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Formulation and Physical Stability Of Raspberry Fruit Extract Shampoo Saprianto Saprianto; Eka Putri Wiyati; Nurwani Purnama Aji; Tri Yanuarto
Journal Medical Informatics Technology Volume 4 No. 3, September 2026
Publisher : SAFE-Network

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37034/medinftech.v4i3.172

Abstract

Raspberry fruit (Rubus rosifolius Sm.) contains bioactive compounds with potential for use in hair care products, but the physical properties and stability of a shampoo containing its extract require evaluation. This study aimed to formulate raspberry fruit extract shampoo and assess the effects of extract concentration on its physical characteristics and stability. The fruit was extracted by maceration with 96% ethanol and incorporated into four shampoo formulations containing 0% (F0), 5% (F1), 10% (F2), and 15% (F3) extract. Organoleptic properties, homogeneity, pH, foam height, viscosity, spreadability, and adhesion were evaluated. Physical stability was assessed over six cycles of alternating storage at 4 ± 2°C and 40 ± 2°C.  Selected parameters were compared before and after the cycling test using paired t-tests. From 500 g of dried material, 114 g of concentrated extract was obtained, corresponding to an extraction yield of 22.8%. All formulations remained visually homogeneous, with pH values ranging from 6.09 to 6.39. Increasing extract concentration was associated with higher viscosity and adhesion and lower spreadability and foam height. Foam height in F2 fell below the study’s stated range in weeks 3 and 4, while F3 remained below it throughout observation. No statistically significant differences were reported between measurements before and after the cycling test for pH, foam height, viscosity, spreadability, or adhesion (p > 0.05). Raspberry fruit extract could be incorporated into shampoo, but further formulation work is needed to improve foam height at higher extract concentrations.
Evaluasi Penggunaan Obat Antiemetik pada Pasien Kanker Serviks yang Menjalani Kemoterapi di RSUD dr. M. Yunus Bengkulu Nur Aini; Nurwani Purnama Aji; Herlin Sulita
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2553

Abstract

Cervical cancer is one of the most common malignancies affecting women and chemotherapy remains an important component of treatment, particularly in advanced or metastatic disease. Chemotherapy-induced nausea and vomiting (CINV) is one of the common adverse effects of chemotherapy that may interfere with nutritional status, hydration, treatment adherence, and quality of life. Appropriate antiemetic therapy is therefore important to support chemotherapy treatment. This study aimed to evaluate the use of antiemetic drugs in cervical cancer patients undergoing chemotherapy at Dr. M. Yunus Hospital, Bengkulu, during 2022–2024. This study used a non-experimental descriptive design with a retrospective approach. Data were obtained from medical records of cervical cancer patients receiving chemotherapy and antiemetic therapy. A total of 75 patients met the inclusion criteria and were evaluated based on patient characteristics, chemotherapy regimens, antiemetic use, and appropriateness of patient, indication, drug, dose, and administration route. The results showed that most patients were aged 51–60 years (37.33%), housewives (70.67%), had senior high school education (66.67%), and were diagnosed with stage IIIB cervical cancer (61.33%). The most frequently used chemotherapy regimen was paclitaxel plus carboplatin (86.67%), while the most commonly administered antiemetic regimen was ondansetron plus dexamethasone (57.33%). Evaluation demonstrated 100% appropriateness for patient, indication, drug, dose, and administration route. These findings indicate that antiemetic use at Dr. M. Yunus Hospital was rational based on the therapeutic guideline used in the study. Periodic evaluation is recommended to maintain the quality and appropriateness of antiemetic therapy.
PERBANDINGAN AKTIVITAS ANTELMENTIKA SEDIAAN SIRUP DAN SUSPENSI EKSTRAK ETANOL DAUN MIANA (Coleus scutellariodes (L) Benth) SECARA IN VITRO nurwani purnama aji; Sri Susanti; Nenni Rahmi Hasibuan
Jurnal Ilmiah Pharmacy Vol 13, No 2 (2026)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v13i2.1066

Abstract