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All Journal Jurnal Kesehatan Jurnal Fitofarmaka Indonesia PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal farmasi UIN Alauddin Makassar Jurnal Ilmiah Medicamento
Khaerani Khaerani
UIN Alauddin Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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ANALISIS PENGELOLAAN OBAT SEBAGAI DASAR PENGENDALIAN SAFETY STOCK OBAT DI PUSKESMAS GANRA KABUPATEN SOPPENG Khaerani Khaerani; Haeria Haeria; Munifah Wahyuddin; Ika Yulianti
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.13643

Abstract

Drug management is an important aspect that include of planning, procurement, acceptance, storage, distribution, to the destruction of drugs. Drug management is a very important thing that needs to be considered, considering that with management that is not in accordance with the proper procedures, overlapping problems will occur. The Pharmacy Installation of the Soppeng District Health Office has carried out drug management but there are still a number of problems namely inadequate human resources, and inadequate facilities. This study aims to determine how the management of drugs in the Department of Health and Community Health Center Soppeng Ganra. This research is a descriptive analysis with a quantitative approach using observational methods. Data collection was carried out using the interview method through questionnaires. The results showed that the management of drugs in the Department of Health and Puskesmas Ganra, Soppeng Regency was not optimal because there were still many shortcomings such as controlling safety stock that had not used good calculations. The results of data percentage based on two different methods obtained 3.48% based on the proposed planning in 2018 and 96.51% using the planning method based on the calculation of safety stock.
EVALUASI KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK RAWAT JALAN RSUP DR. WAHIDIN SUDIROHUSODO KOTA MAKASSAR Khaerani Khaerani; Gemy Nastity Handayany; Herlinda Sukamto
Jurnal Kesehatan THE 2nd ALAUDDIN PHARMACEUTICAL CONFERENCE AND EXPO (ALPHA-C) 2020
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.18208

Abstract

Patient satisfaction is an indicator of service quality, including in pharmaceutical services. This research about Evaluation of Patient Satisfaction (physical evidence, reliability, responsiveness, empathy, and guarantee) of Pharmaceutical Services at Dr. Wahidin Sudirohusodo’s Pharmacy Makassar period May-July 2017. The purpose of this study was to determine patient satisfaction with pharmacy services at the outpatient pharmacy Dr. Wahidin Sudirohusodo Makassar and To find out how the pharmaceutical service system is implemented by Pharmacists or pharmacist assistants at the Pharmacy. This research is a non-experimental descriptive research and is processed in quantitative analytic using Surveys approach. The population is all outpatients in RSUP Dr. Wahidin Sudirohusodo for the period May-July 2017 and 100 subjects were obtained. Primary data were obtained through research instruments using a questionnaire, then analyzed by univariate and bivariate analysis. The results showed that based on statistical analysis, 57% of respondents said they were satisfied with the service and the rest were less satisfied. Pharmacy Service System implemented by Pharmacists and Pharmacist Assistants is already good and carrying out their duties according to applicable SOPs only needs to be improved because the analysis results use the Chi square formula x2 count ≥ x2 tables then H0 is rejected meaning there is a significant difference between variable reliability, responsiveness, assurance, empathy and physical evidence.
EFEKTIVITAS INFUSA DAUN UBI JALAR (Ipomea batatas L) TERHADAP PENINGKATAN TROMBOSIT PADA MENCIT (Mus musculus) Khaerani Khaerani; Hasyim Barium; Faridah Yenny Nonci
Jurnal Farmasi UIN Alauddin Makassar Vol 2 No 1 (2014): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v2i1.2154

Abstract

Dengue fever is a disease that is still worrying for the people of Indonesia. Purple potato in general are well known in the community. Purple potato can be grown in all parts of Indonesia. Nutrient content of owned potatoes are very abundant, such as carbohydrates, proteins, vitamins, carotenoids  and  anthocyanin pigments  β-  needed  by the  body and  can  act  as  a  source  of antioxidants that can improve of platelets in thrombocytopenia condition. Research with an experimental design examined the effects of infusion of potato leaves in mice compared with various doses. And the results obtained in the form of an increase in platelet counts significantly in the provision of 200 g / 500 mL of achieving an increase in 203 / mm3 within 7 days.
PENGUJIAN AKTIVITAS INHIBITOR ENZIM TIROSINASE EKSTRAK N-HEKSAN DARI UMBI WORTEL (Daucus carrota L.) Syamsuri Syakri; Khaerani Khaerani; Hasrawati Hasrawati
Jurnal Farmasi UIN Alauddin Makassar Vol 8 No 2 (2020): Jurnal Farmasi Edisi November
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v8i2.14495

Abstract

Telah dilakukan penelitian tentang Pengujian aktivitas tirosinase ekstrak n-heksan DARI umbi wortel (Daucus carrora L.) mengandung senyawa flavonoid dan betakaroten golongan senyawa terpen yang merupakan senyawa yang dapat berpotensi untuk menghambat adanya tirosinae. Adanya inhibitor akan mengurangi dan menghentikan aktivitas tirosinase dalam memproduksi melanin yang nantinya akan mempengaruhi warna kulit. Tujuan penelitian ini untuk mengetahui seberapa besar aktivitas n-heksan umbi wortel (Daucus carrora L.) dalam menghibisi reaksi tirosin-tirosinase melalui nilai IC50 dengan konsentrasi 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, dan 50 ppm. Pada penelitian ini, pengujian aktivitas enzim tirosinase memberikan hasil akhir berupa DOPAchrome yang dapat menyerap energi sinar tampak yang dilakukan dengan menggunakan ELISA reader pada panjang gelombang 490 nm, dengan menggunakan asam kojat sebagai control positif. Hasil penelitian ini menunjukkan bahwa ekstrak n-heksan umbi wortel (Daucus carrora L.)memiliki aktivitas sebagai inhibitor tirosinasedengan rata-rata persen inhibitor berturut-turut yaitu 39,7 %, 40,2 %, 42,3 %, 42,3 %, 46,8 %, 47 %, 47,8 %, 48,5 %, dan 48,9 %. Ekstrak n-heksan umbi wortel memiliki nilai IC50 yaitu 50 µg/mL. Sedangkan asam kojat memiliki nilai IC50 sebesar 20 μg / mL. Hal ini menunjukkan bahwa ekstrak n-heksan umbi wortel memiliki aktivitas yang paling kuat sebagai inhibitor tirosinase.
Pengaruh Penambahan Fucoidan Pada Omeprazol Terhadap Perbaikan Gejala Dispepsia dan Kualitas Hidup Pada Pasien Dispepsia Fungsional Khaerani Khaerani; Suharjono Suharjono; Bambang Eko Wahyono
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 18 No. 01 Juli 2021
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i1.7568

Abstract

Dispepsia Fungsional merupakan salah satu gangguan fungsi pada gastrointestinal dan dapat berpengaruh terhadap kualitas hidup pasien. Fucoidan memiliki banyak efek farmakologi, salah satunya sebagai mukoprotektor dan bersifat sebagai anti ulcer pada gastrointestinal yang diduga dapat memperbaiki gejala dispepsia. Tujuan dari penelitian ini yaitu menganalisis efek penambahan fucoidan pada omeprazol terhadap perbaikan gejala dispepsia dan kualitas hidup pasien pada pasien dispepsia fungsional. Hasil yang diperoleh adanya perbaikan gejala dan kualitas hidup sebelum dan setelah menerima penambahan terapi fucoidan dengan nilai p < 0,05. Pada perbandingan perbaikan yang dilakukan pada kedua kelompok tidak terjadi perbaikan yang signifikan secara statistik dengan nilai p > 0,05 untuk beberapa domain kuesioner. Akan tetapi dalam perbaikan gejala klinik yang diobservasi terdapat perbaikan gejala dispepsia dan kualitas hidup yang lebih baik pada penambahan fucoidan.
Studi Literatur Profil Farmakokinetik dan Penetrasi Antibiotik ke Jaringan Ulkus Diabetik Munifah Wahyuddin; Dwi Wahyuni Leboe; Khaerani Khaerani; Nurshalati Tahar; Alifia Putri Febriyanti; Nursyamsi Dhuha; Yuliani Yuliani
Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i2.4153

Abstract

A diabetic foot ulcer is a complication of diabetes that causes open sores that can develop into an infection. The selection of the right antibiotics is based on the pharmacokinetic profile of antibiotics that can show antibiotic activity as bactericidal or bacteriostatic, the main bacteria found in diabetic ulcer disease are gram-positive bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSa). This study aims to determine the antibiotics acting on diabetic ulcer tissue and the pharmacokinetic profile and penetration of antibiotics into diabetic ulcer tissue based on a literature study using the PICO (patient/population, intervention, comparison, and outcomes) method. The results of the analysis of 8 articles that met the inclusion criteria showed that the pharmacokinetic profile (PK) of several antibiotics obtained showed bactericidal activity in the treatment of diabetic ulcers including the antibiotics ceftolozane/tazobactam, tedizolid, cefepime, daptomycin, trimethoprim/sulfamethoxazole. Several antibiotics have shown activity as bacteriostatic in the treatment of diabetic ulcers, including linezolid antibiotics and vancomycin antibiotics.
The Effect of Qur'an Reading in Jewawut Infusion (Setaria italica) on Changes in Cholesterol Levels: A Study in Vivo Haniah Haniah; Khaerani Khaerani; Munirah Munirah
Jurnal Fitofarmaka Indonesia Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i3.923

Abstract

Health is the main key in carrying out of daily activities. One of the health problems and can be dangerous if not treated properly is high cholesterol levels. One of the treatment efforts is to return to the Al-Qur'an. This study aims to combine the use of ruqyah water with the recitation of the verse al-Quran with jewawut herbs to reduce cholesterol levels. The method is laboratory experimental with pre-post test by measuring cholesterol levels before and after treatment in mice. There were 5 groups used, positive control, negative control, giving ruqyah water, giving jewawut infusion, giving ruqyah water to jewawut infusion. The results of this study showed a significant difference (p <0.05) in the provision of ruqyah water to jewawut infusion.
Co-Authors Alifia Putri Febriyanti Bambang Eko Wahyono Dwi Wahyuni Leboe Faridah Yenny Nonci Haeria Haeria Haniah Hasrawati Hasrawati Hasyim Barium Herlinda Sukamto Ika Yulianti Munirah Munirah Nurshalati Tahar Nursyamsi Dhuha Suharjono Syamsuri Syakri Wahyuddin, Munifah Yuliani Yuliani