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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Unri Conference Series: Community Engagement TAMKIN Jurnal Pengabdian Masyarakat
Nurfi Pratiwi
Universitas Riau
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health Social Sciences

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Pengaruh Infeksi Laten Toksoplasmosis Terhadap Lama Rawatan Skizofrenia Episode Pertama Rina Amtarina; Andriza Andriza; Nurfi Pratiwi; Sarah Udayana
Jurnal Ilmu Kedokteran Vol 15, No 1 (2021): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v15i1.2021.21-25

Abstract

Toxoplasma metabolism effect can rise the dopamine production which aggravate the simptoms of schizophrenia. Some of the research reports that patients which diagnosed with schizophrenia with positive IgG Toxoplasma need longer duration of treatment and may relapse. This study was conducted by cross sectional method on 51 patients with first episode schizophrenia, including acute and temporary psychotic disorder, in Tampan Mental Hospital – Pekanbaru. IgG anti-toxoplasma were detected on the patients at the first treatment in 2019, and then the length period of treatment and the recurrence frequency were monitored in the first year of the course of the disease. From the chi square test result, we can conclude that there’s no effect of IgG Toxoplasma on the duration of treatment on the first episode schizophrenia patients as well as the recurrence frequency which monitored in the first year course of the disease (p>0.05). There’s no effect of IgG Toxoplasma on the duration of treatment on the first episode schizophrenia patients as well as the recurrence frequency.
Pemberdayaan masyarakat melalui pengolahan sampah anorganik menjadi barang dekoratif bernilai ekonomis Huriatul Masdar; Muhammad Yulis Hamidy; Fifia Chandra; RM Riadi; Yulia Irvani Dewi; Nurfi Pratiwi
Unri Conference Series: Community Engagement Vol 2 (2020): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.2.222-227

Abstract

Garbage is the leftover product from every human daily activity that is thrown away which, if not managed properly, can cause environmental and health problems. Waste bank is a form community participation in waste management. Air Putih Sub-dsitrict already has a waste bank that is actively operating. However its activities are still limited to collect inorganic waste from customers and sell it to collectors. In order to increase the value of inorganic waste collected in the waste bank, a training to decorate used items using decoupage technique was conducted. Waste bank managers and Empowerment Family Welfare (PKK) members were participated in this training. In addition, a training how to use social media as a marketing media were performed. The results showed that the target community's skills had been achieved in processing inorganic waste into decorative items with higher economic value. Meanwhile, the sustainability of production and the economic impact resulting from these trainings still require further evaluation.
Vitamin D enhances migration but decreases gene expression of vascular endothelial growth factor and tumor necrosis factor-α in Wharton’s jelly mesenchymal stem cells Vitriyanna Mutiara Yuhendri; Nurfi Pratiwi; Ariza Julia Paulina; Ismawati Ismawati; Nicko Pisceski Kusika Saputra; Arfianti Arfianti
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 1 (2025): Advances in Biomarkers, Therapeutics, and Probiotics: Recent Updates in Medical L
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i1.6698

Abstract

Mesenchymal stem cells (MSCs) have gained significant interest for their potential application in repairing damaged tissues through immunomodulatory functions. Vitamin D has been shown to regulate both the innate and adaptive immune systems. Active forms of Vitamin D, such as 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) are known to influence the action of mesenchymal stem cells (MSCs) in several mechanisms, such as stimulating their proliferation and osteogenic differentiation, as well as tissue regeneration. This study aimed to investigate the effects of vitamin D supplementation on the biological properties and expression of cytokines and growth factor genes in MSCs isolated from the human umbilical cord (UC). MSCs were isolated from Wharton’s jelly (WJ-MSC) of UC, cultured, and supplemented with various concentrations of vitamin D3. The Cell Counting Kit-8 (CCK-8) assay was used to measure cell viability, and a scratch wound healing assay was conducted to evaluate the migration capacity of MSCs. The mRNA expression levels of vascular endothelial growth factor (VEGF), tumor necrosis factor (TNF)-α, and interleukin (IL)-6 were quantified using reverse transcription-polymerase chain reaction (RT-PCR). This study showed that supplementation with 50 nM of vitamin D3 for 48 h significantly increased the viability and migratory capacity of MSCs. Furthermore, vitamin D supplementation significantly decreased the mRNA levels of TNF-α and VEGF but did not affect IL-6 gene expression compared to the control group. These findings suggest that vitamin D supplementation can enhance the biological characteristics and modulate the expression of key immunomodulatory factors in MSCs, potentially improving the effectiveness of MSC-based therapies.
Progressive Muscle Relaxation (PMR) Training to Improve Mental Health of COVID-19 Survivors at Tanjung Medang Health Center NURFI PRATIWI; RAHMAT AZHARI KEMAL; ARFIANTI ARFIANTI; RINA AMTARINA
Tamkin Jurnal Pemberdayaan Tazkia Vol. 4 No. 2 (2026): TAMKIN: Jurnal Pengabdian Masyarakat
Publisher : Tazkia Islamic University College

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30993/tamkin.v4i2.919

Abstract

Despite being declared cured, some of the patients recovering from COVID-19 experience sequelae that last weeks or months. This situation can increase the risk of mental health, one of which is anxiety disorders. One therapy in overcoming anxiety problems is doing progressive muscle relaxation exercises. Progressive muscle relaxation training is an active technique that involves participants actively contracting muscles to create relaxation by progressively relaxing them. In August of 2022, a series of activities were implemented for individuals who had survived COVID-19 in the North Rupat District of the Bengkalis Regency. Participants included patients who had been previously diagnosed with COVID-19 of various ages and were currently experiencing sequelae of COVID-19 such as anxiety. Participants were given counseling about mental health after COVID-19. After that, the survivors were demonstrated and invited to participate in practicing progressive muscle relaxation (PMR) exercises. The DASS score before activity indicated 20% of the survivors who attended experienced anxiety. After the counseling and training, there was an increase in knowledge regarding the average post-test score of 92 compared to the average pre-test score of 65. This PMR knowledge is expected to be practiced sustainably by the community to improve mental health. Keywords: Anxiety; COVID-19; Mental health; Progressive muscle relaxation training; Survivors
Co-Authors Andriza Andriza Arfianti Arfianti Ariza Julia Paulina Fifia Chandra Huriatul Masdar Ismawati ismawati Muhammad Yulis Hamidy Nicko Pisceski Kusika Saputra Rahmat Azhari Kemal Rina Amtarina Rina Amtarina RM Riadi Sarah Udayana Vitriyanna Mutiara Yuhendri Yulia Irvani Dewi