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THE DIFFERENCE OF EFFECTIVITY BETWEEN MANGOSTEEN PEEL EXTRACT AND METRONIDAZOLE ON FIBROBLAST PROLIFERATION Adinda Nur Atiqah; Adisty Restu Poetri; Moh Husnun Niam
ODONTO : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.1.80-85

Abstract

Background: The disease of the oral cavity is quite common in the society is periodontitis. The main cause of this condition is a certain bacterial infection found in dental plaque. In general, metronidazole gel will be given as additional therapy to treat bacterial colonization. Mangosteen peel extract gel contains xanthones and flavonoids which are known to be antibacterial and anti-inflammatory. This research aims to specify the differences in the effectiveness of anti-inflammatory between mangosteen peel extract and metronidazole gel on fibroblast proliferation.Method: This is a laboratory experimental design using post-test only design consisted of 50% mangosteen peel extract gel group, 75% mangosteen peel extract gel group, 25% metronidazole gel group and metronidazole plus gel group. This research used male Wistar rats induced periodontitis by ligation for 7 days as samples.Results: The results reveal that there was a differences in effectiveness between the 4 groups against the proliferation of fibroblast were analyzed using One Way ANOVA with a significance of 0.000 (p<0.05).Conclusion: It can be concluded that there was differences in the effectiveness of mangosteen peel extract gel and metronidazole gel as anti-inflammatory on proliferation of fibroblast in periodontitis healing process.
THE DIFFERENCE OF EFFECTIVITY BETWEEN MANGOSTEEN PEEL EXTRACT AND METRONIDAZOLE ON FIBROBLAST PROLIFERATION Adinda Nur Atiqah; Adisty Restu Poetri; Moh Husnun Niam
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.959 KB) | DOI: 10.30659/odj.8.1.80-85

Abstract

Background: The disease of the oral cavity is quite common in the society is periodontitis. The main cause of this condition is a certain bacterial infection found in dental plaque. In general, metronidazole gel will be given as additional therapy to treat bacterial colonization. Mangosteen peel extract gel contains xanthones and flavonoids which are known to be antibacterial and anti-inflammatory. This research aims to specify the differences in the effectiveness of anti-inflammatory between mangosteen peel extract and metronidazole gel on fibroblast proliferation.Method: This is a laboratory experimental design using post-test only design consisted of 50% mangosteen peel extract gel group, 75% mangosteen peel extract gel group, 25% metronidazole gel group and metronidazole plus gel group. This research used male Wistar rats induced periodontitis by ligation for 7 days as samples.Results: The results reveal that there was a differences in effectiveness between the 4 groups against the proliferation of fibroblast were analyzed using One Way ANOVA with a significance of 0.000 (p<0.05).Conclusion: It can be concluded that there was differences in the effectiveness of mangosteen peel extract gel and metronidazole gel as anti-inflammatory on proliferation of fibroblast in periodontitis healing process.
Empowerment of Zero Waste Maritime Village Based on Creative Economy in Wirittasi Village, Kusan Hilir, Tanah Bumbu Syarifah Khusnul Khotimah; Nasruddin; Hanida Aulia Santi; Anastasya Rosyida An-Nafi; Siti Aulia; Akhmad Nabil Arifin; Hardiansyah; Muhammad Fakhruz Zaini; Muhammad Syarif Hidayatullah; Amirul Mukminin; Asse Padly; Ainol Amin; Amelia Rosanti; Firman Maulana; Muhammad Sulaiman Jazuli; Adinda Nur Atiqah
Asian Journal of Community Services Vol. 2 No. 11 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajcs.v2i11.6758

Abstract

The empowerment of Zero Waste Maritime Village Caring for the Marine Environment Based on Creative Economy was organized by the PPK Ormawa HMG Team, Lambung Mangkurat University, through socialization and education methods, training, and mentoring to the people of Wirittasi Village. With this program, the community can realize the potential of waste in Wirittasi Village. The activity results show that the district already has knowledge and skills in managing waste in Wirittasi Village through waste sorting activities and the 3R Movement. If continued, this program will improve the economic opinion of the community through waste management activities by the community. To maintain the program's sustainability, it is necessary to implement further programs, and the participation of village and local governments as facilitators for this community empowerment activity is needed.