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All Journal Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Jurnal Pengabdian UntukMu NegeRI Jurnal Kedokteran Anatomica (Anatomica Medical Journal) INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Prosiding Konferensi Nasional PKM-CSR CANANG: Jurnal Pengabdian Masyarakat
Ariza Julia Paulina
Universitas Riau
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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PENGARUH LAMA PEMBERIAN DIET ATEROGENIK TERHADAP INDEKS ATEROGENIK SERUM Rattus novergicus STRAIN WISTAR JANTAN Ariza Julia Paulina; Enikarmila Asni; Mardhiah Gaffar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Atherosclerosis is defined as a chronic inflammation which is marked by the accumulation of cholesterol and ester cholesterol in the sub endotelial vascular tissue. The ratio of LDL/HDL (atherogenic index) is the main parameter in atherosclerosis and CHD incidence. The purpose of this research is to know the effect of long giving atherogenic diet against serum atherogenic index in male Wistar rat. This study was an experimental research with the post test-only control group design, by using male rats (Rattus novergicus) of 2-3 month with the average weight range of 160-240 gr. The rats are then divided into 4 group which are: control group given with standard diet, the 5 weeks atherogenic diet group, the 8 weeks atherogenic group, and the 12 weeks atherogenic group, in which group consist of 6 rats. The atherogenic diet (2% cholesterol, 5% goat’s fat, and 0,2% cholic acid) is given ad libitum as much as 20 gr/ea/day. The result are then analyzed with the one way ANOVA method, showing that there’s a adequate difference (p=0,000). As for the Post Hoc Test (p=0,000), the result show is that the atherogenic diet does increase the atherogenic index of the rats blood serum. And as for the Spearman test (0,969), it show is a significant positive correlation between the atherogenic index and the given duration of the atherogenic diet. In this research we can conclude that the longer given atherogenic duration, the higher the atherogenic index will become on male Wistar rats (Rattus novergicus).Keywords: Atherosclerosis, atherogenic diet, atherogenic index, LDL/HDL ratio, rats (Rattus novergicus)
Peningkatan Kapasitas Kader Posyandu Desa Tambang Dalam Deteksi Stunting Pada Anak Arfianti Arfianti; Nurhasanah Nurhasanah; Suri Dwi Lesmana; Yuliati Yuliati; Erika Erika; Ariza Julia Paulina; Dedi Afandi
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 3 (2020): Peran Perguruan Tinggi dan Dunia Usaha Dalam Pemberdayaan Masyarakat Untuk Menyongsong
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.856 KB) | DOI: 10.37695/pkmcsr.v3i0.792

Abstract

Stunting merupakan kondisi malnutrisi kronis pada anak yang ditandai dengan tinggi badan anak berada di bawah 2 standar deviasi dibawah grafik pertumbuhan anak. Stunting menjadi masalah kesehatan yang serius terutama di negara-negara berkembang, termasuk di Indonesia. Kampar merupakan salah satu wilayah prioritas penanganan stunting di Provinsi Riau dengan 10 lokus stunting yang telah diidentifikasi. Desa Tambang Kecamatan Tambang merupakan desa di Kabupaten Kampar dengan prevalensi stunting cukup tinggi yaitu memiliki 42 balita. Tujuan dari kegiatan pengabdian ini adalah meningkatkan pengetahuan dan keterampilan kader Desa Tambang dalam melakukan penilaian status gizi anak balita. Pengabdian dilakukan pada bulan Juli 2020 di Kantor Camat Tambang. Metode pelatihan meliputi ceramah, tanya jawab, studi kasus dan praktek langsung pengukuran tinggi dan berat badan anak balita. Topik pelatihan meliputi stunting dan strategi pencegahan stunting di desa, penilaian status gizi anak balita serta kebutuhan gizi ibu hamil dan anak balita. Pelatihan diikuti oleh 25 kader posyandu yang ada di Desa Tambang. Hasil evaluasi kegiatan menggunakan kuesioner pre-test dan post-test menunjukkan terdapat peningkatan pengetahuan kader posyandu tentang stunting dan strategi pencegahannya.
Antibodi Sars-Cov-2 Pasca Vaksinasi Pada Penyintas Covid-19 Dita Kartika Sari; Rahmat Azhari Kemal; Ariza Julia Paulina
ANATOMICA MEDICAL JOURNAL | AMJ Vol 5, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/amj.v5i3.12589

Abstract

Salah satu kendala program vaksinasi dalam penanganan pandemi Corona Virus Disease 19 (COVID-19) adalah stok vaksin yang terbatas. Beberapa studi pada vaksin mRNA menunjukkan bahwa penyintas COVID-19 menunjukkan respon yang lebih cepat dalam membentuk antibodi. Penelitian ini bertujuan memberikan gambaran awal mengenai respon imun penyintas COVID-19 setelah pemberian vaksin CoronaVac. Metode: 14 sampel dari penyintas COVID-19 yang divaksinasi menggunakan CoronaVac diambil untuk melihat total antibodi terhadap Receptor Binding Domain (RBD) protein spike SARS- CoV-2 yang diperiksa dari serum pada sebelum vaksinasi, 14 hari setelah dosis pertama, dan 14 hari setelah dosis kedua. Hasil: Didapatkan 6 orang penyintas mempunyai antibodi anti RBD (seropositif) sedangkan 8 orang lainnya tidak (seronegatif). Rerata durasi PCR positif menunjukkan individu seronegatif memiliki waktu yang lebih singkat (3,3 ± 1,7 hari, p<0.001) dibandingkan kelompok seropositif Kesimpulan: Kelompok penyintas seropositif mengalami peningkatan antibodi yang signifikan setelah pemberian vaksin dosis pertama (GMT 648.6, 95% CI 360.7 – 1,166.0 U/mL). Titer ini signifikan lebih tinggi jika dibandingkan dengan kelompok seronegatif bahkan setelah pemberian vaksin dosis kedua (GMT 49.1, 95% CI 14.0 – 172.7 U/mL). Temuan awal ini harus direplikasi dalam sampel yang lebih besar untuk mengidentifikasi prioritas vaksinasi diantara individu yang sebelumnya terinfeksi.Kata kunci: Antibodi anti-RBD, Penyitas COVID-19, Vaksinasi
Penyuluhan Anemia Dan Pemeriksaan Hemoglobin Pada Ibu Hamil Di Puskesmas Sungai Sembilan Fatmawati; Ariza Julia Paulina; Fridayenti
Jurnal Pengabdian UntukMu NegeRI Vol 7 No 1 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v7i1.4288

Abstract

Maternal Mortality Rate (MMR) is an indicator to assess the degree of a nation, especially women. MMR according to the results of the 2012 Indonesian Demographic and Health Survey in Indonesia was 359 per 100,000 live births. The most common causes of maternal death in the city of Dumai are ante partum hemorrhage and preeclampsia in 3 cases each. The purpose of this service activity is to increase knowledge and understanding of anemia in pregnant women and to find out the status of anemia in pregnant women at the Sungai Sembilan Health Center, Sungai Sembilan District, Dumai Regency. In addition to counseling activities, a pre-test and post-test were carried out using 10 multiple-choice questions to assess the knowledge of the community, totaling 30 people. Overall, more than 50% of participants already have a good level of knowledge about anemia in pregnancy. There were 33% of participants who had a hemoglobin level <11 which means they had mild anemia. By conducting counseling about anemia and hemoglobin examination, it is hoped that it can increase the knowledge of the community at the Sungai Sembilan Health Center, Sungai Sembilan District, Dumai Regency.
Pemberdayaan Masyarakat Dalam Pengendalian Tekanan Darah Pada Nelayan Teluk Rhu, Rupat Utara Zulkarnaini, Zulkarnaini; Suyanto, Suyanto; Thamrin, Thamrin; Paulina, Ariza Julia; Rosmayani, Rosmayani; Fitriana, Riza
CANANG: Jurnal Pengabdian Masyarakat Vol 4, No 2 (2024)
Publisher : PELANTAR PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52364/canang.v4i2.49

Abstract

Hypertension is one of the main health problems at risk of causing cardiovascular diseases, such as heart attack and stroke, which requires special attention in coastal areas, including Teluk Rhu Village, North Rupat Sub-district, Bengkalis Regency. Based on an initial survey, the incidence of hypertension in this village is quite high, especially among fishermen who have an irregular lifestyle and limited knowledge about the risks of hypertension. In order to overcome this problem, Community Service activities (PKM) were carried out on May 20, 2024 with the aim of increasing community knowledge and awareness about hypertension through counseling, health checks, and distribution of educational materials. This activity also involves students as facilitators and brings health services closer to people living in remote areas.The evaluation results showed that this program succeeded in increasing community knowledge about hypertension and its prevention measures. Of the 30 participants who took part in the blood pressure check, 10 of them were diagnosed with hypertension and given recommendations for treatment and regular check-ups. In addition, this activity also introduced technology in the form of educational media such as posters and videos to deepen the community's understanding of the symptoms and management of hypertension. Although the program has been running well, there is still a need to improve health facilities and early detection to expand the scope of education and treatment, especially for high-risk communities. With the establishment of a hypertension club and improved health services, it is hoped that the prevalence of hypertension can be reduced and the quality of life of the people of Teluk Rhu Village improved
Penyuluhan Anemia Dan Pemeriksaan Hemoglobin Pada Anak-Anak di Panti Asuhan Baiturrahmah, Kampar Paulina, Ariza Julia; Fatmawati, Fatmawati; Fridayenti; Chandra Wijaya; Meimi Laila; Nada Idzdihari Adesti; Erva Roudhotul Jannah; Sisilia Indah Cahyani
Jurnal Pengabdian UntukMu NegeRI Vol. 9 No. 1 (2025): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v9i1.8889

Abstract

Iron deficiency anemia is the most common nutritional deficiency in the world, 30% of the population. From the results of a household health survey in Indonesia, the incidence of iron deficiency anemia reached 48.1% in children under five and 47.3% in school-aged children. Iron deficiency can cause interference with the immune response, making it susceptible to infection, gastrointestinal disorders, impaired cognitive function, growth and development, and changes in behavior. Purpose: this service activity is to increase knowledge about iron deficiency anemia and determine the anemia status of orphaned children at the Baiturrahmah Rimbo Panjang Orphanage, Tambang District, Kampar Regency. Method: counseling was carried out about Iron deficiency anemia by doctor, to assess the level of knowledge given in the pre test and post test. In addition, blood hemoglobin levels arechecked to see anemia status. Result: Service activities in the form of counseling have succeeded in increasing the knowledge of children about anemia. Hemoglobin levels were checked and it was found that 73.5% of orphanage children had hemoglobin levels <11 g/dL, which means they were anemic. So further treatment is needed to reduce the incidence of anemia in orphanage children. Keywords: Iron deficiency anemia, hemoglobin, children, Kampar
Penapisan Dan Pencegahan Hiperkolesterolemia di Desa Mukti Sari, Kecamatan Tapung, Kampar Ariza Julia Paulina; Fatmawati; Chandra Wijaya; Meimi Laila; Tiara Yulia Rahmi; Fadli Maggribi
Jurnal Pengabdian UntukMu NegeRI Vol. 9 No. 1 (2025): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v9i1.8903

Abstract

Cholesterol sufferers in Indonesia are quite high, reaching 28%, that 7.9% of them die due to hypercholesterolemia. Hypercholesterolemia can lead to the risk of atherosclerosis, coronary heart disease (CHD), pancreatitis, diabetes mellitus, liver disease, thyroid disorders and kidney disease. In 2020, CHD was the main cause of death, around 36% of all deaths. Risk factors for hypercholesterolemia include genetics, consumption of high-fat foods, lack of exercise and smoking habits. The aim of this activity is to improve the knowledge of the people of Mukti Sari Village, Tapung District, Kampar Regency, Riau Province about hypercholesterolemia and detect hypercholesterolemia so that it can be managed further. The activity stages consist of: participants were given questions before and after education activities about hypercholesterolemia. Check blood cholesterol levels using the Family Dr. cholesterol checker. Service activities in the form of counseling succeeded in increasing the knowledge of the people of Mukti Sari Village, Tapung District, Kampar Regency about hypercholesterolemia. There are 3% of the people of Mukti Sari Village who experience hypercholesterolemia. Keywords: Coronary Heart Disease (CHD), Hypercholesterolemia, Kampar, Mukti Sari Village
Vitamin D enhances migration but decreases gene expression of vascular endothelial growth factor and tumor necrosis factor-α in Wharton’s jelly mesenchymal stem cells Yuhendri, Vitriyanna Mutiara; Pratiwi, Nurfi; Paulina, Ariza Julia; Ismawati, Ismawati; Saputra, Nicko Pisceski Kusika; Arfianti, Arfianti
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 1 (2025): Advances in biomarkers, therapeutics, and probiotics: Recent updates in medical l
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i1.6698

Abstract

Mesenchymal stem cells (MSCs) have gained significant interest for their potential application in repairing damaged tissues through immunomodulatory functions. Vitamin D has been shown to regulate both the innate and adaptive immune systems. Active forms of Vitamin D, such as 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) are known to influence the action of mesenchymal stem cells (MSCs) in several mechanisms, such as stimulating their proliferation and osteogenic differentiation, as well as tissue regeneration. This study aimed to investigate the effects of vitamin D supplementation on the biological properties and expression of cytokines and growth factor genes in MSCs isolated from the human umbilical cord (UC). MSCs were isolated from Wharton’s jelly (WJ-MSC) of UC, cultured, and supplemented with various concentrations of vitamin D3. The Cell Counting Kit-8 (CCK-8) assay was used to measure cell viability, and a scratch wound healing assay was conducted to evaluate the migration capacity of MSCs. The mRNA expression levels of vascular endothelial growth factor (VEGF), tumor necrosis factor (TNF)-α, and interleukin (IL)-6 were quantified using reverse transcription-polymerase chain reaction (RT-PCR). This study showed that supplementation with 50 nM of vitamin D3 for 48 h significantly increased the viability and migratory capacity of MSCs. Furthermore, vitamin D supplementation significantly decreased the mRNA levels of TNF-α and VEGF but did not affect IL-6 gene expression compared to the control group. These findings suggest that vitamin D supplementation can enhance the biological characteristics and modulate the expression of key immunomodulatory factors in MSCs, potentially improving the effectiveness of MSC-based therapies.
Co-Authors AA Sudharmawan, AA Arfianti Arfianti Chandra Wijaya Chandra Wijaya Dedi Afandi Dita Kartika Sari Enikarmila Asni Erika Erika Erva Roudhotul Jannah Fadli Maggribi Fatmawati Fatmawati Fatmawati Fatmawati, Fatmawati Fitriana, Riza Fridayenti Fridayenti Ismawati Ismawati Mardhiah Gaffar Meimi Laila Nada Idzdihari Adesti Nurfi Pratiwi, Nurfi Rahmat Azhari Kemal Rosmayani, Rosmayani S.Pd. M Kes I Ketut Sudiana . Saputra, Nicko Pisceski Kusika Sisilia Indah Cahyani Suri Dwi Lesmana Suyanto Suyanto Thamrin Thamrin Tiara Yulia Rahmi Yuhendri, Vitriyanna Mutiara Yuliati Yuliati