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Journal : Journal of Pharmaceutical Care and Sciences

Studi Rasionalitas Penggunaan Antibiotika di RSUD DR. Murjani Sampit darini kurniawati
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.765 KB) | DOI: 10.33859/jpcs.v2i1.70

Abstract

Background Antibiotics are the most widely used type of drug due to the high incidence of infection in Indonesia. From the results of the preliminary study for 3 days prospectively, as many as 44 patients who received treatment, 37 patients (87%) received antibiotic therapy. There is the use of expensive antibiotics from the 3rd generation cephalosporin group, there are 4 trade names, 2 generation cephalosporins and 1 there are 6 trade names. Expensive sulbenicin and aminoglycoside derivatives are also found, Gentamicin and Kanamycin. The relatively cheap antibiotics are chloramphenicol, tetracycline, cotrimoxazole, but various brands of these products are popular with "me too drug" being used, of course with varying prices. Government Hospital type C should refer to the use of generic drugs and refer to the national antibiotic use guidelines. Therefore, researchers want to investigate further. Objective To study the patterns of antibiotic use at the Dr Murjani Sampit Regional Hospital before and after the Educational Information Communication on Guidelines for the Use of National Antibiotics. Method This study used a retospective and prospective descriptive observational study with pre-research intervention to medical personnel on the Guidelines for the Use of National Antibiotics and Rational Pharmacotherapy, to paramedics on the stability and method of administering injection dosage antibiotics. This retrospective study used medical documents for patients at 3 months intervals from inpatients for Surgery, Internal Medicine, Children and Gynecology. Prospective study of inpatients at the UPF Surgery, Internal Medicine, Children, and Gynecology for 1 week. Analysis of antibiotic prescribing patterns and the rationality of using antibiotics based on the National Antibiotic Guidelines and Use references. Results The distribution pattern of antibiotic use from a retrospective study of 447 patients, there were 260 (58.1%) patients using antibiotics. Even in obstetrics UPF, 100% of the gynecologists used antibiotics. The results of a retrospective study on the rational category and the cost of using antibiotics found the rationality of the indications and patients only reached <50% of the 4 UPFs studied. The rationality of the dosage regimen was <20% and the dose regimen <10%. Average cost of antibiotics wasted Rp. 80,374 per patient. The highest wastage was at UPF Obstetrics and Gynecology of Rp. 145,223/patient, while the lowest was in UPF Children of Rp. 40,837,-/ patient. From the prospective study, there were 260 patients, 100% used antibiotics with the rationality of the indications and the patients <50%, the rationality of the drug selection was <20%, the rationality of the dosage regimen was <10%. The average wasted cost of antibiotics which became a burden for patients was Rp. 74,793,-/patient with the highest waste at the UPF Gynecology Rp. 119,272,-/patient and the lowest in UPF Children was Rp. 34,697,-/patient. Conclusion The pattern of antibiotic use in Dr Murjani Sampit Hospital in the 4 UPFs studied was 49.1 - 100%. There was an irrational use of antibiotics, the right indication was <43%, the right drug selection was <37.7%, the right dose regimen was <20.8%, there was a combination of antibiotic interactions <6.9% and there was a waste from the use of antibiotics Rp. 80,374,-/patient in retrospective and Rp. 74,793,-/patient in the prospective study. Keywords Rationality, Antibiotics
S Studi Rasionalitas Penggunaan Antibiotika di RSUD DR. Murjani Sampit darini kurniawati
Jurnal Pelayanan Kefarmasian dan Sains Vol 1 No 2 (2021): Journal Pharmaceutical Care and Sciences
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.70

Abstract

Background: Antibiotics are the most widely used type of drug due to the high incidence of infection in Indonesia. From the results of the preliminary study for 3 days prospectively, as many as 44 patients who received treatment, 37 patients (87%) received antibiotic therapy. There is the use of expensive antibiotics from the 3rd generation cephalosporin group, there are 4 trade names, 2 generation cephalosporins and 1 there are 6 trade names. Expensive sulbenicin and aminoglycoside derivatives are also found, Gentamicin and Kanamycin. The relatively cheap antibiotics are chloramphenicol, tetracycline, cotrimoxazole, but various brands of these products are popular with "me too drug" being used, of course with varying prices. Government Hospital type C should refer to the use of generic drugs and refer to the national antibiotic use guidelines. Therefore, researchers want to investigate further. Objective: To study the patterns of antibiotic use at the Dr Murjani Sampit Regional Hospital before and after the Educational Information Communication on Guidelines for the Use of National Antibiotics. Method: This study used a retospective and prospective descriptive observational study with pre-research intervention to medical personnel on the Guidelines for the Use of National Antibiotics and Rational Pharmacotherapy, to paramedics on the stability and method of administering injection dosage antibiotics. This retrospective study used medical documents for patients at 3 months intervals from inpatients for Surgery, Internal Medicine, Children and Gynecology. Prospective study of inpatients at the UPF Surgery, Internal Medicine, Children, and Gynecology for 1 week. Analysis of antibiotic prescribing patterns and the rationality of using antibiotics based on the National Antibiotic Guidelines and Use references. Results: The distribution pattern of antibiotic use from a retrospective study of 447 patients, there were 260 (58.1%) patients using antibiotics. Even in obstetrics UPF, 100% of the gynecologists used antibiotics. The results of a retrospective study on the rational category and the cost of using antibiotics found the rationality of the indications and patients only reached <50% of the 4 UPFs studied. The rationality of the dosage regimen was <20% and the dose regimen <10%. Average cost of antibiotics wasted Rp. 80,374 per patient. The highest wastage was at UPF Obstetrics and Gynecology of Rp. 145,223/patient, while the lowest was in UPF Children of Rp. 40,837,-/ patient. From the prospective study, there were 260 patients, 100% used antibiotics with the rationality of the indications and the patients <50%, the rationality of the drug selection was <20%, the rationality of the dosage regimen was <10%. The average wasted cost of antibiotics which became a burden for patients was Rp. 74,793,-/patient with the highest waste at the UPF Gynecology Rp. 119,272,-/patient and the lowest in UPF Children was Rp. 34,697,-/patient. Conclusion: The pattern of antibiotic use in Dr Murjani Sampit Hospital in the 4 UPFs studied was 49.1 - 100%. There was an irrational use of antibiotics, the right indication was <43%, the right drug selection was <37.7%, the right dose regimen was <20.8%, there was a combination of antibiotic interactions <6.9% and there was a waste from the use of antibiotics Rp. 80,374,-/patient in retrospective and Rp. 74,793,-/patient in the prospective study. Keywords Rationality, Antibiotics
Studi Farmakovigilans Obat Herbal Di Kota Banjarmasin Dengan Metode Naranjo Darini Kurniawati; Iwan Yuwindry
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 1 (2021): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i1.132

Abstract

Background: Basic Health Research of the Republic of Indonesia in 2018 obtained data that 30.4% of Indonesian people consume traditional herbal medicine in homemade ingredients. The Indonesian government encourages the use of herbs because the raw materials for finished drugs are still obtained from abroad (Dani Pratama, 2020). The purpose of this study was to see the possibility of side effects on the use of herbal medicines for the people of Banjarmasin using the Naranjo method. This research method is descriptive observational with a cross sectional design with purposive sampling with inclusion and exclusion criteria set by researchers in the North Banjarmasin District. Data analysis using Naranjo. The results of the research from the dominant age characteristics data are aged 31-50 years as many as 13 (42%), the majority gender is 22 (71%), the majority of the work status is self-employed 19 (61 %), the majority of the education status is SMA 15 (48 %), majority income status above two million 10 (32 %). The majority of people use herbal medicines 27 (87%), sources of information on herbal medicines from families 20 (65%), the majority of herbal medicines are from traditional medicine shops 11 (35%), the majority of herbal medicines are brewed 11 (35%). From the causality analysis using the Naranjo algorithm, it is known that the patients who used herbal medicines had 6 subjects in the possible category. Conclusion: The incidence of side effects of using herbal medicines in the Possible category. Keywords: herbal medicine, Naranjo, Possible.
Gambaran Kejadian Ikutan Pasca Imunisasi (KIPI) Setelah Melakukan Vaksinasi Covid-19 Pada Masyarakat Banjarmasin Selatan Darini Kurniawati; Iwan Yuwindry; Sariyasih Sariyasih
Jurnal Pelayanan Kefarmasian dan Sains Vol 2 No 2 (2022): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v2i2.187

Abstract

ABSTRACT Background : Covid-19 attacks the respiratory tract which first appeared in December 2019 in Wuhan City, Hubei Province, China. The World Health Organization (WHO) has declared it as a global pandemic since March 11, 2020. The COVID-19 vaccination program in Indonesia has started on January 13, 2021. Covid-19 vaccination can cause Post Immunization Adverse Events (AEFI) which can be characterized by mild to moderate symptoms. heavy. Objective : To find how to follow-up events after immunization (KIPI) in the people of southern Banjarmasin after the Covid-19 vaccination. Methods : This research is an observational quantitative research with descriptive research type, this research only describes an object of research, then the research data obtained in the form of numbers will be qualitatively obtained so that the results obtained can be described. This research was conducted using the naranjo algorithm which was distributed to the public and input via Google Form. Results : This study shows that 37 respondents with a percentage of men 51% and women 49% obtained a score of 4-8, namely "Most likely Terjasi ROM" with a total of 13 respondents, who used the Sinovac vaccine in 11 respondents and there were 2 moderna respondents. then with a score of 1-3, namely "Probability of ROM" with a total of 23 respondents who used the Sinovac vaccine. Then with a score of 0 which is "it is doubtful that ROM will occur" there are as many as 1 respondent with the Sinovac vaccine. Of the two vaccines, the Sinovac vaccine has an effectiveness of 56-65% while the Modena vaccine has an effectiveness of 94.1%. The common side effects of the Sinovac vaccine include injection pain, fever, fatigue, while the most common side effects of the moderna vaccine are fever, pain on injection, headache, and nausea. Conclusion : it can be concluded that Post-Immunization Adverse Events (AEFI) of respondents who vaccinated against covid-19 were 23 respondents in the Possible category, 13 respondents in the Probable category, and 1 respondent in the Doubtful category.
Pengaruh Tingkat Pengetahuan Mahasiswa Terhadap Efek Samping Vaksinasi Covid-19 di Universitas Sari Mulia: Pengaruh Tingkat Pengetahuan Mahasiswa Terhadap Efek Samping Vaksinasi Covid-19 di Universitas Sari Mulia Darini Kurniawati; Iwan Yuwindry
Jurnal Pelayanan Kefarmasian dan Sains Vol 3 No 2 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v3i2.281

Abstract

Background: In general, the side effects that arise after the vaccine vary. In general, mild and temporary and not always there and depending on the condition of the body. Effects such as fever and muscle aches or redness at the injection site are normal but still need to be monitored. The benefits of vaccines far outweigh the risks of getting sick from being infected if not vaccinated. If a Post-Immunization Follow-up Event (KIPI) occurs, it can be reported to the Health Facility where the vaccination is given, then it will be followed up by the focal point in each Health Service and reviewed by the KIPI Study and Management Committee in each region and nationally. To find out how the level of student understanding influences the side effects of the COVID-19 vaccination at Sari Mulia University, Banjarmasin. Objective: Knowing how to influence the level of student understanding of the side effects of COVID-19 vaccination at Sari Mulia University, Banjarmasin. Methods: This study used a descriptive observational cross-sectional design with purposive sampling with inclusion and exclusion criteria set by researchers at Sari Mulia University, Banjarmasin. Data analysis using Naranjo. Results: The results of the research on the incidence rate of drug side effects in the covid-19 vaccine in Sari Mulia University students obtained Probable results as many as 60 respondents, Possible as many as 23 respondents and Doubtful as many as 7 respondents. The results of the statistical analysis of the chi-square test using SPSS. Conclusion: Knowledge questionnaires that have an effect are place of residence, faculty and type of vaccine while age and gender do not affect knowledge. And for the Naranjo questionnaire, the factors that have an effect are the faculty and place of residence, while gender, age and type of vaccine have no effect. The alternative hypothesis (Ha) was accepted because it found that there was an effect on the level of student knowledge on the side effects of the Covid-19 vaccination at Sari Mulia University, Banjarmasin. Meanwhile, the null hypothesis (Ho) was rejected because there was no effect on the level of student knowledge on the side effects of the Covid-19 vaccination at Sari Mulia University, Banjarmasin. Keywords: Vaccines, Knowledge, Naranjo