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All Journal Justek : Jurnal Sains Dan Teknologi Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal AFAMEDIS Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Elly Purwati
Akademi Farmasi Mitra Sehat Mandiri Sidoarjo
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Education Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Public Health

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UJI MUTU FISIK SABUN HERBAL PADAT EKSTRAK KULIT BUAH NAGA (Hylocereus Polyrhizus) Elly Purwati
AFAMEDIS Vol. 2 No. 1 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.102 KB)

Abstract

Buah naga mulai banyak dikonsumsi karena kandungan kimianya yang bermanfaat bagi kesehatan. Namun, tanpa kita sadari selama ini kita menjadikan kulit buah naga menjadi limbah hal itu sama saja membuang berbagai manfaat yang tersimpan di dalamnya. Kulit buah naga mengandung vitamin C, vitamin E, vitamin A, alkaloid, terpenoid, flavonoid, tiamin, niasin, piridoksin, kobalamin, fenolik, karoten, dan fito albumin. Antosianin merupakan senyawa flavonoid yang memiliki kemampuan sebagai antioksidan. Inilah yang menjadi dasar ekstrak kulit buah naga merah dijadikan sebagai zat tambahan pada pembuatan sabun herbal padat. Dan untuk mengetahui karakteristik sabun herbal padat ekstrak kulit buah naga dengan uji mutu meliputi uji organoleptis, uji kesukaan, uji pH, uji stabilitas busa. Kulit buah naga dapat di formulasikan sebagai bahan pembuatan sabun herbal padat ekstrak kulit buah naga denga nmetode maserasi dengan Etanol, pembuatan sabun dengan metodedingin (Cold Process) Hasil uji mutu fisik diperoleh pH 11 dan uji stabilitas busadengan prosentase busa yang hilang 0.22%-0,25% yang telah memenuhi persyaratan mutu sabun padat. Kesimpulan dari penelitian ini adalah ekstrak kulit buah naga dapat diformulasikan menjadi sabun herbal padat dan sabun herbal padat ekstrak kulit buah naga konsentrasi 1% dan 3% sesuai dengan uji mutu fisik sabun menurut SNI yaitu uji organoleptis, uji pH dan uji stabilitas busa.
Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Daun Kelor (Moringa oleifera L.) : Formulation of Physical Quality Test For Moringa Leaf Extract Solid Soap (Moringa oleifera L.) Angelica Olsa Okta Rizky; Elly Purwati; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.188 KB) | DOI: 10.25026/mpc.v13i1.439

Abstract

The leaves of Moringa (Moringa oleifera L.) have the potential as a medicinal plant which can often be used as an alternative for the treatment of various diseases. Besides being able to be processed for food ingredients, Moringa leaves can also be used as an anti-cancer treatment, prevent anemia and can also inhibit the activity of bacteria and fungi. This study aims to produce solid soap for Moringa leaf extract and to test the physical quality according to the Indonesian National Standard (SNI). This research method is experimental which consists of the manufacture of simplicia and extraction using the maceration method with 70% ethanol solvent. formulation using Moringa leaf extract with a concentration of 0% (base), 3% (F1), and 5% (F2). Evaluation of the physical characteristics of solid soap includes organoleptic observation, homogeneity testing, pH test, foam power test. The preparation was evaluated for 4 weeks, the data were analyzed descriptively. The results of this study indicate that a solid soap preparation that is homogeneous, has a dense and smooth texture, has a fragrant aroma, base (white color), F1 (blackish green color), F2 (blackish green color). The average pH value on the basis, F1, F2 is 9.The organoleptic test results on base solid soap preparations, F1, F2 did not change from week 1 to 4. Base solid soap foam power test values, F1, F2 remain stable. The conclusion of this research is that the physical quality of the Moringa leaf extract solid soap meets the SNI requirements.
Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Daun Tin (Ficus carica L.) Andri Priyoherianto; Elly Purwati; Erna Fitriany
Justek : Jurnal Sains dan Teknologi Vol 6, No 3 (2023): September
Publisher : Unversitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/justek.v6i3.17296

Abstract

The content of flavonoid compounds in tin leaves has the potential to be an alternative source of natural antioxidants. The purpose of this study was to determine the formulation and physical quality test of tin leaf extract solid soap preparations. This research method is an experimental research and method of making soap using the cold process method. Making tin leaf extract solid soap by collecting the ingredients to be extracted using the maceration method with 70% ethanol solvent, carrying out formulations with extract concentrations of 0% 1% and 3% and evaluating the physical quality of solid soap preparations which include organoleptic tests, pH tests, homogeneity test and foam height test on tin leaf extract solid soap. Organoleptic test of solid soap F0 produces a light green color with black mystique perfume, F1 produces a dark green color with black mystique perfume, F2 produces a brownish green color with strawberry perfume. The pH value obtained, which is 9, meets the requirements, the pH range for solid soap for the skin is 9-11. The homogeneity test showed that the fig leaf extract herbal soap with a concentration of 1% and 3% showed no spots, therefore the fig leaf solid soap fulfilled the homogeneity requirements. The soap foam height test showed that soap produced foam (F0= 9.16Ccm, F1= 8cm, F2= 8.16cm).
EFFECTIVENESS PROFILE OF AMLODIPINE AND LISINOPRIL IN HYPERTENSION OUTPATIENTS AT PRATAMA CLINIC SIDOARJO Andri Priyoherianto; Elly Purwati; Erna Fitriany; Husna
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.941

Abstract

Hypertension is the leading cause of premature death worldwide. An estimated 1.28 billion  adults aged 30-79 years worldwide have hypertension. Treatment of hypertension is usually aimed at preventing morbidity and mortality from hypertension. The choice of drugs for each patient's hypertension depends on the metabolic and subjective side effects caused. This study aims to determine the effectiveness profile of antihypertensive drugs amlodipine 10 mg or lisinopril 10 mg in outpatients at the Sidoarjo Pratama Clinic for January- March 2023. This research method is observational, with a cross-sectional approach and data collection. Quantitative analysis was then done using the statistical program SPSS 24 with univariate analysis. The results of the independent t-test showed a significance value for the systolic category of 0.780 > 0.05 and a significance value for the diastolic category of 0.931 > 0.05. Patients receiving therapy with amlodipine 10 mg or lisinopril 10 mg reached the target in 30 patients. After doing the independent t-test before and after therapy in both the systolic category and the diastolic category, it can be concluded that there is no significant difference in the effectiveness of the two groups. Keywords: Amlodipine, Blood Pressure, Hypertension, Lisinopril
AKTIVITAS ANTIBAKTERI SABUN PADAT EKSTRAK KULIT BUAH NANAS (Ananas comosus L.) PADA Escherichia coli Elly Purwati; Sih Wahyuni Raharjeng
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.670

Abstract

Pineapple skin is available in abundance, as much as 50-70% of pineapple fruit. However, this fruit peel is simply thrown away as waste, whereas pineapple peel contains many bioactive compounds such as flavonoids, carotenoids, alkaloids, saponins, and vitamin C. These compounds have various properties, one of which functions as an antibacterial. The purpose of this study was to determine the antibacterial activity of solid soap extract from pineapple peel (Ananas comosus L) with a concentration of 1% and 3% on Escherochia coli. The research method was experimental, making solid soap from pineapple peel extract 1% (F1) and 3% (F2). The extraction method was carried out using 70% ethanol solvent maceration and the bacterial inhibition test using disk diffusion. Chloramphenicol as a positive control. In conclusion, solid soap of pineapple peel extract (Ananas comosus L.) concentration of 3% is more effective than 1% in inhibiting Escherichia coli bacteria with an average inhibition zone of 20.5 mm, SPSS One Way Anova data states a value of 0.016 <0.05 which indicates there is a significant difference.
Co-Authors Andri Priyoherianto Angelica Olsa Okta Rizky cikra ikhda Nur Hamidah safitri ERNA FITRIANY, ERNA Husna Sih Wahyuni Raharjeng