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All Journal Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Denta: Jurnal Kedokteran Gigi Odonto dental journal
Adisty Restu Poetri
Department Of Periodontics, Faculty Of Dentistry, Sultan Agung Islamic University
Dentistry Health Professions Medicine & Pharmacology Public Health

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EKSTRAK DAUN SALAM DALAM MENINGKATKAN EKSPRESI FIBROBLAST GROWTH FACTOR PADA ULKUS TRAUMATIK RONGGA MULUT Amrina Rosada; Rochman Mujayanto; Adisty Restu Poetri
Odonto : Dental Journal Vol 7, No 2 (2020): December 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.866 KB) | DOI: 10.30659/odj.7.2.90-96

Abstract

Background: Traumatic ulcers are lesions of the oral mucosa caused by mechanical, chemical, and temperature trauma. Traumatic ulcer treatment aims to reduce inflammation, accelerate the healing process, and reduce pain. Bay leaf has anti-inflammatory pharmacological activities. This study aims to determine the effect of bay leaf extract on the expression of fibroblast growth factor in traumatic ulcer oral mucosa in Wistar rats.Method: This is an experimental research with a post-test only control group design, consisting of four groups with 20 sample of male Wistar rats. All animals were injured using a hot burnisher attached to the labial mucosa for 1 second. The gel was applied twice daily until the 3rd and 5th day after the ulcer has formed. Rat mucosal tissues were analyzed by immunohistochemical staining for FGF expressions. Statistical analysis using SPSS Mann-Whitney test.Result: The results showed the mean of cells expressing FGF in the bay gel extract group on the 3rd and 5th days were 8.4 ± 0.8, and 13.6 ± 0.5. Mann Whitney test results showed P<0.05 there is a significant differential expression of FGF traumatic ulcer oral mucosa of experimental animals on days 3 and 5 compared control group.Conclusion: Bay leaf extract increased FGF expression on days 3 and 5
The Effect of Adding Propolis to Formula Milk on The Streptococcus Sobrinus Inhibition Zone (In Vitro) Welly Anggarani; Adisty Restu Poetri; Dinda Nabila Alfani
Denta Journal Kedokteran Gigi Vol 18 No 1 (2024): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v18i1.5

Abstract

  Background: Caries is one of the dental and oral health problems that are often suffered by children. One of the main causes is the habit of children consuming formula milk as it contains sucrose. Streptococcus sobrinus is an oral pathogenic bacteria that has a role in the initial process of dental caries. One of the natural ingredients that function as anti-caries is propolis. Objective: Therefore, this study aims to determine the effect of adding propolis to formula milk on the inhibition zone of Streptococcus sobrinus bacteria. Methods: This type of research is a Laboratory Experiment with a Post-Test control Group Design. It consists of 4 groups, namely the formula milk group without propolis as a negative control, the formula milk treatment group with propolis concentrations of 5%, 10%, and 20% carried out with 7 replications of each group. The sample is a pure isolate of Streptococcus sobrinus bacteria. Results: The results showed the average inhibition zone was the formula milk group without propolis was 0.00±0.00 mm, the formula milk group with propolis concentration of 5% was 12.87±1.18 mm, the formula milk group with propolis concentration of 10% was 16.65±1.51 mm, and the formula milk group with propolis concentration of 20% was 24.87±0.39 mm. Conclusion: It means the addition of propolis to formula milk has been proven to be effective in inhibiting the growth of Streptococcus sobrinus bacteria.
Co-Authors Adhiatarika Rismadanti Adhiatarika Rismadianti Adinda Nur Atiqah Amrina Rosada Anggun Amanda Saveria Anggun Feranisa Dinda Nabila Alfani Dinda Vinca Rosa Hamizul Fuad Helmi Fathurrahman, Helmi Kwartarini Murdiastuti Niam, Moh Husnun Niluh Ringga Woroprobosari Niluh Ringga Woroprobosari Rochman Mujayanto Rosa Pratiwi, Rosa Sudibyo sudibyo Welly Anggarani