were homogeneous, there was no organoleptic change, the pH range of toothpaste from 6.5 to 8.0 which fulfilled the pH requirements of toothpaste according to SNI 12-3524-1995 were 4.5 - 10, 5, the spreadability test of 6.5 to 8.0 cm, and the test of the height range of the foam from 6.6 to 8.3 cm.
Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Ekstrak Biji Jintan Hitam (Nigella sativa): Formulation and Physical Quality Test of Toothpaste from Black Cumin Seeds (Nigella sativa) Vika Novia Agustyani; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.782 KB) | DOI: 10.25026/mpc.v13i1.472

Abstract

Black Cumin seeds (Nigella sativa) have antibacterial activity because they contain thymoquinones, tannins, saponanins, and flavonoids. According to (Sinaga, 2018) black cumin seeds can inhibit the Streptococcous mutans bacteria that causes dental caries. The research conducted was experimental. The thick extract of black cumin seeds (Nigella sativa) is formulated into toothpaste by varying the concentration of the viscous extract of black cumin seeds (Nigella sativa). The concentration of the active substance used was 0% in the control formula, 2% in formula I, 4% in formula II, 6% in formulation III. Then performed a physical stability test of the toothpaste preparation consisting of homogeneity, pH, high foam, dispersibility, color, odor, and taste. The test was carried out for 28 days of storage. During 28 days of storage all formulations were stable, homogeneity, pH and high foam preparation were stable and met the standards. The particles are evenly distributed so that the preparation has a stable color, smell and taste. The thick extract of black cumin seeds (Nigella sativa) can be formulated into a toothpaste preparation that is stable and meets the requirements. The most stable formulation is formulation I with a concentration of 2% viscous black cumin seed (Nigella sativa) extract.
Formulasi dan Uji Mutu Fisik Sabun Padat Ekstrak Kulit Nanas (Ananas comosus L.): Formulation and Physical Quality Test of Pineapple Peel Extract (Ananas comosus L.) Solid Soap Milani Agustina Putri; Elly Purwati; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.941 KB) | DOI: 10.25026/mpc.v13i1.479

Abstract

Nanas (Ananas comosus L.) merupakan salah satu tanaman di indonesia yang sangat berpotensi untuk dikembangkan karena mempunyai banyak manfaat. Nanas mengandung banyak vitamin B12, vitamin C, vitamin E dan enzim bromelin. Sedangkan kulit nanas yang hanya dianggap sampah yang tidak memiliki manfaat, padahal kulit nanas mengandung enzim bromelin, karotenoid, vitamin C dan flavonoid yang baik bagi kesehatan. Kandungan flavonoid dalam kulit nanas dapat dimanfaatkan sebagai antioksidan, anti alergi, anti inflamasi, dan anti bakteri. Antioksidan kulit nanas dapat dimanfaatkan sebagai pelindung kulit karena dapat mencegah terjadinya radikal bebas dan dapat diaplikasikan dalam bentuk sediaan sabun padat. Penelitian ini bertujuan untuk menghasilkan sabun padat ekstak kulit nanas dan menguji mutu fisik sesuai Standar Nasional Indonesia (SNI). Metode penelitian ini bersifat eksperimental yang terdiri dari pembuatan simplisia dan ekstraksi menggunakan metode maserasi dengan pelarut etanol 70%. Formulasi menggunakan ekstrak kulit nanas dengan konsentrasi 0% (basis), 1% (F1), 3% (F2). Evaluasi karakteristik fisik sabun padat meliputi pengamatan organoleptis, pengujian homogenitas, uji pH, uji daya busa. Sediaan di evaluasi selama 4 minggu, data dianalisis secara deksriptif. Hasil penelitian ini menunjukkan ke tiga formula menghasilkan sabun padat yang homogen, bertekstur padat dan halus, beraroma wangi, Basis (berwarna putih pekat kekuningan), F1 (berwarna putih pekat kekuningan), F2 (berwarna putih pekat kekuningan). Nilai pH pada basis, F1, F2 adalah 9,52 ,9,35, 9,45. Hasil organoleptis pada sediaan sabun padat basis, F1, F2 tidak mengalami perubahan. Nilai homogenitas pada sabun padat basis, F1, F2 tidak mengalami perubahan. Nilai uji daya busa sabun padat basis, F1, F2 tetap stabil. Kesimpulan pada penelitian ini yaitu mutu fisik sediaan sabun padat ekstrak kulit nanas memenuhi syarat SNI dan stabil selama penyimpanan 4 minggu.
PEGARUH VARIASI KONSETRASI BAHAN PENGIKAT PVP (Polyvinyl Pyrrolidone) TERHADAP MUTU FISIK TABLET KUNYIT (Curcuma domestica Val.) cikra ikhda safitri; Yeyen Dwi Aprilia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 4 No 2 (2020)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v4i2.130

Abstract

Diabetes Melitus (DM) adalah suatu penyakit kronis dan Indonesia merupakan peringkat ke-6 di dunia. Kunyit (Curcuma domestica Val.) mengandung 75% curcumin yang memiliki aktivitas sebagai antidiabetes. Penelitian ini bertujuan untuk memformulasikan tablet kunyit menggunakan metode granulasi basah dengan varian konsentrasi bahan pengikat 2,5% (F1) dan 5% (F2). Penelitian ini terdiri dari pembuatan simplisia, pembuatan ekstrak, pembuatan granul dengan variasi konsentrasi bahan pengikat 2,5% dan 5%, pencetakan tablet dengan cetak tablet single punch serta uji mutu fisik tablet. Tablet yang dihasilkan dilakukan pegujian mutu fisik yang meliputi uji keseragaman bobot, uji keseragaman ukuran, uji kekerasan tablet, uji waktu hancur tablet dan uji kerapuhan tablet. Analisis hasil menggunakan bantuan software SPSS dengan uji statistik non-parametric 2-independent sample atau mann whiteney U. Hasil uji mutu fisik tablet yang meliputi uji keseragaman bobot dengan hasil rata-rata F1 dan F2 adalah 320,75±3,56 dan 307,80±0,98. Uji keseragaman ukuran dengan rata-rata diameter F1 dan F2 adalah 1,00±0,00 dan 1,10±0,00, sedangkan rata-rata tebal F1 dan F2 adalah 0,31±0,00 dan 0,28±0,00. Uji kekerasan tablet dengan hasil rata-rata F1 dan F2 adalah 1,00±0,00. Uji waktu hancur tablet dengan hasil rata-rata F1 dan F2 adalah 840 detik dan 816 detik dan uji kerapuhan tablet dengan hasil rata-rata F1 dan F2 adalah 0,10±0,02 dan 0,26±0,00. Hasil uji statistik menunjukkan bahwa ada perbedaan yang signifikan diakibatkan karena adanya pengaruh dari perbedaan variasi konsentrasi bahan pengikat pada mutu fisik tablet berupa keseragaman bobot tablet dan waktu hancur tablet (sig <0,05).                                                                                           Kata kunci : Kunyit, diabetes melitus, tablet, Polyvinyl pyrrolidone (PVP)
PEMERIKSAAN FISIK, TEKANAN DARAH, GULA DARAH, DAN ASAM URAT DI PELAYANAN SOSIAL TRESNA WERDHA JOMBANG 2021 Zuanta Pangestuti; Cikra Ikhda Nur Hamidah Safitri; Yoehania Yoehania
Jurnal Pengabdian IKIFA Vol. 1 No. 1 (2021): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pelayanan Sosial Tresna Werdha (PSWT) Jombang is part of the East Java Provincial Social Service which provides social services for clients, namely neglected elderly (elderly) aged 60 (sixty) years and over, administration and community services. Health problems faced by the elderly in PSWT today include Rheumatic, Hypertension and Diabetes Mellitus. The implementation of community service activities is carried out to provide health check services and free treatment to maintain the health of PSWT clients. The method in this activity is to do a physical examination of the client then given treatment and counseling. The target in the implementation of this community service is PSWT clients. The result of this activity is that it is known that the client has an increase in blood sugar levels, uric acid and high blood pressure. In addition, there are clients who have had a stroke. The complaints felt by the majority of clients are back pain, knees and dizziness. The conclusion of this activity is that clients at PSTW get free health checks and treatment equally.
FORMULASI DAN UJI MUTU FISIK SEDIAAN LOTION DARI EKSTRAK DAUN NANAS (Ananas comosus (L).Merr) Cikra Ikhda Nur Hamidah Safitri; Qholindah Qumairo Vidya Zahra
Jurnal Insan Farmasi Indonesia Vol 9 No 1 (2026): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v9i1.2888

Abstract

Pineiapplei leiaveis (Ananas comosuis (L.) Meirr) is known as a natuiral ingreidieint that contains variouis bioactivei compouinds with thei poteintial for antioxidant activity, so it has thei opportuinity to bei uiseid in thei deiveilopmeint of topical cosmeitic preiparations. This reiseiarch aims to deiveilop a lotion formuilation that contains pineiapplei leiaf eixtract and asseiss thei physical quiality of thei reisuilting preiparation. Thei eixtraction proceiss is carrieid ouit by maceiration meithod uising 70% eithanol solveint and produiceis a yieild of 7,028%. Lotion is formuilateid in threiei variations, nameily F0 withouit thei addition of eixtract as a control, F1 with 1% eixtract conceintration, and F2 with 3% conceintration. Physical quiality teisting incluideis pH eivaluiation, organoleiptic propeirtieis, spreiadability, viscosity, and homogeineiity. Phytocheimical screieining reisuilts show thei preiseincei of flavonoid compouinds, alkaloids, and tannins in pineiapplei leiaf eixtract. Thei eintirei formuila meieits thei physical quiality reiquiireimeints of topical preiparations, shown by a pH valuiei that is suiitablei for thei skin condition, spreiading poweir and viscosity that meieits thei standard, as weill as good homogeineiity withouit phasei seiparation. Thei addition of pineiapplei leiaf eixtract doeis not reiduicei thei physical stability of thei preiparation, so it has thei poteintial to bei fuirtheir deiveilopeid as a natuiral activei ingreidieint in skin carei lotion formuilations.
Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Kulit Buah Naga (Hylocereus Polyrhizus) terhadap Pertumbuhan Jamur Candida Albicans Secara in Vitro Zakiyatul Hamida; Panji Ratih Suci; Erna Fitriany; Cikra Ikhda Nur Hamidah Safitri; Nurfitriyawatie Nurfitriyawatie
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 3 (2024): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i3.287

Abstract

Dandruff is one of the problems that cause a lack of confidence. The triggering microorganism is Candida albicans. The innovation in the skin of red dragon fruit has the potential as an antibacterial and antifungal because it contains several active compounds such as alkaloids, terpenoids and flavonoids. This study aims to find out at what concentration the anti-dandruff activity on the growth of Candida albicans fungus in the formulation of dragon fruit peel extract shampoo preparation (Hylocereus polyrhizus). This research method is an experimental research using the disc paper diffusion method which consists of making dragon fruit peel extract with the maceration method using 96% ethanol solvent. The extract is formulated in shampoo with concentrations of 20.40 and 80%. The results of this study were in the organoleptis test in the form of a viscous liquid, soft sticky texture, brown and menthol flavor. pH test 6.13, 6.71, 6.39, 5.49. Test the height of the foam 5.8cm, 6.0cm, 6.5cm, 10.3cm. Viscosity test 500 Cp, 612 Cp, 635 Cp, 624 Cp. Homogeneity test is homogeneous. Anti-dandruff shampoo activity test of kontro (+), control (-), concentration of 20%, 40%, 80% with an average of 21.95 mm, 0.00 mm, 22.9 mm, 26.07 mm, 28.52 mm. The conclusion of this study is that the formulation of dragon fruit peel extract shampoo (Hylocereus polyrhizus) has provided an inhibitory effect on the growth of Candida albicans fungus with the strongest inhibitory concentration produced in formulation III with a concentration of 80% of 28.52 mm.
Uji Stabilitas Masker Gel Peel Off Kombinasi Sisik Ikan Bandeng Dan Kulit Jeruk Nipis Cikra Ikhda Nur Hamida Safitri; Cahya Tri Miftakhul Jhanna
Calory Journal Medical Laboratory Journal Vol. 2 No. 2 (2024): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v2i2.258

Abstract

The lime plant with the Latin name Citrus Aurantifolia is a plant that grows widely in Indonesia. Lime can also be used as a cough medicine, phlegm buster, influenza medicine, acne medicine and many more. Apart from using natural materials, we also use fish scale waste. Milkfish scales contain 0.3% collagen. The collagen content can be used as anti-aging for the skin. To find out the stability test of the peel off gel mask, a combination of milkfish scales and lime, meets the criteria parameters for cosmetic preparations. The formulation of the peel off gel mask was carried out by modifying the formula into 3 (three) formulas with different concentrations of the extract to be used, namely F1 (1%), F2 (3%) and F3 (5%). This research began with collecting simplicia, extraction, making a peel-off gel mask and stability testing. The stability tests carried out were organoleptic, pH, dry preparation time and spreadability. In accordance with SNI masks 16-6070-1999. The stability test of the preparation was determined by storing the preparation for 21 days at different temperatures. The stability test is based on looking at the changes that occur starting from day 1 to day 21 of storage. The test results of the three peel-off gel mask formulations showed that the three temperatures on day 21 experienced changes in test parameters. The research results were analyzed using the SPSS Anova method.
Co-Authors Adelya Youan Nurdiana Angelica Olsa Okta Rizky Cahya Tri Miftakhul Jhanna Chelsie Onesya Prolapita Chyntia Maharani Deva Rahayu Nurindah Kusuma Wardani Dewinta Hesti Dwi Nurani Elly Purwati Elly Purwati ERNA FITRIANY, ERNA Luluk Jubaidah Milani Agustina Putri Nurfitriyawatie Nurfitriyawatie Panji Ratih Suci Qholindah Qumairo Vidya Zahra Reza Alfian Ardianto Sintya Zagita Sukma Dewi Ayu Anggraini Vika Novia Agustyani Yeyen Dwi Aprilia Yoehania Yoehania Zakiyatul Hamida Zuanta Pangestuti