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All Journal Jurnal Fisika Unand Jurnal Riset Kimia IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Zarah Akta Kimia Indonesia Media Ilmu Kesehatan Molekul: Jurnal Ilmiah Kimia Current Research on Biosciences and Biotechnology Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Hydrogen: Jurnal Kependidikan Kimia JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Katalisator Molekul: Jurnal Ilmiah Kimia
Suryati
Departemen Kimia, Fakultas Matematika Dan Ilmu Pengatahuan Alam, Universitas Andalas, Padang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Bioactivity of Red Leaf Extract of Pucuk Merah Plant (Syzygium myrtifolium Walp.) Suryati; Santoni, Adlis; Arifin, Bustanul; Aisya, Nurul; Frisky, Sintia; Aisyah, Siti
Jurnal Riset Kimia Vol. 16 No. 1 (2025): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v16i1.760

Abstract

Syzygium myrtifolium Walp. is an ornamental plant traditionally used as an herbal medicine. Ethanol extract of Syzygium myrtifolium Walp. has been reported to have activities as an antioxidant, anticancer, and antimicrobial. In this study, Syzygium myrtifolium Walp is extracted. Leaves were carried out using a multistage maceration method using methanol, ethyl acetate, and hexane solvents. Antioxidant, antimicrobial, and toxicity tests were performed, and secondary metabolite compounds, total flavonoid content, and total phenolic content were identified on red leaf extract. Total phenolic content was tested using the Folin-Ciocalteau reagent, total flavonoids with the AlCl3 reagent, antioxidants with the DPPH method, antimicrobial using the disc diffusion method, and toxicity tested using the BSLT method. The result showed that Syzygium myrtifolium Walp. Red leaf extract contained a secondary metabolite of triterpenoids, steroids, phenolics, flavonoids, alkaloids, and coumarins. The ethyl acetate and methanol extract's total phenolic and flavonoid content were 311.0520 and 420.360 mg GAE/g extract and 211.788 and 105.360 mg QE/g extract. Antioxidant activity of ethyl acetate and methanol showed that the extracts were highly antioxidant with IC50 of 19.606 and 12.0656 mg/L. The antimicrobial activity showed that the hexane extract was resistant to the bacteria Staphylococcus aureus and Propionibacterium acnes and the fungus Candida albicans. However, no inhibition zones were produced for Pseudomonas aerigunosa and Escherichia coli bacteria. The toxicity test showed that the hexane and ethyl acetate extract had strong toxic properties with LC50 of 56.65 and 16.79 mg/L, and the methanol extract was toxic with LC50 of 224.2846 mg/L.
Antibacterial Activity of Triterpenoid from The Leaves of Tahi Ayam (Lantana camara Linn) Kartika MZ; Suryati Suryati; Mai Efdi
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 8, No 3 (2023): October 2023
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v8.i3.110

Abstract

Tahi Ayam (Lantana camara Linn) is known as the herbal plant to cure several diseases and has been used in folk medicine. The result of this study indicates that the isolated compound and the ethyl acetate fraction are components having antibacterial activity. The isolated compound from the ethyl acetate fraction from the leaves of the Lantana camara Linn plant is 9-hydroxy-Lantadene A. The compound includes the triterpenoid compound group, the molecular formula is C35H52O6, and another name is 22-angeloiloxy-9-hydroxy-3-oxo-olean-12-en-28-oat. The antibacterial activity of this compound was determined by looking at the inhibition zone of the test bacteria, namely Staphylococcus aureus as gram-positive and Escherichia coli as gram-negative. The treatment has been using the disc diffusion method and using amoxicillin as a control positive. The result of the antibacterial activity test revealed that both 9-hydroxy-Lantadene A and the ethyl acetate fraction exhibited antibacterial activity. Becouse there are inhibition zones around the discs at concentrations of 10 μg/disk and 5 μg/disk.
Co-Authors Aditya Perdana Adlis Santoni Afrizal Afrizal Aisya, Nurul Asri Amelia Bustanul Arifin Bustanul Arifin Bustanul Arifin Bustanul Arifin Dachriyanus Deswati Deswati Elida Mardiah Emriadi - Enda Desriansyah Aziz Enda Desriansyah Aziz Farid Al-Huzaini Fatma Sri Wahyuni Frisky, Sintia Gustia Elizar Hilda Sartika Indah Putri Lestari Kartika MZ Kartika MZ Kartika Kusumasari, Viantika Leidina Zein M Lutfi Firdaus M. Fadly Maghfirah, Sucy Mai Efdi Matlal Fajri Alif Miftahul Melsya Salsabilla Mudinillah, Adam Nadila Arrahim Norman Ferdinal Novesar Jamarun Nurdin, Hazli Nurhamidah Nurhamidah Olly Norita Tetra Rahmi Vika Ulia Rini Ramadani Safni Safni Salim, Emil Sanaq Elfira Putri Sanusi Ibrahim Sari Wahyuni Shafinna Hana Fadhia Silfani Mairanti Siti Aisyah Siti Nur Hidayah, Siti Nur Syukri Arief Thaharah Alifa Aziz Yenuuar Vira Anggita Gusniardi Wini Sukrila Yayan Rabbani Kurniawan Yeni Stiadi Yetria Rilda Yosie Andriani Yulizar Yusuf Yuni Malasari Zilfa Zilfa