Khaerani Khaerani
Universitas Islam Negeri Alauddin Makassar

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ANALISIS PENGELOLAAN OBAT SEBAGAI DASAR PENGENDALIAN SAFETY STOCK OBAT DI PUSKESMAS GANRA KABUPATEN SOPPENG Khaerani Khaerani; Haeria Haeria; Munifah Wahyuddin; Ika Yulianti
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.13643

Abstract

Drug management is an important aspect that include of planning, procurement, acceptance, storage, distribution, to the destruction of drugs. Drug management is a very important thing that needs to be considered, considering that with management that is not in accordance with the proper procedures, overlapping problems will occur. The Pharmacy Installation of the Soppeng District Health Office has carried out drug management but there are still a number of problems namely inadequate human resources, and inadequate facilities. This study aims to determine how the management of drugs in the Department of Health and Community Health Center Soppeng Ganra. This research is a descriptive analysis with a quantitative approach using observational methods. Data collection was carried out using the interview method through questionnaires. The results showed that the management of drugs in the Department of Health and Puskesmas Ganra, Soppeng Regency was not optimal because there were still many shortcomings such as controlling safety stock that had not used good calculations. The results of data percentage based on two different methods obtained 3.48% based on the proposed planning in 2018 and 96.51% using the planning method based on the calculation of safety stock.
Studi Literatur Profil Farmakokinetik dan Penetrasi Antibiotik ke Jaringan Ulkus Diabetik Munifah Wahyuddin; Dwi Wahyuni Leboe; Khaerani Khaerani; Nurshalati Tahar; Alifia Putri Febriyanti; Nursyamsi Dhuha; Yuliani Yuliani
Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i2.4153

Abstract

A diabetic foot ulcer is a complication of diabetes that causes open sores that can develop into an infection. The selection of the right antibiotics is based on the pharmacokinetic profile of antibiotics that can show antibiotic activity as bactericidal or bacteriostatic, the main bacteria found in diabetic ulcer disease are gram-positive bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSa). This study aims to determine the antibiotics acting on diabetic ulcer tissue and the pharmacokinetic profile and penetration of antibiotics into diabetic ulcer tissue based on a literature study using the PICO (patient/population, intervention, comparison, and outcomes) method. The results of the analysis of 8 articles that met the inclusion criteria showed that the pharmacokinetic profile (PK) of several antibiotics obtained showed bactericidal activity in the treatment of diabetic ulcers including the antibiotics ceftolozane/tazobactam, tedizolid, cefepime, daptomycin, trimethoprim/sulfamethoxazole. Several antibiotics have shown activity as bacteriostatic in the treatment of diabetic ulcers, including linezolid antibiotics and vancomycin antibiotics.