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Efek Formalin terhadap Jumlah Sel Spermatogenik Dhalila, Hasyifa; Zulfitri, Zulfitri; Sofia, Sofia
Kes Mas: Jurnal Fakultas Kesehatan Masyarakat Vol 11, No 1 (2017): Kes Mas: Jurnal Fakultas Kesehatan Masyarakat
Publisher : Universitas Ahmad Dahlan

Background: The high number of formalin abuse as a food additive and formaldehyde exposure in daily life can caused the adverse effect, one of that is infertility. The purpose of this research was to determine the effect of formaldehyde on the number of spermatogenic cells, which illustrated disruption of spermatogenesis. Methods: This research was an experimental research with post-test only with control group design. The subject of this research were 24 white rats (Rattus norvegicus) Wistar strain. Test of Hiypothesis used software of Statistical Package for the Social Sciences (SPSS) with One-way Anova test with significance 0.05. Results: The average number of spermatogonia cells (P0:291.50; P1:237.50; P2:185.83; P3:156.67), primary spermatocytes cells (P0:296,17; P1:261,33; P2:203,83; P3:171,33), and spermatid cells (P0:722.67; P1:663.67; P2:385.00; P3:287.83) decreased than control, and the results of One-way Anova test was p=0.00. Conclusion: There was a significant difference in the number of spermatogenic cells of the control group with the formalin treatment group.

Impacts of Education's Intervention on Solid Medical Waste Management in Improving Knowledge, Attitude, and Behavior of Medical Health Workers Sofia Sofia; Wiku ST Yogasmara; Hafni Andayani; Ratna Idayati
Britain International of Exact Sciences (BIoEx) Journal Vol 3 No 1 (2021): Britain International of Exact Sciences Journal, January
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v3i1.375

The purpose of this study was to determine the effect of providing education on increasing knowledge, attitudes, and behavior of medical officers in solid medical waste management at the Regional General Hospital dr. Zainoel Abidin Banda Aceh, Indonesia. The research design used was a quasi experiment with the Wilcoxon comparison test. The research sample was the medical officer of dr. Zainoel Abidin Banda Aceh as many as 94 people who were divided into treatment and control groups. Knowledge, attitude, and the behavior of medical personnel was measured by interview using a questionnaire. The results showed that there was an effect of educational interventions on increasing the knowledge, attitudes, and behavior of medical personnel in the management of medical solid waste in the treatment and control groups (p <0.05). The results of the Wilcoxon test between the treatment groups on knowledge, attitudes, and behavior before and after the educational intervention showed a significant difference (p = 0.000), whereas in the control group between before and after the educational intervention did not show a difference with the p-value of knowledge (p = 0.102); attitude and behavior (p = 0.157). In the control group, the level of knowledge, attitudes and behavior tends to remain at a sufficient level. The conclusion of this study shows that educational interventions can provide an increase in the knowledge, attitudes and behavior of medical personnel in implementing solid medical waste management at dr. Zainoel Abidin Banda Aceh.

BASIC MEDICAL SCIENCES AND PROBLEM-BASED LEARNING: PITFALLS AND POSSIBLE IMPROVEMENT FROM THE PERSPECTIVE OF TEACHERS AND STUDENTS Teuku Renaldi; Said Usman; Maimun Syukri; Sofia Sofia; Dedy Syahrizal
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 9, No 3 (2020): November
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.57165

Background: Basic medical sciences are essential foundation for the constructive learning of clinical sciences. Faculty of Medicine, Universitas Syiah Kuala is currently implementing Problem-based learning (PBL) for basic medical sciences. Studies have been conducted in many places with inconsistently different results that it is impossible to draw theoretical and practical conclusions regarding the implementation of PBL for basic medical sciences. This study aimed to evaluate the implementation of PBL for basic medical sciences at Faculty of Medicine, Universitas Syiah Kuala from the perspectives of pre-clinical teachers, clinical teachers and medical students.Methods: This is a qualitative study with a phenomenological approach. Respondents were pre-clinical teachers, clinical teachers and medical students. Data collection were carried out by using focused-group discussion (FGD). Data analysis was carried out qualitatively by using thematic analysis.Results: This study identified three themes: (1) integrated thematic blocks are not adequate for the learning of basic medical sciences, (2) inadequacy of basic medical sciences practice activities, and (3) possible improvements through curriculum revision.Conclusion: The implementation of PBL in the form of integrated blocks for basic medical sciences is not adequately constructive to prepare students to learn clinical sciences. Hybrid curriculum which incorporates conventional methods for basic medical sciences and PBL for clinical sciences is recommended to improve students’ constructive learning. Further studies on hybrid curriculum is needed to evaluate its effect of basic medical sciences. Keywords: Basic medical sciences, Problem-based learning (PBL), practical session, hybrid curriculum, constructive learning, self-directed learning.

RELATIONSHIP OF RISK FACTORS FOR STUNTING IN BADUTA AGES 6-24 MONTHS IN BAITUSSALAM DISTRICT ACEH BESAR DISTRICT Sofia Sofia; Irma Agustina; Nora Sovira; Mulya Safri; Iflan Nouval
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 5 No 2 (2021): Medical Technology and Public Health Journal September 2021
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v5i2.3002

The problem of stunting in Aceh Besar exceeds the standard set of WHO, which is 38.7% caused by many risk factors. This study aims to determine the risk factors of stunting in children aged 6-24 months in Baitussalam, Aceh Besar. The type of this research is observational analytic with a cross-sectional method that involves 189 children under two years old. Data were collected by filling out questionnaires, maternal and child health books, and measuring body length. The results showed that children who are stunted were 24.3% and those who were not stunted were 75.7%. There were stunting children with a history of non-exclusive breastfeeding (93.5%), pre-term gestational age (82.6%), a history of low birth weight (10.9%), mothers with junior high school education levels (60.9%), fathers with junior high school education level (45.7%) and low family income (68.8%). Statistical test analysis found that the risk factors of stunting have a relationship with history of exclusive breastfeeding (p-value = 0.00), gestational age (p-value = 0.00), history of low birth weight (p-value = 0.022), mother’s education level (p-value = 0.00), father's education level (p-value 0.002) and family income (p-value = 0.00). This study concluded that risk factors which include the history of exclusive breastfeeding, gestational age, history of LBW, education level of mother and father, and family income have a relationship with the incidence of stunting in Baitussalam District, Aceh Besar District.

Earthquake and Tsunami Emergency Preparedness of Visually Disabled People Mutia Fatin; Sofia Sofia; Rina Suryani Oktari
International Journal of Disaster Management Vol 3, No 1 (2020): June
Publisher : TDMRC, Universitas Syiah Kuala

This study aims to assess the level of preparedness of visually disabled people in terms of the emergency response plan for earthquake and tsunami. This study uses analytical methods, cross-sectional design, and questionnaires as data collection tools. The sample of this study was 54 visually disabled people who were living in Banda Aceh. The analysis revealed that the level of preparedness of the emergency response plan, the majority of visually disabled people has a low level of preparedness to plan an emergency response (63%), especially the total blindness group (46.3%). The Mann-Whitney test results showed that there was a statistically significant relationship between the visual impairment group and total blindness group on the preparedness of the emergency response plan (p = 0.016). Hence, this study suggests some recommendations, including a disaster preparedness program that is sensitive to people with disabilities, increasing the participation of people with disabilities in DRR education, and increasing the accessibility of people with disabilities to DRR teaching/learning materials.

Hubungan Pengetahuan dan Sikap Terhadap Perilaku Berisiko Miopia pada Siswa SMAN 10 Fajar Harapan Banda Aceh M. Alfian Zainal; Saiful Basri; Sofia Sofia
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 5 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Miopia atau rabun jauh adalah kondisi sumbu bola mata anteroposterior yang terlalu panjang atau kekuatan pembiasan media refraksi yang terlalu kuat sehingga menyebabkan kekaburan ketika melihat objek jauh. Berdasarkan data WHO pada tahun 2010, persentase kejadian miopia di dunia adalah 27% dan diperkirakan pada tahun 2050 persentase ini akan meningkat sampai 49,8%. Oleh karena itu, memahami status pengetahuan dan sikap terhadap perilaku berisiko miopia menjadi penting agar dapat mencegah peningkatan kejadian miopia. Tujuan penelitian ini adalah mengetahui hubungan pengetahuan dan sikap terhadap perilaku berisiko miopia pada siswa SMAN 10 Fajar harapan Banda Aceh. Penelitian ini merupakan penelitian analitik observasional dengan rancangan cross sectional. Sampel penelitian ini adalah siswa SMAN 10 Fajar Harapan Banda Aceh sebanyak 246 responden. Pengambilan sampel menggunakan teknik simple random sampling. Pengumpulan data dilakukan pada tanggal 26 November hingga 1 Desember 2021 dengan menyebarkan kuesioner secara tidak langsung. Analisis statistik yang digunakan pada penelitian ini adalah uji Chi-square. Hasil penelitian menunjukkan bahwa 120 responden (48,8%) memiliki pengetahuan yang kurang, 110 responden (44,7%) memiliki sikap yang kurang dan 141 responden (57,3%) berperilaku berisiko miopia. Berdasarkan hasil analisis menunjukkan tidak ada hubungan antara pengetahuan tentang miopia terhadap perilaku berisiko miopia dengan p-value 0,080 (p > 0,05), namun terdapat hubungan antara sikap terhadap miopia dengan perilaku berisiko miopia dengan p-value 0,000 (p ? 0,05). Kesimpulannya, pengetahuan tentang miopia tidak berpengaruh terhadap perilaku berisiko miopia namun sikap terhadap miopia berpengaruh terhadap perilaku berisiko miopia.

Uji selektivitas fraksi Rf < 0,5 ekstrak MeOH biji putat air (Barringtonia racemosa) terhadap ikan mujair (Oreochromis mossambicus) Musri Musman; Sofia S; Adli W Perdana
Depik Vol 1, No 2 (2012): August 2012
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Abstract. The objective of the present study was to evaluate the selectivity of the Rf 0.5 fraction of MeOH extract of putat air kernels (Barringtonia racemosa) on golden snail (Pomacea canaliculata) and tilapia (Oreochromis mossambicus). The research was conducted on November 2011 to February 2012 at Chemical Laboratory of Teacher Training and Education Facultyand Marine Chemical Laboratory of Coordinatorate of Marine and Fisheries of Syiah Kuala University. Thin-layer chromatography was used as the separation technique towards component compounds in the extract samples. The research was used five levels concentration of Rf 0.5 fraction of MeOH solution (20 ppm, 40 ppm, 60 ppm, 80 ppm, 100 ppm) with three repetitions. Mortality rates of golden snails and tilapia were detected when they were exposure to Rf 0.5 fraction of MeOH extract of B. racemosa kernels. The data were analyzed by Probit, and selectivity value (S) was calculated by Feng and Wang formula. The results revealed that Rf 0.5 fraction of MeOH extract of putat air kernels was selective to golden apple snails.Key words. Thin-layer chromatography, mortality, Probit, and moluscida

Selektivitas fraksi Rf < 0,5 ekstrak etil asetat (EtOAc) biji putat air (Barringtonia racemosa)terhadap keong mas (Pomacea canaliculata) dan ikan lele lokal (Clarias batrachus) Musri Musman; Sofia F; Viqqi Kurnianda
Depik Vol 1, No 2 (2012): August 2012
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Abstract. Research to determine the selectivity of fraction Rf 0.5 of ethyl acetate extract (EtOAc) of putat air kernel (Barringtonia racemosa) on golden apple snail(Pomacea canaliculata) and local catfish (Clarias batrachus) was conducted in February 2012 at the Laboratory of Chemistry of Teacher Training and Education Faculty and Laboratory of Marine Chemistry of Coordinatorate of Marine and Fisheries of Syiah Kuala University. Thin-layer chromatography was used to separate components in the extract samples, and testing of biological activity based on the procedures recommended by FAO. Golden apple snail and local catfish mortality data were analyzed using Probit program, and value of selectivity (S) was processed according to the Wang and Feng’s formula.The values of LC50 of the fraction Rf 0.5 were 29.26 ppm for P. canaliculata and 44.47 ppm for C. batracus. The selectivity value for the tested organisms was 1.51. This study revealed that the tested extract has bioactive property as molluscicide of P. canaliculata.Key words. Biological activity, thin-layer chromatography, mortality, bioactive property, molluscicide, LC50.

Uji selektivitas fraksi Rf < 0,5 ekstrak MeOH biji putat air (Barringtonia racemosa) terhadap ikan mujair (Oreochromis mossambicus) Musri Musman; Sofia S; Adli W Perdana
Depik Vol 1, No 2 (2012): August 2012
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13170/depik.1.2.50

Abstract. The objective of the present study was to evaluate the selectivity of the Rf 0.5 fraction of MeOH extract of putat air kernels (Barringtonia racemosa) on golden snail (Pomacea canaliculata) and tilapia (Oreochromis mossambicus). The research was conducted on November 2011 to February 2012 at Chemical Laboratory of Teacher Training and Education Facultyand Marine Chemical Laboratory of Coordinatorate of Marine and Fisheries of Syiah Kuala University. Thin-layer chromatography was used as the separation technique towards component compounds in the extract samples. The research was used five levels concentration of Rf 0.5 fraction of MeOH solution (20 ppm, 40 ppm, 60 ppm, 80 ppm, 100 ppm) with three repetitions. Mortality rates of golden snails and tilapia were detected when they were exposure to Rf 0.5 fraction of MeOH extract of B. racemosa kernels. The data were analyzed by Probit, and selectivity value (S) was calculated by Feng and Wang formula. The results revealed that Rf 0.5 fraction of MeOH extract of putat air kernels was selective to golden apple snails.Key words. Thin-layer chromatography, mortality, Probit, and moluscida

Selektivitas fraksi Rf < 0,5 ekstrak etil asetat (EtOAc) biji putat air (Barringtonia racemosa)terhadap keong mas (Pomacea canaliculata) dan ikan lele lokal (Clarias batrachus) Musri Musman; Sofia F; Viqqi Kurnianda
Depik Vol 1, No 2 (2012): August 2012
Publisher : Faculty of Marine and Fisheries, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13170/depik.1.2.35

Abstract. Research to determine the selectivity of fraction Rf 0.5 of ethyl acetate extract (EtOAc) of putat air kernel (Barringtonia racemosa) on golden apple snail(Pomacea canaliculata) and local catfish (Clarias batrachus) was conducted in February 2012 at the Laboratory of Chemistry of Teacher Training and Education Faculty and Laboratory of Marine Chemistry of Coordinatorate of Marine and Fisheries of Syiah Kuala University. Thin-layer chromatography was used to separate components in the extract samples, and testing of biological activity based on the procedures recommended by FAO. Golden apple snail and local catfish mortality data were analyzed using Probit program, and value of selectivity (S) was processed according to the Wang and Feng’s formula.The values of LC50 of the fraction Rf 0.5 were 29.26 ppm for P. canaliculata and 44.47 ppm for C. batracus. The selectivity value for the tested organisms was 1.51. This study revealed that the tested extract has bioactive property as molluscicide of P. canaliculata.Key words. Biological activity, thin-layer chromatography, mortality, bioactive property, molluscicide, LC50.

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