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EVALUASI PENGGUNAAN OBAT ANTIDIABETIK ORAL PADA PASIEN DIABETES MELITUS TIPE 2 MENGGUNAKAN METODE ATC/DDD DAN DU 90% Nurshalati Tahar; Alifia Putri Febriyanti; Munifah Wahyuddin; Syahifah Auliyah Hasti
Jurnal Kesehatan THE 2nd ALAUDDIN PHARMACEUTICAL CONFERENCE AND EXPO (ALPHA-C) 2020
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.18380

Abstract

Diabetes mellitus is a chronic metabolic disease caused by the pancreas not producing enough insulin or not being able to use the required insulin effectively. Evaluate the use of oral antidiabetic drugs using ATC Diabetes mellitus is a chronic metabolic disease caused by the pancreas not producing enough insulin or not being able to use the required insulin effectively. Evaluate the use of oral antidiabetic drugs using ATC / DDD and DU 90% methods. Oral antidiabetic used in Makassar Hospita Hospital there are 3 types of metformin as many as 1020 units with a dose per unit that is 500 mg with a total use of 601000 mg 99.56%, more than 48 units with a perunit dose of 60 mg with a total dose of 2520 mg 0 , 41%, the last is 41 units of glimepiride with a perunit dose of 2 mg with a total use of 82 0.01%. Of the 3 types of oral antidiabetic, 3 usage patterns were obtained, namely 84% single metformin, 9% metformin + gliclazide combination pattern and 7% metformin + glimepirid combination. Included in the 90% DU segment or included in the list of incoming drugs is collected 90% of drug use after being sorted from the highest and highest percentage of drug use for compilation and low use is the use of metformin, using the correct use of drugs according to the choice, right dose, right delivery time, exact route and right information.
Studi Literatur Profil Farmakokinetik dan Penetrasi Antibiotik ke Jaringan Ulkus Diabetik Munifah Wahyuddin; Dwi Wahyuni Leboe; Khaerani Khaerani; Nurshalati Tahar; Alifia Putri Febriyanti; Nursyamsi Dhuha; Yuliani Yuliani
Jurnal Ilmiah Medicamento Vol 8 No 2 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i2.4153

Abstract

A diabetic foot ulcer is a complication of diabetes that causes open sores that can develop into an infection. The selection of the right antibiotics is based on the pharmacokinetic profile of antibiotics that can show antibiotic activity as bactericidal or bacteriostatic, the main bacteria found in diabetic ulcer disease are gram-positive bacteria such as Methicillin-Resistant Staphylococcus aureus (MRSa). This study aims to determine the antibiotics acting on diabetic ulcer tissue and the pharmacokinetic profile and penetration of antibiotics into diabetic ulcer tissue based on a literature study using the PICO (patient/population, intervention, comparison, and outcomes) method. The results of the analysis of 8 articles that met the inclusion criteria showed that the pharmacokinetic profile (PK) of several antibiotics obtained showed bactericidal activity in the treatment of diabetic ulcers including the antibiotics ceftolozane/tazobactam, tedizolid, cefepime, daptomycin, trimethoprim/sulfamethoxazole. Several antibiotics have shown activity as bacteriostatic in the treatment of diabetic ulcers, including linezolid antibiotics and vancomycin antibiotics.
EVALUASI TEPAT PENGGUNAAN OBAT LINI PERTAMA DAN LINI KEDUA ANTIHIPERTENSI PADA PASIEN PREEKLAMPSIA: A LITERATUR REVIEW Nurshalati Tahar; Egi Dwi Sakti Parenta; Alifia Putri Febriyanti; M Rusdi; Anieq Mumthi’ah Al Kautsar
Jurnal Midwifery Vol 3 No 2 (2021): AUGUST
Publisher : Prodi Kebidanan Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jmw.v3i2.24341

Abstract

Pendahuluan. Preeklampsia adalah suatu kelainan pada kehamilan termasuk hipertensi yang dapat menyebabkan kematian bayi. Preeklampsia merupakan suatu penyebab dari kematian perinatal kehamilan dan banyak terjadi di seluruh dunia. Tujuan penelitian ini adalah untuk mencegah dan mengobati hipertensi pada ibu, memperpanjang kehamilan dengan aman untuk janin yang lebih dewasa, dan meminimalkan paparan janin terhadap obat-obatan yang memberikan efek merugikan serta untuk mengetahui apakah penggunaan obat antihipertensi sudah sesuai dengan guidline pengobatan antihipertensi pada pasien preeklampsia. Metode pada penelitian ini adalah PICO (Population, Intervention, Comparation, Outcome). Hasil pengkajian menunjukkan bahwa obat Antihipertensi sering kali diresepkan terhadap pasien preeklampsia yang tidak sesuai dengan kebutuhan pasien. Hal ini dapat dijadikan acuan bagi dokter dan apoteker dalam meresepkan obat. Kesimpulan dari ke 20 jurnal yang telah di analisis dapat diketahui bahwa tepat penggunaan obat antihipertensi untuk pasien preeklampsia dapat dicapai dengan obat antihipertensi yang sesuai seperti golongan CCbs (Calsium-Channel Blockers) dan Beta Blockers sebagai obat pilihan pertama dan obat pilihan kedua untuk hipertensi pada ibu hamil.
Karakterisasi Komponen Kimia Hasil Fraksi Ekstrak Etanol Daun Sembukan (Paederia foetida L.) Dengan Menggunakan Spektroskopi Infra Red (IR) Nurshalati Tahar; Mukhriani Mukhriani; Fitra Insani
Jurnal Farmasi UIN Alauddin Makassar Vol 9 No 2 (2021): Jurnal Farmasi Edisi November
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v9i2.22110

Abstract

Penelitian mengenai karakterisasi komponen kimia hasil fraksi ekstrak etanol daun sembukan dengan menggunakan spektroskopi infra red. Penelitian ini bertujuan untuk mengetahui  gugus fungsi  bilangan gelombang yang terdapat dalam daun sembukan (Paederia foetida L.). metode yang digunakan pada penelitian ini adalah metode maserasi dengan menggunakan pelarut Etanol 96 %, Partisi dengan menggunakan metode partisi Cair-Cair, Identifikasi menggunakan KLT, Fraksinasi menggunakan metode kromatografi cair vakum (KCV), serta karakterisasi dengan menggunakan spektroskopi inrfa red (FTIR). Hasil yang didapatkan dari karakterisasi menggunakan spektroskopi infra red menunjukkan adanya gugus O-H, N-H, C=O, C=N, C=C, Ar-H, C-H, C=O, C=H, C≡C pada hasil fraksi.
PENYULUHAN PENGGUNAAN OBAT TRADISIONAL HABBATUSSAUDA UNTUK SISTEM IMUN DAN PENAMBAH DAYA INGAT BAGI SISWA MAN 2 KOTA MAKASSAR Nur Syamsi Dhuha; Nurshalati Tahar; Dwi Wahyuni Leboe; Munifah Wahyuddin; Khaerani Khaerani; Faridha Yenny Nonci
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 2 No. 1 (2023): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (57.495 KB) | DOI: 10.59060/jpmy.v2i1.280

Abstract

The use of black cumin as medicine or medicinal properties is in the seeds. The benefits of black cumin seeds are to treat various diseases such as strengthening the immune system, asthma, bronchitis, diabetes, increasing breast milk production, antihistamines or hypoallergenic, maintaining skin elasticity, antioxidants, antitumor, cancer, improving the digestive tract, antibacterial, lowering cholesterol and improve heart performance. In order to realize the degree of public health, it is necessary to carry out integrated and comprehensive health efforts in the form of individual health efforts and public health efforts. This community service aims to see how the level of knowledge of students at MAN 2 Makassar City about the use of Black Seed. Therefore, the results of this PKM show that it was synthesized by looking at the t count and t table for the two hypotheses. If (tcount) > ttable, then reject H0. Based on the analysis of the paired t test, if (tcount) is 4.86 and the ttable value for the two-way test is 2.11. Then, (t count) > ttable, then calculate H0 or in other words, that the means/average quiz results are significantly different from the means/average after being given counseling.