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All Journal Jurnal Pengabdian Pada Masyarakat Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Mandala Pharmacon Indonesia Jurnal Ilmu Kesehatan Abdi Geomedisains Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat Panacea Pharmacon: Jurnal Farmasi Indonesia Strada Journal of Pharmacy Journal of Pharmascience
Julianti, Tri Budi
Farmasi, Universitas Muhammadiyah Kalimantan Timur
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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The Effects of a Low-Carbohydrate Diet on Glycemic Control and Weight in Patients with Type 2 Diabetes Mellitus: Literature Review Tri Budi Julianti; Tania Putri; Dewi Lutfania Syahrani; Javier Ammar; Siti Khadijah; Rizki Nur Azmi
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.241

Abstract

Type 2 diabetes mellitus (T2DM) is an increasing global health problem characterized by chronic hyperglycemia due to insulin resistance and/or insulin secretion deficiency. T2DM management often focuses on glycemic control and weight loss through lifestyle interventions, including diet. Low-carbohydrate diets (LCDs) have been one of the most debated and researched dietary interventions, with claims of improving glycemic control and facilitating weight loss. This literature review aims to synthesize the current scientific evidence on the effect of DRK on glycemic control (HbA1c, fasting glucose) and weight in T2DM patients. A systematic review method will be used to identify, evaluate and summarize relevant studies from electronic databases. The review will present key findings from studies, discuss underlying mechanisms, and identify potential benefits, risks, and limitations of DRK. This literature review is expected to provide a more comprehensive understanding for clinical practitioners, patients, and researchers in considering DRK as a T2DM management strategy.
Formulasi dan Evaluasi Fisik Sediaan Emulgel Ekstrak Etanol Daun Kitolod (Isotoma longiflora (L.) C.Presl) dengan Variasi Konsentrasi Carbopol-940 sebagai Gelling Agent Syarifah Nur Oktarina Putri; Tri Budi Julianti
Jurnal Mandala Pharmacon Indonesia Vol. 12 No. 1 (2026): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v12i1.1174

Abstract

Tanaman kitolod mengandung senyawa flavonoid yang memiliki aktivitas antioksidan. Emulgel salah satu jenis produk semipadat yang merupakan kombinasi sistem emulsi dan gel, sehingga memiliki keuntungan dalam kenyamanan penggunaan dan daya sebar pada sediaan topikal. Ekstrak daun kitolod diformulasikan dalam sediaan topikal berpotensi mengatasi permasalahan kulit dalam menangkal radikal bebas. Daun kitolod berpotensi sebagai antioksidan karena mengandung senyawa flavonoid. Salah satu bahan pembentuk emulgel yaitu carbopol-940 sebagai Gelling agent yang bermanfaat untuk membentuk viskositas dan memperbaiki sifat fisik serta reologi sediaan. Tujuan penelitian ini untuk mengevaluasi pengaruh variasi konsentrasi carbopol-940 sebagai Gelling agent pada karakteristik fisik dan stabilitas fisik terhadap sediaan emulgel. Penelitian ini merupakan penelitian eksperimental. Emulgel dibuat dengan variasi konsentrasi carbopol-940 sebesar 0,5%, 1%, 1,5%, dan 2%, dengan masing-masing formula dilakukan pengujian 3x replikasi. Emulgel dilakukan evaluasi fisik meliputi uji organoleptis, homogenitas, daya lekat, daya sebar, pH, viskositas, sineresis, tipe emulsi, stabilitas fisik, serta uji hedonik. Data dianalisis menggunakan uji normalitas, dilanjutkan dengan One Way Anova untuk data berdistribusi normal (p > 0,05) atau uji Kruskal-Wallis untuk data tidak normal. Uji hedonik dengan hasil signifikan (p < 0,05) dilanjutkan menggunakan uji Mann-Whitney. Hasil menunjukkan variasi konsentrasi carbopol-940 sebagai Gelling agent mempengaruhi karakteristik fisik dan stabilitas fisik terhadap sediaan emulgel. Formula 1 dengan konsentrasi carbopol-940 1% menunjukkan hasil terbaik berdasarkan parameter viskositas, daya sebar, daya lekat, pH, stabilitas fisik selama penyimpanan, serta tingkat kesukaan panelis pada uji hedonik terutama pada parameter tekstur.
Water Hyacinth Extract in Herbal Medicine Development: Literature Review Zelvisya Sayutri; Rahmawati Safitri; Raodhatul Jannah; Rahma Azkiah; Tri Budi Julianti
Strada Journal of Pharmacy Vol. 7 No. 2 (2025): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v7i2.242

Abstract

Indonesia is a country with an extraordinary wealth of flora, one of which is water hyacinth (Eichhornia crassipes) which has been known as an invasive aquatic weed. Recent studies have shown this plant has potential as a raw material for herbal medicine. The purpose of this review is to evaluate the pharmacological activity and phytochemical content of water hyacinth based on current scientific literature. The method used was journal search and selection from 2021 to 2025 through PubMed, Google Scholar and ResearchGate databases with the keywords “Eichhornia crassipes”, ‘pharmacology’, and “bioactivity”. The results review showed water hyacinth extract has anti-inflammatory activity through decreasing proinflammatory cytokines, antidiabetic through activating SUR-1, GLP-1R, AMPK, and OCT-1 receptors and antibacterial against Prevotella intermedia and Staphylococcus aureus. In addition, anticancer activity was demonstrated through binding of active compounds to MCF-7 cancer cell receptors, as well as cytoprotective activity against oxidative stress in rat liver cells.
Formulation and Physical Evaluation of Leaves Extract Syrup Sungkai (Peronema canescens Jack.) Tri Budi Julianti; Renita Mahardhika Putri
Pharmacon: Jurnal Farmasi Indonesia Vol. 23 No. 1 (2026)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v23i1.12320

Abstract

Sungkai (Peronema canescens Jack) is a native Indonesian plant, particularly characteristic of Kalimantan, whose leaves are widely used by local communities as traditional medicine for treating fever, minor wounds, mouthwash, and enhancing the immune system. Previous phytochemical investigations reveal that sungkai leaves contain flavonoids, alkaloids, terpenoids, saponins, and tannins. This study was conducted by formulate syrup preparations with varying concentrations of extract as the active ingredient: 0% in formula 1, 0.1% in formula 2, 0.2% in formula 3, and 0.3% in formula 4, with the addition excipients such as stabilizer, preservative, flavoring, sweetener, aroma and solvent. Each formulation underwent triplicate physical evaluations comprising organoleptic properties, clarity, homogeneity, pH, specific gravity, displaced volume, pouring time, and viscosity as well as statistical analysis results to find out the standard syrup quality criteria. All four formulations met the established physical quality standards for syrup. Notably, Formula 2 containing 0.1% extract as the active ingredient demonstrated superior physical stability, particularly evident in viscosity profile. This formulation presents a promising natural based alternative for further development in immunomodulatory efficacy studies.
Co-Authors Amalia Pratamasari H.N.M Amalia, Nastity Zhahwa Andi Daramusseng Arifah Sri Wahyuni Asri Dwi Endah Dewi Pramesthi Astuti, Devi Dwi Dea Puspita Dewi Dewi Lutfania Syahrani Dwi Endah Dewi Pramesthi, Asri Erindyah Retno Wikantyasning Febi Sabrina Febi Sabrina Hairunisa, Indah Hasanah, Rizkiatul Herlita Wulandari Husniyah, Susy Ika Ayu Mentari Javier Ammar Marchelin Tri Oktaviani Melda Mubina Ali Mubina Ali, Melda Nurjunnah, Rika Pratamasari H.N.M, Amalia Puspita Dewi, Dea Putri, Nastity Zhahwa Amalia Rahma Azkiah Rahma Azkiah Rahmawati Safitri Rahmawati Safitri Raodhatul Jannah Raodhatul Jannah Renita Mahardhika Putri Rizki Nur Azmi Rizkiatul Hasanah Salsabila Azzahra Sayutri, Zelvisya Siti Khadijah Susy Husniyah Syarifah Nur Oktarina Putri Sylvan Septian Ressandy Tania Putri Tri Oktaviani, Marchelin Wulandari, Herlita Zelvisya Sayutri