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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Darussalam Nutrition Journal Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) AcTion: Aceh Nutrition Journal Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Jurnal Ners MAHESA : Malahayati Health Student Journal Indonesian Journal of Global Health Research
Syahrial, Syahrial
Universitas Andalas
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary Other

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Peran Zat Gizi dan Senyawa Bioaktif Daun Kelor (Moringa oleifera) dalam Pengendalian Diabetes Melitus: Literature Review Ainul Mardiah; Syahrial Syahrial; Jeallyza Muthia Azra
MAHESA : Malahayati Health Student Journal Vol 6, No 9 (2026): Volume 6 Nomor 9 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i9.26641

Abstract

ABSTRACT Diabetes mellitus is a metabolic disease that requires effective blood glucose control. Moringa oleifera leaves contain various nutrients and bioactive compounds that have potential benefits in diabetes management.This literature review aimed to examine the role of nutrients and bioactive compounds in Moringa oleifera leaves for diabetes mellitus management based on studies published between 2021 and 2026. A literature review was conducted by searching articles from Google Scholar, PubMed, ScienceDirect, and SpringerLink databases. A total of 10 articles that met the inclusion criteria were analyzed. Moringa oleifera leaves were found to reduce blood glucose levels, improve insulin sensitivity, enhance lipid profiles, and decrease oxidative stress. These effects are attributed to the presence of flavonoids, polyphenols, quercetin, chlorogenic acid, dietary fiber, vitamin C, and β-carotene, which contribute to glucose metabolism regulation through various biological mechanisms. Moringa oleifera leaves have strong potential as a functional food for diabetes mellitus management due to their nutrient and bioactive compound content, which supports blood glucose regulation. Keywords: Moringa Oleifera, Diabetes Mellitus, Functional Food, Bioactive Compounds. ABSTRAK Diabetes melitus merupakan penyakit metabolik yang memerlukan pengendalian kadar glukosa darah. Daun kelor (Moringa oleifera) mengandung berbagai zat gizi dan senyawa bioaktif yang berpotensi membantu pengelolaan diabetes. Mengkaji peran zat gizi dan senyawa bioaktif daun kelor dalam pengendalian diabetes melitus berdasarkan penelitian tahun 2021–2026.Literatur review dilakukan melalui pencarian artikel pada Google Scholar, PubMed, ScienceDirect, dan SpringerLink. Sebanyak 10 artikel yang memenuhi kriteria inklusi dianalisis. Daun kelor terbukti mampu menurunkan kadar glukosa darah, meningkatkan sensitivitas insulin, memperbaiki profil lipid, dan mengurangi stres oksidatif. Efek tersebut dipengaruhi oleh kandungan flavonoid, polifenol, quercetin, asam klorogenat, serat pangan, vitamin C, dan β-karoten yang bekerja melalui berbagai mekanisme pengendalian metabolisme glukosa. Daun kelor berpotensi sebagai pangan fungsional dalam pengelolaan diabetes melitus karena kandungan zat gizi dan senyawa bioaktifnya yang mendukung pengendalian glukosa darah. Kata Kunci: Moringa Oleifera, Diabetes Melitus, Pangan Fungsional, Senyawa Bioaktif.
Co-Authors Ainul Mardiah Ayu Putri Babby Ika Pratiwi Deni Elnovriza Faiz Nur Hanum Febby Wardatul Jannah Frima Elda Handayani, Marni Helmizar INDAH WULANDARI Iza Ayu Saufani Jeallyza Muthia Azra Mirnawati Mirnawati Nindrea, Ricvan Dana Resmiati Resmiati Rizka Adelia Lubis Tazkia Putri Kagami