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All Journal Jurnal Surya Medika Jurnal Sinergitas PkM & CSR Jurnal Integrasi Kesehatan dan Sains Indonesia Berdaya Borneo Journal Of Pharmascientech Seminar Nasional Hasil Riset dan Pengabdian (SNHRP) Journal of Pharmaceutical Care and Sciences Innovative: Journal Of Social Science Research
Darini Kurniawati
Universitas Sari Mulia
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Jurnal Surya Medika

 1 
Uji Aktivitas Antioksidan Kombinasi Infusa Daun Sirih (Piper betle L), Ekstrak Etanolik Tanaman Bundung (Actinuscirpus grossus) dan Kulit Jeruk Nipis (Citrus aurantifolia) Kunti Nastiti; Noval Noval; Darini Kurniawati
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2647

Abstract

Piper betle L., the leaf, is the most often used for treatment and has been scientifically proven to have antibacterial activity. Actinuscirpus grossus plants are commonly found in Kalimantan and have antimicrobial properties. Citrus aurantifolia peel has antioxidant effects and nutritious chemical compounds in medicine. The purpose of this study was to determine the effect of antioxidant activity in a combination of Piper betle L., leaf infusion, ethanolic extract of Actinuscirpus grossus plant, and Citrus aurantifolia peel. The research method was experimental by making Piper betle L. leaves infused with water solvent. Simplisia powder of Actinuscirpus grossus plants and Citrus aurantifolia peel extracted by maceration with 95% ethanol solvent. The combination of the three plants was then tested for antioxidants by the DPPH method. Quercetin is used as a positive control. The results showed that the combination of the three plants had moderate antioxidant activity (IC50 128 ppm), but the antioxidant activity was smaller than quercetin (IC50 16.88 ppm). The combination of Piper betle L., leaf infusion, ethanolic extract of Actinuscirpus grossus plant, and Citrus aurantifolia peel has a moderate antioxidant category.
Identifikasi Senyawa Aktif Antibakteri dari Ekstrak Bajakah (Spatholobus Littoralisk Hask) dengan GCMS (Gass Chromatography Mass Spectroscopy): Identification of Active Antibacterial Compounds from Spatholobus Littoralisk Hask Extract With GCMS (Gass Chromatography Mass Spectroscopy) Kunti Nastiti; Dyan Fitri Nugraha; Darini Kurniawati
Jurnal Surya Medika (JSM) Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i1.5195

Abstract

Bajakah wood (Spatholobus Littoralisk Hask) is empirically used by the community to treat stomach pain, diarrhea and is even believed to be able to treat cancer. Several studies have shown its activity as an antibacterial. The purpose of this study was to identify compounds with antibacterial properties using Gas Chromatography Mass Spectroscopy (GCMS). The method used in this research is the experimental method. Bajakah plants were obtained from seven different areas, then extracted and fractionated. The fraction identified in this study was the n-hexan fraction. Preliminary tests were carried out using thin layer chromatography (TLC) bioautography for compounds that have the potential as antibacterial. Compounds in the n-Hexan fraction were further identified using Gass Chromatography Mass Spectroscopy (GCMS). The results showed Bajakah wood from seven regions had antibacterial activity seen from the formation of inhibition zones on compound spots on TLC that had been planted in agar media. There are 23 types of compounds identified by GCMS in this n-hexan fraction. In this study, the dominant compound seen from the largest area was Stigmast-5-en-3-ol, (3.beta.,24S)- (CAS) Clionaster (26.74%). The results of TLC bioautography of the n-Hexan fraction showed antibacterial activity and the dominant compound was Stigmast-5-en-3-ol, (3.beta.,24S)- (CAS) Clionaster.
Antibacterial Activity of Ulin Fruit Extract (Eusideroxylon zwageri) Against Bacteria Causes in Human Infections: Antibacterial Activity of Ulin Fruit Extract (Eusideroxylon zwageri) Against Bacteria Causes in Human Infections Wina Annisa; Dede Mahdiyah; Darini Kurniawati
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5664

Abstract

Infectious diseases one of the main health problem, especially in developing countries and have been recorded to cause more than 3 million people to die every year. Therapy used is antibacterial, but currently there are many occurrences of resistance to antibacterials, for example by the bacteria Salmonella typhi, Escherichia coli, and Staphylococcus aureus so it’s necessary to find antibacterial alternatives to treat infectious diseases. Non-pharmacological therapy used is the Ulin plant (Eusideroxylon zwageri), such as it’s fruit which contains secondary metabolites that function as antibacterial. This research aimed to identify the antibacterial activity of the Ulin fruit extract against Salmonella typhi, Escherichia coli, and Staphylococcus aureus bacteria. The type of research used is True Experimental with a Posttest-Only Control Group design. Screening antibacterial activity of Ulin fruit extract against Salmonella typhi, Escherichia coli, and Staphylococcus aureus bacteria using the well diffusion method and determining antibacterial activity test using the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) methods, then the data were analyzed using One Way Anova Test. The results show Ulin fruit extract has antibacterial activity with highest inhibition zone at concentration of 10 mg/ml against Salmonella typhi 19,07 mm, Escherichia coli 12,57 mm, and Staphylococcus aureus 12,31 mm and each has strong antibacterial activity. MIC at concentration of 5mg/ml. The results of statistical analysis showed significance value of 1,000 (p>0.05), meaning that there was no significant difference. So, Ulin fruit extract (Eusideroxylon zwageri) has antibacterial activity with a Minimum Inhibitory Concentration (MIC) value of 5mg/ml.
Hubungan Tingkat Pengetahuan Orang Tua Terhadap Perilaku Penggunaan Antibiotik pada Balita ISPA di Wilayah Kerja Puskesmas Buntok: The Correlation Between Parent’s Knowledge Level and Antibiotic Use in Ari Patients in Buntok Health Center Area Shopa Handayani; Darini Kurniawati; M. Zulfadhilah
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5666

Abstract

Background: The problem of ARI has tended to increase in recent decades, both globally and nationally. The high prevalence of ARI and its impact has resulted in the high consumption of antibiotics. The lack of knowledge on antibiotics tends to lead to inappropriate use of antibiotics. Objective: to analyze the correlation between the level of parental knowledge and the use of antibiotics in children with ARI in the Buntok Health Center area. Methods: Research in the Buntok Community Health Center in August 2020. The type of research was analytic survey with cross sectional approach. Population and sample were parents of children under five diagnosed with ARI and receiving antibiotic therapy at Buntok Health Center. The sample part of the population was 30 people with accidental sampling technique. The instrument was a questionnaire using the google form method. Data analysis using spearman rank. Results: Most of the parents of children under five with ARI had less knowledge about antibiotics as many as 17 people (56.6%) and most of the use of antibiotics was in the moderate category, namely 23 people (76.7%). There is a relationship between parental knowledge and the use of antibiotics in children with ARI in the working area of ​​Buntok Health Center (p value = 0.000). Conclusion: Puskesmas Buntok can improve health education, for example by distributing leaflets about ARIs and the use of ARI antibiotics.
Co-Authors Adriana palimbo Ani Agustina Ashiela Ashiela Dede Mahdiyah Dedek Yahya Darmadi Dyan Fitri Nugraha Fachry Abda El Rahman Iwan Yuwindry Karlina Karlina Kunti Nastiti Muhammad Zulfadhilah Noval Noval Novita Dewi Iswandari Sariyasih Sariyasih Shopa Handayani Siti Malahayati Sri Suhartini Tuti Alawiyah Wina Annisa