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All Journal Jurnal Ilmiah Medicamento JURNAL PENGABDIAN MASYARAKAT YAMASI
Dwi Wahyuni Leboe
Universitas Islam Negeri Alauddin Makassar
Health Professions Medicine & Pharmacology Public Health

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Studi Literatur Profil Farmakokinetik dan Penetrasi Antibiotik ke Jaringan Ulkus Diabetik Munifah Wahyuddin; Dwi Wahyuni Leboe; Khaerani Khaerani; Nurshalati Tahar; Alifia Putri Febriyanti; Nursyamsi Dhuha; Yuliani Yuliani
Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i2.4153

Abstract

A diabetic foot ulcer is a complication of diabetes that causes open sores that can develop into an infection. The selection of the right antibiotics is based on the pharmacokinetic profile of antibiotics that can show antibiotic activity as bactericidal or bacteriostatic, the main bacteria found in diabetic ulcer disease are gram-positive bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSa). This study aims to determine the antibiotics acting on diabetic ulcer tissue and the pharmacokinetic profile and penetration of antibiotics into diabetic ulcer tissue based on a literature study using the PICO (patient/population, intervention, comparison, and outcomes) method. The results of the analysis of 8 articles that met the inclusion criteria showed that the pharmacokinetic profile (PK) of several antibiotics obtained showed bactericidal activity in the treatment of diabetic ulcers including the antibiotics ceftolozane/tazobactam, tedizolid, cefepime, daptomycin, trimethoprim/sulfamethoxazole. Several antibiotics have shown activity as bacteriostatic in the treatment of diabetic ulcers, including linezolid antibiotics and vancomycin antibiotics.
PENYULUHAN PENGGUNAAN OBAT TRADISIONAL HABBATUSSAUDA UNTUK SISTEM IMUN DAN PENAMBAH DAYA INGAT BAGI SISWA MAN 2 KOTA MAKASSAR Nur Syamsi Dhuha; Nurshalati Tahar; Dwi Wahyuni Leboe; Munifah Wahyuddin; Khaerani Khaerani; Faridha Yenny Nonci
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 2 No. 1 (2023): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.495 KB) | DOI: 10.59060/jpmy.v2i1.280

Abstract

The use of black cumin as medicine or medicinal properties is in the seeds. The benefits of black cumin seeds are to treat various diseases such as strengthening the immune system, asthma, bronchitis, diabetes, increasing breast milk production, antihistamines or hypoallergenic, maintaining skin elasticity, antioxidants, antitumor, cancer, improving the digestive tract, antibacterial, lowering cholesterol and improve heart performance. In order to realize the degree of public health, it is necessary to carry out integrated and comprehensive health efforts in the form of individual health efforts and public health efforts. This community service aims to see how the level of knowledge of students at MAN 2 Makassar City about the use of Black Seed. Therefore, the results of this PKM show that it was synthesized by looking at the t count and t table for the two hypotheses. If (tcount) > ttable, then reject H0. Based on the analysis of the paired t test, if (tcount) is 4.86 and the ttable value for the two-way test is 2.11. Then, (t count) > ttable, then calculate H0 or in other words, that the means/average quiz results are significantly different from the means/average after being given counseling.
Co-Authors Alifia Putri Febriyanti Faridha Yenny Nonci Khaerani Khaerani Munifah Wahyuddin Nur Syamsi Dhuha Nurshalati Tahar Nursyamsi Dhuha Yuliani Yuliani