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SARS-CoV-2 infection and male fertility problems Ika Inda Bani; Zulkarnain Zulkarnain; Gholib Gholib; Dedy Syahrizal; Fauzul Husna; Winda Yulia; Mulkan Azhari
Trends in Infection and Global Health Vol 2, No 2 (2022): December 2022
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v2i2.29426

Abstract

In 2019, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), has killed more than 6.6 millions of people around the world as of end of 2022. The long-term impact of COVID-19 is persisted, including its impact on male reproduction. SARS-CoV-2 enters into host cells using the angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) receptors. Both of these receptors are expressed more in men, and therefore men are more susceptible to SARS-CoV-2. COVID-19 potentially cause infertility by damaging testicular tissues and interfering with the process of spermatogenesis. A decrease in serum levels of testosterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) as well as a decrease in sperm quality in men with COVID-19 compared to healthy men of the same age has been reported in several studies. Utilizing existing research data, this study aims to explore in detail of how SARS-CoV-2 tends to affect male fertility.
The Impact of Photoaging on Skin: A Systematic Review Analysis Muhammad Shanan Asyi; Dedy Syahrizal; Nirwana Lazuardi Sary; Fauzul Husna
Journal of Social Research Vol. 3 No. 1 (2023): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v3i1.1708

Abstract

Aging of the skin is a complex biological process. The process of skin aging can be divided into two categories namely intrinsic and extrinsic aging. Intrinsic skin aging or natural aging is caused by changes in skin elasticity that occur with age. This type of aging cannot be prevented. While extrinsic skin aging is caused by environmental factors such as exposure to solar radiation (photoaging). In this study, the type of research approach used is a type of qualitative research through a literature review. The type of data used is the type of secondary data. Secondary data is a type of data obtained from certain parties or media indirectly, meaning that certain parties become intermediaries where they obtain and record these data beforehand. The aging process of the skin is influenced by intrinsic and extrinsic factors. The extrinsic factor that most influences the aging process of the skin is chronic sun exposure which is called photoaging. Sunlight contains 96% UVA and has the most significant biological effect compared to UVB and UVC. Several factors that affect photodamaging are skin type, pigmentation, and acclimatization. Skin changes that occur in photoaging include the presence of vesicles in the epidermis, reduced Langerhans cells, and enlarged and pale epidermal cells; in the dermis, there is an elastic mass; pigment changes in the form of dotted (irregular pigmentation) and hyperpigmentation.