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All Journal Jurnal Kesehatan Jurnal Ilmiah Medicamento
Munifah Wahyuddin
Universitas Islam Negeri Alauddin Makassar
Health Professions Medicine & Pharmacology Nursing Public Health

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ANALISIS PENGELOLAAN OBAT SEBAGAI DASAR PENGENDALIAN SAFETY STOCK OBAT DI PUSKESMAS GANRA KABUPATEN SOPPENG Khaerani Khaerani; Haeria Haeria; Munifah Wahyuddin; Ika Yulianti
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.13643

Abstract

Drug management is an important aspect that include of planning, procurement, acceptance, storage, distribution, to the destruction of drugs. Drug management is a very important thing that needs to be considered, considering that with management that is not in accordance with the proper procedures, overlapping problems will occur. The Pharmacy Installation of the Soppeng District Health Office has carried out drug management but there are still a number of problems namely inadequate human resources, and inadequate facilities. This study aims to determine how the management of drugs in the Department of Health and Community Health Center Soppeng Ganra. This research is a descriptive analysis with a quantitative approach using observational methods. Data collection was carried out using the interview method through questionnaires. The results showed that the management of drugs in the Department of Health and Puskesmas Ganra, Soppeng Regency was not optimal because there were still many shortcomings such as controlling safety stock that had not used good calculations. The results of data percentage based on two different methods obtained 3.48% based on the proposed planning in 2018 and 96.51% using the planning method based on the calculation of safety stock.
EFEKTIVITAS SEDIAAN KRIM EKSTRAK UBI UNGU (Ipomoea batatas Poir) TERHADAP Staphylococcus aureus Munifah Wahyuddin; Munadiah Wahyuddin; Nurlia Naim; Nevyanti A.P
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.13644

Abstract

This study aims to determine the effectiveness of cream preparations from purple yam extract (Ipomoea batatas Poir) in inhibiting the growth of Staphylococcus aureus and to determine the concentration of purple sweet potato extract cream preparations (Ipomoea batatas Poir) which effectively inhibit Staphylococcus aureus. The method used in extraction was extracted using the percolation method. The resulting extract was then formulated in the form of cream preparations with varying concentrations of 10%, 15%, 20% and negative controls. Cream tests performed include organoleptic tests, pH, spreadability and type of cream. In testing the effectiveness of Staphylococcus aureus, using the wells method with Nutrient agar (NA) as a medium. Incubated for 24 hours then measuring the zone of inhibition produced in the medium. The results of research conducted for organoleptic (color and odor) tests with concentrations of 10%, 15%, and 20% are dark purple and have a characteristic odor of cream while negative controls are clear and odorless. In the pH test with concentrations of 10%, 15%, 20% ie 6.5 and negative control 6.4. In testing the spread of power with a concentration of 10%, 15% 20% and negative control respectively were 4.9cm, 5cm, 5.3cm and 4.5cm. In testing cream types with concentrations of 10%, 15%, 20% and negative controls are types of oil in water. For effectiveness testing, the most effective inhibition zone was obtained to inhibit Staphylococcus aureus with a concentration of 20% of 16.63 mm.
Studi Literatur Profil Farmakokinetik dan Penetrasi Antibiotik ke Jaringan Ulkus Diabetik Munifah Wahyuddin; Dwi Wahyuni Leboe; Khaerani Khaerani; Nurshalati Tahar; Alifia Putri Febriyanti; Nursyamsi Dhuha; Yuliani Yuliani
Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i2.4153

Abstract

A diabetic foot ulcer is a complication of diabetes that causes open sores that can develop into an infection. The selection of the right antibiotics is based on the pharmacokinetic profile of antibiotics that can show antibiotic activity as bactericidal or bacteriostatic, the main bacteria found in diabetic ulcer disease are gram-positive bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSa). This study aims to determine the antibiotics acting on diabetic ulcer tissue and the pharmacokinetic profile and penetration of antibiotics into diabetic ulcer tissue based on a literature study using the PICO (patient/population, intervention, comparison, and outcomes) method. The results of the analysis of 8 articles that met the inclusion criteria showed that the pharmacokinetic profile (PK) of several antibiotics obtained showed bactericidal activity in the treatment of diabetic ulcers including the antibiotics ceftolozane/tazobactam, tedizolid, cefepime, daptomycin, trimethoprim/sulfamethoxazole. Several antibiotics have shown activity as bacteriostatic in the treatment of diabetic ulcers, including linezolid antibiotics and vancomycin antibiotics.
Co-Authors Alifia Putri Febriyanti Dwi Wahyuni Leboe Haeria Haeria Ika Yulianti Khaerani Khaerani Munadiah Wahyuddin Nevyanti A.P Nurlia Naim Nurshalati Tahar Nursyamsi Dhuha Yuliani Yuliani