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Journal : Jurnal Sains dan Kesehatan

Pola Penggunaan Obat Bahan Alam Sebagai Terapi Komplementer pada Pasien Hipertensi Di Puskesmas Swandari Paramita; Ronny Isnuwardana; Muhammad Khairul Nuryanto; Ruth Djalung; Dewi Guntar Rachmawatiningtyas; Prilandy Jayastri
Jurnal Sains dan Kesehatan Vol. 1 No. 7 (2017): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i7.56

Abstract

Hypertension is a major health problem throughout the world, including Indonesia. The use of traditional medicine as part of the treatment of hypertension is increasing in the last decade. This is due to several factors, especially traditional medicine is a cheaper alternative with fewer undesirable side effects. This study tried to look at the pattern of use of natural medicine as a complementary therapy in hypertensive patients at the health center. The study is a descriptive study conducted in Puskesmas Sempaja Samarinda in the period September 2016, interviewing 62 hypertension patients with the use of natural medicine. The results showed 70.9% of patients with hypertension in the health center also uses natural medicines. All patients using herbal medicine which in theory is proven to lower blood pressure. However, there is no natural medicines used include standardized herbal medicine or phytopharmacy. Only 15.2% of patients using herbal medicine in accordance with the criteria BPOM regulation on herbal medicine. For conclusions, this study shows the patients still need to be educated for the use of natural medicine in the management of hypertension.
Aktivitas Anti-Inflamasi In Vitro Ekstrak Etanol Daun Vernonia amygdalina DELILE Dengan Pengujian Stabilisasi Membran Muhammad Khairul Nuryanto; Swandari Paramita; Abdillah Iskandar; Sjarif Ismail; Andre Kusuma Ruslim
Jurnal Sains dan Kesehatan Vol. 1 No. 8 (2017): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i8.80

Abstract

Inflammation is a normal process in the human body as a response to injury from the healing process. Meanwhile, chronic inflammation will cause new health problems to patients. Anti-inflammatory agents generally used for those conditions, have several side effects to patients. The objective of this research was to find alternative anti-inflammatory agents, especially from natural sources. Vernonia amygdalina Delile knew locally as “Daun Bismillah” belong to family Apiaceae is one of those potential natural sources for alternative anti-inflammatory agents. This plant is known as traditional medicine and used as material in this research. The experimental method of in vitro anti-inflammatory measurement using membrane stabilization activity for ethanol extracts of V. amygdalina leaves. The results showed that significant differences of EC50 (p<0.05) were achieved between indomethacin as the positive control with V. amygdalina leaves extracts for concentration 1% and 10%. EC50 of leaves ethanol extract of V. amygdalina showed the potential anti-inflammatory activities. It could be concluded that V. amygdalina leaves ethanol extracts to have anti-inflammatory activities, which could be further developed as a new natural source of the anti-inflammatory agents.
Perbedaan Nilai Fraksi Ejeksi Ventrikel Kiri (LVEF) Pasien IMA-EST yang Menjalani Terapi Reperfusi dengan Fibrinolitik dan IKPP di RSUD Abdul Wahab Sjahranie Samarinda: Difference in Left Ventricular Ejection Fraction (LVEF) Value of AMI-EST Patients Underwent Reperfusion Therapy with Fibrinolytics and IKPP at Abdul Wahab Sjahranie Hospital, Samarinda Annisa Fitri Fadhilah; Djoen Herdianto; Muhammad Khairul Nuryanto
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.271

Abstract

Patients with Acute Myocardial Infarction with ST Segment Elevation (STEMI) should be given reperfusion therapy with fibrinolytic or PPCI (Primary Percutaneous Coronary Intervention) to prevent further myocardial damage. Currently PPCI is the main therapy choice for STEMI patients, but not all health facilities have these facilities. Thus, fibrinolytic may be the reperfusion therapy of choice in patients STEMI with chest pain onset ? 12 hours and without contraindications. STEMI can affect heart function, so the LVEF (Left Ventricular Ejection Fraction) value can be used to assess heart systolic function which can affect the prognosis of STEMI patients. The aim of this study was to identify the difference of LVEF values ??between STEMI patients undergoing reperfusion therapy with fibrinolytic and PPCI at Abdul Wahab Sajahranie Hospital, Samarinda. This study was an analytic observational study with a cross sectional design. The study population was all STEMI patients who undergoing reperfusion therapy with fibrinolytic and PPCI at Abdul Wahab Sjahranie Hospital, Samarinda for the period 2018-2019. Sampling was purposive sampling, with data sources derived from the patient's medical records. LVEF values ??were examined using transthoracic echocardiography, and Independent T-Test was used to analyze the difference of LVEF values ??between these groups. The result showed there was no significant difference in the LVEF value of STEMI patients undergoing reperfusion therapy with Fibrinolytics and PPCI (fibrinolytic 51.37 ± 12.254%, PPCI 56.47 ± 11.98%; p = 0.103 (p> 0.05)). Keywords: STEMI, Fibrinolytic, PPCI, LVEF